The insulin-like growth factor-binding protein (IGFBP) serves as a transport protein for insulin-like growth factor 1 (IGF-1). ... "Role of insulin-like growth factor binding proteins in the control of IGF actions". Prog. Growth Factor Res. 6 (2-4): 357-66. ... November 1998). "Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): ... ISBN 81-7895-002-2. Insulin-like+growth+factor+binding+proteins at the U.S. National Library of Medicine Medical Subject ...

"Transferrin binds insulin-like growth factors and affects binding properties of insulin-like growth factor binding protein-3". ... "Factors regulating insulin-like growth factor-binding protein-3 binding, processing, and potentiation of insulin-like growth ... "Interaction of insulin-like growth factor binding protein-3 with latent transforming growth factor-beta binding protein-1". ... of insulin-like growth factor binding proteins and of the acid-labile subunit of the insulin-like growth factor ternary binding ...

1999). "Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF ... Insulin-like growth factor-binding protein 5 (IBF-5) is a protein that in humans is encoded by the IGFBP5 gene. An IGFBP5 gene ... Kiefer MC, Ioh RS, Bauer DM, Zapf J (1991). "Molecular cloning of a new human insulin-like growth factor binding protein". ... 1998). "Insulin-like growth factor-binding protein-5 is cleaved by physiological concentrations of thrombin". Endocrinology. ...

"Transferrin binds insulin-like growth factors and affects binding properties of insulin-like growth factor binding protein-3". ... It is believed to be a major fetal growth factor in contrast to insulin-like growth factor 1 (IGF-1), which is a major growth ... Insulin-like growth factor 2 has been shown to interact with IGFBP3 and transferrin. Insulin-like growth factor 2 receptor ... "Structural determinants of ligand and cell surface binding of insulin-like growth factor-binding protein-3". The Journal of ...

"Total and free insulin-like growth factor I, insulin-like growth factor binding protein 3 and acid-labile subunit reflect ... IGFALS insulin-like growth factor binding protein, acid labile subunit". Twigg SM, Baxter RC (March 1998). "Insulin-like growth ... Insulin-like growth factor binding protein, acid labile subunit, also known as IGFALS, is a protein which in humans is encoded ... The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and ...

ADAM 12, a metalloprotease that binds insulin growth factor binding protein-3 (IGFBP-3), appears to be an effective early Down ... interacts with insulin-like growth factor-binding protein-3". J. Biol. Chem. 275 (24): 18574-80. doi:10.1074/jbc.M002172200. ... interacts with insulin-like growth factor-binding protein-3". J. Biol. Chem. 275 (24): 18574-80. doi:10.1074/jbc.M002172200. ... binds ADAM12/meltrin alpha and up-regulates ectodomain shedding of heparin-binding epidermal growth factor-like growth factor ...

"Testosterone increases insulin-like growth factor-1 and insulin-like growth factor-binding protein". Annals of Clinical and ... Dihydrotestosterone also plays an important role in male sexual function and may also be a contributing factor of ischemic ... Side effects of testosterone enanthate include symptoms of masculinization like acne, increased hair growth, voice changes, and ... These masculine characteristics include: clitoral hypertrophy, androgenic alopecia, growth of body hair and deepening of the ...

"Bioactive insulin-like growth factor (IGF) I and IGF-binding protein-1 in anorexia nervosa". The Journal of Clinical ... A risk factor for anorexia is trauma. Although the prevalence rates vary greatly, between 37% and 100%, there appears to be a ... Typically, growth hormone (GH) levels are high, but levels of IGF-1, the downstream hormone that should be released in response ... Cultural factors also appear to play a role, with societies that value thinness having higher rates of the disease. ...

2007). "N-Acetylgalactosaminyltransferase 14, a novel insulin-like growth factor binding protein-3 binding partner". Biochem. ... 2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and ... GALNT enzymes catalyze the first step in the O-glycosylation of mammalian proteins by transferring N-acetyl-D-galactosamine ( ... 8 (5): 2215-2220. doi:10.3892/ol.2014.2507. PMC 4186602. PMID 25295111. Lin WR, Hsu CW, Chen YC, Chang ML, Liang KH, Huang YH, ...

