... , is a subunit of the interleukin-20 receptor, the interleukin-26 receptor, and the ... The interleukin 20 receptor, alpha subunit is also referred to as IL20R1 or IL20RA. The IL20RA receptor is involved in both pro ... "The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor ... IL20RA, along with the IL-20 receptor, beta subunit, form the heterodimeric interleukin-20 receptor, which binds the cytokines ...

Interleukin 27 receptor, alpha is a subunit of the interleukin-27 receptor. IL27RA is its human gene. In mice, CD4+ helper T- ... Interleukin 27 receptor, alpha subunit has been shown to interact with STAT1. ENSG00000288185 GRCh38: Ensembl release 89: ... "Entrez Gene: IL27RA interleukin 27 receptor, alpha". Takeda A, Hamano S, Yamanaka A, Hanada T, Ishibashi T, Mak TW, Yoshimura A ... This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is ...

... is a subunit for the interleukin-10 receptor. IL10RA, is its human gene. IL10RA has also ... Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Interleukin 10 receptor, alpha subunit ... IL10RA interleukin 10 receptor, alpha". Ho AS, Liu Y, Khan TA, Hsu DH, Bazan JF, Moore KW (December 1993). "A receptor for ... Ho AS, Liu Y, Khan TA, Hsu DH, Bazan JF, Moore KW (1994). "A receptor for interleukin 10 is related to interferon receptors". ...

... is a subunit of the interleukin 15 receptor that in humans is encoded by the IL15RA gene ... The IL-15 receptor is composed of three subunits: IL-15R alpha, CD122, and CD132. Two of these subunits, CD122 and CD132, are ... "IL-2 and IL-15 receptor alpha-subunits are coexpressed in a supramolecular receptor cluster in lipid rafts of T cells". Proc. ... shared with the receptor for IL-2, but IL-2 receptor has an additional subunit (CD25). The shared subunits contain the ...

Interleukin 11 receptor, alpha subunit is a subunit of the interleukin 11 receptor. IL11RA is its human gene. Interleukin 11 is ... "Entrez Gene: IL11RA interleukin 11 receptor, alpha". Chérel M, Sorel M, Lebeau B, et al. (1995). "Molecular cloning of two ... 2007). "Expression of interleukin-11 (IL-11) and IL-11 receptor alpha in human gastric carcinoma and IL-11 upregulates the ... 1996). "The human interleukin-11 receptor alpha gene (IL11RA): genomic organization and chromosome mapping". Genomics. 32 (1): ...

Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 ... Interleukin 5 receptor alpha subunit has been shown to interact with: Interleukin 5, Janus kinase 2, Protein unc-119 homolog, ... The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for ... Interleukin-5 receptor subunit alpha) at the PDBe-KB. This article incorporates text from the United States National Library of ...

Type 2 receptors consist of an IL-4Rα subunit bound to a different subunit known as IL-13Rα1. These type 2 receptors have the ... "The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor". The New England ... This receptor exists in 3 different complexes throughout the body. Type 1 receptors are composed of the IL-4Rα subunit with a ... The receptor for interleukin-4 is known as the IL-4Rα. ... Interleukin-4 at the U.S. National Library of Medicine Medical ...

... binds to the alpha subunit of the interleukin-4 receptor (IL-4Rα), making it a receptor antagonist. Through blockade ... Dupilumab, sold under the brand name Dupixent, is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for ... dupilumab modulates signaling of both the interleukin 4 and interleukin 13 pathways. Dupilumab shows a non-linear rate in ... Retrieved 4 May 2022. "Dupixent- dupilumab injection, solution". DailyMed. 25 June 2020. Archived from the original on 24 March ...

... forming the type II IL4 receptor). This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane ... It is a heterodimer, that is, composed of two subunits. IL4R is the human gene coding for IL-4Rα, the subunit which combines ... Interleukin-4 receptor has been shown to interact with SHC1. The N-terminal (extracellular) portion of interleukin-4 receptor ... They are required for binding of interleukin-4 to the receptor alpha chain, which is a crucial event for the generation of a ...

It is a heterodimer composed of the interleukin 27 receptor, alpha subunit and glycoprotein 130. IL27RA essential for ... The interleukin-27 receptor is a type I cytokine receptor for interleukin-27. ... Receptors,+Interleukin-27 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Articles with short ... "Cloning and characterization of a novel class I cytokine receptor". Biochem. Biophys. Res. Commun. 246 (1): 82-90. doi:10.1006/ ...

The interleukin-5 receptor is a type I cytokine receptor. It is a heterodimer of the interleukin 5 receptor alpha subunit and ... "JAK2 and JAK1 constitutively associate with an interleukin-5 (IL-5) receptor alpha and betac subunit, respectively, and are ... In fact, the β-subunit of the IL-5 receptor is also found in IL-3 and GM-CSF receptors where it is associated with IL-3Rα and ... Therefore, it is known as the common β receptor or βc. As with the IL-5Rα subunit, the β subunit's cytoplasmic domain is ...

