Currently, the only protein known to interact with podoplanin physiologically is CLEC-2, a C-type lectin 2 expressed on ... It is often upregulated in certain types of cancer, including several types of squamous cell carcinomas, malignant mesothelioma ... Podoplanin is a mucin-type protein with a mass of 36- to 43-kDa. It is relatively well conserved between species, with ... The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species ...

v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 1, C-type lectins, ... "The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein- ... "The proteoglycans aggrecan and Versican form networks with fibulin-2 through their lectin domain binding". The Journal of ...

Endocytic PRRs on phagocytes reflect these molecular patterns, with C-type lectin receptors binding to mannans and β-glucans, ... Inflammation has also been classified as Type 1 and Type 2 based on the type of cytokines and helper T cells (Th1 and Th2) ... Prolonged inflammation, known as chronic inflammation, leads to a progressive shift in the type of cells present at the site of ... ROS, alone, cause more than 20 types of DNA damage. Oxidative DNA damages cause both mutations and epigenetic alterations. RNS ...

PrP antibodies and selected lectins bound to the same protein in both normal and CJD and scrapie infected brain fractions. ... These culture studies further showed that PrP band patterns are cell-type dependent. Only rare strains show a PrP folding ... were the first to show that prion protein amyloid was derived from a glycosylated 34kd precursor protein using lectins. ...

... the C-type lectins called DC-SIGN, mannose receptor and CLEC5A. DC-SIGN, a non-specific receptor for foreign material on ... The virus has five serotypes; infection with one type usually gives lifelong immunity to that type, but only short-term ... Two types of dengue vaccine have been approved and are commercially available. On 5 December 2022 the European Medicines Agency ... Two types of dengue vaccine are available: Qdenga and Dengvaxia. On 5 December 2022 the European Medicines Agency approved ...

... like and C-type lectin-like domains". The Journal of Biological Chemistry. 267 (20): 14109-17. PMID 1629211. Russellysin at the ...

CCT also directly interacts with lectin type oxidized LDL receptor-1 (LOX-1) while its ligand oxidized low density lipoprotein ...

... is a lectin-like type II transmembrane receptor expressed by natural killer cells". European Journal of Immunology. 28 (12): ... Killer cell lectin-like receptor subfamily G member 1 is a protein that in humans is encoded by the KLRG1 gene. Natural killer ... Ibegbu CC, Xu YX, Harris W, Maggio D, Miller JD, Kourtis AP (May 2005). "Expression of killer cell lectin-like receptor G1 on ... The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of ...

December 2001). "BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a ... C-type lectins, All stub articles, Human chromosome 12 gene stubs). ...

Land A, Braakman I (2001). "Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic ... 1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins". Jpn. J. Med. Sci. Biol. 43 (3): 75-87. doi:10.7883/ ... Dedera DA, Gu RL, Ratner L (1992). "Role of asparagine-linked glycosylation in human immunodeficiency virus type 1 ... Dewar RL, Vasudevachari MB, Natarajan V, Salzman NP (1989). "Biosynthesis and processing of human immunodeficiency virus type 1 ...

C-type lectins are a diverse superfamily of mainly Ca2+-dependent proteins that bind a variety of carbohydrates (including the ... The different peptidoglycan types of bacterial cell walls and their taxonomic implications have been described. Archaea (domain ... In mammals, they initiate the lectin-pathway of the complement cascade. The role of TLRs in direct recognition of peptidoglycan ... NOD1 is expressed by diverse cell types, including myeloid phagocytes, epithelial cells and neurons. NOD2 is expressed in ...

The monomer of this protein has structural similarity to several members of the beta-galactoside-binding S-type lectin family, ... Overview of all the structural information available in the PDB for UniProt: Q9UHV8 (Human Galactoside-binding soluble lectin ...

... aggrecan and CD44 is similar to that of the C-type lectin superfamily". FEBS Lett. 388 (2-3): 211-6. doi:10.1016/0014-5793(96) ... of two alpha helices and two antiparallel beta sheets arranged around a large hydrophobic core similar to that of C-type lectin ...

1991). "Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins". Jpn. J. Med. Sci. ... 1990). "Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1". AIDS Res. Hum. ... Land A, Braakman I (2001). "Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic ... Dedera DA, Gu RL, Ratner L (1992). "Role of asparagine-linked glycosylation in human immunodeficiency virus type 1 ...

1991). "Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins". Jpn. J. Med. Sci. ... 1996). "Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of ... 1998). "Stage-specific expression of a mouse homologue of the porcine 135kDa alpha-D-mannosidase (MAN2B2) in type A ... 1990). "Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1". AIDS Res. Hum. ...

1991). "Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins". Jpn. J. Med. Sci. ... 1996). "Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of ... 1990). "Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1". AIDS Res. Hum. ... Dedera DA, Gu RL, Ratner L (1992). "Role of asparagine-linked glycosylation in human immunodeficiency virus type 1 ...

