Boschero AC, Negreiros de Paiva CE (1977). "Transplantation of islets of Langerhans in diabetic rats". Acta Physiol Lat Am. 27 ...

Scharp DW, Murphy JJ, Newton WT, Ballinger WF, Lacy PE (January 1975). "Transplantation of islets of Langerhans in diabetic ... Islet transplantation is the transplantation of isolated islets from a donor pancreas into another person. It is a treatment ... The goal of islet transplantation is to infuse enough islets to control the blood glucose level removing the need for insulin ... and the limited supply of islets for transplantation. Current immunosuppressive regimens are capable of preventing islet ...

2003). "Inflammatory mediators expressed in human islets of Langerhans: implications for islet transplantation". Biochem. ...

Islet cell Transplantation Moving the beta (islet) cells from a donor pancreas and putting them into a person whose pancreas ... Islets of Langerhans Groups of cells in the pancreas. Some of them make and secrete hormones that help the body break down and ... Beta cell transplantation See: Islet cell transplantation. Biosynthetic human insulin A man-made insulin that is chemically ... Insulin a hormone produced by the beta cells in the Islet of Langerhans' beta cells. It is a very small protein and has effects ...

Insulin originates from beta cells located in the islets of Langerhans. Since each islet contains up to 2000 beta cells and ... Pulsatile insulin delivery to the portal vein or islet cell transplantation to the liver of diabetic patients are therefore ... The islets of Langerhans. Md. Shahidul Islam. Dordrecht: Springer. 2010. ISBN 978-90-481-3271-3. OCLC 663096203. Insulin ... within an islet of Langerhans the oscillations become synchronized by electrical coupling between closely located beta cells ...

... with enough islet recovery from the original tissue, for safe and effective islet transplantation in humans. Because Ficoll- ... Ficoll was used in an attempt to separate islets of Langerhans from enzyme (collagenase) digested human pancreatic tissue. The ... theory was that separated islets could then be used for transplantation into patients with type 1 diabetes. In practice, using ... At one time, fairly early in the research for diabetes treatment by transplantation, ...

Islets of Langerhans (pancreas islet cells) (deceased-donor and living-donor) Bone marrow or adult stem cell (living-donor and ... Thyroid transplantation became the model for a whole new therapeutic strategy: organ transplantation. After the example of the ... Kidney Transplantation, Bioengineering, and Regeneration: Kidney Transplantation in the Regenerative Medicine Era, edited by ... "Transplantation: Catalan pioneers". Retrieved 10 December 2022. Roy Calne. Essay History of transplantation. Lancet 2006; 368: ...

"Three-yr follow-up of a type 1 diabetes mellitus patient with an islet xenotransplant". Clinical Transplantation. 21 (3): 352- ... "Xenotransplantation of porcine neonatal islets of Langerhans and Sertoli cells: a 4-year study". European Journal of ...

... s have been successful for transplanting a number of cells including islets of Langerhans for diabetes treatment ... April 1994). "Insulin independence in a type 1 diabetic patient after encapsulated islet transplantation". Lancet. 343 (8903): ... Current status of artificial devices and hepatocyte transplantation". Transplantation. 87 (4): 457-466. doi:10.1097/TP. ... This principle has been used to remove blood group antibodies from plasma for bone marrow transplantation and for the treatment ...

... islets of langerhans transplantation MeSH E04.936.225.687 - stem cell transplantation MeSH E04.936.225.687.155 - bone marrow ... islets of langerhans transplantation MeSH E04.270.694 - parathyroidectomy MeSH E04.270.856 - thyroidectomy MeSH E04.292.413 - ... heart transplantation MeSH E04.936.450.475.450 - heart-lung transplantation MeSH E04.936.450.485 - kidney transplantation MeSH ... lung transplantation MeSH E04.936.450.495.450 - heart-lung transplantation MeSH E04.936.450.650 - pancreas transplantation MeSH ...

In 2008 started the only currently active program of islet transplantation in Germany. This treatment is a great benefit for ... and one of the coordinators of the Paul-Langerhans-Institute Dresden. Since 2012, he has been scientific secretary of the DFG ... stem cell research and advances in islet cell transplantation as a therapy for diabetes. This is why, presently, Dresden is the ... DFG TRansregio 127 Transplantation of human islets without immunosuppression CV Bornstein (Articles with ISNI identifiers, ...

"Xenotransplantation of porcine neonatal islets of Langerhans and Sertoli cells: a 4-year study". European Journal of ... Upon xenogenic transplantation, Sertoli cells have been shown to regain the ability to proliferate. Recently (2016), ... By treating spontaneously diabetic and obese mice with the transplantation of microencapsulated Sertoli cells in subcutaneous ... Korbutt GS, Elliott JF, Rajotte RV (February 1997). "Cotransplantation of allogeneic islets with allogeneic testicular cell ...

... islet cells are obtained from the patient, whereas in the allogeneic pancreatic islet cell transplantation islet cells were ... Schmidt observed inflammation caused by lymphocytic infiltration in the islets of Langerhans in the periphery of islets (peri- ... Due to the islets of Langerhans being small clusters of cells in the pancreas, it is difficult to study and diagnose insulitis ... Insulitis is an inflammation of the islets of Langerhans, a collection of endocrine tissue located in the pancreas that helps ...

