Interferon alpha-n3
... (Alferon-N) is a medication consisting of purified natural human interferon alpha proteins used for the ...
Interferon alpha-1
"Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha ... Interferon alpha-1 is a protein that in humans is encoded by the IFNA1 gene. Leukocyte interferon is produced predominantly by ... "Entrez Gene: IFNA1 interferon, alpha 1". Lengyel P (1982). "Biochemistry of interferons and their actions". Annual Review of ... The type I IFNs bind to the interferon alpha receptor (IFNAR), which consists of two subunits, IFNAR1 (α-subunit) and IFNAR2 (β ...
Interferon alfa-2b
... is an antiviral or antineoplastic drug. It is a recombinant form of the protein Interferon alpha-2 that was ... "Therapeutic Effectiveness of Interferon Alpha 2b Treatment for COVID-19 Patient Recovery". Journal of Interferon & Cytokine ... Forney B. "Interferon Alpha-2B for Veterinary Use". Wedgewood Pharmacy. Archived from the original on 2021-10-19. Yang LM, Xue ... The study demonstrated around 10,000 fold reduction in the quantity of virus that was pre-treated with Interferon alpha 48 ...
Interferon
PEGylated interferon-alpha-2b (Pegintron), polyethylene glycol is linked to the interferon molecule to make the interferon last ... Interferons can disrupt signaling by other stimuli. For example, interferon alpha induces RIG-G, which disrupts the CSN5- ... The analyses showed the reality of interferon activity by chemical verification. The purification of human alpha interferon was ... clinical trials and the preparation of small amounts of interferon messenger RNA to clone the human alpha and beta interferon ...
Interferon type I
Wang YX, Xu WG, Sun XJ, Chen YZ, Liu XY, Tang H, Jiang CL (November 2004). "Fever of recombinant human interferon-alpha is ... The recombinant type is interferon alfacon-1. The pegylated types are pegylated interferon alfa-2a and pegylated interferon ... Major depression during interferon-alpha treatment: vulnerability and prevention. Dialogues Clin Neurosci. 2009;11(4):417-425. ... Interferons bind to interferon receptors. All type I IFNs bind to a specific cell surface receptor complex known as the IFN-α ...
Recombinant feline interferon omega
The protein is around 60% identical to human alpha interferons, but the Ueda team deemed it an "omega-type" interferon due to ... Phylogenic analysis in 2007 puts it as an alpha-type interferon. As the approved regimen is very costly, RFeIFN-ω has been ... It is a immunostimulant in the interferon family. The feline interferon "omega" gene was first cloned in 1992. It was first ... is a recombinant version of a cat interferon alpha. It is used to treat a range of viral diseases in cats and dogs, including ...
Superantigen
October 2001). "Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity". Immunity. 15 ( ... The activated macrophages, in turn, over-produce proinflammatory cytokines such as IL-1, IL-6 and TNF-alpha. TNF-alpha is ... Superantigens bind first to the MHC class II and then coordinate to the variable alpha- or beta chain of T-cell Receptors (TCR ... Some of the major products are IL-1, IL-2, IL-6, TNF-α, gamma interferon (IFN-γ), macrophage inflammatory protein 1α (MIP-1α), ...
Differential diagnoses of depression
Interferons; proteins produced by the human body, three types have been identified alpha, beta and gamma. Synthetic versions ... Debien C, De Chouly De Lenclave MB, Foutrein P, Bailly D (2001). "Alpha-interferon and mental disorders". L'Encéphale. 27 (4): ... are utilized in various medications used to treat different medical conditions such as the use of interferon-alpha in cancer ... All three classes of interferons may cause depression and suicidal ideation. The neuropsychiatric effects of chronic ...
Interferon Lambda 3
October 2009). "Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic ... Interferon lambda genes encode cytokines classified as type III interferons, which are distantly related to type I interferons ... October 2009). "IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy". Nature ... Lu YF, Goldstein DB, Urban TJ, Bradrick SS (February 2015). "Interferon-λ4 is a cell-autonomous type III interferon associated ...
Interferon Lambda 4
October 2009). "Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic ... October 2009). "IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy". Nature ... July 2015). "Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control ... January 2014). "Polymorphisms of interferon-λ4 and IL28B - effects on treatment response to interferon/ribavirin in patients ...
IFNA21
Hussain M, Gill DS, Liao MJ (1997). "Identification of interferon-alpha 7, -alpha 14, and -alpha 21 variants in the genome of a ... 1985). "Novel human leukocyte interferon subtype and structural comparison of alpha interferon genes". J. Interferon Res. 4 (4 ... 1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest". Mol. Cell. Biol. ... Interferon alpha-21 is a protein that in humans is encoded by the IFNA21 gene. GRCh38: Ensembl release 89: ENSG00000137080 - ...
