... , is a subunit of the interleukin-20 receptor, the interleukin-26 receptor, and the ... The interleukin 20 receptor, alpha subunit is also referred to as IL20R1 or IL20RA. The IL20RA receptor is involved in both pro ... "The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor ... IL20RA, along with the IL-20 receptor, beta subunit, form the heterodimeric interleukin-20 receptor, which binds the cytokines ...
Interleukin 11 receptor, alpha subunit is a subunit of the interleukin 11 receptor. IL11RA is its human gene. Interleukin 11 is ... "Entrez Gene: IL11RA interleukin 11 receptor, alpha". Chérel M, Sorel M, Lebeau B, et al. (1995). "Molecular cloning of two ... 2007). "Expression of interleukin-11 (IL-11) and IL-11 receptor alpha in human gastric carcinoma and IL-11 upregulates the ... 1996). "The human interleukin-11 receptor alpha gene (IL11RA): genomic organization and chromosome mapping". Genomics. 32 (1): ...
Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 ... Interleukin 5 receptor alpha subunit has been shown to interact with: Interleukin 5, Janus kinase 2, Protein unc-119 homolog, ... The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for ... Interleukin-5 receptor subunit alpha) at the PDBe-KB. This article incorporates text from the United States National Library of ...
Interleukin 27 receptor, alpha is a subunit of the interleukin-27 receptor. IL27RA is its human gene. In mice, CD4+ helper T- ... Interleukin 27 receptor, alpha subunit has been shown to interact with STAT1. ENSG00000288185 GRCh38: Ensembl release 89: ... "Entrez Gene: IL27RA interleukin 27 receptor, alpha". Takeda A, Hamano S, Yamanaka A, Hanada T, Ishibashi T, Mak TW, Yoshimura A ... This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is ...
... consisting of alpha (IL2RA), beta (IL2RB) and the common gamma chain (IL2RG). As the name indicates, this receptor interacts ... where also alpha subunit (CD25) constructs the IL-2 receptor and provides enhanced specific binding force. After activation of ... Interleukin-2 receptor alpha chain (also called TAC antigen, P55 and mainly CD25) is a protein involved in assembly of high- ... receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL-2 ...
This protein also forms one of the three subunits of the IL-15 receptor. Activation of the receptor increases proliferation of ... The intermediate affinity form consists of a gamma/beta subunit heterodimer, while the high affinity form consists of an alpha/ ... forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. ... generation of three receptor forms by cloned human alpha and beta chain cDNA's". Science. 244 (4904): 551-6. Bibcode:1989Sci... ...
1998). "Heteromerization of the gammac chain with the interleukin-9 receptor alpha subunit leads to STAT activation and ... 2000). "14-3-3zeta interacts with the alpha-chain of human interleukin 9 receptor". Biochem. J. 345 (3): 741-7. doi:10.1042/ ... 1999). "Tip60 interacts with human interleukin-9 receptor alpha-chain". Biochem. Biophys. Res. Commun. 263 (1): 149-55. doi: ... Interleukin 9 receptor (IL9R) also known as CD129 (Cluster of Differentiation 129) is a type I cytokine receptor. IL9R also ...
... is a subunit for the interleukin-10 receptor. IL10RA, is its human gene. IL10RA has also ... Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Interleukin 10 receptor, alpha subunit ... IL10RA interleukin 10 receptor, alpha". Ho AS, Liu Y, Khan TA, Hsu DH, Bazan JF, Moore KW (December 1993). "A receptor for ... Ho AS, Liu Y, Khan TA, Hsu DH, Bazan JF, Moore KW (1994). "A receptor for interleukin 10 is related to interferon receptors". ...
... is a subunit of the interleukin 15 receptor that in humans is encoded by the IL15RA gene ... The IL-15 receptor is composed of three subunits: IL-15R alpha, CD122, and CD132. Two of these subunits, CD122 and CD132, are ... "Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes". J. ... "Identification of an interleukin-15alpha receptor-binding site on human interleukin-15". J. Biol. Chem. 279 (23): 24313-22. doi ...
... binding interleukin-15. It consists of an interleukin 15 receptor, alpha subunit and shares common beta and gamma subunits with ... Interleukin-15 receptor is a type I cytokine receptor, ... Receptors,+Interleukin-15 at the U.S. National Library of ... "Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes". J. ... PDB: 2B5I​Wang X, Rickert M, Garcia KC (November 2005). "Structure of the quaternary complex of interleukin-2 with its alpha, ...
