ISBN 978-1-4511-0563-6. ICTV taxonomy of Lentivirus "Lentiviruses In Ungulates. I. General Features, History And Prevalence" ( ... Lentiviruses are distributed worldwide, and are known to be hosted in apes, cows, goats, horses, cats, and sheep as well as ... Lentivirus is primarily a research tool used to introduce a gene product into in vitro systems or animal models. Large-scale ... Lentiviruses can integrate a significant amount of viral complementary DNA into the DNA of the host cell and can efficiently ...
... (PLV) is a retrovirus. A study in 2003 indicated that domestic cats infected with Puma lentivirus or Lion ... VandeWoude S, Hageman CL, Hoover EA (September 2003). "Domestic cats infected with lion or puma lentivirus develop anti-feline ... lentivirus (LLV) began producing anti-FIV immune responses. ...
In gene therapy, adenoviruses differ from lentiviruses in many ways, some of which provide advantages over lentiviruses. ... The lentivirus is a retrovirus, meaning it has a single stranded RNA genome with a reverse transcriptase enzyme. Lentiviruses ... or deleted in organisms using lentiviruses. Lentiviruses are a family of viruses that are responsible for diseases like AIDS, ... More specifically, lentiviruses attach to the CD4 glycoproteins on the surface of a host's target cell. The viral material is ...
One of the identifying characteristics of lentiviruses is being able to infect non-dividing cells. BIV, being a lentivirus has ... Bovine immunodeficiency virus (BIV) is a retrovirus belonging to the genus Lentivirus. It is similar to the human ... In primate lentiviruses there is usually an ORF for nef (negative factor); this is not present in BIV. BIV has a structure like ... a comparison with other lentiviruses". Anim Health Res Rev. 5 (2): 125-43. doi:10.1079/ahr200496. PMID 15984320. Gonda MA (1992 ...
Dull T, Zufferey R, Kelly M, Mandel RJ, Nguyen M, Trono D, Naldini L (November 1998). "A third-generation lentivirus vector ... producing sufficient amounts of high-quality lentivirus; (v) overcoming low transformation efficiency; (vi) proper scaling of ...
Katzourakis A, Tristem M, Pybus OG, Gifford RJ (April 2007). "Discovery and analysis of the first endogenous lentivirus". ... and 12 million years for the Lentivirus genus of the Retroviridae family. EVEs also facilitate the use of molecular clock-based ...
"Evolution of the primate lentiviruses: evidence from vpx and vpr." The EMBO journal 11, no. 9 (1992): 3405-3412. Marshall, ... "Origin of vpx in lentiviruses." Nature 347, no. 6291 (1990): 341-342. Denton, Michael, and Craig Marshall. "Laws of form ...
Poli, A.; Abramo, F.; Cavicchio, P.; Bandecchi, P.; Ghelardi, E.; Pistello, M. (1995). "Lentivirus infection in an African lion ... Feline immunodeficiency virus and lentivirus also affect captive lions. When resting, lion socialisation occurs through a ...
... (also known as Visna virus, Maedi-visna virus and Ovine lentivirus) from the genus Lentivirus and subfamily ... This causal lentivirus can be found in monocytes, lymphocytes and macrophages of infected sheep in the presence of humoral and ... The dUTPase enzyme is not present in all lentiviruses. The role of the dUTPase in the visna virus life cycle is unclear. ... The visna virus genome resembles that of other lentiviruses, in terms of the gene functions that are present. Visna virus is ...
Additionally, lentiviruses are also highly endemic in Africa infecting not only felids, but also primates, and ungulate species ... FIV and HIV are both lentiviruses. However, humans cannot be infected by FIV, nor can cats be infected by HIV. FIV is ... FIV displays a similar structure to the primate and ungulate lentiviruses. The virion has a diameter from 80 to 100 nanometers ... In common with other lentiviruses, the FIV genome encodes additional short open reading frames (ORFs) encoding the Vif and Rev ...
Lentiviruses such as HIV-1 have acquired proteins such as Nef which perform a wide array of functions including the ... Piguet V, Trono D (1999). "The Nef protein of primate lentiviruses". Rev. Med. Virol. 9 (2): 111-20. doi:10.1002/(SICI)1099- ... Nef (Negative Regulatory Factor) is a small 27-35 kDa myristoylated protein encoded by primate lentiviruses. These include ...
... which raises concerns for possible applications of lentiviruses in gene therapy. However, studies have shown that lentivirus ... To produce a lentivirus, several plasmids are transfected into a so-called packaging cell line, commonly HEK 293. One or more ... Lentiviruses are a subclass of retroviruses. They are sometimes used as vectors for gene therapy thanks to their ability to ... As opposed to lentiviruses, adenoviral DNA does not integrate into the genome and is not replicated during cell division.: 5 ...
