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*  Neurexin
Boschero AC, Negreiros de Paiva CE (1977). "Transplantation of islets of Langerhans in diabetic rats". Acta Physiol Lat Am. 27 ...
*  TMSB10
2003). "Inflammatory mediators expressed in human islets of Langerhans: implications for islet transplantation". Biochem. ...
*  Islet cell transplantation
Scharp D, Murphy J, Newton W, Ballinger W, Lacy P (1975). "Transplantation of islets of Langerhans in diabetic rhesus monkeys ... Islet transplantation is the transplantation of isolated islets from a donor pancreas into another person. It is an ... The goal of islet transplantation is to infuse enough islets to control the blood glucose level removing the need for insulin ... Like all transplantation therapies, islet transplantation is also handicapped by the limited donor pool. The numbers are ...
*  List of MeSH codes (E04)
... islets of langerhans transplantation MeSH E04.936.225.687 --- stem cell transplantation MeSH E04.936.225.687.155 --- bone ... islets of langerhans transplantation MeSH E04.270.694 --- parathyroidectomy MeSH E04.270.856 --- thyroidectomy MeSH E04.292.413 ... heart-lung transplantation MeSH E04.936.450.485 --- kidney transplantation MeSH E04.936.450.490 --- liver transplantation MeSH ... fetal tissue transplantation MeSH E04.936.580.490 --- liver transplantation MeSH E04.936.580.700 --- skin transplantation MeSH ...
*  Organ transplantation
Islets of Langerhans (pancreas islet cells) (deceased-donor and living-donor) Bone marrow/Adult stem cell (living-donor and ... Thyroid transplantation became the model for a whole new therapeutic strategy: organ transplantation. After the example of the ... "ABO Incompatible Heart Transplantation in Young Infants". American Society of Transplantation. 30 July 2009. Archived from the ... Kidney Transplantation, Bioengineering, and Regeneration: Kidney Transplantation in the Regenerative Medicine Era, edited by ...
*  Ficoll
... with enough islet recovery from the original tissue, for safe and effective islet transplantation in humans. Because Ficoll- ... Ficoll was used in an attempt to separate islets of Langerhans from enzyme (collagenase) digested human pancreatic tissue. The ... theory was that separated islets could then be used for transplantation into patients with type 1 diabetes. In practice, using ... At one time, fairly early in the research for diabetes treatment by transplantation, ...
*  Glossary of diabetes
Islet cell Transplantation Moving the beta (islet) cells from a donor pancreas and putting them into a person whose pancreas ... Islets of Langerhans Groups of cells in the pancreas. Some of them make and secrete hormones that help the body break down and ... Beta cell transplantation See: Islet cell transplantation. Biosynthetic human insulin A man-made insulin that is chemically ... Insulin a hormone produced by the beta cells in the Islet of Langerhans' beta cells. It is a very small protein and has effects ...
*  Artificial cell
... s have been successful for transplanting a number of cells including islets of Langerhans for diabetes treatment ... "Insulin independence in a type 1 diabetic patient after encapsulated islet transplantation". The Lancet. 343 (8903): 950-951. ... "What clinical alternatives to whole liver transplantation? Current status of artificial devices and hepatocyte transplantation ... This principle has been used to remove blood group antibodies from plasma for bone marrow transplantation and for the treatment ...
*  Stefan R. Bornstein
2013). Transplantation of human islets without immunosuppression. In: Proceedings of the National Academy of Sciences. doi: ... and one of the coordinators of the Paul-Langerhans-Institute Dresden. Since 2012, he has been scientific secretary of the DFG ... In 2008 started the only currently active program of islet transplantation in Germany. This treatment is a great benefit for ... stem cell research and advances in islet cell transplantation as a therapy for diabetes. This is why, presently, Dresden is the ...
*  Paul Eston Lacy
He is often credited as the originator of islet transplantation. Lacy was born in Trinway, Ohio in February, 1924. He was ... That work resulted in a better understanding of how beta cells in the pancreatic islets of Langerhans produced and exported ... Ballinger WF II, Lacy PE: Transplantation of intact pancreatic islets in rats. Surgery 1972; 72: 175-186. Ballinger WF II, Lacy ... Scharp DW, Lacy PE, Santiago JV, et al.: Insulin independence after islet transplantation into type I diabetic patient. ...
*  Insulin oscillation
Insulin originates from beta cells located in the islets of Langerhans. Since each islet contains up to 2000 beta cells and ... Pulsatile insulin delivery to the portal vein or islet cell transplantation to the liver of diabetic patients are therefore ... within an islet of Langerhans the oscillations become synchronized by electrical coupling between closely located beta cells ... This signal is believed to entrain pulsatile insulin release from the islets into a common pancreatic rhythm. The insulin ...
*  Directed differentiation
Langerhans islet beta-cells, cardiomyocytes and neurons. Drug screen are performed on miniaturized cell culture in multiwell- ... Source material can be normal healthy cells from another donor (heterologous transplantation) or genetically corrected from the ... cell replacement and transplantation following acute injuries and reconstructive surgery. These applications are limited to the ... "Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets". Science. National Center ...