Interleukin-13 receptor subunit alpha-2 (IL-13Rα2), also known as CD213A2 (cluster of differentiation 213A2), is a membrane ... Interleukin-13 receptor subunit alpha-2) at the PDBe-KB. This article incorporates text from the United States National Library ... "Entrez Gene: IL13RA2 interleukin 13 receptor, alpha 2". Fujisawa T, Joshi B, Nakajima A, Puri RK (November 2009). "A novel role ... IL-13Rα2 is closely related to IL-13Rα1, a subunit of the interleukin-13 receptor complex. This protein binds IL13 with high ...
Interleukin-22 receptor subunit alpha-2 (IL-22RA2), also known as interleukin-22 binding protein (IL-22BP) is a naturally ... April 2009). "Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22". FEBS Letters. 583 (7): 1072-1077 ... IL-22BP belongs to the class II cytokine receptor family and it is a soluble receptor homolog of IL-22R (aliases IL-22RA1/IL- ... IL-22BP also shares homology with other related cytokine receptors IL-10RB, and IL-20RA. IL-22BP is a secreted protein that ...
Milatovich A, Kitamura T, Miyajima A, Francke U (1993). "Gene for the alpha-subunit of the human interleukin-3 receptor (IL3RA ... The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for ... "Structure of the gene encoding the alpha subunit of the human interleukin 3 receptor". Biochem. Biophys. Res. Commun. 208 (1): ... "Entrez Gene: IL3RA interleukin 3 receptor, alpha (low affinity)". Stomski FC, Sun Q, Bagley CJ, Woodcock J, Goodall G, Andrews ...
IL-5 has been shown to interact with interleukin 5 receptor alpha subunit. The IL-5 receptor is composed of an α and a βc chain ... "Binding interactions of human interleukin 5 with its receptor alpha subunit. Large scale production, structural, and functional ... The α subunit is specific for the IL-5 molecule, whereas the βc subunit also recognised by interleukin 3 (IL-3) and granulocyte ... Through binding to the interleukin-5 receptor, interleukin 5 stimulates B cell growth and increases immunoglobulin secretion- ...
"JAK2 and JAK1 constitutively associate with an interleukin-5 (IL-5) receptor alpha and betac subunit, respectively, and are ... the GM-CSF receptor family (IL-3R, IL-5R and GM-CSF-R), the gp130 receptor family (e.g., IL-6R), and the single chain receptors ... "Physical interaction between interleukin-12 receptor beta 2 subunit and Jak2 tyrosine kinase: Jak2 associates with cytoplasmic ... It is a member of the Janus kinase family and has been implicated in signaling by members of the type II cytokine receptor ...
This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves ... Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1), is a human gene. The ... "Entrez Gene: IL13RA1 interleukin 13 receptor, alpha 1". Kornau HC, Schenker LT, Kennedy MB, Seeburg PH (1995). "Domain ... Orchansky PL, Kwan R, Lee F, Schrader JW (1999). "Characterization of the cytoplasmic domain of interleukin-13 receptor-alpha ...
The interleukin 28 receptor consists of an interleukin-28R alpha chain (IL-28RA) and another receptor, the beta subunit of the ... It consists of an α chain and shares a common β subunit with the interleukin-10 receptor. Binding to the interleukin-28 ... Interleukin-28 receptor is a type II cytokine receptor found largely in epithelial cells. It binds type 3 interferons, ... While the type 1 interferon receptor is diversely distributed, the Interleukin-28 receptor expression is more restricted, ...
He studied the role played by the receptor for interleukin-2 (IL-2) on the growth, differentiation and regulation of normal and ... He demonstrated that it is bound to IL-15 R alpha on the surface of antigen presenting cells and presented in trans to T-cells ... a monoclonal antibody to the receptor for interleukin-2". Blood 1988, 72(5): 1805-1816. PMID 2846094 Bielekova B, Richert N, ... "The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T- ...
The interleukin-5 receptor is a type I cytokine receptor. It is a heterodimer of the interleukin 5 receptor alpha subunit and ... "JAK2 and JAK1 constitutively associate with an interleukin-5 (IL-5) receptor alpha and betac subunit, respectively, and are ... In fact, the β-subunit of the IL-5 receptor is also found in IL-3 and GM-CSF receptors where it is associated with IL-3Rα and ... Therefore, it is known as the common β receptor or βc. As with the IL-5Rα subunit, the β subunit's cytoplasmic domain is ...
... has been shown to interact with: EYA2, GPSM2, Interleukin 8 receptor, alpha, MDFI, RGS5, and RIC8A. GRCh38: Ensembl ... alpha i-G alpha s chimeras define the function of alpha chain domains in control of G protein activation and beta gamma subunit ... "Identification of G protein alpha-subunits in RINm5F cells and their selective interaction with galanin receptor". Diabetes. 40 ... "Distribution of the alpha-subunit of the guanine nucleotide-binding protein Gi2 and its comparison to G alpha o". Journal of ...