This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves ... Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1), is a human gene. The ... "Entrez Gene: IL13RA1 interleukin 13 receptor, alpha 1". Kornau HC, Schenker LT, Kennedy MB, Seeburg PH (1995). "Domain ... Orchansky PL, Kwan R, Lee F, Schrader JW (1999). "Characterization of the cytoplasmic domain of interleukin-13 receptor-alpha ...

"Genetic variations in the interleukin-12/interleukin-23 receptor (beta1) chain, and implications for IL-12 and IL-23 receptor ... Interleukin-23 (IL-23) is a heterodimeric cytokine composed of an Interleukin 23 alpha subunit and an IL-12p40 subunit. The IL- ... Interleukin-23 subunit alpha is a protein that in humans is encoded by the IL23A gene. The protein is also known as IL-23p19. ... "Entrez Gene: IL23A interleukin 23, alpha subunit p19". Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, et al. ( ...

G-protein-coupled receptor kinase 2) D2 dopamine receptor IL1RAPL1 (interleukin-1 receptor accessory protein-like 1 protein) ... alpha}1-subunit co-regulate synaptic transmission and nerve-terminal growth". Journal of Cell Science. 122 (22): 4109-4121. doi ... NCS-1 is a globular protein consisting of ten alpha-helices. Four pairs of alpha-helices each form independent 12-amino-acid ... It is the Ca2+-sensing subunit of the yeast phosphatidylinositol (PtdIns)-4-OH kinase, PIK1 It binds to many proteins, some in ...

1998). "Heteromerization of the gammac chain with the interleukin-9 receptor alpha subunit leads to STAT activation and ... 2000). "14-3-3zeta interacts with the alpha-chain of human interleukin 9 receptor". Biochem. J. 345 (3): 741-7. doi:10.1042/ ... 1999). "Tip60 interacts with human interleukin-9 receptor alpha-chain". Biochem. Biophys. Res. Commun. 263 (1): 149-55. doi: ... Interleukin 9 receptor (IL9R) also known as CD129 (Cluster of Differentiation 129) is a type I cytokine receptor. IL9R also ...

"JAK2 and JAK1 constitutively associate with an interleukin-5 (IL-5) receptor alpha and betac subunit, respectively, and are ... "Physical interaction between interleukin-12 receptor beta 2 subunit and Jak2 tyrosine kinase: Jak2 associates with cytoplasmic ... the GM-CSF receptor family (IL-3R, IL-5R and GM-CSF-R), the gp130 receptor family (e.g., IL-6R), and the single chain receptors ... "Interaction of Janus kinases JAK-1 and JAK-2 with the insulin receptor and the insulin-like growth factor-1 receptor". ...

Milatovich A, Kitamura T, Miyajima A, Francke U (1993). "Gene for the alpha-subunit of the human interleukin-3 receptor (IL3RA ... The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for ... "Structure of the gene encoding the alpha subunit of the human interleukin 3 receptor". Biochem. Biophys. Res. Commun. 208 (1): ... "Entrez Gene: IL3RA interleukin 3 receptor, alpha (low affinity)". Stomski FC, Sun Q, Bagley CJ, Woodcock J, Goodall G, Andrews ...

... and alpha Interleukin-13 receptor (IL-13R1). The high affinity of IL-13 to the IL-13R1 leads to their bond formation which ... Interleukin-13 and its associated receptors with α subunit of the IL-4 receptor (IL-4Rα) allows for the downstream activation ... Interleukin-13 receptor, the IL-13 receptor GRCm38: Ensembl release 89: ENSMUSG00000020383 - Ensembl, May 2017 "Human PubMed ... This receptor is a heterodimer receptor complex consisting of alpha IL-4 receptor (IL-4Rα) ...

Interleukin-7 receptor subunit alpha (IL7R-α) also known as CD127 (Cluster of Differentiation 127) is a protein that in humans ... Overview of all the structural information available in the PDB for UniProt: P16872 (Mouse Interleukin-7 receptor subunit alpha ... IL7R-α is a type I cytokine receptor and is a subunit of the functional Interleukin-7 receptor and Thymic Stromal Lymphopoietin ... Human Interleukin-7 receptor subunit alpha) at the PDBe-KB. ... 1992). "The interleukin-7 receptor gene is at 5p13". Hum. Genet ...

... made up of the IL-20 receptor alpha subunit and beta subunit, and Type II, made up of the IL-22 receptor and IL-20 receptor ... IL20R alpha and beta subunits have also been found in some immune cells. IL20R is implicated in diseases such as psoriasis, ... Interleukin 20 receptors (IL20R) belong to the IL-10 family. IL20R are involved in both pro-inflammatory and anti-inflammatory ... Receptors,+Interleukin-20 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Protein pages needing a ...

