Langerhans cell histiocytosis Langerhans cell sarcoma Interdigitating dendritic cell sarcoma/tumor Follicular dendritic cell ... Langerhans cell sarcoma (LCS) is a rare form of malignant histiocytosis. It should not be confused with Langerhans cell ... Langerhans cell sarcoma can occur de novo, or can occur as a malignant transformation of Langerhans cell histiocytosis. The ... Langerhans Cell Sarcoma (LCS) is a cancerous disease caused by the uncontrolled overproliferation of Langerhans cells. Because ...

... is seen in osteosarcoma, Ewing sarcoma and Langerhans cell histiocytosis. In radiological images ...

Some types of cancers can cause it such as rhabdomyosarcoma, extrosseal Ewing sarcoma, Langerhans cell histiocytosis, ... cancer due to malignancy of mesenchymal cells that have failed to fully differentiate into muscle cells Langerhans cell ... Condition due to excess build-up of Langerhans cells. Lupus: autoimmune disease Diagnosis of the medical condition is based on ... This condition results in structural change of red blood cells (RBCs), shearing of RBCs, and anemia. Hemolytic disease of the ...

Amongst leukocytes, E-cadherin expression is unique to Langerhans cells. Langerhans cells utilize E-cadherin to localize in the ... Histiocytic sarcoma Localized histiocytic sarcoma Diffuse histiocytic sarcoma Histiocytoma is a common, benign, cutaneous ... and poorly differentiated mast cell tumors. Cutaneous histiocytoma = Langerhans cells: CD1+, CD11c+, MHCII+, CD86+, E-cad+, ... derived from specialised epidermic dendritic cells, the Langerhans cells) 2. Reactive histiocytosis (immunohistochemical ...

Langerhans cell histiocytosis (LCH) Lymphangioleiomyomatosis (LAM) Lymphocytic interstitial pneumonia (LIP) Birt-Hogg-Dubé ... This form of presentation has been described in metastatic sarcomas. A focal lung pneumatosis that is an incidental imaging ...

9.2.2 Rosai-Dorfman disease 9.2.3 Juvenile xanthogranuloma 9.2.4 Langerhans cell histiocytosis 9.2.5 Histiocytic sarcoma 10.1 ... granular cell tumor of the sellar region, and spindle cell oncocytoma 11.4 Pituitary adenoma/PitNET 11.5 Pituitary blastoma ... 9.1.2.4 T-cell and NK/T-cell lymphomas 9.2 Histiocytic tumors 9.2.1 Erdheim-Chester disease ... FET-CREB fusion-positive 7.1.4.2 CIC-rearranged sarcoma 7.1.4.3 Primary intracranial sarcoma, DICER1-mutant 7.1.4.4 Ewing ...

... sarcoma Malignant diseases of macrophages Histiocytic lymphoma A histiocytoma originates from epidermal Langerhans cells of ... Langerhans cells are dendritic cells found in the skin and function by internalizing antigens (foreign particles) and ... Ginhoux F, Tacke F, Angeli V, Bogunovic M, Loubeau M, Dai XM, Stanley ER, Randolph GJ, Merad M (2006). "Langerhans cells arise ... A similar disease in humans, Hashimoto-Pritzker disease, is also a Langerhans cell histiocytosis. Dog breeds that may be more ...

Langerhans cell histiocytosis, Langerhans cell sarcoma, lymphoma, sarcoidosis, IgG4-related disease, and tuberculosis. The ... non-Langerhans cell histiocytoses". Rosai-Dorfman disease itself was classified into "Familial", "Classical (nodal)", " ... Microscopic examination of stained specimens will show histiocytes with lymphocytes and possibly other types of cells trapped ... "Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages". Blood. 127 (22): 2672-2681. ...

