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*  Aminoacyl tRNA synthetases, class I
The synthetases specific for arginine, cysteine, glutamic acid, glutamine, isoleucine, leucine, methionine, tyrosine, ...
*  Protein metabolism
Asparagine Glutamine Special cases Cysteine Selenocysteine Glycine Proline Hydrophobic side chains Alanine Valine Isoleucine ...
*  Essential amino acid
The role of isoleucine; additional evidence concerning histidine" (PDF). J Biol Chem. 193 (2): 605-612. PMID 14907749. ... isoleucine, lysine, and histidine (i.e., F V T W M L I K H). Six other amino acids are considered conditionally essential in ... isoleucine, methionine, valine, and arginine, in addition to threonine. Rose's later work showed that eight amino acids are ...
*  Isoleucine-tRNA ligase
... isoleucine-transfer RNA ligase, isoleucine-tRNA synthetase, and isoleucine translase. This enzyme participates in valine, ... In enzymology, an isoleucine-tRNA ligase (EC 6.1.1.5) is an enzyme that catalyzes the chemical reaction ATP + L-isoleucine + ... The systematic name of this enzyme class is L-isoleucine:tRNAIle ligase (AMP-forming). Other names in common use include ... L-isoleucine, and tRNA(Ile), whereas its 3 products are AMP, diphosphate, and L-isoleucyl-tRNA(Ile). This enzyme belongs to the ...
*  Isoleucine N-monooxygenase
... (EC 1.14.13.117, CYP79D3, CYP79D4) is an enzyme with systematic name L-isoleucine,NADPH:oxygen ... N-hydroxy-L-isoleucine + NADP+ + H2O (1b) N-hydroxy-L-isoleucine + O2 + NADPH + H+ ⇌ {\displaystyle \rightleftharpoons } N,N- ... dihydroxy-L-isoleucine + NADP+ + H2O (1c) N,N-dihydroxy-L-isoleucine ⇌ {\displaystyle \rightleftharpoons } (E)-2-methylbutanal ... Isoleucine N-monooxygenase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular ...
*  Amino acid
... isoleucine, and valine. Proline is the only proteinogenic amino acid whose side-group links to the α-amino group and, thus, is ...
*  Ribonuclease inhibitor
valine, isoleucine, methionine, tyrosine, and phenylalanine. RI is the classic leucine-rich repeat protein, consisting of ...
*  Chaetomium cupreum
... leucine and isoleucine degradation; valine, leucine, isoleucine, tyrosine and tryptophan biosynthesis. Proteases produced by C ...
*  Acetolactate decarboxylase
Hill RK, Sawada S, Arfin SM (1979). "Stereochemistry of valine and isoleucine biosynthesis. IV Synthesis, configuration, and ...
*  Amino acid synthesis
This operon is bound and inactivated by valine, leucine, and isoleucine. (Isoleucine is not a direct derivative of pyruvate, ... High concentrations of isoleucine also result in the downregulation of aspartate's conversion into the aspartyl-phosphate ... I.e. the presence of isoleucine will downregulate the formation of all three enzymes, resulting in the downregulation of ... Threonine also gives rise to isoleucine. All of these amino acids contain different mechanisms for their regulation, some being ...
*  Thiolase
Daum RS, Lamm PH, Mamer OA, Scriver CR (December 1971). "A "new" disorder of isoleucine catabolism". Lancet. 2 (7737): 1289-90 ... is an inborn error of metabolism involving isoleucine catabolism and ketone body metabolism. The major clinical manifestations ...
*  Ketol-acid reductoisomerase
This enzyme participates in valine, leucine and isoleucine biosynthesis and pantothenate and coa biosynthesis. As of late 2007 ... Hill RK, Sawada S & Arfin SM (1979). "Stereochemistry of valine and isoleucine biosynthesis. IV Synthesis, configuration, and ... Satyanarayana T, Radhakrishnan AN (1965). "Biosynthesis of valine and isoleucine in plants. 3. Reductoisomerase of Phaseolus ...
*  Coiled coil
Harbury PB, Kim PS, Alber T (Sep 1994). "Crystal structure of an isoleucine-zipper trimer". Nature. 371 (6492): 80-3. doi: ... coiled coil and has a repeated isoleucine (or I, in single-letter code) and leucine (L) at the a and d positions, respectively ... often being occupied by isoleucine, leucine, or valine. Folding a sequence with this repeating pattern into an alpha-helical ...
*  Roswell Park Memorial Institute medium
... and isoleucine; 40mg lysine hydrochloride; 30mg serine; 20mg each aspartic acid, glutamic acid, hydroxyproline, proline, ...
*  Tyrosine aminotransferase
Lys280 is attached to PLP, which is held in place via two nonpolar amino acid side chains; phenylalanine and isoleucine (see ...
*  Threonine ammonia-lyase
The enzyme has two binding sites for isoleucine; one has a high affinity for isoleucine and the other has a low affinity. The ... humans cannot convert threonine into isoleucine and must consume isoleucine in the diet. The enzyme has also been studied in ... The enzyme is inhibited by isoleucine, the product of the pathway it participates in, and is activated by valine, the product ... Alpha-ketobutyrate can be converted into L-isoleucine, so threonine ammonia-lyase functions as a key enzyme in BCAA synthesis. ...
*  2-methyl-branched-chain-enoyl-CoA reductase
This enzyme participates in the degradation of isoleucine. It employs one cofactor, FAD. Komuniecki R, Fekete S, Thissen-Parra ...
*  Streptomyces flaveolus
... produces L-isoleucine, actinomycin J and tirandamycin. Qu, Xudong; Lei, Chun; Liu, Wen (4 October 2011 ...
*  Valine-pyruvate transaminase
This enzyme participates in valine, leucine and isoleucine biosynthesis. Falkinham JO 3rd (1979). "Identification of a mutation ...
*  3-hydroxy-2-methylbutyryl-CoA dehydrogenase
Conrad RS, Massey LK, Sokatch JR (1974). "D- and L-isoleucine metabolism and regulation of their pathways in Pseudomonas putida ... This enzyme participates in valine, leucine and isoleucine degradation. As of 20 January 2010, 6 structure have been solved for ...
*  3-hydroxyisobutyrate dehydrogenase
This enzyme participates in valine, leucine and isoleucine degradation. 3-hydroxyisobutyrate dehydrogenase is a tetrameric ...
*  2-oxoisovalerate dehydrogenase (acylating)
This enzyme participates in valine, leucine and isoleucine degradation. Namba Y, Yoshizawa K, Ejima A, Hayashi T, Kaneda T ( ...
*  2-acetolactate mutase
This enzyme participates in valine, leucine and isoleucine biosynthesis. It employs one cofactor, ascorbate. Allaudeen HS, ... Ramakrishnan T (1968). "Biosynthesis of isoleucine and valine in Mycobacterium tuberculosis H37 Rv". Arch. Biochem. Biophys. ...
*  Leucines
Including the stereoisomers, six further isomers could be added: D-leucine, D-isoleucine, L-allo-isoleucine, D-allo-isoleucine ... Leucine and isoleucine belong to the proteinogenic amino acids; the others are non-natural. ... The leucines are primarily the four isomeric amino acids: leucine, isoleucine, tert-leucine and norleucine. Being compared with ...
*  Leucine 2,3-aminomutase
This enzyme participates in valine, leucine and isoleucine degradation. It employs one cofactor, cobamide. Freer I, Pedrocchi- ...