... interleukin-1 beta, interleukin-6 and interleukin-8 in the pathogenesis of the otitis media with effusion". Eur. Cytokine Netw ... Interleukin 8 (IL-8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types ... In humans, the interleukin-8 protein is encoded by the CXCL8 gene. IL-8 is initially produced as a precursor peptide of 99 ... Interleukin-8 is a key mediator associated with inflammation where it plays a key role in neutrophil recruitment and neutrophil ...
Binding of Interleukin 8 leads to activation of the cell (commonly a neutrophil), allowing it to recruit more white blood cells ... The interleukin-8 receptors (IL-8R) are two 7-transmembrane proteins in the G-protein coupled-receptor family: interleukin-8 ... Receptors,+Interleukin-8 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Protein pages needing a ... IL-8RA is highly specific for interleukin-8 and only responds when this particular ligand is bound to its receptor site, ...
Interleukin Interleukin 8 Interleukin 8 receptor, beta Interleukin receptor Interleukin-8 receptor GRCh38: Ensembl release 89: ... Interleukin 8 receptor, alpha is a chemokine receptor. This name and the corresponding gene symbol IL8RA have been replaced by ... "Entrez Gene: IL8RA interleukin 8 receptor, alpha". Bergin DA, Reeves EP, Meleady P, Henry M, McElvaney OJ, Carroll TP, Condron ... This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G- ...
... is a chemokine receptor. IL8RB is also known as CXCR2, and CXCR2 is now the IUPHAR Committee on ... "Entrez Gene: IL8RB interleukin 8 receptor, beta". Auer PL, Teumer A, Schick U, O'Shaughnessy A, Lo KS, Chami N, Carlson C, de ... This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G- ... Lee J, Horuk R, Rice GC, Bennett GL, Camerato T, Wood WI (Aug 1992). "Characterization of two high affinity human interleukin-8 ...
... 1 alpha and interleukin 1 beta (IL1 alpha and IL1 beta) are cytokines that participate in the regulation of immune ... Gately MK, Renzetti LM, Magram J, Stern AS, Adorini L, Gubler U, Presky DH (1998). "The interleukin-12/interleukin-12-receptor ... Recombinant expression enables cells to process precursor Interleukin 1 Beta to the mature form of the enzyme. Interleukin 1 ... di Giovine FS, Duff GW (Jan 1990). "Interleukin 1: the first interleukin". Immunology Today. 11 (1): 13-20. doi:10.1016/0167- ...
... interleukin 1, interleukin 6 and some members of the colony-stimulating factor family. IL-17F can also induce expression of ... Interleukin 17F (IL-17F) is signaling protein that is in human is encoded by the IL17F gene and is considered a pro- ... The interleukin 17 family members are among the effector cytokines of Th17 immune response. This immune response protects hosts ... IL-17F is highly (55%) homologous to interleukin-17A (IL-17A). These two molecules bind to the same receptors and are very ...
Interleukin 5), promote adaptive and allergic immune responses (viz., Interleukin 4), promote allergic responses and tissue ... interleukin 5 and annexin A1). DRESS syndrome: Key elements promoting tissue injury in the DRESS syndrome are: Th2 cells and ... Interleukin 22); and a cytokine which promotes the function of neutrophils, other granulocyte types, and monocytes as well as ... Interleukin 8 and Interleukin 17); a promoter of innate immune and autoimmune responses (viz., ...
... interleukin-6, interleukin-8, and GM-CSF. These activities are G2A-dependent. It is suggested that 9-HODE acts in human skin to ... interleukin-6 and keratinocyte chemoattractant, for in vivo studies. G2A is also involved in blood-borne ... 178 (10): 6540-8. doi:10.4049/jimmunol.178.10.6540. PMID 17475884. Yan JJ, Jung JS, Lee JE, Lee J, Huh SO, Kim HS, Jung KC, Cho ... doi:10.1016/S0021-9258(19)47942-8. PMID 16498716. Lan W, Yamaguchi S, Yamamoto T, Yamahira S, Tan M, Murakami N, Zhang J, ...
