The human sterol carrier protein 2 (SCP2) is a basic protein that is believed to participate in the intracellular transport of ... Sterol carrier proteins (also known as nonspecific lipid transfer proteins) is a family of proteins that transfer steroids and ... Sterol carrier proteins in SCOP SCP-2 sterol transfer family in Pfam UMich Orientation of Proteins in Membranes families/ ... These proteins are different from plant nonspecific lipid transfer proteins but structurally similar to small proteins of ...

... involved in intracellular organelle transport COG2, COG4, COG5, COG7 Sterol carrier protein Barlan K, Gelfand VI (May 2017). " ... Motor proteins connect the transport vesicles to microtubules and actin filaments to facilitate intracellular movement. ... On the other hand, targeting the intracellular transport processes of these motor proteins constitutes the possibility for ... Rab proteins on the surface of the transport vesicle are responsible for aligning with the complementary tethering proteins ...

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of ... 2001). "Gene structure, intracellular localization, and functional roles of sterol carrier protein-2". Prog. Lipid Res. 40 (6 ... 1994). "Assignment of sterol carrier protein X/sterol carrier protein 2 to 1p32 and its exclusion as the causative gene for ... Ohba T, Holt JA, Billheimer JT, Strauss JF (1995). "Human sterol carrier protein x/sterol carrier protein 2 gene has two ...

Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR ... Strauss JF, Kishida T, Christenson LK, Fujimoto T, Hiroi H (April 2003). "START domain proteins and the intracellular ... StAR-related lipid transfer protein 5 is a protein that in humans is encoded by the STARD5 gene. The protein is a 213 amino ... It is also part of the StarD4 subfamily of START domain proteins, sharing 34% sequence identity with STARD4. The protein is ...

Its expression is induced by decreased sterol concentrations via sterol regulatory binding proteins (SREBP). There is also ... For example, the sterol reductase motifs are common sites of mutation. Overall, there is an estimated carrier frequency (for ... The synthesis of the enzyme HMG-CoA reductase is controlled by sterol regulatory element binding protein (SREBP). This is a ... 7DHC is known to impair intracellular cholesterol transport. It also increases the degradation of HMG-CoA reductase (the enzyme ...

Proteins can associate to form protein complexes, these often contain a set of proteins with similar functions, such as enzymes ... Intracellular membrane traffic: getting proteins sorted". Philos. Trans. R. Soc. Lond. B Biol. Sci. 354 (1388): 1471-8. doi: ... Ohlrogge JB, Kuhn DN, Stumpf PK (March 1979). "Subcellular localization of acyl carrier protein in leaf protoplasts of Spinacia ... Maxfield FR, Mondal M (June 2006). "Sterol and lipid trafficking in mammalian cells". Biochem. Soc. Trans. 34 (Pt 3): 335-9. ...

"Fatty Acid-binding Proteins (FABPs) Are Intracellular Carriers for Δ9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD)". ... However, since the endocannabinoids are water immiscible, protein transporters have been described that act as carriers to ... Is Readily Hydrolyzed in a Sterol-Modulated Fashion". ACS Chemical Neuroscience. 3 (5): 364-368. doi:10.1021/cn300001w. PMC ... Kaczocha, M.; Glaser, S.T.; Deutsch, D.G. (2009). "Identification of intracellular carriers for the endocannabinoid anandamide ...

The predominant sterol in fungal cell membranes is ergosterol. Sterols are steroids in which one of the hydrogen atoms is ... nuclear located protein kinase C and cyclic AMP-dependent protein kinase". Frontiers in Bioscience. 13 (13): 1206-1226. doi: ... Parodi AJ, Leloir LF (April 1979). "The role of lipid intermediates in the glycosylation of proteins in the eucaryotic cell". ... Helenius A, Aebi M (March 2001). "Intracellular functions of N-linked glycans". Science. 291 (5512): 2364-2369. Bibcode:2001Sci ...

These types of membranes differ in lipid and protein composition. Distinct types of membranes also create intracellular ... Peripheral proteins are unlike integral proteins in that they hold weak interactions with the surface of the bilayer and can ... In animal cells, membrane fluidity is modulated by the inclusion of the sterol cholesterol. This molecule is present in ... Comparison between lysine and guanidinium-rich carriers". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1848 (11, Part A ...

... sterol regulatory element-binding protein 1 and 2). In the presence of cholesterol, SREBP is bound to two other proteins: SCAP ... The main regulatory mechanism is the sensing of intracellular cholesterol in the endoplasmic reticulum by the protein SREBP ( ... LDL particles are the major blood cholesterol carriers. Each one contains approximately 1,500 molecules of cholesterol ester. ... The cleaved SREBP then migrates to the nucleus and acts as a transcription factor to bind to the sterol regulatory element (SRE ...

Amino acids are made into proteins by being joined in a chain of peptide bonds. Each different protein has a unique sequence of ... Steroids such as sterol are another major class of lipids. Carbohydrates are aldehydes or ketones, with many hydroxyl groups ... It also serves as a carrier of phosphate groups in phosphorylation reactions. A vitamin is an organic compound needed in small ... Wernegreen JJ (December 2005). "For better or worse: genomic consequences of intracellular mutualism and parasitism". Current ...

... gene expression can be regulated by sterol-response element binding proteins (SREBP-1/2), which also controls LDLR ... After being processed in the ER, PCSK9 co-localizes with the protein sortilin on its way through the Golgi and trans-Golgi ... The vaccine uses a VLP (virus-like particle) as an immunogenic carrier of an antigenic PCSK9 peptide. VLP's are viruses that ... in the intracellular space between keratinocytes. In addition to its likely role in epidermal lipid barrier formation, PCSK9 ...

... used in protein synthesis), and franesylated and geranylgeranylated proteins (membrane associated proteins that appear to be ... This pathway plays a key role in multiple cellular processes by synthesizing sterol isoprenoids, such as cholesterol, and non- ... carriers in the assembly of carbohydrate chains in glycoproteins), ubiquinones (important for electron transport), tRNA ... involved in intracellular signaling). The main point of regulation in cholesterol and nonsterol isoprene biosynethsis is HMGCoA ...

... s produce characteristic lipids and sterols. One of these sterols is typical of dinoflagellates and is called ... A specific carrier is shellfish. This can introduce both nonfatal and fatal illnesses. One such poison is saxitoxin, a powerful ... In place of histones, dinoflagellate nuclei contain a novel, dominant family of nuclear proteins that appear to be of viral ... The Dinophysoid dinoflagellates have two genera, Amphisolenia and Triposolenia, that contain intracellular cyanobionts, and ...

When compared with non-carriers, LDLR mutation carriers had higher plasma LDL cholesterol, whereas APOA5 mutation carriers had ... This protein belongs to the LDLR family and is made up of a number of functionally distinct domains, including 3 EGF-like ... Synthesis of receptors in the cell is regulated by the level of free intracellular cholesterol; if it is in excess for the ... Brown MS, Anderson RG, Goldstein JL (March 1983). "Recycling receptors: the round-trip itinerary of migrant membrane proteins ...

Gold DA, Grabenstatter J, de Mendoza A, Riesgo A, Ruiz-Trillo I, Summons RE (March 2016). "Sterol and genomic analyses validate ... A very large and internally consistent alignment of 1,719 proteins at the metazoan scale, published in 2017, showed that (i) ... engulfing and intracellular digestion). Particles from 0.5 μm to 50 μm are trapped in the ostia, which taper from the outer to ... which in most cases engulf the carrier and its cargo. A few species release fertilized eggs into the water, but most retain the ...