A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes". Journal of ... Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells ... Iizuka K, Naidenko OV, Plougastel BF, Fremont DH, Yokoyama WM (August 2003). "Genetically linked C-type lectin-related ligands ... The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain ...

"A novel lectin from Pseudostellaria heterophylla roots with sequence simularity to Kunitz-type soybean trypsin inhibitor". Life ... A lectin in the roots is being studied for anti HIV purposes. This is a perennial herb with tubers and solitary erect stems up ...

Coombs PJ, Graham SA, Drickamer K, Taylor ME (June 2005). "Selective binding of the scavenger receptor C-type lectin to Lewisx ... containing ligands cleared by the scavenger receptor C-type lectin". J. Biol. Chem. 286 (27): 24336-49. doi:10.1074/jbc. ...

Different types of proteoglycans exist, depending on the sugar that is linked to the oxygen atom of the residue in the protein ... Terminal sugars on O-glycans are important in recognition by lectins and play a key role in the immune system. Addition of ... Type II keratan sulphate is especially common in cartilage. Galactose or glucose sugars can be attached to a hydroxyl group of ... Addition of a fucose alone creates the H-antigen, present in people with blood type O. By adding a galactose onto this ...

... inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin ... 2010). "The cytosolic beta-glucosidase GBA3 does not influence type 1 Gaucher disease manifestation". Blood Cells Mol. Dis. 46 ... Land A, Braakman I (2001). "Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic ... Pantophlet R, Wilson IA, Burton DR (2003). "Hyperglycosylated mutants of human immunodeficiency virus (HIV) type 1 monomeric ...

... inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin ... 1996). "Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of ... Land A, Braakman I (2001). "Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic ... 1993). "Functional role of the glycan cluster of the human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) ...

On December 21, 2007, a study published in PLoS Pathogens found the hemolytic C-type lectin CEL-III from Cucumaria echinata, a ... "Hemolytic C-type lectin CEL-III from sea cucumber expressed in transgenic mosquitoes impairs malaria parasite development". ... In the first type, the parasite is transmitted by the oral route and is relatively species nonspecific. In the second, while ... as well as housing type and local microclimatic conditions.[citation needed] Biting by nocturnal, endophagic Anopheles ...

2007). "Hemolytic C-Type Lectin CEL-III from Sea Cucumber Expressed inTransgenic Mosquitoes Impairs Malaria Parasite ... The body wall consists of an epidermis and a dermis and contains smaller calcareous ossicles, the types of which are ... One study found that a lectin from Cucumaria echinata impaired the development of the malaria parasite when produced by ...

... inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin ... 1996). "Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of ... "Entrez Gene: MANEA mannosidase, endo-alpha". Land A, Braakman I (2001). "Folding of the human immunodeficiency virus type 1 ... 1990). "Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1". AIDS Res. Hum. ...

Le Coq, J.; Ghosh, P. (2011-08-22). "Conservation of the C-type lectin fold for massive sequence variation in a Treponema ...

The two main proposed types of EGF-like domains are the human EGF-like (hEGF) domain and the complement C1r-like (cEGF) domain ... Phan UT, Waldron TT, Springer TA (2006). "Remodeling of the lectin-EGF-like domain interface in P- and L-selectin increases ... In many mitogenic and developmental proteins such as Notch and Delta the EGF-like domains are only of the hEGF type. Other ... The immature cells fail to activate T-cells and produce less interleukin 12 than wild-type dendritic cells. Phan et al. could ...

... inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin ... 1996). "Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of ... Dewar RL, Vasudevachari MB, Natarajan V, Salzman NP (1989). "Biosynthesis and processing of human immunodeficiency virus type 1 ... 1993). "Functional role of the glycan cluster of the human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) ...

... only type 2 RIPs display cytotoxicity due to the lectin-like properties of the B chain. To display its ribosome-inactivating ... Type 2 RIPs consist of an A chain that is functionally equivalent to a type 1 RIP, covalently connected by a single disulfide ... Ricin is classified as a type 2 ribosome-inactivating protein (RIP). Whereas type 1 RIPs are composed of a single protein chain ... Both type 1 and type 2 RIPs are functionally active against ribosomes in vitro; however, ...

... inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin ... 1996). "Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of ... Pantophlet R, Wilson IA, Burton DR (2003). "Hyperglycosylated Mutants of Human Immunodeficiency Virus (HIV) Type 1 Monomeric ... 1993). "Functional role of the glycan cluster of the human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) ...

December 2005). "The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity". Nature Immunology. 6 (12): 1245- ... a novel beta-galactoside-binding mammalian lectin". The Journal of Biological Chemistry. 272 (9): 6078-6086. doi:10.1074/jbc. ... or various cells in different tumor types. The receptor is an immune checkpoint and together with other inhibitory receptors ...

C-type lectin domain containing". Retrieved 2019-08-30. Geijtenbeek TB, Gringhuis SI (July 2009). "Signalling through C-type ... Lectin, Alternate Factor I - Classical, Lectin, Alternate C4BP - Classical, Lectin Factor H - Alternate Antimicrobial peptides ... TLR1 TLR2 TLR3 TLR4 TLR5 TLR6 TLR7 TLR8 TLR9 TLR10 TLR11 TLR12 TLR13 C-type lectin receptors (CLRs) Group 1 CLRs - Mannose ... Interferons Interferon type I IFN-α IFN-β IFN-ω Interferon type II IFN-γ Interleukins Tumor necrosis factors Colony stimulating ...

