*Interleukin 10

In humans, interleukin 10 is encoded by the IL10 gene. IL-10 signals through a receptor complex consisting of two IL-10 ... "Entrez Gene: IL10 interleukin 10". Braat H, Rottiers P, Hommes DW, Huyghebaert N, Remaut E, Remon JP, van Deventer SJ, Neirynck ... Interleukin 10 knockout frail mice develop cardiac and vascular dysfunction with increased age. IL-10 is linked to the myokines ... Over time a more nuanced picture of IL-10's function has emerged as treatment of tumor bearing mice has been shown to inhibit ...

*Interleukin-10 receptor

... is a type II cytokine receptor. The receptor is tetrameric, composed of 2α and 2β subunits. The α ... Receptors, Interleukin-10 at the US National Library of Medicine Medical Subject Headings (MeSH). ... "Identification and functional characterization of a second chain of the interleukin-10 receptor complex". EMBO J. 16 (19): 5894 ... Liu Y, Wei SH, Ho AS, de Waal Malefyt R, Moore KW (1994). "Expression cloning and characterization of a human IL-10 receptor". ...

*Interleukin 10 receptor, beta subunit

2004). "The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 ... Interleukin 10 receptor, beta subunit is a subunit for the interleukin-10 receptor. IL10RB is its human gene. IL10RB has also ... 2000). "Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL ... Pletnev S, Magracheva E, Wlodawer A, Zdanov A (2006). "A model of the ternary complex of interleukin-10 with its soluble ...

*Interleukin 10 receptor, alpha subunit

... is a subunit for the interleukin-10 receptor. IL10RA, is its human gene. IL10RA has also ... Interleukin 10 receptor, alpha subunit has been shown to interact with: Interleukin 10 and Janus kinase 1. GRCh38: Ensembl ... Ho AS, Liu Y, Khan TA, Hsu DH, Bazan JF, Moore KW (1994). "A receptor for interleukin 10 is related to interferon receptors". ... Zdanov A, Schalk-Hihi C, Wlodawer A (1997). "Crystal structure of human interleukin-10 at 1.6 A resolution and a model of a ...

*Resolvin

Interleukin 1β, Interleukin 6, Interleukin 8, Interleukin 12, et.) and chemokines (e.g. CXCL2, CXCL8, CCL5, etc.) while ... Interleukin 8, Interleukin 2, and Granulocyte macrophage colony-stimulating factor) that orchestrate the ensuing innate ... Interleukin 10); g) inhibit activation and function of dendritic cells, activation (e.g. aggregation) of platelets, and ... Dalli, Jesmond; Serhan, Charles N. (2012-10-11). "Specific lipid mediator signatures of human phagocytes: microparticles ...

*Michel Goldman

Marchant, A.; Devière, J; Byl, B; De Groot, D; Vincent, JL; Goldman, M. (1994). "Interleukin-10 production during septicaemia ... Goriely, S; Neurath, MF; Goldman, M (2008). "How microorganisms tip the balance between interleukin-12 family members". Nature ...

*Virokine

Epstein-Barr virus encodes an interleukin protein with high sequence identity to the human interleukin-10, suggesting a recent ... Fickenscher, H; Hör, S; Küpers, H; Knappe, A; Wittmann, S; Sticht, H (February 2002). "The interleukin-10 family of cytokines ...

*Mesangial proliferative glomerulonephritis

There is some evidence that interleukin-10 may inhibit it in an animal model. It is classified as type II lupus nephritis by ... "Interleukin-10 inhibits experimental mesangial proliferative glomerulonephritis". Clin. Exp. Immunol. 128 (1): 36-43. doi: ...

*Interleukin 22

Interleukin-22 (IL-22) is protein that in humans is encoded by the IL22 gene. IL-22 is an α-helical cytokine. IL-22 binds to a ... Xie MH, Aggarwal S, Ho WH, Foster J, Zhang Z, Stinson J, Wood WI, Goddard AD, Gurney AL (Oct 2000). "Interleukin (IL)-22, a ... Weger W, Hofer A, Wolf P, El-Shabrawi Y, Renner W, Kerl H, Salmhofer W (Sep 2009). "Common polymorphisms in the interleukin-22 ... Hill T, Krougly O, Nikoopour E, Bellemore S, Lee-Chan E, Fouser LA, Hill DJ, Singh B (2013). "The involvement of interleukin-22 ...