Insulin independence after islet transplantation into type I diabetic patient. Diabetes 1990; 39: 515-518. "Pancreatic Islet ... That work resulted in a better understanding of how beta cells in the pancreatic islets of Langerhans produced and exported ... He is often credited as the originator of islet transplantation. Lacy was born in Trinway, Ohio in February, 1924. He was ... Ballinger WF II, Lacy PE: Transplantation of intact pancreatic islets in rats. Surgery 1972; 72: 175-186. Ballinger WF II, Lacy ...

Langerhans islet beta-cells, cardiomyocytes and neurons. Drug screen are performed on miniaturized cell culture in multiwell- ... Source material can be normal healthy cells from another donor (heterologous transplantation) or genetically corrected from the ... cell replacement and transplantation following acute injuries and reconstructive surgery. These applications are limited to the ... "Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets". Science. 292 (5520): ...

... while leaving the islets of Langerhans intact. He reasoned that a relatively pure extract could be made from the islets once ... or by islet cell transplantation to the liver. The blood insulin level can be measured in international units, such as µIU/mL ... Beta cells in the islets of Langerhans release insulin in two phases. The first-phase release is rapidly triggered in response ... The function of the "little heaps of cells", later known as the islets of Langerhans, initially remained unknown, but Édouard ...

II MHC gene products are expressed at higher levels or de novo on the insulin-producing beta cells of the islets of Langerhans ... At Harvard, he served as head of the Inflammation, Immunity and Transplantation Focus Group at the Schepens Eye Research ... Enhanced MHC class I heavy-chain gene expression in pancreatic islets". Diabetes. 37 (10): 1411-8. doi:10.2337/diabetes.37.10. ...

the T cell did not encounter in the thymus (such as, tissue-specific molecules like those in the islets of Langerhans, brain, ... Braza, F; Soulillou JP; Brouard S. (Sep 2012). "Gene expression signature in transplantation tolerance". Clin Chim Acta. 413 ( ... Immune recognition of non-self-antigens typically complicates transplantation and engrafting of foreign tissue from an organism ... which could be rescued by transplantation of CD4+ T cells. A more specific depletion and reconstitution experiment established ...

Selawry HP, Cameron DF (1993). "Sertoli cell-enriched fractions in successful islet cell transplantation". Cell Transplantation ... islets of Langerhans), resulting in increased graft survival. Molecules released by the Sertoli cells are predicted to protect ... ISBN 978-0-12-515401-7. Setchel BP (1990). "The testis and tissue transplantation: historical aspects". Journal of Reproductive ... Korbutt GS, Elliott JF, Rajotte RV (1997). "Cotransplantation of allogeneic islets with allogeneic testicular cell aggregates ...

The pancreas contains the islets of Langerhans, which are responsible for making insulin, a hormone that helps regulate blood ... October 2005). "Simultaneous liver and pancreas transplantation in patients with cystic fibrosis". Transplantation Proceedings ... Damage to the pancreas can lead to loss of the islet cells, leading to a type of diabetes unique to those with the disease. ... Lung transplantation may be an option if lung function continues to worsen. Pancreatic enzyme replacement and fat-soluble ...

... islet cell - islet cell cancer - islet of Langerhans cell - isoflavone - isointense - isolated hepatic perfusion - isolated ... syngeneic bone marrow transplantation - syngeneic stem cell transplantation - synovial membrane - synovial sarcoma - synthetic ... allogeneic bone marrow transplantation - allogeneic stem cell transplantation - allogenic - allopurinol - Allovectin-7 - aloe- ... autologous bone marrow transplantation - autologous lymphocyte - autologous stem cell transplantation - autologous tumor cell ...

Paul Langerhans: Islets of Langerhans, Langerhans cells Max von Laue: Discoveries regarding the diffraction of X-rays in ... Pioneer of skin transplantation and cosmetic surgery. Ernst Dickmanns: Developer of the first driverless car. Otto Diels: Diels ...

Insulin is released into the blood by beta cells (β-cells), found in the islets of Langerhans in the pancreas, in response to ... "Pancreas Transplantation". American Diabetes Association. Archived from the original on 13 April 2014. Retrieved 9 April 2014. ... However, islet autoimmunity and multiple antibodies can be a strong predictor of the onset of type 1 diabetes. Type 2 diabetes- ... The disease is characterized by loss of the insulin-producing beta cells of the pancreatic islets, leading to severe insulin ...

An experimental procedure to treat type 1 diabetes is pancreas transplantation or isolated transplantation of islet cells to ... also called islets of Langerhans) that are distributed throughout the pancreas. Pancreatic islets contain alpha cells, beta ... more numerous and found throughout the islet. Enterochromaffin cells are also scattered throughout the islets. Islets are ... The pancreatic islets form as the endocrine cells migrate from the duct system to form small clusters around capillaries. This ...

... polypeptide receptor List of terms associated with diabetes Guangxitoxin Alpha cell Pancreatic development Islets of Langerhans ... "Differentiation and transplantation of functional pancreatic beta cells generated from induced pluripotent stem cells derived ... Beta cells make up 50-70% of the cells in human islets. In patients with Type 1 diabetes, beta-cell mass and function are ... Cilia deletion can lead to islet dysfunction and type 2 diabetes. Beta cells are the only site of insulin synthesis in mammals ...

July 2000). "Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free ... have been dedicated towards the development of bioartificial pancreas involving the immobilization of islets of Langerhans ... "Considerations for successful transplantation of encapsulated pancreatic islets". Diabetologia. 45 (2): 159-73. doi:10.1007/ ... The use of microencapsulation would protect the islet cells from immune rejection as well as allow the use of animal cells or ...