... interleukin-1 receptor accessory protein-like 1 protein) PI4KIIIβ (type III phosphatidylinositol 4-kinase β) IP3 receptor (this ... alpha}1-subunit co-regulate synaptic transmission and nerve-terminal growth". Journal of Cell Science. 122 (22): 4109-4121. doi ... NCS-1 is a globular protein consisting of ten alpha-helices. Four pairs of alpha-helices each form independent 12-amino-acid ... It is the Ca2+-sensing subunit of the yeast phosphatidylinositol (PtdIns)-4-OH kinase, PIK1 It binds to many proteins, some in ...
... provides an overview of all the structure information available in the PDB for Human Interleukin-4 receptor subunit alpha This ... The interleukin 4 receptor is a type I cytokine receptor. It is a heterodimer, that is, composed of two subunits. IL4R is the ... Interleukin-4 receptor has been shown to interact with SHC1. The N-terminal (extracellular) portion of interleukin-4 receptor ... forming the type II IL4 receptor). This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane ...
... encoding interleukin-10 receptor subunit beta ITGB2: encoding protein integrin beta-2 ITSN1: encoding protein intersectin-1 ... encoding interferon alpha/beta receptor 1 IFNAR2: encoding interferon alpha/beta receptor 2 IFNGR2: encoding interferon gamma ... encoding enzyme subunit ATP synthase-coupling factor 6, mitochondrial ATP5PO: encoding enzyme subunit ATP synthase subunit O, ... encoding alpha-1 chain of collagen VI COL6A2: encoding alpha-2 chain of collagen VI COL18A1: encoding alpha-1 chain of collagen ...
IL-10 has been shown to interact with Interleukin 10 receptor, alpha subunit. The receptor complex for IL-10 also requires the ... Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A (2001). "Interleukin-10 and the interleukin-10 receptor". Annual Review of ... Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A (2001-01-01). "Interleukin-10 and the interleukin-10 receptor". Annual ... IL-10 signals through a receptor complex consisting of two IL-10 receptor-1 and two IL-10 receptor-2 proteins. Consequently, ...
... these subunits are also parts of receptors for other cytokines.: 713 The β and γ chains of the IL-2R are members of the type I ... The alpha chain does not participate in signaling, but the beta chain is complexed with an enzyme called Janus kinase 1 (JAK1 ... The interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as ... The three receptor chains are expressed separately and differently on various cell types and can assemble in different ...
This receptor is a heterodimer receptor complex consisting of alpha IL-4 receptor (IL-4Rα) and alpha Interleukin-13 receptor ( ... Interleukin-13 and its associated receptors with α subunit of the IL-4 receptor (IL-4Rα) allows for the downstream activation ... Interleukin-13 receptor, the IL-13 receptor GRCm38: Ensembl release 89: ENSMUSG00000020383 - Ensembl, May 2017 "Human PubMed ... IL-13 also binds to another receptor known as IL-13Rα2. IL-13Rα2 (which is labelled as a decoy receptor) is derived from Th2 ...
... an interleukin subunit coding gene located within the same gene neighborhood in humans at Xq13.1. Fusions between these two ... CXorf65 is a moderately evolving gene in reference to fibrinogen alpha and cytochrome c. CXorf65 has been documented to co- ... It belongs to the gene family pfam 15874; a two-member family for conserved putative interleukin 2 receptor gamma chain (Il2rg ... 12 (2): 280. doi:10.3390/life12020280. PMC 8875138. PMID 35207567. Pagliarulo F, Cheng PF, Brugger L, van Dijk N, van den ...
... interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor ... Stein B, Yang MX (September 1995). "Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and ... "The aryl hydrocarbon receptor interacts with estrogen receptor alpha and orphan receptors COUP-TFI and ERRalpha1". Archives of ... Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types ...
... and the production of interleukin 8 (IL-8). Like all T cells, they express the T cell receptor-CD3 complex. The T cell receptor ... Activated T cells also produce the alpha sub-unit of the IL-2 receptor (CD25 or IL-2R), enabling a fully functional receptor ... "Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation ... CD4, a co-receptor of the TCR complex, also binds to a different section of the MHC molecule. It is estimated that ...
... interleukin 6, interleukin-12 subunit alpha, and interleukin-12 subunit beta; and mouse helper and cytotoxic T cells from ... Free Fatty acid receptor 4 (FFAR4), also termed G-protein coupled receptor 120 (GPR120), is a protein that in humans is encoded ... Free fatty acid receptor Free fatty acid receptor 1 (CS1: long volume value, Articles with short description, Short description ... "Identification of G-protein-coupled receptor 120 as a tumor-promoting receptor that induces angiogenesis and migration in human ...