IFNA4
1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest". Mol. Cell. Biol. ... Interferon alpha-4 is a protein that in humans is encoded by the IFNA4 gene. GRCh38: Ensembl release 89: ENSG00000236637 - ... "Entrez Gene: IFNA4 interferon, alpha 4". Mizoguchi J, Pitha PM, Raj NB (1985). "Efficient expression in Escherichia coli of two ... 1984). "Nucleotide sequence and expression in E. coli of a human interferon-alpha gene selected from a genomic library using ...
IFNA8
"Interferon-alpha 8b is the only variant of interferon-alpha 8 identified in a large human population". J. Interferon Cytokine ... alpha 8". Henco K, Brosius J, Fujisawa A, et al. (1985). "Structural relationship of human interferon alpha genes and ... 1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest". Mol. Cell. Biol. ... Interferon alpha-8 is a protein that in humans is encoded by the IFNA8 gene. GRCh38: Ensembl release 89: ENSG00000120242 - ...
IFNA7
Hussain M, Gill DS, Liao MJ (1997). "Identification of interferon-alpha 7, -alpha 14, and -alpha 21 variants in the genome of a ... "Entrez Gene: IFNA7 interferon, alpha 7". Conti L, Fantuzzi L, Del Cornò M, et al. (2005). "Immunomodulatory effects of the HIV- ... 1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest". Mol. Cell. Biol. ... Interferon alpha-7 is a protein that in humans is encoded by the IFNA7 gene. GRCh38: Ensembl release 89: ENSG00000214042 - ...
IFNA5
... alpha 5". Henco K, Brosius J, Fujisawa A, et al. (1985). "Structural relationship of human interferon alpha genes and ... 1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest". Mol. Cell. Biol. ... Interferon alpha-5 is a protein that in humans is encoded by the IFNA5 gene. GRCh38: Ensembl release 89: ENSG00000147873 - ... 1999). "Determination of residues involved in ligand binding and signal transmission in the human IFN-alpha receptor 2". J. ...
IFNA14
Hussain M, Gill DS, Liao MJ (1997). "Identification of interferon-alpha 7, -alpha 14, and -alpha 21 variants in the genome of a ... "Entrez Gene: IFNA14 interferon, alpha 14". Sen GC, Lengyel P (1992). "The interferon system. A bird's eye view of its ... 1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest". Mol. Cell. Biol. ... Interferon alpha-14 is a protein that in humans is encoded by the IFNA14 gene. GRCh38: Ensembl release 89: ENSG00000228083 - ...
IFNA17
"Entrez Gene: IFNA17 interferon, alpha 17". Sen GC, Lengyel P (1992). "The interferon system. A bird's eye view of its ... 1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest". Mol. Cell. Biol. ... Interferon alpha-17 is a protein that in humans is encoded by the IFNA17 gene. GRCh38: Ensembl release 89: ENSG00000234829 - ... 2003). "Interferon, alpha 17 (IFNA17) Ile184Arg polymorphism and cervical cancer risk". Cancer Lett. 189 (2): 183-8. doi: ...
Feline infectious peritonitis
"Interferon Alpha-2B for Veterinary Use". Wedgewood Pharmacy. Legendre, A. M.; Bartges, J. W. (1 August 2009). "Effect of ... The most common drugs of this class for treating FIP are either recombinant feline interferon omega (Virbagen Omega, Virbac) or ... the feline version feline interferon is more effective. An experimental polyprenyl immunostimulant (PI) is manufactured by Sass ... human interferon alfa-2b. Since the human version ends up being targeted by the immune system for being a foreign antigen, ...
IFNA10
... alpha 10". Bartholomew C, Windass JD (1989). "Identification of a functional allele of a human interferon-alpha gene previously ... 1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest". Mol. Cell. Biol. ... Interferon alpha-10 is a protein that in humans is encoded by the IFNA10 gene. GRCh38: Ensembl release 89: ENSG00000186803 - ... Nyman TA, Tölö H, Parkkinen J, Kalkkinen N (1998). "Identification of nine interferon-alpha subtypes produced by Sendai virus- ...
IFNA2
Interferon alpha-2 is a protein that in humans is encoded by the IFNA2 gene. Human interferon alpha-2 (IFNα2) is a cytokine ... "Entrez Gene: IFNA2 interferon, alpha 2". Gresser I (2015). "On intuition and the discovery of interferon". Cytokine Growth ... There are 3 types of IFNs: Interferon type I, Interferon type II and Interferon type III. The type II IFN, also called IFNγ, is ... Sleijfer S, Bannink M, Van Gool AR, Kruit WH, Stoter G (December 2005). "Side effects of interferon-alpha therapy". Pharm World ...
