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*  Iron overload
Human iron metabolism Iron deficiency Hider, Robert C.; Kong, Xiaole (2013). "Chapter 8. Iron: Effect of Overload and ... Iron overload, also known as haemochromatosis, indicates accumulation of iron in the body from any cause. The most important ... doi:10.1007/978-94-007-7500-8_8. Lu JP, Hayashi K. Selective iron deposition in pancreatic islet B cells of transfusional iron- ... Lu JP, Hayashi K. Transferrin receptor distribution and iron deposition in the hepatic lobule of iron-overloaded rats. Pathol ...
*  Aceruloplasminemia
Iron accumulation in the tissues and organs results in a corresponding iron deficiency in the blood, leading to anemia. Anemia ... Human iron metabolism Iron overload disorder Harris, Zl; Takahashi, Y; Miyajima, H; Serizawa, M; Macgillivray, Rt; Gitlin, Jd ( ... When ceruloplasmin is unavailable, transport of iron out of the body's tissues is impaired. The resulting iron accumulation ... Those at risk should avoid taking iron supplements. Treatment includes the use of iron chelating agents (such as ...
*  Hepcidin
It reduces extracellular iron in the body by several mechanisms: 1) It lowers dietary iron absorption by reducing iron ... Hepcidin is a regulator of iron metabolism. Hepcidin inhibits iron transport by binding to the iron export channel ferroportin ... There are many diseases where failure to adequately absorb iron contributes to iron deficiency and iron deficiency anaemia. The ... serum iron falls due to iron trapping within macrophages and liver cells and decreased gut iron absorption. This typically ...
*  Transferrin
Although iron bound to transferrin is less than 0.1% (4 mg) of total body iron, it forms the most vital iron pool with the ... A high transferrin level may indicate an iron deficiency anemia. Levels of serum iron and total iron binding capacity (TIBC) ... For the iron ion to bind, an anion is required, preferably carbonate (CO2− 3). Transferrin also has a transferrin iron-bound ... Transferrins are iron-binding blood plasma glycoproteins that control the level of free iron (Fe) in biological fluids. Human ...
*  Wrought iron
Lukes iron-iron imported from Liège, whose Dutch name is "Luik." Ames iron or amys iron-another variety of iron imported to ... Pig iron and cast iron have higher carbon content than wrought iron, but have a lower melting point than iron or steel. Cast ... Blend iron Made using a mixture of different types of pig iron. Best iron Iron put through several stages of piling and rolling ... The molten pig iron is manually stirred, exposing the iron to atmospheric oxygen, which decarburizes the iron. As the iron is ...
*  Transferrin saturation
It is the value of serum iron divided by the total iron-binding capacity. Of the transferrin that is available to bind iron, ... For instance, a value of 15% means that 15% of iron-binding sites of transferrin are being occupied by iron. For an explanation ... Normal reference ranges are: Serum iron: 60-170 μg/dL (10-30 μmol/L) Total iron-binding capacity: 240-450 μg/dL Transferrin ... this value tells a clinician how much serum iron is bound. ... see Total iron-binding capacity. The three results are usually ...
*  Transferrin receptor
Although TfR1 mediated iron uptake is the major pathway for iron acquisition by most cells and especially developing ... It is needed for the import of iron into the cell and is regulated in response to intracellular iron concentration. It imports ... Low iron concentrations promote increased levels of transferrin receptor, to increase iron intake into the cell. Thus, ... TfR production in the cell is regulated according to iron levels by iron-responsive element-binding proteins, IRP1 and IRP2. In ...
*  Iron deficiency
Mild iron deficiency can be prevented or corrected by eating iron-rich foods and by cooking in an iron skillet. Because iron is ... iron in meat (heme-iron source) is more easily absorbed than iron in grains and vegetables ("non-heme" iron sources). Minerals ... When loss of iron is not sufficiently compensated by adequate intake of iron from the diet, a state of iron deficiency develops ... Iron deficiency happens when a body has not enough (or not qualitatively enough) iron to supply its eventual needs. Iron is ...
*  Total iron-binding capacity
"Total iron-binding capacity calculated from serum transferrin concentration or serum iron concentration and unsaturated iron- ... Total iron-binding capacity (TIBC) or sometimes transferrin iron-binding capacity is a medical laboratory test that measures ... Kasvosve I, Delanghe J (October 2002). "Total iron binding capacity and transferrin concentration in the assessment of iron ... iron deficiency or iron deficiency anemia. However, because the liver produces transferrin, alterations in function (such as ...
*  Siderophore
Virtually all this iron is in the iron(III) state and complexed to organic ligands. These low levels of iron limit the primary ... The iron(III) complex is then reduced to iron(II) and the iron is transferred to nicotianamine, which although very similar to ... the production of iron-siderophore binding proteins and the general "withdrawal"of iron. There are two major types of iron- ... generated via photochemical decomposition of iron(III) siderophores. Thus a large proportion of iron (possibly all iron) ...
*  HAMP
... and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is ... Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron ... "Entrez Gene: HAMP hepcidin antimicrobial peptide". Ganz T (2003). "Hepcidin, a key regulator of iron metabolism and mediator of ... 2003). "Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic ...
*  Iron response element
Page for Iron response element - Model I at Rfam Page for Iron response element - Model II at Rfam Transterm page for Iron ... the iron response element or iron-responsive element (IRE) is a short conserved stem-loop which is bound by iron response ... "Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network". Annual Review ... When Iron is present, it interacts with the protein to cause it to release the mRNA. For example, In high iron conditions in ...
