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*  Ketone bodies
In the brain, ketone bodies are also used to make acetyl-CoA into long-chain fatty acids. Ketone bodies are produced by the ... Ketone bodies Ketone bodies are three water-soluble molecules (acetoacetate, beta-hydroxybutyrate, and their spontaneous ... The ketone bodies are released by the liver into the blood. All cells with mitochondria can take ketone bodies up from the ... to be converted into ketone bodies. The resulting very high levels of ketone bodies lower the pH of the blood plasma which ...
*  Diabetic ketoacidosis
The ketone bodies, however, have a low pKa and therefore turn the blood acidic (metabolic acidosis). The body initially buffers ... Ketones can be measured in the urine (acetoacetate) and blood (β-hydroxybutyrate). When compared with urine acetoacetate ... DKA results from a shortage of insulin; in response the body switches to burning fatty acids which produces acidic ketone ... Diabetic ketoacidosis may be diagnosed when the combination of hyperglycemia (high blood sugars), ketones in the blood or on ...
*  Ketonuria
Urine ketones appear before there is any significant increase in blood ketones; therefore, urine ketone measurement is ... Higher levels of ketones in the urine indicate that the body is using fat as the major source of energy. Ketone bodies that ... Ketones are metabolic end-products of fatty acid metabolism. In healthy individuals, ketones are formed in the liver and are ... BMJ Student Archive-Glycosuria and Ketonuria Ketone Testing-Barbara Davis Center for Diabetes Measuring Ketones in Urine- ...
*  Succinyl-CoA:3-oxoacid CoA transferase deficiency
They experience attacks of ketoacidosis during illness, and even when unwell may have elevated levels of ketone bodies in blood ... Succinyl-CoA:3-oxoacid CoA transferase deficiency (SCOT deficiency) is an inborn error of ketone body utilization. Succinyl-CoA ... Fukao, Toshiyuki; Mitchell, Grant; Sass, Jörn Oliver; Hori, Tomohiro; Orii, Kenji; Aoyama, Yuka (8 April 2014). "Ketone body ...
*  Aldose
However aldehydes and ketones are almost always more stable than the corresponding enol forms, so the aldo- and keto- forms ... and are therefore ketones. Like most carbohydrates, simple aldoses have the general chemical formula Cn(H2O)n. Because ...
*  2,3-Wittig rearrangement
The scope and limitation of the sigmatropic sequences as a synthetic method for δ,ε-unsaturated ketones". Chem. Lett. (9): 1349 ...
*  Ketogenesis
Additionally, ketone bodies can be anti-inflammatory. Some kinds of cancer cells are unable to use ketone bodies, as they do ... The result is a rate of ketone production higher than the rate of ketone disposal, and a decrease in blood pH. There are some ... ACoA and thereby produce ketones. Besides its role in the synthesis of ketone bodies, HMG-CoA is also an intermediate in the ... The production of ketone bodies is then initiated to make available energy that is stored as fatty acids. Fatty acids are ...
*  Chiral auxiliary
Condensation of SAMP or RAMP with an aldehyde or ketone affords the (E)-hydrazine. Deprotonation with lithium diisopropylamide ... Condensation of tert-butanesulfinamide with aldehydes and ketones Addition of a Grignard reagent to a tert-butanesulfinyl ... and Ketones". J. Am. Chem. Soc. 119: 6496-6511. doi:10.1021/ja970402f. Kummer, D. A.; Chain, W. J.; Morales, M. R.; Quiroga, O ... and Ketones". J. Am. Chem. Soc. 119: 6496-6511. doi:10.1021/ja970402f. Myers, A. G.; Morales, M. R.; Mellem, K. T. (2012). " ...
*  Enantioselective reduction of ketones
Enantioselective ketone reductions convert prochiral ketones into chiral, non-racemic alcohols and are used heavily for the ... The ketone typically occupies the more open regions of space, leading to hydride delivery to a single face of the ketone. The ... Transfer hydrogenation to ketones leads to alcohols (the Meerwein-Ponndorf-Verley reduction), and in the presence of a chiral ... Ketones with a chelating group undergo enantioselective reduction in the presence of a chiral Ru(BINAP) catalyst. The ...