*  Insulin
... while leaving the islets of Langerhans intact. He theorized a relatively pure extract could be made from the islets once most ... This may be achieved by delivering insulin rhythmically to the portal vein or by islet cell transplantation to the liver. The ... Beta cells in the islets of Langerhans release insulin in two phases. The first-phase release is rapidly triggered in response ... The function of the "little heaps of cells", later known as the islets of Langerhans, initially remained unknown, but Edouard ...
*  Santa J. Ono
II MHC gene products are expressed at higher levels or de novo on the insulin-producing beta cells of the islets of Langerhans ... At Harvard, he served as head of the Inflammation, Immunity and Transplantation Focus Group at the Schepens Eye Research ... Enhanced MHC class I heavy-chain gene expression in pancreatic islets". Diabetes. 37 (10): 1411-8. doi:10.2337/diabetes.37.10. ...
*  Immune tolerance
the T cell did not encounter in the thymus (such as, tissue-specific molecules like those in the islets of Langerhans, brain, ... Braza, F; Soulillou JP; Brouard S. (Sep 2012). "Gene expression signature in transplantation tolerance". Clin Chim Acta. 413 ( ... Immune recognition of non-self-antigens typically complicates transplantation and engrafting of foreign tissue from an organism ... which could be rescued by transplantation of CD4+ T cells. A more specific depletion and reconstitution experiment established ...
*  Testicular immunology
Selawry HP, Cameron DF (1993). "Sertoli cell-enriched fractions in successful islet cell transplantation". Cell Transplant. 2 ( ... islets of Langerhans), resulting in increased graft survival. Molecules released by the Sertoli cells are predicted to protect ... ISBN 978-0-12-515401-7. Setchel BP (1990). "The testis and tissue transplantation: historical aspects". J Reprod Immunol. 18 (1 ... Korbutt GS, Elliott JF, Rajotte RV (1997). "Cotransplantation of allogeneic islets with allogeneic testicular cell aggregates ...
*  Diabetes mellitus type 1
Islet cell transplantation may be an option for some people with type 1 diabetes that are not well controlled with insulin. ... pancreatic beta cells in the islets of Langerhans are destroyed, decreasing endogenous insulin production. This distinguishes ... Bruni, A; Gala-Lopez, B; Pepper, AR; Abualhassan, NS; Shapiro, AJ (2014). "Islet cell transplantation for the treatment of type ... It is used in research for inducing type 1 diabetes on rodents and for treating metastatic cancer of the pancreatic islet cells ...
*  Cystic fibrosis
The pancreas contains the islets of Langerhans, which are responsible for making insulin, a hormone that helps regulate blood ... Lung transplantation may be an option if lung function continues to worsen. Pancreatic enzyme replacement and fat-soluble ... Damage of the pancreas can lead to loss of the islet cells, leading to a type of diabetes unique to those with the disease. ... Although single lung transplantation is possible in other diseases, individuals with CF must have both lungs replaced because ...
*  Index of oncology articles
... islet cell - islet cell cancer - islet of Langerhans cell - isoflavone - isointense - isolated hepatic perfusion - isolated ... syngeneic bone marrow transplantation - syngeneic stem cell transplantation - synovial membrane - synovial sarcoma - synthetic ... allogeneic bone marrow transplantation - allogeneic stem cell transplantation - allogenic - allopurinol - Allovectin-7 - aloe- ... autologous bone marrow transplantation - autologous lymphocyte - autologous stem cell transplantation - autologous tumor cell ...
*  Diabetes mellitus
Insulin is released into the blood by beta cells (β-cells), found in the islets of Langerhans in the pancreas, in response to ... "Pancreas Transplantation". American Diabetes Association. Archived from the original on 13 April 2014. Retrieved 9 April 2014. ... Type 1 diabetes mellitus is characterized by loss of the insulin-producing beta cells of the pancreatic islets, leading to ... sometimes requiring dialysis or kidney transplantation. Damage to the nerves of the body, known as diabetic neuropathy, is the ...
*  Pancreas
Islets of Langerhans have a well-established structure and form density routes through the exocrine tissue. The exocrine part ... An experimental procedure to treat type 1 diabetes is the transplantation of pancreatic islet cells from a donor into the ... The islets are crisscrossed by a dense network of capillaries. The capillaries of the islets are lined by layers of islet cells ... Lakey, JR; Burridge, PW; Shapiro, AM (September 2003). "Technical aspects of islet preparation and transplantation". Transplant ...
*  Cell encapsulation
July 2000). "Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free ... have been dedicated towards the development of bioartificial pancreas involving the immobilization of islets of Langerhans ... "Considerations for successful transplantation of encapsulated pancreatic islets". Diabetologia. 45 (2): 159-73. doi:10.1007/ ... The use of microencapsulation would protect the islet cells from immune rejection as well as allow the use of animal cells or ...