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*  Late protein
L2 from HPV types 11 and 16 was shown to interact with karyopherins Kapbeta(2) and Kapbeta(3). L2 capsid proteins can also ... L1 capsid proteins can bind via its nuclear localisation signal (NLS) to karyopherins Kapbeta(2) and Kapbeta(3) and inhibit the ... L2 uses its NLSs to interact with a network of karyopherins in order to enter the nucleus via several import pathways. ...
*  Importin
... : IPO4, IPO5, IPO7, IPO8, IPO9, IPO11, IPO13 Karyopherin-α: KPNA1, KPNA2, KPNA3, KPNA4, KPNA5, KPNA6 Karyopherin-β: ... Importin-β is the typical structure of a larger superfamily of karyopherins. The basis of their structure is 18-20 tandem ... CAS (cellular apoptosis susceptibility protein) is part of the importin-β superfamily of karyopherins and is defined as a ... Importin is a type of karyopherin that transports protein molecules into the nucleus by binding to specific recognition ...
*  Nuclear localization sequence
A protein translated with a NLS will bind strongly to importin (aka karyopherin), and, together, the complex will move through ... also known as transportin or karyopherin β2), which then translocates the cargo protein into the nucleus. The structural basis ... "Rules for nuclear localisation sequence recognition by karyopherin beta 2". Cell. 126 (3): 543-58. doi:10.1016/j.cell.2006.05. ... "Crystallographic analysis of the recognition of a nuclear localisation signal by the nuclear import factor karyopherin alpha". ...
*  Transportin 1
The classical karyopherin receptor complex, such as the complex that uses Importin-β1 (encoded by gene KPNB1), is a heterodimer ... Moroianu J, Hijikata M, Blobel G, Radu A (1995). "Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or ... Bonifaci N, Moroianu J, Radu A, Blobel G (Jun 1997). "Karyopherin beta2 mediates nuclear import of a mRNA binding protein". ... Shamsher MK, Ploski J, Radu A (October 2002). "Karyopherin beta 2B participates in mRNA export from the nucleus". Proc. Natl. ...
*  Nucleoporin
Karyopherins will bind to their cargo, and reversibly interact with the FG-repeats in nucleoporins. Karyopherins and their ... Karyopherins can serve as an importin (transporting proteins into the nucleus) or an exportin (transporting proteins out of the ... Ran will bind to either GTP or GDP and has the ability to change a karyopherin's affinity for its cargo. Inside the nucleus, ... RanGTP can also bind to exportin karyopherins and pass through the nuclear pore. Once it has reached the cytosol, RanGTP can be ...
*  Karyopherin
Most proteins require karyopherins to traverse the nuclear pore. Karyopherins can act as importins (i.e. helping proteins get ... Karyopherins at the US National Library of Medicine Medical Subject Headings (MeSH) Illustrations at berkeley.edu Karyopherin ... Karyopherins are a group of proteins involved in transporting molecules between the cytoplasm and the nucleus of a eukaryotic ... Upon stress, several karyopherins stop shuttling between the nucleus and the cytoplasm and are sequestered in stress granules, ...
*  Karyopherin alpha 1
"Previously identified protein of uncertain function is karyopherin alpha and together with karyopherin beta docks import ... Karyopherin alpha 1 has been shown to interact with KPNB1 and UBR5. GRCh38: Ensembl release 89: ENSG00000114030 - Ensembl, May ... Moroianu J, Hijikata M, Blobel G, Radu A (1995). "Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or ... 1996). "Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import". J. Virol. 70 (2): 1027-32. PMC ...
*  Karyopherin alpha 2
"Entrez Gene: KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)". Lin CY, Huang PH, Liao WL, Cheng HJ, Huang CF, Kuo JC ... KPNA2 also may play a role in V(D)J recombination Karyopherin alpha 2 has been shown to interact with: ARL4A ITK, KPNB1, PLAG1 ... Braem CV, Kas K, Meyen E, Debiec-Rychter M, Van De Ven WJ, Voz ML (May 2002). "Identification of a karyopherin alpha 2 ... Proteins involved in the first step of nuclear import are members of the alpha importin family of karyopherins such as importin ...
*  IPO5
Chook YM, Blobel G (2002). "Karyopherins and nuclear import". Curr. Opin. Struct. Biol. 11 (6): 703-15. doi:10.1016/S0959-440X( ... a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in ... "Cloning and characterization of human karyopherin beta3". Proc Natl Acad Sci U S A. 94 (9): 4451-6. doi:10.1073/pnas.94.9.4451 ... "HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway". Proc. Natl. ...
*  KPNA6
"Entrez Gene: KPNA6 karyopherin alpha 6 (importin alpha 7)". Bukrinsky MI, Haffar OK (2004). "HIV-1 nuclear import: in search of ... Chook YM, Blobel G (2002). "Karyopherins and nuclear import". Curr. Opin. Struct. Biol. 11 (6): 703-15. doi:10.1016/S0959-440X( ... 1996). "Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import". J. Virol. 70 (2): 1027-32. PMC ... a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in ...
*  KPNB1
... has been shown to interact with: KPNA3, Karyopherin alpha 1, Karyopherin alpha 2, Mothers against decapentaplegic homolog ... "Entrez Gene: KPNB1 karyopherin (importin) beta 1". Köhler M, Speck C, Christiansen M, Bischoff FR, Prehn S, Haller H, Görlich D ... Each of these subunits are part of the karyopherin family of proteins. Importin alpha binds the NLS-containing cargo in the ... Bonifaci N, Moroianu J, Radu A, Blobel G (May 1997). "Karyopherin beta2 mediates nuclear import of a mRNA binding protein". ...