... a novel insulin-like growth factor-binding protein-5 proteinase". J Biol Chem. 276 (24): 21849-53. doi:10.1074/jbc.M102191200. ... "Cellular actions of the insulin-like growth factor binding proteins". Endocr. Rev. 23 (6): 824-54. doi:10.1210/er.2001-0033. ... "Isolation and characterization of circulating 13-kDa C-terminal fragments of human insulin-like growth factor binding protein-5 ... Pappalysin-2 also known as pregnancy-associated plasma protein A2 (PAPP-A2) is a protein that in humans is encoded by the ...

"Transferrin binds insulin-like growth factors and affects binding properties of insulin-like growth factor binding protein-3". ... "Transferrin is an insulin-like growth factor-binding protein-3 binding protein". The Journal of Clinical Endocrinology and ... Transferrin has been shown to interact with insulin-like growth factor 2 and IGFBP3. Transcriptional regulation of transferrin ... Some invertebrates have proteins that act like transferrin found in the hemolymph. When not bound to iron, transferrin is known ...

Insulin-like growth factor-binding protein 2 is a protein that in humans is encoded by the IGFBP2 gene. GRCh38: Ensembl release ... Bach LA, Rechler MM (1996). "Measurement of insulin-like growth factor (IGF)-II binding to purified IGF binding proteins 1-6: ... 1991). "Two insulin-like growth factor (IGF)-binding proteins are responsible for the selective affinity for IGF-II of ... Chesik D, De Keyser J, Wilczak N (2007). "Insulin-like growth factor binding protein-2 as a regulator of IGF actions in CNS: ...

Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains". J. Biol. Chem. 272 (5): 2659 ... Welch PJ, Wang JY (November 1993). "A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl ... an eps8 binding protein that regulates cell growth". Oncogene. 14 (2): 233-41. doi:10.1038/sj.onc.1200822. PMID 9010225. ... Ren R, Ye ZS, Baltimore D (April 1994). "Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding ...

Growth factor receptor-bound protein 10 also known as insulin receptor-binding protein Grb-IR is a protein that in humans is ... This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor ... Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains". J Biol Chem. 272 (5): 2659- ... Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains". J. Biol. Chem. 272 (5): 2659 ...

IGF2R is a multifunctional protein receptor that binds insulin-like growth factor 2 (IGF2) at the cell surface and mannose-6- ... Insulin-like growth factor 2 receptor has been shown to interact with M6PRBP1. The insulin-like growth factor 2 receptor ... Ilvesmäki V, Blum WF, Voutilainen R (1994). "Insulin-like growth factor binding proteins in the human adrenal gland". Mol. Cell ... Zhou J, Bondy C (1992). "Insulin-like growth factor-II and its binding proteins in placental development". Endocrinology. 131 ( ...

"Expression of growth hormone-releasing factor, growth hormone, insulin-like growth factor-1 and its binding proteins in human ... Insulin-like growth factor-binding protein 7 is a protein that in humans is encoded by the IGFBP7 gene. The major function of ... Wilson HM, Birnbaum RS, Poot M, Quinn LS, Swisshelm K (2002). "Insulin-like growth factor binding protein-related protein 1 ... dynamics and heparin binding of the C-terminal domain of insulin-like growth factor-binding protein-2 (IGFBP-2)". J. Mol. Biol ...

Placental alpha microglobulin-1 (PAMG-1) IGFBP1 (Insulin-like growth factor binding protein-1) Norwitz, Errol R.; Arulkumaran, ... In cases of PPROM, proteins that bind and cross-link collagen to increase its tensile strength are altered. Breakdown of ... Risk factors include infection of the amniotic fluid, prior PROM, bleeding in the later parts of pregnancy, smoking, and a ... The cause of PROM is not clearly understood, but the following are risk factors that increase the chance of it occurring. In ...

Gui Y, Murphy LJ (May 2001). "Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) binds to fibronectin (FN): ... "Co-localization of insulin-like growth factor binding protein 3 and fibronectin in human articular cartilage". Osteoarthritis ... collagen-binding (I6-9), fibulin-1-binding (III13-14), heparin-binding and syndecan-binding (III12-14). Fibronectin has ... Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans (e.g ...

"Binding of mutants of human insulin-like growth factor II to insulin-like growth factor binding proteins 1-6". J. Biol. Chem. ... Insulin-like growth factor-binding protein 4 is a protein that in humans is encoded by the IGFBP4 gene. This gene is a member ... "Purification of a colon cancer cell growth inhibitor and its identification as an insulin-like growth factor binding protein". ... The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non- ...

2003). "ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts". ... The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, ... and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Two ... ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor ...

