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*  Thujone
The median lethal dose, or LD50, of alpha-thujone, the more active of the two isomers, in mice, is around 45 mg/kg, with 0% ... Pretreatment with diazepam, phenobarbital, or 1 g/kg of ethanol protects against a lethal dose of 100 mg/kg. These effects are ... The high dose had a short-term negative effect on attention performance. The lower dose showed no noticeable effect. Thujone is ... Mice exposed to the higher dose have convulsions that lead to death within 1 minute. From 30 to 45 mg/kg, the mice experience ...
*  LD 50 Lethal Dose
... was a 2003 horror film directed by Simon De Selva, produced by Alistair MacLean-Clark and Basil Stephens and ... "LD 50 Lethal Dose (2003) Movie Review". Beyond Hollywood. 31 May 2004. Retrieved 31 July 2012. LD 50 Lethal Dose on IMDb Lethal ...
*  Testing cosmetics on animals
Rats and mice are injected in lethal dose 50% (LD50). This test can cause animal convulsions, loss of motor function, and ... which refers to the lethal dose which kills 50% of the treated animals). Skin corrosivity or irritation: This method of test ...
*  Tebufenpyrad
Interestingly, the Lethal Dose 50(LD50) values of male and female rats was very different. While the LD50 value of female rats ... The LD 50 values for various laboratory animals are as follows: LD50 Rat (male) oral 595 mg/kg LD50 Rat (female) oral 997 mg/kg ... This vast difference in LD 50 value might be attributed to this biotransformation. Tebufenpyrad exposure has been linked to ...
*  PH10
Mayo, James (1997-03-13). "Lethal Dose: LD-50 makes electronic music that doesn't go down smooth". Denver Westword. Retrieved ... LD-50. Their debut release, "Recone Helmut vs. Clark ov Saturn" was one of the Denver Westword's "20 best recordings to come ...
*  Clark Saturn
Mayo, James (1997-03-13). "Lethal Dose: LD-50 makes electronic music that doesn't go down smooth". Denver Westword. Retrieved ... After joining the industrial band LD-50, Saturn and Recone Helmut split off and formed pH10 and moved to New York City in 1999 ... and LD-50. Saturn was a resident DJ in Brooklyn, NY at Halcyon's Sunday evening "Undercity" party, along with DJs Spinoza, ...
*  Bilastine
After intravenous administration, LD50 (lethal dose for 50% of animals) values were 33 and 45-75 mg/kg in mice and rats, ... up to 11 times the therapeutic dose), nor at multiple doses (up to 10 times the therapeutic dose). Phase II and III studies on ... At doses of 20 mg was highly effective (P < 0.0001) in reducing CTT. Up-dosing to 80 mg significantly (P < 0.04) increased its ... Ninety six percent of the administered dose is eliminated within 24 hours. In relation to its antihistamine effect, oral doses ...
*  Diazepam
The oral LD50 (lethal dose in 50% of the population) of diazepam is 720 mg/kg in mice and 1240 mg/kg in rats. D. J. Greenblatt ... Dose increases may overcome the effects of tolerance, but tolerance may then develop to the higher dose and adverse effects may ... Doses of diazepam are recommended to be about half of those given to younger people, and treatment limited to a maximum of two ... Continual daily doses of diazepam quickly build to a high concentration in the body (mainly in adipose tissue), far in excess ...
*  Snake venom
It results in far more accurate and consistent median lethal dose (LD50) determinations than for example using 0.1% saline as a ... "lethal dose, 50%"), which determines the concentration of a toxin required to kill half the members of a tested population of ... IPR003572 The toxicity of snake venom is assessed by a toxicological test called the median lethal dose, LD50, (an abbreviation ... A complex mixture of proteins, enzymes, and various other substances with toxic and lethal properties serves to immobilize the ...
*  Median lethal dose
In toxicology, the median lethal dose, LD50 (abbreviation for "lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 is ... this also means that LD50 is not the lethal dose for all subjects; some may be killed by much less, while others survive doses ... a measure of the lethal dose of a toxin, radiation, or pathogen. The value of LD50 for a substance is the dose required to kill ... For disease-causing organisms, there is also a measure known as the median infective dose and dosage. The median infective dose ...
*  Recreational use of dextromethorphan
In 1981, a paper by Gosselin estimated that the lethal dose is between 50 and 500 mg/kg. Doses as high as 15-20 mg/kg are taken ... In addition to producing PCP-like mental effects, high doses may cause a false-positive result for PCP and opiates in some drug ... At high doses, dextromethorphan is classified as a dissociative general anesthetic and hallucinogen, similar to the controlled ... It has almost no psychoactive effects at medically recommended doses. Dextromethorphan has powerful dissociative properties ...
*  Pesticide toxicity to bees
Primary measurement endpoint derived from the acute oral and acute contact toxicity studies is the median lethal dose for 50% ... The pesticide concentration was order of magnitudes smaller than the lethal dose used in the pesticide's current use. The ... The acute toxicity, although more lethal, is less common than sub-lethal toxicity or cumulative effects. Field exposure of bees ... Sub-lethal effects to honey bees are of major concern and include behavioral disruptions such as disorientation, reduced ...
*  Cyanuric acid
... oral median lethal dose (LD50) is 7700 mg/kg in rats. However, when cyanuric acid is present together with melamine (which by ... It binds to free chlorine and releases it slowly, extending the time needed to deplete each dose of sanitizer. The ...
