The human variant of BSP is called bone sialoprotein 2 also known as cell-binding sialoprotein or integrin-binding sialoprotein ... Oldberg A, Franzén A, Heinegård D (December 1988). "The primary structure of a cell-binding bone sialoprotein". J. Biol. Chem. ... Tye CE, Hunter GK, Goldberg HA (April 2005). "Identification of the type I collagen-binding domain of bone sialoprotein and ... and a classical integrin-binding motif (RGD) near the C-terminal (rattus norvegicus residues 288-291). BSP has been ...
The family of non-collagenous proteins known as SIBLING proteins, standing for small integrin-binding ligand, N-linked ... The following are categorized as SIBLING proteins: osteopontin (OPN) bone sialoprotein (BSP) dentin matrix protein 1 (DMP1) ...
OPN binds to several integrin receptors including α4β1, α9β1, and α9β4 expressed by leukocytes. These receptors have been well- ... Oldberg A, Jirskog-Hed B, Axelsson S, Heinegård D (December 1989). "Regulation of bone sialoprotein mRNA by steroid hormones". ... OPN contains and RGD integrin-binding motif Activated T cells are promoted by IL-12 to differentiate towards the Th1 type, ... Although the exact mechanisms of osteopontin signaling in PDAC are unknown, it binds to CD44 and integrins to trigger processes ...
HN protein binding to NKp46 and/or NKp44 results in the lysis of cells whose surfaces display the HN protein or its fragments. ... Bresalier RS, Rockwell RW, Dahiya R, Duh QY, Kim YS (February 1990). "Cell surface sialoprotein alterations in metastatic ... integrin)). Mac-1 and LFA-1 are receptors found on leukocytes. This induced production happens through the activation of ... Binding to a host cell membrane of viral proteins (M, HN and F) promotes their interaction with RNP complex, which is composed ...