Nufer O, Mitrovic S, Hauri HP (Apr 2003). "Profile-based data base scanning for animal L-type lectins and characterization of ... "Entrez Gene: LMAN2 lectin, mannose-binding 2". Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap ... 2003). "Mannose-binding lectin polymorphisms in clinical tuberculosis". J. Infect. Dis. 188 (5): 777-82. doi:10.1086/377183. ...

These C-type lectins are associated with biomineralisation, and they are also found in extinct big bird shells collected from ... The best example is Type 1 collagen; it is one of the most abundant proteins in skin (80-85%) and bone (80-90%) extracellular ... Type 1 collagen has been routinely extracted from ancient bones, leathers, and parchments; these characteristics may contribute ... Fibrillar collagens are the most abundant proteins in modern bones; similarly, Type 1 and III collagens are also common in the ...

All cells are coated in either glycoproteins or glycolipids, both of which help determine cell types. Lectins, or proteins that ... A person with B blood type will have the B and H antigen present. A person with AB blood type will have A, B, and H antigens ... And finally, a person with O blood type will only have the H antigen present. This means all blood types have the H antigen, ... The various blood types are distinguished by the glycan modification present on the surface of blood cells. These can be ...

In general, lectins are used in blood typing and serology, and they are widely used in affinity chromatography for purifying ... Clavaria zollingeri contains lectins, a class of proteins that bind specific carbohydrates on the surface of cells, causing ... ISBN 978-81-85041-73-5. Jeune-Chung KH, Kim MK, Chung SR (1987). "Studies on lectins from mushrooms II. Screening of bioactive ... It was named after Swiss botanist Heinrich Zollinger, who researched the genus Clavaria, and collected the type specimen in ...

Nufer O, Mitrovic S, Hauri HP (Apr 2003). "Profile-based data base scanning for animal L-type lectins and characterization of ... "Entrez Gene: LMAN2L lectin, mannose-binding 2-like". Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace ...

... discoverer of C-type Lectins. His other son, Lee C. Drickamer is a well-known animal behaviorist and textbook author who ...

Its C-type lectin domain, EGF-like, SCR repeats, and transmembrane domains are each encoded by separate exons, whereas the E- ... E selectin has a cassette structure: an N-terminal, C-type lectin domain, an EGF (epidermal-growth-factor)-like domain, 6 Sushi ... structure reveals limited contact between the two domains and a coordination of Ca2+ not predicted from other C-type lectins. ... Each of these cell types is found in acute and chronic inflammatory sites in association with expression of E-selectin, thus ...

C-type lectins, Molecular chaperones). ... The mannose lectin Yos-9 (OS-9 in humans) marks and sorts ... The x-ray crystal structure of calnexin revealed a globular lectin domain and a long hydrophobic arm extending out. ATP and ... Otteken A, Moss B (Jan 1996). "Calreticulin interacts with newly synthesized human immunodeficiency virus type 1 envelope ... "Rer1 and calnexin regulate endoplasmic reticulum retention of a peripheral myelin protein 22 mutant that causes type 1A Charcot ...

It is a type of glycosylation.[citation needed] It is important clinically, and high levels of fucosylation have been reported ... Therefore, antibodies and lectins that are able to recognize cancer associated fucosylated oligosaccharides have been used as ...

The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially ... NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK ... 2004). "Symmetry recognizing asymmetry: analysis of the interactions between the C-type lectin-like immunoreceptor NKG2D and ... and the presence of a C-type lectin domain. ... NKG2-F type II integral membrane protein is a protein that in ...

2007). "Hemolytic C-type lectin CEL-III from sea cucumber expressed in transgenic mosquitoes impairs malaria parasite ... This lectin has the ability to block the development of Plasmodium, the causal agent of malaria, when it is expressed in ... has been researched as a possible source of bioactive molecules and has been found to contain a galactose-specific lectin with ...

The CL-K1 protein is a C-type lectin, and belongs to the collectin family of these proteins. Other than its role in innate ... The protein is a type of connectin called a mannan-binding lectin, which plays a role in innate immunity by binding to ... It is characterized by facial clefting (any type of cleft in the bones and tissues of the face, including a cleft lip and ... Both genes encode proteins of the lectin complement pathway, which plays a role in the complement system of innate, or non- ...

Future approach may target DC subsets based on their specifically expressed C-type lectin receptors or chemokine receptors. ... and targeting the DCs with antibodies to C-type lectin receptors or agonistic antibodies (e.g., anti-CD40) that are conjugated ... Dendritic cells, a type of antigen-presenting cell, are harvested from the person needing the immunotherapy. These cells are ... Anti-PD-1/PD-L1 and anti-CTLA-4 antibodies are the two types of checkpoint inhibitors currently available to patients. The ...

... belonging to the NKG2 family of C-type lectin-like receptors. NKG2D is encoded by KLRK1 (killer cell lectin like receptor K1) ... Key role in the transformation of CD8+ T cells into effector or memory types is played by mammalian target of rapamycin complex ... However, the molecular mechanisms of this type of regulation are unknown. In posttranscriptional regulation, stabilization of ... a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells". The Journal of ...