*  Bambusa vulgaris
It is highly toxic, and the lethal dose for humans is about 50-60 mg. A dose of 25 mg cyanogenic glycoside fed to rats (100-120 ... page 50, Applewood Books, 2008, ISBN 978-1-4290-1281-2 MT Yakubu and BB Bukoye, "Abortifacient potentials of the aqueous ...
*  Dimethyl tetrachloroterephthalate
... lethal dose of DCPA, is 12,500 mg/kg in spartan rats, and greater than 10,000 mg/kg in beagle dogs. In humans, it seems that ... but at lower doses than necessary for DCPA. TPA does not degrade, and infiltrates soil and nearby water sources. The ... mainly weight loss and diarrhea occurring at doses of 2000 mg/kg/day. There were also effects on the lungs, liver, kidney, and ... DCPA is poorly absorbed, as 6% of a 25-mg dose and 12% of a 50-mg dose were absorbed according to metabolites in urine. ...
*  LD50 (disambiguation)
LD50 is the median lethal dose in toxicology. LD50 may also refer to: L.D. 50 (album), an album by Mudvayne LD 50 Lethal Dose, ...
*  Tania Emery
She had roles in the films LD 50 Lethal Dose and Den of Lions, and in 2004 appeared as Frida in a stage production of Luigi ...
*  Philip Winchester
He is known for his roles in The Patriot, The Hi-Line, LD 50 Lethal Dose, Thunderbirds, CSI: Miami, King Lear, Strike Back, ...
*  L.A. State of Mind
"LD50: Lethal Dose DVD". Amazon.com. "Melanie Brown, LA State of Mind (Amber Cafe)". The Guardian. 23 June 2005. Retrieved 17 ... presenting the TV show This Is My Moment and recording the films LD 50 Lethal Dose, The Seat Filler, Telling Lies and the ...
*  Camphor
Lethal doses in adults are in the range 50-500 mg/kg (orally). Generally, two grams cause serious toxicity and four grams are ... Camphor is toxic in large doses. It produces symptoms of irritability, disorientation, lethargy, muscle spasms, vomiting, ... potentially lethal. Camphor has been used in traditional medicine from time immemorial in countries where it was native. It was ... In the 20th century, camphor was administered orally in small quantities (50 mg) for minor heart symptoms and fatigue. This ...
*  Doxylamine
The median lethal dose (LD50) is estimated to be 50-500 mg/kg in humans. Symptoms of overdose may include dry mouth, dilated ... A toxic dose for children of more than 1.8 mg/kg has been reported. A 3-year old child died 18 hours after ingesting 1,000 mg ... This action is responsible for the anticholinergic and, at high doses, deliriant effects of doxylamine. The bioavailability of ... "Comparative pharmacokinetics of single doses of doxylamine succinate following intranasal, oral and intravenous administration ...
*  Moraxella osloensis
... lethal dose of 48 μg when injected into the shell cavity. Although M. osloensis rarely infects humans, it can sometimes be ... and the purified lipopolysaccharide was toxic to the slug with an estimated 50% ...
*  MRI contrast agent
... lethal dose, but the LD50 is increased by a factor of 100 when Gd (III) is chelated, so that its toxicity becomes comparable to ... For large vessels such as the aorta and its branches, the gadolinium(III) dose can be as low as 0.1 mmol per kg body mass. ... Because gadolinium-based contrast agents pass the blood-brain barrier and of each bolus dose at least 1% of the gadolinium is ... with High Dose Efficiency and Capability for Molecular Imaging of Cancer Biomarkers". Medicinal Research Reviews. 34 (5): 1070- ...
*  Gamma ray
A dose of 5 Sv (5 Gy) is considered approximately the LD50 (lethal dose for 50% of exposed population) for an acute exposure to ... "Lethal dose", NRC Glossary (October 18, 2011) Cardis, E (9 July 2005). "Risk of cancer after low doses of ionising radiation: ... For gamma rays, it is equal to the absorbed dose. The sievert (Sv) is the SI unit of equivalent dose, which for gamma rays is ... This is called the absorbed dose: The gray (Gy), which has units of joules per kilogram (J/kg), is the SI unit of absorbed dose ...
*  List of dangerous snakes
The median lethal dose (LD50) of a venom is the dose required to kill half the members of a tested population after a specified ... The median lethal dose (LD50) is 0.28-0.33 mg per gram of mouse body weight. In case of IV the LD50 is 0.373 mg/kg, and 0.225 ... Average venom yield is 80-120 mg and the murine LD50 is 1.1-1.6 mg/kg SC with an estimated lethal dose for humans of 50-60 mg. ... It may inject as much as 12 mg, whereas the lethal dose for an adult human is estimated to be only 5 mg. Envenomation results ...
*  Senescence
Importantly, these drugs had long term effects after a single dose, consistent with removal of senescent cells, rather than a ... Therefore, natural selection can support lethal and harmful alleles, if their expression occurs after reproduction. Senescence ... Sub-lethal damage Transgenerational design Stem cell theory of aging Timeline of senescence research Ainsworth, C; Lepage, M ( ... 21: 29-50. PMID 4860956. Gensler HL; Bernstein H (September 1981). "DNA damage as the primary cause of aging". Q Rev Biol. 56 ( ...
*  Lethal dose
The median lethal dose, LD50 (abbreviation for "lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 (lethal ... Because resistance varies from one individual to another, the "lethal dose" represents a dose (usually recorded as dose per ... In toxicology, the lethal dose (LD) is an indication of the lethal toxicity of a given substance or type of radiation. ... The lethal concentration is a lethal dose measurement used for gases or particulates. The LD may be based on the standard ...