... (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In ... Interleukin-6 has been shown to interact with interleukin-6 receptor, glycoprotein 130, and Galectin-3. There is considerable ... Other cytokines that signal through receptors containing gp130 are Interleukin 11 (IL-11), Interleukin 27 (IL-27), ciliary ... "Direct determination of the interleukin-6 binding epitope of the interleukin-6 receptor by NMR spectroscopy". The Journal of ...
October 1994). "Histamine induces interleukin-8 secretion by endothelial cells". Blood. 84 (7): 2229-2233. doi:10.1182/blood. ... the C314T variant also showed an association with serum Interleukin-8 (IL-8) levels - individuals with the CT or TT genotype ... Although the relationship between histamine and IL-8 has not been fully studied as of 2020[update], it is known that histamine ... had lower levels of IL-8 (1.2 ± 0.7 versus 2.1) and higher levels of histamine (107.0 ± 53.9 versus 85.6 ± 45.7 ng/mL) in ...
Interleukin-8 plays a role in rheumatoid arthritis. Protease secretion: Blastocystis secretes a protease that breaks up ... Blastocystis has been shown to provoke cells from the human colon to produce inflammatory cytokines interleukin-8 and GM-CSF. ... 46 (8): 178-9. PMID 8936976. Khalifa AM, El Temsahy MM, Abou El Naga IF (2001). "Effect of ozone on the viability of some ... 39 (4): 734-8. Bibcode:1980ApEnM..39..734L. doi:10.1128/AEM.39.4.734-738.1980. PMC 291411. PMID 7377773. Li LH; Zhou XN; Du ZW ...
... has been shown to interact with: EYA2, GPSM2, Interleukin 8 receptor, alpha, MDFI, RGS5, and RIC8A. GRCh38: Ensembl ... Damaj BB, McColl SR, Mahana W, Crouch MF, Naccache PH (May 1996). "Physical association of Gi2alpha with interleukin-8 ... "Identification of G-protein binding sites of the human interleukin-8 receptors by functional mapping of the intracellular loops ... 266 (6): 3365-8. doi:10.1016/S0021-9258(19)67799-9. PMID 1671672. Cormont M, Le Marchand-Brustel Y, Van Obberghen E, Spiegel AM ...
Wu D, LaRosa GJ, Simon MI (Jul 1993). "G protein-coupled signal transduction pathways for interleukin-8". Science. 261 (5117): ... 93 (12): 6053-8. Bibcode:1996PNAS...93.6053S. doi:10.1073/pnas.93.12.6053. PMC 39187. PMID 8650218. Zhang J, Pratt RE (Jun 1996 ... 93 (26): 15203-8. Bibcode:1996PNAS...9315203D. doi:10.1073/pnas.93.26.15203. PMC 26381. PMID 8986788. Woulfe DS, Stadel JM (Jun ... doi:10.1016/s0898-6568(02)00012-8. PMID 11955952. De Vries L, Elenko E, Hubler L, Jones TL, Farquhar MG (Dec 1996). "GAIP is ...
"A physical map of the region encompassing the human interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor ... Interleukin-36 beta also known as interleukin-1 family member 8 (IL1F8) is a protein that in humans is encoded by the IL36B ... 2004). "Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF- ... Mulero JJ, Pace AM, Nelken ST, Loeb DB, Correa TR, Drmanac R, Ford JE (Nov 1999). "IL1HY1: A novel interleukin-1 receptor ...
Interleukin-25 (IL-25) - also known as interleukin-17E (IL-17E) - is a protein that in humans is encoded by the IL25 gene on ... "Entrez Gene: IL25 interleukin 25". Moseley TA, Haudenschild DR, Rose L, Reddi AH (April 2003). "Interleukin-17 family and IL-17 ... April 2015). "Interleukin-17B Antagonizes Interleukin-25-Mediated Mucosal Inflammation". Immunity. 42 (4): 692-703. doi:10.1016 ... Angkasekwinai P, Park H, Wang YH, Wang YH, Chang SH, Corry DB, Liu YJ, Zhu Z, Dong C (July 2007). "Interleukin 25 promotes the ...