*Subdural hematoma

Interleukin 6, Interleukin 8; while the anti-inflammatory mediator is Interleukin 10. Mediators that promote angiogenesis are: ... Examples of pro-inflammatory mediators acted in the haematoma expansion process are: Interleukin 1α (IL1A), ... 49 (1): 3-10. Retrieved 26 November 2017. . The possibility of direct effect of some vasoactive substances released by the ...

*Regulatory B cells

Asseman, C; Mauze, S; Leach, MW; Coffman, RL; Powrie, F (Oct 4, 1999). "An essential role for interleukin 10 in the function of ... Mauri, C; Gray, D; Mushtaq, N; Londei, M (Feb 17, 2003). "Prevention of arthritis by interleukin 10-producing B cells". The ... The main mechanism is a production of anti-inflammatory cytokine interleukin 10 (IL-10). The regulatory effects of Bregs were ... induction by interleukin 4 (IL-4) and IL-10". Infection and Immunity. 70 (2): 812-9. doi:10.1128/iai.70.2.812-819.2002. PMC ...

*NKG2D

Among ten known human RAET1/ULBP genes, six encode functional proteins: RAET1E/ULBP4, RAET1G/ULBP5, RAET1H/ULBP2, RAET1/ULBP1, ... "Interleukin 10 decreases MICA expression on melanoma cell surface". Immunology and Cell Biology. 89 (3): 447-57. doi:10.1038/ ... 3 (10): 781-90. doi:10.1038/nri1199. PMID 14523385. Li P, Morris DL, Willcox BE, Steinle A, Spies T, Strong RK (May 2001). " ...

*Regulatory T cell

A related suggestion with regard to interleukin 2 is that activated regulatory T cells take up interleukin 2 so avidly that ... These include Transforming growth factor beta, Interleukin 35, and Interleukin 10. It also appears that regulatory T cells can ... these T cells inhibit interferon-gamma secretion and proliferation and increase interleukin-6 and interleukin-10 secretion. A ... Annacker, O; Asseman, C; Read, S; Powrie, F (June 2003). "Interleukin-10 in the regulation of T cell-induced colitis". Journal ...

*MicroRNA 106a

"Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106a". Proc. Natl. Acad. Sci. U.S.A. 106 (14): 5761-6. ... 89 (10): 1037-50. doi:10.1007/s00109-011-0775-x. PMID 21656380. Wang Z, Liu M, Zhu H, Zhang W, He S, Hu C, Quan L, Bai J, Xu N ...

*KLF4

Liu J, Zhang H, Liu Y, Wang K, Feng Y, Liu M, Xiao X (October 2007). "KLF4 regulates the expression of interleukin-10 in ... 10 (1): 100-25. PMID 16563224. Ohnishi S, Ohnami S, Laub F, Aoki K, Suzuki K, Kanai Y, Haga K, Asaka M, Ramirez F, Yoshida T ( ... 10: 99. doi:10.1186/1476-4598-10-99. PMID 21851624. Wu A, Luo W, Zhang Q, Yang Z, Zhang G, Li S, Yao K (April 2013). "Aldehyde ... 10 (8): 1312-21. doi:10.4161/cc.10.8.15363. PMID 21490434. Sureban SM, May R, Qu D, Weygant N, Chandrakesan P, Ali N, Lightfoot ...

*IL1A

"A physical map of the region encompassing the human interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor ... Interleukin 1 alpha (IL-1α) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded ... It binds to the interleukin-1 receptor. It is on the pathway that activates tumor necrosis factor-alpha. Interleukin 1 was ... It was not until 1985 that interleukin 1 was discovered to consist of two distinct proteins, now called interleukin-1 alpha and ...

*Mouse model of colorectal and intestinal cancer

Interleukin 10 knock out mice develop invasive adenocarcinoma in the colon. Mutant mice for interleukin 2 and beta ... 1996). "Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and ... After 8-10 months, 45% to 56% of the mice developed colonic adenocarcinomas, and no mice had cancers of the small intestine. On ... 10 (12): 1433-42. doi:10.1101/gad.10.12.1433. PMID 8666228. Edelmann W, Yang K, Umar A, et al. (1997). "Mutation in the ...