... insulin-like growth factor binding protein 1". Rajaram S, Baylink DJ, Mohan S (1998). "Insulin-like growth factor- ... Insulin-like growth factor-binding protein 1 (IBP-1) also known as placental protein 12 (PP12) is a protein that in humans is ... The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein ... 1993). "Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by ...

... identification of transglutaminase 2 as an insulin-like growth factor-binding protein-3 kinase". The Journal of Biological ... In the extracellular space, tTG binds to proteins of the extracellular matrix (ECM), binding particularly tightly to ... Endoplasmic reticulum (ER)-resident protein 57 (ERp57), a protein in the ER that promotes folding of nascent proteins and is ... Multiple Ca2+ can bind to a single tTG molecule. Specifically, tTG binds up to 6 calcium ions at 5 different binding sites. ...

1993). "Binding of mutants of human insulin-like growth factor II to insulin-like growth factor binding proteins 1-6". J. Biol ... 1999). "Insulin-like growth factors (IGF-I, free IGF-I and IGF-II) and insulin-like growth factor binding proteins (IGFBP-2, ... "Entrez Gene: IGFBP6 insulin-like growth factor binding protein 6". Wood AW, Duan C, Bern HA (2005). "Insulin-like growth factor ... 2001). "Transferrin is an insulin-like growth factor-binding protein-3 binding protein". J. Clin. Endocrinol. Metab. 86 (4): ...

Insulin-like growth factor 2 mRNA-binding protein 1 is a protein that in humans is encoded by the IGF2BP1 gene. This gene ... 2000). "H19 RNA binds four molecules of insulin-like growth factor II mRNA-binding protein". J. Biol. Chem. 275 (38): 29562-9. ... "Entrez Gene: IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1". Perycz M, Urbanska AS, Krawczyk P, Parobczak K, ... 2005). "Targeted knockdown of the RNA-binding protein CRD-BP promotes cell proliferation via an insulin-like growth factor II- ...

Insulin-like growth factor 2 mRNA-binding protein 3 is a protein that in humans is encoded by the IGF2BP3 gene. The protein ... "Entrez Gene: IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3". Yaniv K, Yisraeli JK (2002). "The involvement of a ... UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late ... "The RNA-binding protein IMP-3 is a translational activator of insulin-like growth factor II leader-3 mRNA during proliferation ...

Insulin-like growth factor 2 mRNA-binding protein 2 is a protein that in humans is encoded by the IGF2BP2 gene. This gene ... "Entrez Gene: IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2". Yisraeli JK (2005). "VICKZ proteins: a multi- ... "Differential regulation of the insulin-like growth factor II mRNA-binding protein genes by architectural transcription factor ... "A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development". Mol Cell Biol. 19 ( ...

"Physiological concentrations of insulin promote binding of nuclear proteins to the insulin-like growth factor I gene". ... Wolframin is a protein that in humans is encoded by the WFS1 gene. This gene encodes a transmembrane protein, which is located ... The disease is characterized by non-immune insulin-dependent diabetes mellitus and bilateral progressive optic atrophy, usually ... "A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)". ...

Sara, V. R.; Hall, K. (July 1990). "Insulin-like growth factors and their binding proteins". Physiological Reviews. 70 (3): 591 ... Insulin growth factor-1 (IGF-1) is a hormone that is structurally very similar to insulin and mediates the effects of growth ... Laron, Z (1 October 2001). "Insulin-like growth factor 1 (IGF-1): a growth hormone". Molecular Pathology. 54 (5): 311-316. doi: ... Yamamoto, H; Murphy, L J (December 1994). "Generation of des-(1-3) insulin-like growth factor-I in serum by an acid protease". ...

"IGFALS insulin like growth factor binding protein acid labile subunit [Homo sapiens (human)]". NCBI - Gene. Retrieved 6 May ... "CCAAT/Enhancer-binding Protein Family Members Recruit the Coactivator CREB-binding Protein and Trigger Its Phosphorylation". ... As suggested by the protein's name, glutamate-rich protein 4, the protein is most highly composed of glutamic acid amino acids ... "TATA-binding proteins". InterPro. Retrieved 6 May 2019. "SRY Gene". Genetics Home Reference. Vihervaara A, Sistonen L (2014). " ...

It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. ... The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in ... CDK9 CREB-binding protein Cyclin A1 Cyclin-dependent kinase inhibitor 1C EP300 PARP1 Retinoblastoma-like protein 1 GRCh38: ... Myb-related protein B is a protein that in humans is encoded by the MYBL2 gene. ...