In these cases Interleukin-8 is a risk for clinical conversion. It has also been proposed that always exists a subclinical ... 11 (8): 471-482. doi:10.1038/nrneurol.2015.106. PMID 26149978. Mistry N, Dixon J, Tallantyre E, Tench C, Abdel-Fahim R, Jaspan ... 8: 234. doi:10.3389/fneur.2017.00234. PMC 5449443. PMID 28620346. Acquaviva M, Bassani C, Sarno N, Dalla Costa G, Romeo M, ... 15 (8): 858-861. doi:10.1111/j.1468-1331.2008.02155.x. PMID 18507677. S2CID 27212599. Lebrun C, Bensa C, Debouverie M, De Seze ...
"Cloning of Complementary DNA Encoding a Functional Human Interleukin-8 Receptor." Science (American Association for the ... 8 (1): e1364. doi:10.1002/wrna.1364. ISSN 1757-7004. PMC 5717752. PMID 27198714. Liptak, Adam (13 June 2013). "Supreme Court ... doi:10.1186/s12896-014-0094-8. ISSN 1472-6750. PMC 4239376. PMID 25394494. "mRNA Isolation with Dynabeads in 15 minutes - US". ...
Additionally, neutrophil apoptosis, immunoglobulin release from B-lymphocytes, and interleukin release (e.g. IL-8 and CCL5) are ... Denning G, Wollenweber L, Railsback M, Cox C, Stoll L, Britigan B (1998). "Pseudomonas pyocyanin increases interleukin-8 ...
... and published scientific articles on the localisation of gene expression for interleukin 1 receptor antagonist, interleukin 1 ... Wong, M.-L.; Bongiorno, P. B.; Rettori, V.; McCann, S. M.; Licinio, J.; Wong, M.-L. (7 January 1997). "Interleukin (IL) 1beta, ... Licinio, J.; Wong, M.-L.; Gold, P. W. (July 1991). "Localization of interleukin-1 receptor antagonist mRNA in rat brain". ... They also showed that interleukin 1 receptor antagonist is an endogenous neuroprotective agent. They have shown that the ...
May 2004). "Elevated maternal interleukin-8 levels and risk of schizophrenia in adult offspring". The American Journal of ... Interleukin 8). Substantial research suggests that exposure to certain illnesses (e.g., influenza) in the mother of a fetus ( ... 32 (1): 3-8. doi:10.1093/schbul/sbj028. PMC 2632192. PMID 16306181. Opler, M. G.; Brown, A. S.; Graziano, J.; Desai, M.; Zheng ... 163 (3): 521-8. doi:10.1176/appi.ajp.163.3.521. PMID 16513876. Jones AL, Mowry BJ, Pender MP, Greer JM (February 2005). "Immune ...
... has a potentially similar role as interleukin-8 (IL-8/CXCL8). After binding to its receptor CXCR2, CXCL1 activates ... cells were stimulated with interleukin-1β (IL-1β) and lipopolysaccharide (LPS) to generate a cytokine that was chemotactic for ... and low-affinity binding of GRO alpha and neutrophil-activating peptide 2 to interleukin 8 receptors on human neutrophils". ... 19 (8): 2427. doi:10.3390/ijms19082427. PMC 6121631. PMID 30115896. Spaks A (April 2017). "Role of CXC group chemokines in lung ...
"We have to check that," he said and discovered a new protein, interleukin-8, around 13 years ago. It was the first of more than ... "Das müssen wir checken" sagte er und entdeckte vor rund 13 Jahren ein neues Protein, das Interleukin-8. Es war das erste von ... Baggiolini, Marco; Dewald, Beatrice; Moser, Bernhard (1989). "Neutrophil-activating peptide-1/interleukin 8, a novel cytokine ... Baggiolini, Marco; Dewald, Beatrice; Moser, Bernhard (1993). lnterleukin-8 and related chemotactic cytokines-CXC and CC ...