*  Ketone
Exceptions to this rule are the unsaturated ketones such as methyl vinyl ketone with LD50 of 7 mg/kg (oral). Diketone Ketone ... Ketones are trigonal planar around the ketonic carbon, with C−C−O and C−C−C bond angles of approximately 120°. Ketones differ ... The word ketone is derived from Aketon, an old German word for acetone. According to the rules of IUPAC nomenclature, ketones ... This equilibrium allows ketones to be prepared via the hydration of alkynes. Ketones are far more acidic (pKa ≈ 20) than a ...
*  Raspberry ketone
... is a natural phenolic compound that is the primary aroma compound of red raspberries. Raspberry ketone occurs ... "Raspberry Ketones for Weight Loss". About.com. Canberra, Jules. "What's All The Hype About Raspberry Ketone?". Authority Health ... This two-step method produces raspberry ketone in 99% yield. Raspberry ketone is sometimes used in perfumery, in cosmetics, and ... "Raspberry Ketone". WebMD. Bredsdorff L, Wedebye EB, Nikolov NG, Hallas-Møller T, Pilegaard K (2015). "Raspberry ketone in food ...
*  Perilla ketone
... is a natural terpenoid that consists of a furan ring with a six-carbon side chain containing a ketone functional ... The ketone was identified in 1943 by Sebe as the main component of the essential oil of Perilla frutescens. Perilla ketone is ... Perilla ketone (3-Furyl isoamyl ketone) has been prepared in 74% yield via the Stille reaction from a 3-furyl-organotin ... Perilla ketone was synthesized in 1957 by Matsuura from 3-furoyl chloride and an organocadmium compound similar to the Gilman ...
*  Reductive dehalogenation of halo ketones
... geminal dihalo ketones may be reduced to the parent ketone, monohalo ketone, or functionalized monohalo ketone with ... The α-halo ketones are readily prepared from ketones by various ketone halogenation reactions, and the products are reactive ... 5) Reductions of α-halo ketones may afford the parent ketones, partially reduced halo ketones, or products arising from ... β-unsaturated ketone. (9) Organocuprates may also be employed for the reduction of α,α'-dihalo ketones to alkylated ketones. In ...
*  Michler's ketone
... is an organic compound with the formula of [(CH3)2NC6H4]2CO. This electron-rich derivative of benzophenone is ... Condensation of Michler's ketone with N-phenyl-1-naphthylamine gives the dye Victoria Blue B (CAS#2580-56-5, CI Basic Blue 26 ... Michler's ketone is commonly used as an additive in dyes and pigments as a sensitizer for photoreactions because of its ... The ketone is prepared today as it was originally by Michler using the Friedel-Crafts acylation of dimethylaniline (C6H5NMe2) ...
*  Dibenzyl ketone
Vera Bogdanovskaia is credited with the classification of dibenzyl ketone. Phenylacetone self condenses to form dibenzyl ketone ... Dibenzyl ketone, or 1,3-diphenylacetone, is an organic compound composed of two benzyl groups attached to a central carbonyl ... For this reason, dibenzyl ketone is frequently used in an aldol condensation reaction with benzil (a dicarbonyl) and base to ... carbon dioxide is still being evolved when distillation is stopped the resultant liquid is a mixture of dibenzyl ketone and ...
*  Ketone halogenation
In the case of methyl ketones, this reaction often occurs a third time to form a ketone trihalide, which can undergo rapid ... In organic chemistry ketone halogenation is a special type of halogenation. The reaction may be carried out under either acidic ... The position alpha to the carbonyl group in a ketone is easily halogenated, due to the ability to form an enolate in basic ... functionality can be installed selectively in the alpha position of a ketone. ...
*  Hydroxy ketone
In organic chemistry a hydroxy ketone (often referred to simply as a ketol) is a functional group consisting of a ketone ... a beta-hydroxy ketone, RCR′(OH)CR2(CO)R). An α-hydroxy ketone can consist of either a primary alcohol (e.g. hydroxyacetone) or ... In the two main classes, the hydroxyl group can be placed in the alpha position (an alpha-hydroxy ketone RCR′(OH)(CO)R) or in ... a secondary alcohol; the latter are often broadly referred to as acyloins Prominent β-hydroxy ketones are aldol adducts. IUPAC ...