... displayed reduced paucimannosidic protein levels and altered sensitivity towards nematotoxic lectins relative to wild-type ... and complex-type N-glycans. Paucimannosylation has traditionally been referred to as a N-glycosylation type of "lower organisms ... Pak, Joanne; Pu, Yongbing; Zhang, Zhong-Ting; Hasty, David L.; Wu, Xue-Ru (March 2001). "Tamm-Horsfall Protein Binds to Type 1 ... To this end, paucimannosylation is therefore now considered to be a distinct type of N-glycosylation that adds diversity to the ...

... which can induce the host to produce antimicrobial C-type lectins REGIIIγ and REGIIIβ, both anti-microbial peptides that target ... "Symbiotic bacteria direct expression of an intestinal bactericidal lectin". Science. 313 (5790): 1126-1130. Bibcode:2006Sci... ...

The protein is highly stable, unfolding only at high temperatures All jacalin-related lectins feature type I beta-prism folding ... BanLec (also BanLec-I or Banana lectin) is a lectin from the jacalin-related lectin family isolated from the fruit of the ... Crystal structures of BanLec suggest that the lectin has two saccharide binding sites. In 2010, BanLec was reported to be a ... Swanson MD, Winter HC, Goldstein IJ, Markovitz DM (March 2010). "A Lectin Isolated from Bananas Is a Potent Inhibitor of HIV ...

T. canis C-type lectins are additionally able to bind to mammalian carbohydrates, suggesting that they may promote evasion of ... This result supports the possibility of eventually using helminth products to treat type I diabetes in humans as well. Freedman ... Additionally, injection of proteins secreted by Fasciola hepatica in nonobese diabetic mice prevented the onset of type I ... a type of NPA) requires an aqueous diffusion step. Sj-FABPc uses a collision mechanism, and transfer is not affected by ...

C-type lectins, All stub articles, Biochemistry stubs). ... and was the first mammalian lectin identified. The researchers ... Gupta GS (2012). Gupta GS (ed.). Animal Lectins: Form, Function and Clinical Applications. Wien: Springer-Verlag. doi:10.1007/ ... The asialoglycoprotein receptors (ASGPR) are lectins which bind asialoglycoprotein and glycoproteins from which a sialic acid ...

C-type lectins SP-A SP-D Iron metabolism proteins Lactoferrin Kinocidins CCL20/Mip-3-alpha Defensins Database, Singapore Innate ...

During the 1940s, Boyd and Karl O. Renkonen independently discovered that lectins react differently to various blood types, ... His work led him to discover that peptic ulcer was more dominant in blood group O, and that AB blood type mothers had a high ... A majority of his work was researching the links of blood types to sex, disease, climate, age, social class, and race. ... Espino-Solis, Gerardo Pavel (April 2015). "Lectins: A brief review". Vitae. 22 (1): 9-11. doi:10.17533/udea.vitae.v22n1a01. ...

The underlying hypothesis of blood type diets is that people with different blood types digest lectins differently, and that if ... Moreira point out that assertions made by proponents of blood type diets that the O blood type was the first human blood type ... Blood type Blood type personality theory List of diets Baldwin, EJ (2004). "Fad diets in diabetes". Br J Diabetes Vasc Dis. 4 ( ... Edward Blonz (2003-03-18). "Book Review: Eat Right 4 Your Type (1996)". Quackwatch. Retrieved 2013-08-22. "blood type diet". ...

Mannose-binding lectins, or ficolins, along with pentraxins and collectins are able to recognize certain types of carbohydrates ... Opsonins are related to the two types of immune systems: the adaptive immune system and the innate immune system. Antibodies ... Collectin molecules such as mannose-binding lectin (MBL), surfactant protein A (SP-A), and SP-D interact with unknown ligands ... Different types of things ("targets") can be tagged by opsonins for phagocytosis, including: pathogens (such as bacteria), ...

v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 19, C-type lectins, ...

C-type lectins, Immune system, Transcription coregulators, Molecular chaperones). ... Calreticulin and Calnexin's ability to bind carbohydrates associates them with the lectin protein family. In normal cellular ...

Their life cycle is thought to begin with a virion attaching to specific cell-surface receptors such as C-type lectins, DC-SIGN ... The type 1 interferons are then released and bind to the IFNAR1 and IFNAR2 receptors expressed on the surface of a neighbouring ... Other types of white blood cells, such as lymphocytes, also undergo programmed cell death leading to an abnormally low ... Three types of fruit bats (Hypsignathus monstrosus, Epomops franqueti and Myonycteris torquata) were found to possibly carry ...

... "is the systematic study of all glycan structures of a given cell type or organism" and is a subset of glycobiology. ... However, the structure of the binding site of numerous lectins, enzymes and other carbohydrate-binding proteins has revealed a ... Proteins have 20 (the amino acids). Saccharides have 32 types of sugar linkages. While these building blocks can be attached ... There are important medical applications of aspects of glycomics: Lectins fractionate cells to avoid graft-versus-host disease ...

C-type lectins) as those responsible for the formation of eggshell and pancreatic stone crystals, but the role of C-type ... The calcium carbonate layers in a shell are generally of two types: an outer, chalk-like prismatic layer and an inner pearly, ... However, nacre does not seem to represent a modification of other shell types, as it uses a distinct set of proteins. The ... nacre is the most studied type of layer. In most shelled molluscs, the shell is large enough for all of the soft parts to be ...