Langerhans cells are dendritic cells found in the skin and function by internalizing antigens (foreign particles) and ... Affolter V, Moore P (2002). "Localized and disseminated histiocytic sarcoma of dendritic cell origin in dogs". Vet Pathol. 39 ( ... Ginhoux F, Tacke F, Angeli V, Bogunovic M, Loubeau M, Dai XM, Stanley ER, Randolph GJ, Merad M (2006). "Langerhans cells arise ... They include the following: Reactive diseases of Langerhans cells (most important feature in immune histochemistry is ...

Cell Cycle. 2013, 12(4):547-52. Chan JM, Bilodeau E, Celin S, Nikiforov Y, Johnson JT. Ewing sarcoma of the thyroid: Report of ... Yousem SA, Dacic S, Nikiforov YE, Nikiforova M. Pulmonary Langerhans Cell Histiocytosis: Profiling of Multifocal Tumors Using ... Cell. 2014 Oct 23;159(3):676-90. Nikiforov YE, Carty SE, Chiosea SI, Coyne C, Duvvuri U, Ferris RL, Gooding WE, Hodak SP, ... Homologous chromosomes move and rapidly initiate contact at the sites of double-strand breaks in genes in G0-phase human cells ...

Schwann cells, and melanocytes), chondrocytes, adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendritic cells ... paraganglioma stromal cells, histiocytoma, and clear-cell sarcomas. Further, S100 proteins are markers for inflammatory ... "Differentiation of Langerhans cells from interdigitating cells using CD1a and S-100 protein antibodies". Biotechnic & ... Wilson, AJ; Maddox, PH; Jenkins, D (January 1991). "CD1a and S100 antigen expression in skin Langerhans cells in patients with ...

... monostotic Langerhans cell histiocytosis, polystotic Langerhans cell histiocytosis, disseminated Langerhans cell sarcoma ... dendritic cell tumour Interdigitating dendritic cell sarcoma Follicular dendritic cell sarcoma Fibroblastic reticular cell ... associated lymphoproliferative disorders Histiocytic and dendritic cell neoplasms Histiocytic sarcoma Langerhans cell ... NOS Germinal centre B-cell subtype Activated B-cell subtype T-cell/histiocyte-rich large B-cell lymphoma Primary DLBCL of the ...

van den Berg LM, Geijtenbeek TB (2012). "Antiviral Immune Responses by Human Langerhans Cells and Dendritic Cells in HIV-1 ... Bénichou S, Benmerah A (2003). "[The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the ... a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells". Cell. 100 (5): 587-97. doi:10.1016/ ... On myeloid and pre-plasmacytoid dendritic cells DC-SIGN mediates dendritic cell rolling interactions with blood endothelium and ...

... clear cell adenocarcinoma - clear-cell sarcoma - clear cell sarcoma of the kidney - clinical breast exam - clinical resistance ... islet cell - islet cell cancer - islet of Langerhans cell - isoflavone - isointense - isolated hepatic perfusion - isolated ... cell - cell differentiation - cell motility - cell proliferation - cell respiration - cell adhesion - cellular adoptive ... specific immune cell - SPECT - SPF - spiculated mass - spindle cell cancer - spindle cell sarcoma - spiral CT scan - ...

... large-cell MeSH C15.604.667.400.390.550.465 - lymphoma, large-cell, ki-1 MeSH C15.604.667.400.400 - histiocytosis, langerhans- ... mast-cell sarcoma MeSH C15.604.744.293 - hypersplenism MeSH C15.604.744.428 - myeloid metaplasia MeSH C15.604.744.617 - splenic ... cell MeSH C15.604.667.400.400.360 - eosinophilic granuloma MeSH C15.604.667.400.410 - histiocytosis, non-langerhans-cell MeSH ... mantle-cell MeSH C15.604.515.569.480.475 - lymphoma, large-cell MeSH C15.604.515.569.480.475.300 - lymphoma, large-cell, ...