*  Hemojuvelin
... the central iron regulatory hormone. As a result, low hepcidin levels would result in increased intestinal iron absorption. ... Niederkofler V, Salie R, Arber S (August 2005). "Hemojuvelin is essential for dietary iron sensing, and its mutation leads to ... For many years the signal transduction pathways that regulate systemic iron homeostasis have been unknown. However it has been ... Thus, HJV/RGMc appears to play a critical role in iron metabolism.[citation needed] GRCh38: Ensembl release 89: ENSG00000168509 ...
*  Human iron metabolism
However, some of the intracellular iron is bound to low-affinity complexes, and is termed labile iron or "free" iron. Iron in ... The ferritin storage iron pool is much larger than the labile iron pool, ranging in concentration from 0.7 mM to 3.6 mM. Iron ... Absorption of dietary iron in iron salt form (as in most supplements) varies somewhat according to the body's need for iron, ... Since iron is primarily required for hemoglobin, iron deficiency anemia is the primary clinical manifestation of iron ...
*  Ferritin
In humans, it acts as a buffer against iron deficiency and iron overload. Ferritin is found in most tissues as a cytosolic ... It is the primary intracellular iron-storage protein in both prokaryotes and eukaryotes, keeping iron in a soluble and non- ... Serum ferritin levels are measured in medical laboratories as part of the iron studies workup for iron-deficiency anemia. The ... It participates in ferroxidase activity, binding, iron ion binding, oxidoreductase activity, ferric iron binding, metal ion ...
*  Hypochromic anemia
... may be caused by vitamin B6 deficiency from a low iron intake, diminished iron absorption, or excessive iron ... The iron overload aspect of the disorder means that the iron accumulates in the liver and can cause liver impairment in ... It also occurs in patients with hereditary iron refractory iron-deficiency anemia (IRIDA). Patients with IRIDA have very low ... The condition prevents red blood cells from accessing iron in the blood, which causes anemia that is apparent at birth. It can ...
*  Iron cycle
The iron cycle affects dust deposition and aerosol iron bioavailability. Iron ranges in oxidation states from -2 to +7; however ... The cycling of iron between its ferrous and ferric oxidation states is referred to as the iron cycle. This process can be ... In ecology or geoscience, the iron cycle (Fe) is the biogeochemical cycle of iron through landforms, the atmosphere, and oceans ... and the abiotic reduction of Fe3+ to Fe2+ by iron-sulfide minerals. The iron cycle can also be facilitated by microorganisms, ...
*  Carbohydrate deficient transferrin
Transferrin is a serum protein that carries iron through the bloodstream to the bone marrow, where red blood cells are ...
*  Haemochromatosis type 3
... is a type of Iron overload disorder associated with deficiencies in transferrin receptor 2. It exhibits ... Roetto A, Camaschella C (June 2005). "New insights into iron homeostasis through the study of non-HFE hereditary ...
*  Iron
Mild iron deficiency can be prevented or corrected by eating iron-rich foods and by cooking in an iron skillet. Because iron is ... "Direct iron reduction" reduces iron ore to a ferrous lump called "sponge" iron or "direct" iron that is suitable for ... During the Industrial Revolution in Britain, Henry Cort began refining iron from pig iron to wrought iron (or bar iron) using ... iron) and kamacite (90-95% iron). Although rare, iron meteorites are the main form of natural metallic iron on the Earth's ...
*  Iron & Fire
"Iron & Fire". The History Channel. The History Channel. Retrieved April 25, 2016. "Iron & Fire". The History Channel. The ... Iron & Fire is an American reality television series on The History Channel that portrays the lives of Daniel Casey's family & ...
*  Iron Latch
There is access from Iron Latch Lane. "Iron Latch". Essex Wildlife Trust. Retrieved 6 July 2016. Coordinates: 51°53′51″N 0°49′ ... Iron Latch is a 4.3 hectare nature reserve in Eight Ash Green, west of Colchester in Essex. The site consists of areas of ...
*  Iron Pagoda
The pagoda is so-named not because it is made of iron, but because its color resembles that of iron. It is a brick pagoda tower ... In 1994, the Iron Pagoda was featured on a two-yuan Chinese postage stamp. detail detail glazed tiles of Iron Pagoda ... The new tower was built of nonflammable brick and stone and was dubbed the 'Iron Pagoda' due its iron-grey color when viewed ... Iron Pagoda at Ctrip Iron Pagoda at CRIENGLISH. ... The Iron Pagoda (Chinese: 鐵塔) of Youguo Temple (佑國寺), Kaifeng ...
*  Russia iron
... or Russian iron refers to a type of sheet iron produced in Russia during the 19th and early 20th century. This iron ... "Russia Iron". Narrowgauge.iform.com.au. 1998-03-24. Retrieved 2013-10-24. Osborn, Henry Stafford (1869). The Metallurgy of Iron ... This sheet-iron was used in Russia for stove flues and for roofing, among other tasks. Exported in quantity to the United ... Much effort was expended on attempting to duplicate Russia iron in the United States, with varying degrees of success. In The ...
*  Iron Path
... at Discogs (list of releases) Iron Path at Bandcamp. ... Iron Path is the only studio album by the free jazz band Last ... "Iron Path". Allmusic. Retrieved October 18, 2014. Christgau, Robert (November 6, 2015). "You Should Always Listen to More Jazz ...