IFNA6
1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest". Mol. Cell. Biol. ... Interferon alpha-6 is a protein that in humans is encoded by the IFNA6 gene. GRCh38: Ensembl release 89: ENSG00000120235 - ... "Entrez Gene: IFNA6 interferon, alpha 6". Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion ... Nyman TA, Tölö H, Parkkinen J, Kalkkinen N (1998). "Identification of nine interferon-alpha subtypes produced by Sendai virus- ...
Charles Raison
During Interferon-alpha Administration (2012). "Association with Fatigue and CSF Dopamine Concentrations". Brain, Behavior, and ... Alpha Omega Alpha, Washington University chapter 1991: Missouri State Medical Association Award 1984: Colorado State Fellow, ... Raison, C.L., Afdhal, N.H. Neuropsychiatric side effects associated with interferon-alfa plus ribavirin therapy: Treatment and ... Raison, C.L., Afdhal, N.H. Neuropsychiatric side effects associated with interferon-alfa plus ribavirin therapy: Recognition ...
Depression and immune function
December 2007). "Effects of interferon-alpha on rhesus monkeys: a nonhuman primate model of cytokine-induced depression". ... Capuron L, Miller AH (December 2004). "Cytokines and psychopathology: lessons from interferon-alpha". Biological Psychiatry. 56 ... March 2001). "Paroxetine for the prevention of depression induced by high-dose interferon alfa". The New England Journal of ... One important inflammatory cytokine, interferon-α (IFN- α), is correlated with the development of depressive symptoms through ...
Kynurenine
Capuron L, Neurauter G, Musselman DL, Lawson DH, Nemeroff CB, Fuchs D, Miller AH (2003). "Interferon-alpha-induced changes in ... Evidence suggests that increased kynurenine production may precipitate depressive symptoms associated with interferon treatment ... Alpha-Amino acids, Human metabolites, NMDA receptor antagonists). ...
Interferon tau
Similar to other Type I interferons, IFN-τ binds to the Interferon-alpha/beta receptor (IFNAR). Its molecular weight is between ... Interferon tau (IFNτ, IFNT) is a Type I interferon made of a single chain of amino acids. IFN-τ was first discovered in ... October 2001). "Interferon regulatory factor-two restricts expression of interferon-stimulated genes to the endometrial stroma ... Roberts RM (October 2007). "Interferon-tau, a Type 1 interferon involved in maternal recognition of pregnancy". Cytokine & ...
IFI27
"Entrez Gene: IFI27 interferon, alpha-inducible protein 27". Taulés M, Rius E, Talaya D, López-Girona A, Bachs O, Agell N ( ... Interferon alpha-inducible protein 27 is a protein that in humans is encoded by the IFI27 gene. ENSG00000275214 GRCh38: Ensembl ... November 2001). "The interferon alpha induced protein ISG12 is localized to the nuclear membrane". European Journal of ... September 1993). "Identification of a new interferon-alpha-inducible gene (p27) on human chromosome 14q32 and its expression in ...
Diffuse neonatal hemangiomatosis
The use of Interferon Alpha-2a in infants that are resistant to corticosteroid treatment is an ongoing study of effectiveness ... Interferon Alpha-2a is an anti-viral medication. It was studied among 20 neonatal and infant subjects that had life-threatening ... and three infants received additional treatment with alpha-interferon after poor response to the steroids. The review concluded ... They were given daily subcutaneous injections of Interferon Alfa-2a 3 million units/0.5mL. The duration of treatment varied ...
IFI6
Interferon alpha-inducible protein 6 is a protein that in humans is encoded by the IFI6 gene. This gene was first identified as ... "Entrez Gene: IFI6 interferon, alpha-inducible protein 6". Richardson RB, Ohlson MB, Eitson JL, Kumar A, McDougal MB, Boys IN, ... "Characterization of a human gene inducible by alpha- and beta-interferons and its expression in mouse cells". The EMBO Journal ... Porter AC, Chernajovsky Y, Dale TC, Gilbert CS, Stark GR, Kerr IM (January 1988). "Interferon response element of the human ...
Levilactobacillus brevis
coagulans on interferon-alpha producing capacity in humans". J Am Coll Nutr. 15 (4): 408-12. doi:10.1080/07315724.1996.10718617 ...
Peginterferon alfa-2a
Pegylated interferon alfa-2a is in the alpha interferon family of medications. It is pegylated to protect the molecule from ... Wikimedia Commons has media related to Interferon-alpha 2a. "Peginterferon alfa-2a". Drug Information Portal. U.S. National ... Interferons are proteins released in the body in response to viral infections. Interferons are important for fighting viruses ... For genotype 1 hepatitis C treated with pegylated interferon alfa-2a or pegylated interferon alfa-2b combined with ribavirin, ...