Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; ...

... laminin-2 (alpha2-beta1-gamma1) and laminin-4 (alpha2-beta2-gamma1). Alpha-7/beta-1 is the major integrin complex expressed in ... Collo G, Starr L, Quaranta V (September 1993). "A new isoform of the laminin receptor integrin alpha 7 beta 1 is ... Kramer RH, Vu MP, Cheng YF, Ramos DM, Timpl R, Waleh N (1992). "Laminin-binding integrin alpha 7 beta 1: functional ... Ziober BL, Chen Y, Kramer RH (1997). "The laminin-binding activity of the alpha 7 integrin receptor is defined by ...

... and laminin. β1- integrin is expressed on the surface of SSCs and is involved in their adhesion to the laminin component of the ... These structures are rich in laminin, collagen and heparan sulfate proteoglycans. Other ECM molecules, such as tenascin-C, MMPs ... that are localized into discrete clusters within a ColIV and laminin extracellular matrix (ECM). ColI and fibronectin are ...

Mannose has recently been reported in a vertebrate, the mouse, Mus musculus, on the cell-surface laminin receptor alpha ... "O-Mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding". Science. 327 (5961): 88-92. Bibcode:2010Sci ...

... binds several proteins, including vinculin, DES, actin., fodrin, microtubule-associating proteins, nuclear laminin B., ...

Mice lacking laminin alpha2-subunit produced fewer OPCs in the SVZ. Deletion of Dicer1 disrupts normal brain myelination. ... Laminin, a component of the extracellular matrix, plays an important role regulating oligodendrocyte production. ... Relucio J, Menezes MJ, Miyagoe-Suzuki Y, Takeda S, Colognato H (October 2012). "Laminin regulates postnatal oligodendrocyte ...

It has been shown to interact with laminin 5 and fibronectin, as well as collagen IV, by binding these proteins in the NC-1 ... Rousselle P, Keene DR, Ruggiero F, Champliaud MF, Rest M, Burgeson RE (August 1997). "Laminin 5 binds the NC-1 domain of type ... It has been shown that interactions between the NC-1 domain of collagen VII and several other proteins, including laminin-5 and ...

The laminin-like globular domain contains the active motif of endorepellin, and is unable to be cleaved by cells expressing ... Domain III has homology to the domain IVa and IVb of laminin. Domain IV consists of a series of IG modules. The structure of ... Perlecan expression and thus basement membrane maturation is dependent on nidogen crosslinking of collagen IV and laminin γ1 ... Perlecan and laminin-1 appear to be important in this guidance pathway, although perlecan induction occurs slightly later than ...

Netrin-5 is included in the family of secreted laminin-related proteins. Netrin-5 functions are not fully clarified. However, ...

They are also known to interact with laminin, fibronectin, tenascin, and collagen. CSPGs are generally secreted from cells. ...

As another example, cleavage of laminin-5, a component of the basement membrane, by MMP-2 has been shown to reveal a cryptic ... "Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5". Science. 277 (5323): 225-28. doi:10.1126/ ...

This is performed via selective interaction of the dendrimer with laminin receptors. Peptide dendrimers may be employed in the ...

... such as laminin, or drug eluting substances. The nature of dissociated neuronal networks does not seem to change or diminish ... "Nanoscale laminin coating modulates cortical scarring response around implanted silicon microelectrode arrays". Journal of ...

... an epithelial integrin that binds laminin in the sea urchin embryo". Developmental Biology. 207 (1): 1-13. doi:10.1006/dbio. ...

Farwell AP, Dubord-Tomasetti SA (September 1999). "Thyroid hormone regulates the expression of laminin in the developing rat ...

This gene has been referred to as 'laminin receptor homolog' because a chimeric transcript consisting of sequence from this ... gene and sequence from the laminin receptor gene was isolated; however, it is not believed that this gene encodes a laminin ... cloning and genomic analysis of a new multigene family sharing common phylogenetic and expression profiles with the laminin ...