Bulliard Y, Wiznerowicz M, Barde I, Trono D (Nov 2006). "KRAB can repress lentivirus proviral transcription independently of ...
"A transitional endogenous lentivirus from the genome of a basal primate and implications for lentivirus evolution". Proceedings ... The simian (monkey-hosted) immunodeficiency viruses are a species of retrovirus in the Primate group of genus Lentivirus along ... In 2008, discovery of an endogenous lentivirus in a prosimian (proto-monkey) primate, the gray mouse lemur native to Madagascar ... Peeters M, Courgnaud V, Abela B (2001). "Genetic Diversity of Lentiviruses in Non-Human Primates" (PDF). AIDS Reviews. 3: 3-10 ...
The virus is a lentivirus, like human immunodeficiency virus (HIV). Like HIV, EIA can be transmitted through blood, milk, and ...
Desport, Moira (2010). Lentiviruses and Macrophages: Molecular and Cellular Interactions. Horizon Scientific Press. ISBN ...
This is unlike Lentivirus, a genus of Retroviridae, which are able to integrate their RNA into the genome of non-dividing host ... The lentivirus genus, the spumavirus genus, the HTLV / bovine leukemia virus (BLV) genus, and a newly introduced fish virus ... Lentiviruses (slow viruses) include HIV-1 and HIV-2, the cause of acquired immune deficiency syndrome (AIDS) in humans. ... 2010). Lentiviruses and Macrophages: Molecular and Cellular Interactions. Caister Academic. ISBN 978-1-904455-60-8. Ross, S. R ...
The disease was later determined to be caused by a lentivirus. Domesticated banteng were first introduced to Australia in 1849 ...
Gifford, Robert J. (2012-02-01). "Viral evolution in deep time: lentiviruses and mammals". Trends in Genetics. 28 (2): 89-100. ...
Most commonly, this is done using a lentivirus that encodes the transgene. Pseudotyped, self-inactivating lentiviruses are an ... December 1998). "Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery". Journal of Virology. 72 (12 ...
Robertson JS, Cichutek K. Dev Biol (Basel). 2000; 104:53-6. PMID 11713824 A novel lentivirus vector derived from apathogenic ...
While lentivirus transduction generally causes lower genotoxicity but with lower transfection efficiency. Main article: see ...
Lentiviruses integrate into sections of transcriptionally active chromatin and are thus passed on to progeny cells. With this ... and lentiviruses. With adeno-associated viruses and adenoviruses, the genomes remain episomal. This is advantageous as ... the risk can be reduced by using an integrase-deficient lentivirus. Once the vector has integrated into the host genome, the ...
Additionally, these viruses have been identified in animals that most often carry lentiviruses. The name foamy virus can be ... While replication is similar to lentiviruses with regards to the aforementioned promoter regions, it is also similar to the ... Current research may suggest that equine foamy virus serves as a cofactor in the contraction of equine lentivirus infection. ... It shares similarities, with respect to replication, with lentiviruses. EFV, along with other FVs are from the family ...
Dunham SP (2006). "Lessons from the cat: development of vaccines against lentiviruses". Veterinary Immunology and ...
Lentiviruses have many morphologies and biological properties in common. Many species are infected by lentiviruses, which are ... Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses. Upon entry into the target cell, the ... Chen J, Powell D, Hu WS (2006). "High frequency of genetic recombination is a common feature of primate lentivirus replication ... The human immunodeficiency viruses (HIV) are two species of Lentivirus (a subgroup of retrovirus) that infect humans. Over time ...
... insights from animal lentiviruses". Journal of Virology. 74 (16): 7187-95. doi:10.1128/JVI.74.16.7187-7195.2000. PMC 112239. ...
... Therapeutic haemoglobin synthesis in β-thalassaemic mice expressing lentivirus-encoded human β-globin, Nature ... "Therapeutic haemoglobin synthesis in β-thalassaemic mice expressing lentivirus-encoded human β-globin". Nature. 406 (6791): 82- ...
Vectors like lentivirus and adeno-associated virus have been used in this method. This method allows for targeting of ...
Wang T, Hao L, Feng Y, Wang G, Qin D, Gu G (2011). "Knockdown of MED19 by lentivirus-mediated shRNA in human osteosarcoma cells ... Li LH, He J, Hua D, Guo ZJ, Gao Q (2011). "Lentivirus-mediated inhibition of Med19 suppresses growth of breast cancer cells in ...