Interleukin
... 1 alpha and interleukin 1 beta (IL1 alpha and IL1 beta) are cytokines that participate in the regulation of immune ... Gately MK, Renzetti LM, Magram J, Stern AS, Adorini L, Gubler U, Presky DH (1998). "The interleukin-12/interleukin-12-receptor ... Recombinant expression enables cells to process precursor Interleukin 1 Beta to the mature form of the enzyme. Interleukin 1 ... di Giovine FS, Duff GW (Jan 1990). "Interleukin 1: the first interleukin". Immunology Today. 11 (1): 13-20. doi:10.1016/0167- ...
Interleukin 25
Interleukin-25 (IL-25) - also known as interleukin-17E (IL-17E) - is a protein that in humans is encoded by the IL25 gene on ... "Entrez Gene: IL25 interleukin 25". Moseley TA, Haudenschild DR, Rose L, Reddi AH (April 2003). "Interleukin-17 family and IL-17 ... April 2015). "Interleukin-17B Antagonizes Interleukin-25-Mediated Mucosal Inflammation". Immunity. 42 (4): 692-703. doi:10.1016 ... Angkasekwinai P, Park H, Wang YH, Wang YH, Chang SH, Corry DB, Liu YJ, Zhu Z, Dong C (July 2007). "Interleukin 25 promotes the ...
Interleukin 3
... is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease ... Tabira T, Chui DH, Fan JP, Shirabe T, Konishi Y (1998). "Interleukin-3 and interleukin-3 receptors in the brain". Ann. N. Y. ... Interleukin 3 has been shown to interact with IL3RA. Interleukin GRCh38: Ensembl release 89: ENSG00000164399 - Ensembl, May ... interleukin-3 (IL-3), and interleukin-5 (IL-5) receptor complexes to chromosome 22q13.1". Human Genetics. 93 (2): 198-200. doi: ...
Interleukin 11
As a signaling molecule, interleukin 11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; ... Interleukin 11 (IL-11 or adipogenesis inhibitory factor) is a protein that in humans is encoded by the IL11 gene. IL-11 is a ... Chen HF, Lin CY, Chao KH, Wu MY, Yang YS, Ho HN (May 2002). "Defective production of interleukin-11 by decidua and chorionic ... Interleukin 11 is manufactured using recombinant DNA technology.[citation needed] It is marketed as a protein therapeutic ...
Interleukin 16
... is a pro-inflammatory pleiotropic cytokine. It's precursor, pro-interleukin-16 is a protein that in humans is ... Interleukin 16 (IL-16) is released by a variety of cells (including lymphocytes and some epithelial cells) that has been ... Interleukin 16 has been shown to interact with: GRIN2A, GRIN2D, KCNJ10, KCNJ15, Kir2.1, PPP1R12A, and PPP1R12B. GRCh38: Ensembl ... "Entrez Gene: IL16 interleukin 16 (lymphocyte chemoattractant factor)". Cruikshank W, Center DM (June 1982). "Modulation of ...
Interleukin 6
... (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In ... Interleukin-6 has been shown to interact with interleukin-6 receptor, glycoprotein 130, and Galectin-3. There is considerable ... Other cytokines that signal through receptors containing gp130 are Interleukin 11 (IL-11), Interleukin 27 (IL-27), ciliary ... "Direct determination of the interleukin-6 binding epitope of the interleukin-6 receptor by NMR spectroscopy". The Journal of ...
Interleukin-38
... (IL-38) is a member of the interleukin-1 (IL-1) family and the interleukin-36 (IL-36) subfamily. It is important ... Jung, MY; Kang, SW; Kim, SK; Kim, H-J; Yun, DH; Yim, S-V; Hong, SJ; Chung, J-H (2010-02-09). "The interleukin-1 family gene ... Yuan, X. L.; Li, Y.; Pan, X. H.; Zhou, M.; Gao, Q. Y.; Li, M. C. (May 2016). "Production of recombinant human interleukin-38 ... Also serum levels of IL-17 and interleukin-22 were lower in these mice what approves in vitro observation that IL-38 could ...