However, expression of laminin 332 has been detected in malignant cells, and laminin 332 appears to be capable of promoting ... The major basement membrane zone proteins identified include : C-terminus of BP180 BP230 Laminin 332(also known as laminin 5 or ... Malignancy - MMP with antibodies directed against laminin 332 (previously known as laminin 5 and epiligrin) has been associated ... Since diagnostic laboratory testing for laminin 332 antibodies is not commercially available, suspicion for laminin 332 ...

1984). "Immunolocalization of collagen types, laminin and fibronectin in the normal human pancreas". Digestion. 30 (3): 158-64 ... laminin binding protein". Cell Adhes. Commun. 2 (3): 185-93. doi:10.3109/15419069409004436. PMID 7827955. Ständer M, Naumann U ...

In addition, her studies have found that netrin-1, DCC, and laminin-1 are key players in axon guidance from the retina. For ... "Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1". Nature. 401 (6748): 69-73. Bibcode:1999Natur.401... ...

E2 is encoded in introns in the gene for a laminin-binding protein. This family also contains the related ACA6, M2 and MBI-136 ... Selvamurugan N, Eliceiri GL (November 1995). "The gene for human E2 small nucleolar RNA resides in an intron of a laminin- ...

The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to ... The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Neurexins are presynaptic ... synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin". Science. 257 (5066): 50-56. Bibcode: ...

The lamina lucida layer is made up of laminin, integrins, entactins, and dystroglycans. Integrins are a key component of ... Kubota Y, Kleinman HK, Martin GR, Lawley TJ (October 1988). "Role of laminin and basement membrane in the morphological ... reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule". ... Basement membrane Basal lamina Lamina lucida laminin integrins (hemidesmosomes) nidogens dystroglycans Lamina densa collagen IV ...

1999). "Decreased expression of laminin beta 1 in chromosome 21-linked Bethlem myopathy". Neuromuscul. Disord. 9 (5): 326-9. ...

"Formation of the zebrafish midbrain-hindbrain boundary constriction requires laminin-dependent basal constriction". Mechanisms ...

... laminin-5), entactin/nidongen or the perlecan. on the extracellular surface of the hemidesmosome, laminin-5 molecules form ... Mutation of the genes encoding laminin-5 chains results in junctional epidermolysis bullosa. Junctional epidermolysis bullosa ... 557 JEB-H is generally caused by mutations in one of the three laminin-332 coding genes: LAMA3 (18q11.2), LAMB3 (1q32) and ... chains its extracellular domain enters the basal lamina and interacts with type IV collagen suprastructure containing laminins ...

1984). "Immunolocalization of collagen types, laminin and fibronectin in the normal human pancreas". Digestion. 30 (3): 158-64 ... laminin, and fibronectin". Gut. 21 (1): 63-71. doi:10.1136/gut.21.1.63. PMC 1419572. PMID 6988303. v t e (Articles with short ...

Laminin receptor is also a target for PEDF, and the interaction occurs between residues 24-57 of PEDF, a region known to ... Bernard A, Gao-Li J, Franco CA, Bouceba T, Huet A, Li Z (Apr 2009). "Laminin receptor involvement in the anti-angiogenic ...

The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to ... The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. GRCh38: Ensembl release 89 ... synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin". Science. 257 (5066): 50-56. Bibcode: ...

Aumailley M, Wiedemann H, Mann K, Timpl R (September 1989). "Binding of nidogen and the laminin-nidogen complex to basement ... Hinek A (July 1994). "Nature and the multiple functions of the 67-kD elastin-/laminin binding protein". Cell Adhesion and ...

The RGC will then extend an axon in the retinal ganglion cell layer, which is directed by laminin contact. The retraction of ... "The oriented emergence of axons from retinal ganglion cells is directed by laminin contact in vivo". Neuron. 70 (2): 266-80. ... "Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1". Nature. 401 (6748): 69-73. Bibcode:1999Natur.401... ...