*Interleukin 27

... (IL-27) is a member of the IL-12 cytokine family. It is a heterodimeric cytokine that is composed of two ... Iwasaki, Yukiko; Fujio, Keishi; Okamura, Tomohisa; Yamamoto, Kazuhiko (2015-01-27). "Interleukin-27 in T Cell Immunity". ... Iyer, Shankar Subramanian; Cheng, Genhong (2012-01-01). "Role of Interleukin 10 Transcriptional Regulation in Inflammation and ... "The biology of interleukin-27 reveals unique pro- and anti-inflammatory functions in immunity". Cytokine & Growth Factor ...

*Tumor microenvironment

... such as interleukin 4 (IL-4) and interleukin 13 (IL-13). TAMs gather in necrotic regions of tumors where they are associated ... Among such strategies are antibodies to the interleukin-10 receptor (IL10R). In a mammary carcinoma mouse model it neutralized ... 10 (1): 120-127. doi:10.1016/S0959-437X(99)00043-X. Sinkus, R.; Lorenzen, J.; Schrader, D.; Lorenzen, M.; Dargatz, M.; Holz, D ... 242 (1): 1-10. doi:10.1016/j.canlet.2005.12.005. PMID 16413116. Retrieved June 2015. Check date values in: ,access-date= (help ...

*Infectious tolerance

"Interleukin-10-secreting type 1 regulatory T cells in rodents and humans". Immunological Reviews. 212: 28-50. doi:10.1111/j. ... High IL-10 production is characteristic for Tr1 cells themselves and they also produce TGF-β. In the presence of IL-10 can be ... Tr1 cells are dependent on IL-10 and TGF-β as well as Tregs, but differ from them by lacking expression of Foxp3. ... 10 (5): 518-524. ISSN 0952-7915. PMID 9794831. Kendal, Adrian R.; Waldmann, Herman (October 2010). "Infectious tolerance: ...

*Interleukin 28 receptor, alpha subunit

... including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines ... Interleukin 28 receptor, alpha subunit is a subunit for the interleukin-28 receptor. IL28RA is its human gene. The protein ... This protein forms a receptor complex with interleukin 10 receptor, beta (IL10RB). The receptor complex has been shown to ... IL28RA interleukin 28 receptor, alpha (interferon, lambda receptor)". ...

*Promoter (genetics)

Hobbs, K.; Negri, J.; Klinnert, M.; Rosenwasser, L. J.; Borish, L. (1998). "Interleukin-10 and Transforming Growth Factor- β ... "Nuclear factor-kappaB-dependent induction of interleukin-8 gene expression by tumor necrosis factor alpha: evidence for an ... The sequence at -10 (the -10 element) has the consensus sequence TATAAT. The sequence at -35 (the -35 element) has the ... 25 (10): 1010-22. doi:10.1101/gad.2037511. PMC 3093116 . PMID 21576262. Chen HY, Shao CJ, Chen FR, Kwan AL, Chen ZP (2010). " ...

*Lactococcus lactis

"A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's disease". Clin Gastroenterol Hepatol. 4 (6): 754- ... 15 (10): 498-505. doi:10.1016/j.tifs.2004.03.003. CS1 maint: Multiple names: authors list (link) Aguirre M, Collins MD (August ... Zhang, Bo; Li, Angdi; Zuo, Fanglei; Yu, Rui; Zeng, Zhu; Ma, Huiqin; Chen, Shangwu (2016-06-10). "Recombinant Lactococcus lactis ...

*Genetically modified bacterium

"A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's disease". Clinical Gastroenterology and ... doi:10.1160/TH07-10-0593. PMID 18449413. Bryant J, Baxter L, Cave CB, Milne R (July 2007). "Recombinant growth hormone for ... Valda D, Dowling J (10 December 2010). "Making Microbes Better Miners". Business Chile Magazine. Retrieved 21 March 2012. Ruiz ...

*Post-transplant lymphoproliferative disorder

Production of an interleukin-10, an endogenous, pro-regulatory cytokine, has also been implicated. In immunocompetent patients ...

*Childbirth

"Fetal distress increases interleukin-6 and interleukin-8 and decreases tumour necrosis factor-alpha cord blood levels in ... The first stage begins with crampy abdominal or back pains that last around half a minute and occur every ten to thirty minutes ... three to four contractions every ten minutes rupture of membranes cervical dilation of 3 to 4 cm Health care providers may ... Full dilation is reached when the cervix has widened enough to allow passage of the baby's head, around 10 cm dilation for a ...