Interleukin 28
Interleukin-28 (IL-28) is a cytokine that comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against ... 2004). "Interleukin-28 and 29 (IL-28 and IL-29): new cytokines with anti-viral activities". International Journal of ... Protein pages needing a picture, Genes on human chromosome 19, Interleukins). ...
Interleukin 13
Zurawski G, de Vries JE (January 1994). "Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but ... Interleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene. IL-13 was first cloned in 1993 and is located ... Interleukin-13 has a critical role in goblet cell metaplasia. Goblet cells are filled with mucin (MUC). MUC5AC Mucin 5AC is a ... October 2004). "Interleukin-13 in the skin and interferon-gamma in the liver are key players in immune protection in human ...
Interleukin 30
... (IL-30) forms one chain of the heterodimeric cytokine called interleukin 27 (IL-27), thus it is also called IL27 ... September 2006). "Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic ... Catalan-Dibene J, McIntyre LL, Zlotnik A (October 2018). "Interleukin 30 to Interleukin 40". Journal of Interferon & Cytokine ... Catalan-Dibene J, McIntyre LL, Zlotnik A (October 2018). "Interleukin 30 to Interleukin 40". Journal of Interferon & Cytokine ...
Interleukin 19
Interleukin-19 is a cytokine that belongs to the IL-10 family of cytokines along with several other interleukins including IL- ... Interleukin 19 (IL-19) is an immunosuppressive protein that belongs to the IL-10 cytokine subfamily. Human IL-19 is encoded by ... "IL19 interleukin 19 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2022-03-01. Leigh T, Scalia RG, ... 2011-11-15). "Interleukin-19: a constituent of the regulome that controls antigen presenting cells in the lungs and airway ...
Interleukin 24
... (IL-24) is a protein in the interleukin family, a type of cytokine signaling molecule in the immune system. In ... This interleukin is also known as melanoma differentiation-associated 7 (mda-7) due to its discovery as a tumour suppressing ... March 2016). "The interleukin-20 receptor axis in early rheumatoid arthritis: novel links between disease-associated ... Wang M, Tan Z, Zhang R, Kotenko SV, Liang P (March 2002). "Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric ...
Interleukin 9
... , also known as IL-9, is a pleiotropic cytokine (cell signalling molecule) belonging to the group of interleukins ... Renauld J (1995). "Interleukin-9: Structural characteristics and biologic properties". Cytokines: Interleukins and Their ... Interleukin 33 (IL-33) induces IL-9 expression and secretion in T cells, which was confirmed by the results obtained in mice by ... Interleukin-9 has also shown to inhibit melanoma growth in mice. Additionally, it gives rise to the multiplication of ...
Interleukin 29
Interleukin-29 (IL-29) is a cytokine and it belongs to type III interferons group, also termed interferons λ (IFN-λ). IL-29 ( ... "Entrez Gene: interleukin 29 (interferon". Wang JM, Huang AF, Xu WD, Su LC (December 2019). "Insights into IL-29: Emerging role ... Pagliaccetti NE, Eduardo R, Kleinstein SH, Mu XJ, Bandi P, Robek MD (October 2008). "Interleukin-29 functions cooperatively ... Articles with short description, Short description matches Wikidata, Genes on human chromosome 19, Interleukins, Cytokines, ...
Interleukin 37
Interleukin-1 family Interleukin 18 Interleukin 18 receptor Interleukin 18 binding protein Inflammation Carcinogenesis GRCh38: ... Interleukin 37 (IL-37), also known as Interleukin-1 family member 7 (IL-1F7), is an anti-inflammatory cytokine important for ... April 2018). "The Role, Involvement and Function(s) of Interleukin-35 and Interleukin-37 in Disease Pathogenesis". ... interleukin-1 beta, and interleukin-1 receptor antagonist genes". Genomics. 19 (2): 382-384. doi:10.1006/geno.1994.1076. PMID ...