*  Ketone enolate
A ketone enolate is an enolate formed from a ketone by reaction with a strong base, such as lithium diisopropylamide, or with a ... In the latter case, the base takes the hydrogen ion from the alpha carbon of the ketone and the electron acceptor atom of the ... Lewis acid becomes attached to the oxygen of the ketone.. ...
*  Oxidation of secondary alcohols to ketones
This leaves a ketone, as R1-COR2. Ketones cannot normally be oxidised any further because this would involve breaking a C-C ... PCC, when used in an organic solvent, can be used to oxidise a secondary alcohol into a ketone. It has the advantage of doing ... When a secondary alcohol is oxidised, it is converted to a ketone. The hydrogen from the hydroxyl group is lost along with the ... The Dess-Martin periodinane is a mild oxidant for the conversion of alcohols to aldehydes or ketones. The reaction is performed ...
*  Methyl isobutyl ketone
Diisobutyl ketone (DIBK), a related lipophilic ketone, is also used for this purpose. Methyl isobutyl ketone is also used as a ... Methyl isobutyl ketone (MIBK) is the organic compound with the formula (CH3)2CHCH2C(O)CH3. This colourless liquid, a ketone, is ... Methyl isobutyl ketone is made from acetone via a three-step process. Firstly acetone undergoes an aldol reaction to give ... "Methyl Isobutyl Ketone" (PDF). Retrieved 13 December 2015. Hans-Wilhelm Engels et al., "Rubber, 4. Chemicals and Additives" in ...
*  Weinreb ketone synthesis
The Weinreb-Nahm ketone synthesis is a chemical reaction used in organic chemistry to make carbon-carbon bonds. It was ... N,O-Dimethylhydroxylamine Ketone Synthesis Nahm, S.; Weinreb, S. M. (1981), "N-methoxy-n-methylamides as effective acylating ... Synthesis of unsymmetrical ketones", The Journal of Organic Chemistry, 56: 2911, doi:10.1021/jo00008a057 Sibi, M. P.; Sharma, R ... For these latter reactions, two equivalents of the incoming group add to form an alcohol rather than a ketone or aldehyde. This ...
*  Arachidonyl trifluoromethyl ketone
... (ATK) is an analog of arachidonic acid. that inhibits some isoforms of the enzyme ... Vana, Adam C.; Li, Shihe; Ribeiro, Rachel; Tchantchou, Flaubert; Zhang, Yumin (2011). "Arachidonyl trifluoromethyl ketone ... "Arachidonyl trifluoromethyl ketone is neuroprotective after spinal cord injury". Journal of Neurotrauma: 110306202455053. doi: ... "Oral administration of cytosolic PLA2 inhibitor arachidonyl trifluoromethyl ketone ameliorates cauda equina compression injury ...
*  Wieland-Miescher ketone
The Wieland-Miescher ketone is a racemic bicyclic diketone (enedione) and is a versatile synthon which has so far been employed ... Wieland-Miescher ketone contains the AB-ring structure of steroids and is for this reason an attractive starting material for ... The original Wieland-Miescher ketone is racemic and prepared in a Robinson annulation of 2-methyl-1,3-cyclohexanedione and ... Most advances in total synthesis methods starting from Wieland-Miescher ketone were fueled by the search for alternative ...
*  Methylethyl ketone oxime
... is the organic compound with the formula C2H5C(NOH)CH3. This colourless liquid is the oxime derivative ... of methyl ethyl ketone. MEKO, as it is called in the paint industry, is used to suppress "skinning" of paints: the formation of ...
*  Blaise ketone synthesis
... tert-Butyl Phenyl Ketone". Org. Synth. 55: 122. ; Coll. Vol., 6, p. 248 ^ Fujisawa, T.; Sato, T. (1988). "Ketones from ... The Blaise ketone synthesis (named after Edmond E. Blaise) is the chemical reaction of acid chlorides with organozinc compounds ... Vol., 8, p. 441 ^ Cason, J. (1947). "The Use of Organocadmium Reagents for the Preparation of Ketones". Chem. Rev. 40 (1): 17. ... 9: 1. Missing or empty ,title= (help) ^ Posner, G. H.; Whitten, C. E. (1976). "Secondary and Tertiary Alkyl Ketones from ...