Doi O, Ogura M, Tanaka N, Umezawa H (Sep 1968). "Inactivation of kanamycin, neomycin, and streptomycin by enzymes obtained in ... Antibiotics, such as the aminoglycosides kanamycin or neomycin, are added to the cultures during growth phases in order to ... The systematic name of this enzyme class is ATP:kanamycin 3'-O-phosphotransferase. This enzyme is also called neomycin- ... Gray GS, Fitch WM (1983). "Evolution of antibiotic resistance genes: the DNA sequence of a kanamycin resistance gene from ...

In molecular biology, kanamycin nucleotidyltransferase EC 2.7.7.- (KNTase) is an enzyme which is involved in conferring ... It catalyses the transfer of a nucleoside monophosphate group from a nucleotide to kanamycin. This enzyme is dimeric with each ... "Structural investigation of the antibiotic and ATP-binding sites in kanamycin nucleotidyltransferase". Biochemistry. 34 (41): ...

... including kanamycin B, kanamycin C, kanamycin D and kanamycin X.[citation needed] The kanamycin biosynthetic pathway can be ... Kanamycin is a mixture of three main components: kanamycin A, B, and C. Kanamycin A is the major component in kanamycin. The ... One of the branches forms kanamycin C and kanamycin B, while the other branch forms kanamycin D and kanamycin X. However, both ... kanamycin B and kanamycin D can be converted to kanamycin A, so both branches of the pathway converge at kanamycin A. Kanamycin ...

Kanamycin requires close clinical supervision because of its potential toxicity and adverse side effects to the auditory and ... "Kanamycin". Musk, Philip (2004). "Magic Shotgun Methods for Developing Drugs for CNS Disorders". Discovery Medicine. 4 (23): ... Kanamycin is an aminoglycoside antibiotic which induces deafness through blockage of the outer hair cells of the cochlea; yet ...

Resistance to amikacin also confers resistance to kanamycin and capreomycin. Resistance to amikacin and kanamycin in ... Amikacin is derived from kanamycin A: While amikacin is only FDA-approved for use in dogs and for intrauterine infection in ... This is accomplished by the L-hydroxyaminobuteroyl amide (L-HABA) moiety attached to N-1 (compare to kanamycin, which simply ... It is derived from kanamycin. Amikacin is most often used for treating severe infections with multidrug-resistant, aerobic Gram ...

... (INN; kanamycin B) is an aminoglycoside antibiotic. Morales MA, Castrillon JL, Hernandez DA (1993). "Effects of ...

Susceptible to ethambutol, rifampin and kanamycin. Resistant to isoniazid, pyrazinamide and streptomycin. Differential ...

Susceptible to ethambutol, ethionamide, kanamycin and cycloserine. Differential characteristics Antigenic structure: ...

Kanamycin resistance is used as a selectable marker. A. brasilense has a high evolutionary adaptation rate driven by codon ...

Total synthesis of a gene encoding kanamycin resistance". Beilstein Journal of Organic Chemistry. 10: 2348-2360. doi:10.3762/ ...

This gene gave bacterial cells and chloroplasts resistance to multiple antibiotics, including kanamycin. The kanamycin- ... Kanamycin is toxic to chloroplasts and is deadly for some plants. When researchers exposed tomato plants to high levels of ... The Flavr Savr also contained a kanamycin-resistance gene. ... kanamycin, only plants with the added genes survived. The FDA ... which confers resistance to certain aminoglycoside antibiotics including kanamycin and neomycin. On May 18, 1994, the FDA ...

M. saopaulense is susceptible to amikacin, kanamycin, and clarithromycin. Nogueira CL, Whipps CM, Matsumoto CK, Chimara E, Droz ...

Abou-Zeid, A. A.; Salem, H. M.; Essa, A. I. (24 January 2007). "Factors influencing the production of kanamycin by Streptomyces ...