Interleukin 15
Together with Interleukin-2 (IL-2), Interleukin-4 (IL-4), Interleukin-7 (IL-7), Interleukin-9 (IL-9), granulocyte colony- ... February 2014). "Identification of a gene for an ancient cytokine, interleukin 15-like, in mammals; interleukins 2 and 15 co- ... Liew FY, McInnes IB (November 2002). "Role of interleukin 15 and interleukin 18 in inflammatory response". Annals of the ... December 2007). "Crystal Structure of the interleukin-15.interleukin-15 receptor alpha complex: insights into trans and cis ...
Interleukin 7
"Entrez Gene: IL7 interleukin 7". Noguchi M, Nakamura Y, Russell SM, et al. (1994). "Interleukin-2 receptor gamma chain: a ... Aspinall R, Henson S, Pido-Lopez J, Ngom PT (2004). "Interleukin-7: an interleukin for rejuvenating the immune system". Ann. N ... "Human follicular dendritic cells and vascular cells produce interleukin-7: a potential role for interleukin-7 in the germinal ... Interleukin 7 (IL-7) is a protein that in humans is encoded by the IL7 gene. IL-7 is a hematopoietic growth factor secreted by ...
Interleukin 32
... (IL32) is proinflammatory cytokine that in humans is encoded by the IL32 gene. Interleukin 32 can be found in ... "Entrez Gene: Interleukin 32". Sloot YJ, Smit JW, Joosten LA, Netea-Maier RT (August 2018). "Insights into the role of IL-32 in ... Interleukin 32 (IL-32) is a pro-inflammatory cytokine that can induce cells of the immune system (such as monocytes and ... Interleukin 32 is connected with several diseases, including cancer. This gene encodes a member of the cytokine family. The ...
Interleukin 23
February 2003). "Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain". ... Cauli A, Piga M, Floris A, Mathieu A (2015-10-01). "Current perspective on the role of the interleukin-23/interleukin-17 axis ... Interleukin 23 (IL-23) is a heterodimeric cytokine composed of an IL-12B (IL-12p40) subunit (which is shared with IL-12) and an ... March 2013). "Interleukin 23 regulates proliferation of lung cancer cells in a concentration-dependent way in association with ...
Interleukin 18
Interleukin-18 (IL-18), also known as interferon-gamma inducing factor is a protein which in humans is encoded by the IL18 gene ... Liu Z, Wang H, Xiao W, Wang C, Liu G, Hong T (October 2010). "Thyrocyte interleukin-18 expression is up-regulated by interferon ... This interleukin was also significantly elevated in patients with microalbuminuria and macroalbuminuria when it was compared ... Nolan KF, Greaves DR, Waldmann H (July 1998). "The human interleukin 18 gene IL18 maps to 11q22.2-q22.3, closely linked to the ...
Interleukin 26
"The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor ... Interleukin-26 (IL-26) is a protein that in humans is encoded by the IL26 gene. IL-26 is the most recently identified member of ... Interleukin 26 (IL-26) is an inflammatory mediator and a driver of chronic inflammation due to its ability to act as a carrier ... "Entrez Gene: interleukin 26". Knappe A, Hör S, Wittmann S, Fickenscher H (April 2000). "Induction of a novel cellular homolog ...
Interleukin 21
... (IL-21) is a protein that in humans is encoded by the IL21 gene. Interleukin-21 is a cytokine that has potent ... "Entrez Gene: IL21 interleukin 21". Parrish-Novak J, Foster DC, Holly RD, Clegg CH (November 2002). "Interleukin-21 and the IL- ... Interleukin-21 is also produced by Hodgkin's lymphoma (HL) cancer cells (which is surprising because IL-21 was thought to be ... Zhang SQ, Chen B, Luo X, Xu CZ (July 2004). "[Cloning and expression of human interleukin-21 cDNA in E.coli]". Xi Bao Yu Fen Zi ...