"Post-transcriptional modulation of interleukin 8 by CNOT6L regulates skeletal muscle differentiation". Biochim. Biophys. Acta. ... 16 (7-8): 247-53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614. Wang H, Morita M, Yang X, Suzuki T, Yang W, Wang J ... 590 (8): 1270-9. doi:10.1002/1873-3468.12160. PMID 27013054. Morita M, Siddiqui N, Katsumura S, Rouya C, Larsson O, Nagashima T ...
"Relationship between cervical mucus interleukin-8 concentrations and vaginal bacteria in pregnancy". American Journal of ... 84 (8): 734-742. doi:10.1111/j.0001-6349.2005.00525.x. PMID 16026397. S2CID 20962823. Critchfield AS, Yao G, Jaishankar A, ... It also lead to increased cervical mucus IL-8 and increased preterm birth. Dysbiosis occurs when the presence of naturally ... 8 (8): e69528. Bibcode:2013PLoSO...869528C. doi:10.1371/journal.pone.0069528. PMC 3731331. PMID 23936335. Santella, Biagio; ...
"Interleukin-8 and polymorphoneutrophil leucocyte activation in hemolytic uremic syndrome of childhood". Kidney International. ... 75 (8): 848-855. doi:10.1038/ki.2008.686. PMC 2813773. PMID 19165178. Fizpatrick, Margaret M.; Walters, Martin D.S.; Trompeter ... doi:10.1007/s00467-014-2805-8. ISSN 1432-198X. PMID 24682468. Levin, Michael (3 February 2014). "Martin Barratt obituary". ...
Loomis WH, Namiki S, Ostrom RS, Insel PA, Junger WG (Feb 2003). "Hypertonic stress increases T cell interleukin-2 expression ... "Human neutrophil peptides induce interleukin-8 production through the P2Y6 signaling pathway". Blood. 107 (7): 2936-42. doi: ... 222 (2): 303-8. doi:10.1006/bbrc.1996.0739. PMID 8670200. "Entrez Gene: P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 ...
... is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease ... Tabira T, Chui DH, Fan JP, Shirabe T, Konishi Y (1998). "Interleukin-3 and interleukin-3 receptors in the brain". Ann. N. Y. ... Interleukin 3 has been shown to interact with IL3RA. Interleukin GRCh38: Ensembl release 89: ENSG00000164399 - Ensembl, May ... interleukin-3 (IL-3), and interleukin-5 (IL-5) receptor complexes to chromosome 22q13.1". Human Genetics. 93 (2): 198-200. doi: ...
As a signaling molecule, interleukin 11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; ... Interleukin 11 (IL-11 or adipogenesis inhibitory factor) is a protein that in humans is encoded by the IL11 gene. IL-11 is a ... Chen HF, Lin CY, Chao KH, Wu MY, Yang YS, Ho HN (May 2002). "Defective production of interleukin-11 by decidua and chorionic ... Interleukin 11 is manufactured using recombinant DNA technology.[citation needed] It is marketed as a protein therapeutic ...
... is a pro-inflammatory pleiotropic cytokine. It's precursor, pro-interleukin-16 is a protein that in humans is ... Interleukin 16 (IL-16) is released by a variety of cells (including lymphocytes and some epithelial cells) that has been ... Interleukin 16 has been shown to interact with: GRIN2A, GRIN2D, KCNJ10, KCNJ15, Kir2.1, PPP1R12A, and PPP1R12B. GRCh38: Ensembl ... "Entrez Gene: IL16 interleukin 16 (lymphocyte chemoattractant factor)". Cruikshank W, Center DM (June 1982). "Modulation of ...
... (IL-38) is a member of the interleukin-1 (IL-1) family and the interleukin-36 (IL-36) subfamily. It is important ... Jung, MY; Kang, SW; Kim, SK; Kim, H-J; Yun, DH; Yim, S-V; Hong, SJ; Chung, J-H (2010-02-09). "The interleukin-1 family gene ... Yuan, X. L.; Li, Y.; Pan, X. H.; Zhou, M.; Gao, Q. Y.; Li, M. C. (May 2016). "Production of recombinant human interleukin-38 ... Also serum levels of IL-17 and interleukin-22 were lower in these mice what approves in vitro observation that IL-38 could ...