... lesions Non-small cell lung cancer Thyroid cancer Kidney cancer Multiple myeloma Melanoma Non-Hodgkin lymphoma Langerhans cell ... Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing sarcoma are rare; the most common bone tumor is ... Tumor cells may have paraneoplastic effects, such as via the secretion of Prostaglandin E, TGF-alpha, TGF-beta, TNF, and ... The triggers which eventually awaken metastatic tumor cells are an active field of study as they could elucidate mechanisms of ...

Due to the elevated levels of blood glucose in an individual, the β-cells (islets of Langerhans) in the pancreas must release ... polymerase turnover alterations do not contribute to PARP overexpression in Ewing's sarcoma cells". Oncology Reports. 9 (3): ... The more receptors a cell has that are tuned to the message, the more the cell will respond to it. Receptors are created, or ... This process is illustrated by the insulin receptor sites on target cells, e.g. liver cells, in a person with type 2 diabetes. ...

X M9755/3 Histiocytic sarcoma True histiocytic lymphoma M9756/3 Langerhans cell sarcoma M9757/3 Dendritic cell sarcoma, NOS ... Pleomorphic cell sarcoma M8803/3 Small cell sarcoma Round cell sarcoma M8804/3 Epithelioid sarcoma Epithelioid cell sarcoma ... NOS M9752/1 Langerhans cell histiocytosis, unifocal Langerhans cell granulomatosis, unifocal Langerhans cell histiocytosis, ... multifocal Langerhans cell histiocytosis, poly-ostotic M9754/3 Langerhans cell histiocytosis, disseminated Langerhans cell ...

Langerhans cell histiocytosis) lower (e.g., cryptogenic fibrosing alveolitis, connective tissue disease, asbestosis, drug ... sarcoma/infection/infarction/vascular Doubling time of six to 18 months: benign tumor/malignant granuloma Doubling time of more ... cystic bronchiectasis Langerhans cell histiocytosis lymphangioleiomyomatosis Ground glass extrinsic allergic alveolitis ... Langerhans cell histiocytosis, lymphangioleiomyomatosis, cystic fibrosis, allergic bronchopulmonary aspergillosis) decreased (e ...

The epidermis contains four cell types: keratinocytes, melanocytes, Langerhans cells, and Merkel cells. Of these, keratinocytes ... Diffuse large B-cell lymphoma (primary cutaneous large B-cell lymphoma) Granulocytic sarcoma (chloroma, myeloid sarcoma) ... pale cell acanthoma) Clear cell squamous cell carcinoma (clear cell carcinoma of the skin) Chronic scar keratosis (chronic ... Solitary trichoepithelioma Spindle cell squamous cell carcinoma (spindle cell carcinoma) Spiradenoma Squamous cell carcinoma ...

"Cloning of a cDNA encoding rat bone marrow stromal cell antigen 1 (BST-1) from the islets of Langerhans". Gene. 165 (2): 329- ... "Molecular mechanism of BST2/tetherin downregulation by K5/MIR2 of Kaposi's sarcoma-associated herpesvirus". Journal of Virology ... plasma cells and plasmacytoid dendritic cells, and in many other cells, it is only expressed as a response to stimuli from IFN ... May 2020). "B Cell Tetherin: A Flow Cytometric Cell-Specific Assay for Response to Type I Interferon Predicts Clinical Features ...

2020), who consider Langerhans cell histiocytosis to be the most likely diagnosis, making it the first case of LCH recognized ... who interpret their findings as evidence of these sauropods being affected by pathologies similar to Ewing's sarcoma and avian ... Bruce M. Rothschild; Darren Tanke; Frank Rühli; Ariel Pokhojaev; Hila May (2020). "Suggested case of Langerhans Cell ... Cell Research. 30 (8): 693-701. doi:10.1038/s41422-020-0349-y. PMC 7395088. PMID 32581344. Gerald Mayr; Thomas Lechner; ...

