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*  Thymidylate synthase
However, due to a low level of 5-FU found in many patients, it has been discovered that in combination with leucovorin (LV), 5- ... "Leucovorin". MedlinePlus Drug Information. U.S. National Library of Medicine. Papamichael D (2000). "The Use of Thymidylate ...
*  Folinic acid
Selective inhibition of leucovorin reactivation of dihydrofolate reductase and leucovorin utilization in purine and pyrimidine ... "Leucovorin Calcium". The American Society of Health-System Pharmacists. Archived from the original on 10 May 2017. Retrieved 8 ... Folinic acid, also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate and pyrimethamine. ... Trissel, L. A.; Martinez, J. F.; Xu, Q. A. (1995). "Incompatibility of fluorouracil with leucovorin calcium or levoleucovorin ...
*  FOLFOXIRI
Also, the doses (Day 1: irinotecan 165 mg/m2 IV, plus oxaliplatin 85 mg/m2 IV; Day 1: leucovorin 400 mg/m2; Days 1-3: ... The chemotherapy regimen is made up of the following four drugs: FOL - folinic acid (leucovorin), a vitamin B derivative that ... 2007). "Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with ... infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the ...
*  Levoleucovorin
Kovoor, P. A.; Karim, S. M.; Marshall, J. L. (2009). "Is levoleucovorin an alternative to racemic leucovorin? A literature ...
*  Hereditary folate malabsorption
The racemic mixture of 5-formyltetrahydrofolate (leucovorin) is generally available; the active S-isomer, levoleucovorin, may ...
*  Trimetrexate
January 1990). "Trimetrexate-leucovorin dosage evaluation study for treatment of Pneumocystis carinii pneumonia". J. Infect. ... It has been used with leucovorin in treating pneumocystis pneumonia. It has been investigated for use in treating ...
*  Primary central nervous system lymphoma
Leucovorin is often given for the duration of the therapy. Standard chemotherapeutic regimens for lymphoma such as CHOP are ... The addition of IV methotrexate and folinic acid (leucovorin) may extend survival to a median of 3.5 years. If radiation is ...
*  Aminopterin
Leucovorin has been used in rats, dogs and humans to rescue aminopterin toxicity. Leucovorin rescue is a therapeutic maneuver ... leucovorin rescue at overdosages lower than 10 mg aminopterin in an average 70 kg adult should comprise an initial leucovorin ... However, rescue with leucovorin should form the backbone of treatment. The vitamin folic acid is an oxidized precursor to ... leucovorin rescue abortions in pregnant women Supralethal doses of aminopterin may be rescued with the antidote Leucovorin ( ...
*  Steven Eisenberg
"Improving the toxicity of irinotecan/5-FU/leucovorin: a 21-day schedule.", Oncology (Huntingt), September 2003; 17(9 Suppl 8): ... and Leucovorin: Possible Solution to Reduce Toxicity?", Advances in Colon Cancer, 2001; 5(2):3-6. Eisenberg SG, Marshall JL. " ... and Leucovorin. Since 2005, Eisenberg has focused his practice on compassion and empathy in clinical oncology. In 2011, ...
*  Tegafur/gimeracil/oteracil
Tegafur Gimeracil Oteracil potassium TS-1.jp, Taiho Pharmaceutical Liu TW, Chen LT (201). "S-1 with leucovorin for gastric ...
*  Glutamate carboxypeptidase
... and leucovorin". J. Bacteriol. 134: 506-513. PMC 222280 . PMID 26657. Sherwood, R.F.; Melton, R.G.; Alwan, S.A. (1985). " ...
*  Folate receptor 1
Recent studies have shown that these neurodevelopmental disorders can be treated with leucovorin calcium. SLC19A1 ONX-0801 ...
*  Hyper-CVAD
Leucovorin is used as a 'rescue' agent to prevent excessive cellular damage by methotrexate. Sodium bicarbonate 600 mg PO ( ... 12 mg IT Day 2 Methotrexate 1000 mg/m2 IV over 24 hours Day 1 Leucovorin 25 mg/ m2 IV 24 hours after starting methotrexate ...
*  Cholangiocarcinoma
Choi C, Choi I, Seo J, Kim B, Kim J, Kim C, Um S, Kim J, Kim Y (2000). "Effects of 5-fluorouracil and leucovorin in the ... Chemotherapy agents used to treat cholangiocarcinoma include 5-fluorouracil with leucovorin, gemcitabine as a single agent, or ...
*  Oxaliplatin
2000). "Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer". J Clin ... Often it is used together with fluorouracil and folinic acid (leucovorin) in advanced cancer. It is given by injection into a ...
*  Irinotecan
Guo, Y; Shi, M; Shen, X; Yang, C; Yang, L; Zhang, J (2014). "Capecitabine plus irinotecan versus 5-FU/leucovorin plus ... This includes the regimen FOLFIRI, which consists of infusional 5-fluorouracil, leucovorin, and irinotecan. The regimen XELIRI ...
*  FOLFOX
Day 2: Leucovorin 200 mg/m² IV infusion over 120 minutes, followed by 5-FU 400 mg/m² IV bolus given over 2-4 minutes, followed ... FOLFOX is a chemotherapy regimen for treatment of colorectal cancer, made up of the drugs FOL- Folinic acid (leucovorin) F - ... concurrent with leucovorin 400 mg/m² (or levoleucovorin 200 mg/m²) IV infusion, followed by 5-FU 400 mg/m² IV bolus, followed ... Oxaliplatin 85 mg/m² IV infusion in 250-500 mL D5W and leucovorin 200 mg/m² IV infusion in D5W both given over 120 minutes at ...
*  Urachal cancer
... irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab". Urology Case Reports. 3 (2): 9-11. doi:10.1016/j.eucr.2014.11.004 ...
*  KRAS
... leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer". Journal of ...
*  Pyrimethamine
Folinic acid (leucovorin) is a folic acid derivative converted to tetrahydrofolate, the primary active form of folic acid, in ... Pyrimethamine, sold under the trade name Daraprim, is a medication used with leucovorin to treat toxoplasmosis and ... "Imprimis Pharmaceuticals to Make Compounded and Customizable Formulation of Pyrimethamine and Leucovorin Available for ... Pharmaceuticals announced it has made available compounded and customizable formulations of pyrimethamine and leucovorin in ...
*  STAT6
... the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer". ...
*  Gastrointestinal intraepithelial neoplasia
The addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer". ...
*  Concomitant drug
Both consist of 3 medicinal drugs: a) Leucovorin (= folinic acid = calcium folinate), b) 5-Fluorouracil (= 5-FU), and c) ...
*  Tegafur/uracil
September 2004). "Comparison of the efficacy, toxicity, and pharmacokinetics of a uracil/tegafur (UFT) plus oral leucovorin (LV ... "Biweekly oxaliplatin plus 1-day infusional fluorouracil/leucovorin followed by metronomic chemotherapy with tegafur/uracil in ...