*  Nucleoporin 214
Bonifaci N, Moroianu J, Radu A, Blobel G (May 1997). "Karyopherin beta2 mediates nuclear import of a mRNA binding protein". ... Yaseen NR, Blobel G (Apr 1997). "Cloning and characterization of human karyopherin beta3". Proceedings of the National Academy ...
*  TMCO6
The SRP1 domain is Karyopherin(importin) alpha. This is involved in the exchange of molecules from the nucleus and the ... The exchange involves the active transport by a carrier protein called karyopherins. A di-leucine motif is also abundant in ... The SRP1 domain encodes alpha-Karyopherin (importin) and is known for intracellular trafficking and secretion on the membrane. ...
*  Nucleoporin 62
Karyopherin beta2 (transportin), a riboprotein transporter also interacts with p62. P62 also interacts with Nup93, and when ... Yaseen NR, Blobel G (1997). "Cloning and characterization of human karyopherin β3". Proc. Natl. Acad. Sci. U.S.A. 94 (9): 4451- ... Yaseen NR, Blobel G (1997). "Cloning and characterization of human karyopherin β3". Proc. Natl. Acad. Sci. U.S.A. 94 (9): 4451- ...
*  60S ribosomal protein L13
Yaseen NR, Blobel G (1997). "Cloning and characterization of human karyopherin beta3". Proc. Natl. Acad. Sci. U.S.A. 94 (9): ...
*  Nucleoporin 153
It also acts as the docking site of an importing karyopherin. On the cytoplasmic side of the NPC, Nup358 fulfills an analogous ... Yaseen NR, Blobel G (1997). "Cloning and characterization of human karyopherin beta3". Proc. Natl. Acad. Sci. U.S.A. 94 (9): ... Brownawell AM, Macara IG (2002). "Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding ... "RanGTP-mediated nuclear export of karyopherin alpha involves its interaction with the nucleoporin Nup153". Proc. Natl. Acad. ...
*  NUP98
Bonifaci N, Moroianu J, Radu A, Blobel G (May 1997). "Karyopherin beta2 mediates nuclear import of a mRNA binding protein". ... Yaseen NR, Blobel G (1997). "Cloning and characterization of human karyopherin beta3". Proc. Natl. Acad. Sci. U.S.A. 94 (9): ... Bonifaci N, Moroianu J, Radu A, Blobel G (1997). "Karyopherin beta2 mediates nuclear import of a mRNA binding protein". Proc. ... Moroianu J, Blobel G, Radu A (September 1997). "RanGTP-mediated nuclear export of karyopherin alpha involves its interaction ...
*  Importin α
Moroianu, J; Blobel, G; Radu, A (1996-06-25). "The binding site of karyopherin alpha for karyopherin beta overlaps with a ... "Previously identified protein of uncertain function is karyopherin alpha and together with karyopherin beta docks import ... Importin alpha, or karyopherin alpha refers to a class of adaptor proteins that are involved in the import of proteins into the ... They are a sub-family of karyopherin proteins. Importin α is known to bind to the nuclear localization signal (NLS) sequence of ...
*  Cell nucleus
Those karyopherins that mediate movement into the nucleus are also called importins, whereas those that mediate movement out of ... Most karyopherins interact directly with their cargo, although some use adaptor proteins. Steroid hormones such as cortisol and ... macromolecules such as RNA and proteins require association karyopherins called importins to enter the nucleus and exportins to ... DNAs are transported through the pore complexes in a process mediated by a family of transport factors known as karyopherins. ...
*  KPNA3
"Entrez Gene: KPNA3 karyopherin alpha 3 (importin alpha 4)". Köhler, M; Speck C; Christiansen M; Bischoff F R; Prehn S; Haller H ... The similarities among these proteins suggests that karyopherin alpha-3 may be involved in the nuclear transport system. KPNA3 ... 1996). "Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import". J. Virol. 70 (2): 1027-32. PMC ... "Isolation and mapping of karyopherin alpha 3 (KPNA3), a human gene that is highly homologous to genes encoding Xenopus importin ...
*  KPNA4
"Entrez Gene: KPNA4 karyopherin alpha 4 (importin alpha 3)". Liu L, McBride KM, Reich NC (Jun 2005). "STAT3 nuclear import is ... Gallay P, Stitt V, Mundy C, Oettinger M, Trono D (Feb 1996). "Role of the karyopherin pathway in human immunodeficiency virus ... Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore ... "HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway". Proceedings of ...
*  KPNA5
"Entrez Gene: KPNA5 karyopherin alpha 5 (importin alpha 6)". Bukrinsky MI, Haffar OK (2004). "HIV-1 nuclear import: in search of ... 1996). "Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import". J. Virol. 70 (2): 1027-32. PMC ... "HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway". Proc. Natl. ...
*  Inner nuclear membrane protein
King, Megan C.; Patrick Lusk, C.; Blobel, Günter (2006). "Karyopherin-mediated import of integral inner nuclear membrane ...
*  ARL4A
... has been shown to interact with Karyopherin alpha 2. GRCh38: Ensembl release 89: ENSG00000122644 - Ensembl, May 2017 ...
*  NXF1
CS1 maint: Multiple names: authors list (link) Shamsher, Monee K; Ploski Jonathan; Radu Aurelian (October 2002). "Karyopherin ...