The systematic name of this enzyme class is acetyl-CoA:kanamycin-B N6'-acetyltransferase. Other names in common use include ... Le Goffic F, Martel A (1974). "[Resistance to aminosides induced by an isoenzyme, kanamycin acetyltransferase]". Biochimie. 56 ... and kanamycin acetyltransferase. As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession ... the two substrates of this enzyme are acetyl-CoA and kanamycin B, whereas its two products are CoA and N6'-acetylkanamycin-B. ...

A plasmid named pCG113 containing kanamycin resistance genes and the IS1096 insertion sequence was engineered to contain ... Colonies were plated on kanamycin to select for resistant cells. Colonies that underwent random transposition events were ...

"Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation". Nature Chemical Biology. 7 (11): 843- ...

Sakon J, Liao HH, Kanikula AM, Benning MM, Rayment I, Holden HM (November 1993). "Molecular structure of kanamycin ... such as kanamycin, gentamicin, streptomycin, were once effective against staphylococcal infections until strains evolved ...

... resistance is conferred by either one of two kanamycin kinase genes. Genes conferring neomycin-resistance are commonly ... October 2011). "Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation". Nature Chemical ...

"Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation". Nature Chemical Biology. 7 (11): 843- ...

"Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation". Nature Chemical Biology. 7 (11): 843- ...

Bohm's medium uses sodium azide, kanamycin, phenol, and water blue. Shimoji's selective enrichment broth contains tryptic soy ... A commonly used medium is Erysipelothrix selective broth (ESB), a nutrient broth containing serum, tryptose, kanamycin, ...

... hydroxyparomamine This enzyme is involved in the biosynthesis of kanamycin B and kanamycin C. Park JW, Park SR, Nepal KK, Han ... AR, Ban YH, Yoo YJ, Kim EJ, Kim EM, Kim D, Sohng JK, Yoon YJ (October 2011). "Discovery of parallel pathways of kanamycin ...

Carrer, H, Hockenberry, TN, Svab, Z, Maliga, P (October 2004). "Kanamycin resistance as a selectable marker for plastid ...

Humans consuming apples do not acquire kanamycin resistance, per arcticapple.com. The FDA approved the apples in March 2015. ... The trait includes a bacterial antibiotic resistance gene that provides resistance to the antibiotic kanamycin. The genetic ... engineering involved cultivation in the presence of kanamycin, which allowed only resistant cultivars to survive. ...

For example, kanamycin capped gold-nanoparticles (Kan-AuPs) showed broad spectrum dose dependent antibacterial activity against ... "Novel Synthesis of Kanamycin Conjugated Gold Nanoparticles with Potent Antibacterial Activity". Frontiers in Microbiology. 7. ... both gram positive and gram negative bacterial strains in comparison to kanamycin alone. Colloidal silver Gold nanorods Gold ...

It is the species from which the antibiotic kanamycin is isolated. Garrod, L.P., et al.: "Antibiotic and Chemotherapy", page ...

Carrer, Helaine; Hockenberry, Tish Noel; Svab, Zora; Maliga, Pal (October 1993). "Kanamycin resistance as a selectable marker ... it will typically be a gene granting cells a detoxification capacity for certain herbicides or antibiotics such as kanamycin, ...

The resistance genes confer resistance to the antibiotics kanamycin, ampicillin and tetracycline. In addition, RK2 contains a ...

PCC6803 the ideal concentrations of kanamycin, spectinomycin, streptomycin, chloramphenicol, erythromycin, and gentamicin. ...

Kondo S, Iinuma K, Yamamoto H, Maeda K, Umezawa H (1973). "Letter: Syntheses of 1-n-(S)-4-amino-2-hydroxybutyryl)-kanamycin B ... Arbekacin (INN) is a semisynthetic aminoglycoside antibiotic which was derived from kanamycin. It is primarily used for the ... and -3', 4'-dideoxykanamycin B active against kanamycin-resistant bacteria". Journal of Antibiotics. 26 (7): 412-415. doi: ...