Interleukin 31
Interleukin-31 (IL-31) is a protein that in humans is encoded by the IL31 gene that resides on chromosome 12. IL-31 is an ... "Entrez Gene: interleukin 31". Dillon SR, Sprecher C, Hammond A, Bilsborough J, Rosenfeld-Franklin M, Presnell SR, et al. (July ... Interleukin 31 is an inflammatory cytokine produced by activated CD4+ T lymphocytes, in particular activated TH2 helper cells, ... The receptor for IL-31 is a heterodimer of the interleukin 31 receptor alpha (IL-31RA) and OSMR. IL-31RA was originally ...
Interleukin 36
"IL36B interleukin 36 beta [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2022-09-09. "IL36G interleukin ... Interleukin 36, or IL-36, is a group of cytokines in the IL-1 family with pro-inflammatory effects. The role of IL-36 in ... "IL36A interleukin 36 alpha [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2022-09-09. " ... Towne, Jennifer E.; Garka, Kirsten E.; Renshaw, Blair R.; Virca, G. Duke; Sims, John E. (2004-04-02). "Interleukin (IL)-1F6, IL ...
Interleukin 33
... (IL-33) is a protein that in humans is encoded by the IL33 gene. Interleukin 33 is a member of the IL-1 family ... Interleukin 33 (IL-33) is a cytokine belonging to the IL-1 superfamily. IL-33 induces helper T cells, mast cells, eosinophils ... "Entrez Gene: Interleukin 33". Yagami A, Orihara K, Morita H, Futamura K, Hashimoto N, Matsumoto K, et al. (November 2010). "IL- ... Casciaro M, Cardia R, Di Salvo E, Tuccari G, Ieni A, Gangemi S (May 2019). "Interleukin-33 Involvement in Nonsmall Cell Lung ...
Interleukin 17F
... interleukin 1, interleukin 6 and some members of the colony-stimulating factor family. IL-17F can also induce expression of ... Interleukin 17F (IL-17F) is signaling protein that is in human is encoded by the IL17F gene and is considered a pro- ... The interleukin 17 family members are among the effector cytokines of Th17 immune response. This immune response protects hosts ... IL-17F is highly (55%) homologous to interleukin-17A (IL-17A). These two molecules bind to the same receptors and are very ...
Interleukin 22
Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A (2001). "Interleukin-10 and the interleukin-10 receptor". Annual Review of ... Interleukin-22 (IL-22) is protein that in humans is encoded by the IL22 gene. IL-22 is an α-helical cytokine. IL-22 binds to a ... October 2000). "Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2- ... Pestka S, Krause CD, Sarkar D, Walter MR, Shi Y, Fisher PB (2004). "Interleukin-10 and related cytokines and receptors". Annual ...
Interleukin 5
... (IL-5) is an interleukin produced by type-2 T helper cells and mast cells. Through binding to the interleukin-5 ... The α subunit is specific for the IL-5 molecule, whereas the βc subunit also recognised by interleukin 3 (IL-3) and granulocyte ... Unlike other members of this cytokine family (namely interleukin 3 and GM-CSF), this glycoprotein in its active form is a ... Overview of all the structural information available in the PDB for UniProt: P05113 (Interleukin-5) at the PDBe-KB. (CS1: long ...
Interleukin 27
... (IL-27) is a member of the IL-12 cytokine family. It is a heterodimeric cytokine that is encoded by two distinct ... Iwasaki Y, Fujio K, Okamura T, Yamamoto K (January 2015). "Interleukin-27 in T cell immunity". International Journal of ... Yoshida H, Hunter CA (April 2015). "The immunobiology of interleukin-27". Annual Review of Immunology. 33 (1): 417-43. doi: ... Aparicio-Siegmund S, Garbers C (October 2015). "The biology of interleukin-27 reveals unique pro- and anti-inflammatory ...
Interleukin 34
... (IL-34) is a protein belonging to a group of cytokines called interleukins. It was originally identified in ... Interleukin-34 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Articles with short description ... Overview of all the structural information available in the PDB for UniProt: Q6ZMJ4 (Human Interleukin-34) at the PDBe-KB. ... Overview of all the structural information available in the PDB for UniProt: Q8R1R4 (Mouse Interleukin-34) at the PDBe-KB. ...