Interleukin-13 receptor subunit alpha-2 (IL-13Rα2), also known as CD213A2 (cluster of differentiation 213A2), is a membrane ... Interleukin-13 receptor subunit alpha-2) at the PDBe-KB. This article incorporates text from the United States National Library ... "Entrez Gene: IL13RA2 interleukin 13 receptor, alpha 2". Fujisawa T, Joshi B, Nakajima A, Puri RK (November 2009). "A novel role ... IL-13Rα2 is closely related to IL-13Rα1, a subunit of the interleukin-13 receptor complex. This protein binds IL13 with high ...

The interleukin 28 receptor consists of an interleukin-28R alpha chain (IL-28RA) and another receptor, the beta subunit of the ... It consists of an α chain and shares a common β subunit with the interleukin-10 receptor. Binding to the interleukin-28 ... Interleukin-28 receptor is a type II cytokine receptor found largely in epithelial cells. It binds type 3 interferons, ... While the type 1 interferon receptor is diversely distributed, the Interleukin-28 receptor expression is more restricted, ...

The human protein Interleukin-2 receptor subunit alpha is encoded by a gene called IL2RA with a length around 51,6 kb. ... "IL2RA interleukin 2 receptor subunit alpha [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2023-01-25. ... Interleukin-2 receptor subunit alpha) at the PDBe-KB. (CS1: long volume value, Articles with short description, Short ... Interleukin-2 receptor alpha chain (also called TAC antigen, P55 and mainly CD25) is a protein involved in assembly of high- ...

... has been shown to interact with: EYA2, GPSM2, Interleukin 8 receptor, alpha, MDFI, RGS5, and RIC8A. GRCh38: Ensembl ... alpha i-G alpha s chimeras define the function of alpha chain domains in control of G protein activation and beta gamma subunit ... "Identification of G protein alpha-subunits in RINm5F cells and their selective interaction with galanin receptor". Diabetes. 40 ... "Distribution of the alpha-subunit of the guanine nucleotide-binding protein Gi2 and its comparison to G alpha o". Journal of ...

... interleukin 6, interleukin-12 subunit alpha, and interleukin-12 subunit beta; and mouse helper and cytotoxic T cells from ... Free fatty acid receptor Free fatty acid receptor 1 (CS1: long volume value, Articles with short description, Short description ... "Identification of G-protein-coupled receptor 120 as a tumor-promoting receptor that induces angiogenesis and migration in human ... Free Fatty acid receptor 4 (FFAR4), also termed G-protein coupled receptor 120 (GPR120), is a protein that in humans is encoded ...

IL-17RA/RC receptor complex is composed of both alpha helices and beta sheets and its extracellular part contains two ... and second other family subunit, thus forming heteromeric receptor binding different ligands. IL-17A, a founding member of IL- ... Interleukin-17 receptor (IL-17R) is a cytokine receptor which belongs to new subfamily of receptors binding proinflammatory ... "Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor E". Immunity. 35 (4): 611-21. ...

Normally, when the interleukin binds to the trimeric receptor protein containing the alpha, beta, and gamma subunits, the ... Interleukin 7, Interleukin 9, Interleukin 15 and Interleukin 21. Signalling from these receptors normally promotes growth and ... This gene encodes the interleukin receptor common gamma chain protein, which is a cytokine receptor sub-unit that is part of ... which is a common subunit of the individual receptors for Interleukin 2, Interleukin 4, ...

Born TL, Thomassen E, Bird TA, Sims JE (1998). "Cloning of a novel receptor subunit, AcPL, required for interleukin-18 ... Sareneva T, Julkunen I, Matikainen S (2000). "IFN-alpha and IL-12 induce IL-18 receptor gene expression in human NK and T cells ... "Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling". J. Biol. Chem. 273 (45): 29445-50. doi: ... Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is a human ...

... 12 (IL-12) is a disulphide-bonded heterodimer consisting of a 35kDa alpha subunit and a 40kDa beta subunit. It is ... The receptors can both bind all three forms of IL-1 (IL-1 alpha, IL-1 beta and IL-1 receptor antagonist). The crystal ... Interleukin 1 alpha and interleukin 1 beta (IL1 alpha and IL1 beta) are cytokines that participate in the regulation of immune ... Gately MK, Renzetti LM, Magram J, Stern AS, Adorini L, Gubler U, Presky DH (1998). "The interleukin-12/interleukin-12-receptor ...

FcεRI is a tetrameric receptor complex that binds Fc portion of the ε heavy chain of IgE. It consists of one alpha (FcεRIα - ... It lacks the beta subunit on other cells. It is constitutively expressed on mast cells and basophils and is inducible in ... interleukins, leukotrienes, and prostaglandins) that promote inflammation. The most known mediator is histamine, which results ... The high-affinity IgE receptor, also known as FcεRI, or Fc epsilon RI, is the high-affinity receptor for the Fc region of ...