CSF1R signaling is necessary for differentiation of microglia and Langerhans cells which are derived from yolk sac progenitor ... sarcoma, and leukemias. In 2019, Pexidartinib was FDA-approved for treatment of diffuse-type tenosynovial giant cell tumors, a ... CSF1R signaling has been found to play important roles in non-myeloid cells such as neural progenitor cells, multipotent cells ... Hematopoietic stem cells express CSF1R at low levels, but CSF1R is highly expressed in more differentiated myeloid cell types ...

Paul Langerhans (1847-1888), German pathologist, physiologist and biologist. William Boog Leishman (1865-1926), English ... Max Askanazy (1865-1940), German pathologist (see Askanazy cell). E. Ask-Upmark, 20th-century Swedish pathologist (see Ask- ... eponymist of Ewing's sarcoma, one of the founders of AACR. Robert (Robin) Sanno Fåhræus (1888-1968), Swedish pathologist (see ... see Sarcoma). William Henry Welch (1850-1934), American physician, pathologist, bacteriologist, medical school administrator, ...

He detected HHV8 virus in classical Kaposi's sarcoma and Merkel cell polyomavirus in Merkel-cell carcinoma. European ... BRAFV600E mutation in cutaneous lesions of patients with adult Langerhans cell histiocytosis, JOURNAL OF THE EUROPEAN ACADEMY ... Committee supervising the research and terapeutic use of embrionyc and tissue stem cells" Medical Sciences Section of the ... chemokines and human beta-defensin-2 in vaginal epithelial cells, MICROBES AND INFECTION 7: (9-10) pp. 1117-1127, 2005. Nagy I ...

1989). "T-cell response to purified protein derivative after removal of Langerhans' cells from epidermal cell suspensions ... Bénichou S, Benmerah A (2003). "The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the ... Antigen-presenting cells (macrophages, B-cells and dendritic cells) are the cells in which DR are typically found. Increased ... These cells then bind to antigens on the surface of B-cells stimulating B-cell proliferation. The primary function of HLA-DR is ...

1989). "T-cell response to purified protein derivative after removal of Langerhans' cells from epidermal cell suspensions ... The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the endocytosis pathway]". Med Sci (Paris). ... Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha ... Cell. Biol. 12 (12): 5610-9. doi:10.1128/MCB.12.12.5610. PMC 360500. PMID 1448091. Schaiff WT, Hruska KA, McCourt DW, et al. ( ...

... and malignant cells of bone and soft tissue sarcomas. FAP is thought to be involved in the control of fibroblast growth or ... of the homologous proteases fibroblast activation protein and dipeptidyl peptidase-IV in the adult human Langerhans islets". ... and in adults in pancreatic alpha cells in multipotent bone marrow stromal cells (BM-MSC) and uterine stroma. FAP expression is ... Fassnacht M, Lee J, Milazzo C, Boczkowski D, Su Z, Nair S, Gilboa E (August 2005). "Induction of CD4(+) and CD8(+) T-cell ...

... subsequent research revealed that other cells (such as keratinocytes, fibroblasts and epithelial Langerhans cells) could also ... The SV40 promoter was conventionally used until research showed that vectors driven by the Rous Sarcoma Virus (RSV) promoter ... The type of T-cell help raised is determined by the differentiated state of antigen presenting cells. Dendritic cells can ... which include dendritic cells, macrophages and specialised B-cells called professional antigen presenting cells (APC). After ...

... of Langerhans cell histiocytosis patients. The V600E mutation is a likely driver mutation in 100% of cases of hairy cell ... The gene is also referred to as proto-oncogene B-Raf and v-Raf murine sarcoma viral oncogene homolog B, while the protein is ... The B-Raf protein is involved in sending signals inside cells which are involved in directing cell growth. In 2002, it was ... "Recent advances in the understanding of Langerhans cell histiocytosis". British Journal of Haematology. 156 (2): 163-172. doi: ...