Loading...
*  Glucose tolerance test
Insulin levels are sometimes measured to detect insulin resistance or deficiency. The GTT (Glucose Tolerance Test) is of ... Antuna-Puente B, Disse E, Rabasa-Lhoret R, Laville M, Capeau J, Bastard JP (2011). "How can we measure insulin sensitivity/ ... Blood is drawn at intervals for measurement of glucose (blood sugar), and sometimes insulin levels. The intervals and number of ... The OGTT does not distinguish between insulin resistance in peripheral tissues and reduced capacity of the pancreas beta-cells ...
*  Insulin index
... the Insulin Index is based upon blood insulin levels. The Insulin Index represents a comparison of food portions with equal ... The Insulin Index of a food represents how much it elevates the concentration of insulin in the blood during the two-hour ... "An insulin index of foods: the insulin demand generated by 1000-kJ portions of common foods" (PDF). American Journal of ... The insulin index compares foods in amounts with equal overall caloric content (250 kcal or 1000 kJ). Insulin indexes are ...
*  Diet-induced obesity model
High levels of leptin and insulin are produced; at the same time, the body becomes resistant to both. Insulin resistance in ... For example, dogs were used as subjects in a study of the effects of diet-induced obesity on insulin dispersion. In this ... Streptozotocin inhibits the ability of pancreatic β cells to produce insulin, and depending on the dosage used, the result can ... Wang, Chao-Yung; Liao, James K. (2012-01-01). "A Mouse Model of Diet-Induced Obesity and Insulin Resistance". Methods in ...
*  Diabetes Control and Complications Trial
Prior to the DCCT, there simply was limited medical proof that the additional burden of intensive insulin therapy over the ... The intensive therapy group frequently monitored blood glucose levels and received at least three daily insulin injections; a ... The conventional diabetes therapy group received one or two daily insulin injections. ... or continuous subcutaneous insulin infusion combined with lower blood glucose targets and lower HbA1C goals. ...
*  Glucagon rescue
This might be needed in cases such as when a diabetic child is injected with insulin before breakfast, eats, and then vomits ... It is needed during seizures and/or unconsciousness by an insulin user who is unable at that point to help themselves. Glucagon ... At the first signs of hypoglycemia, an insulin user should treat it immediately by consuming carbohydrate to restore blood ... and Policies Related to Insulin and Glucagon Administration and Other Diabetes Care - American Diabetes Association "Know Your ...
*  Glucose transporter
... but it has clearly been established that insulin does not promote GLUT6 and GLUT8 cell-surface translocation. In August 1960, ...
*  Insulin analog
However, some insulin analogues, such as insulin detemir, bind to albumin rather than fat like earlier insulin varieties, and ... Basal insulin support is required throughout the day representing about 50% of daily insulin requirement, the insulin amount ... "Long-acting insulin analogues versus NPH insulin (human isophane insulin) for type 2 diabetes mellitus". Cochrane Database of ... Bovine insulin and porcine insulin may be considered as the first clinically used insulin analogs (naturally occurring, ...
*  Insulin detemir
Insulin analogues (insulin detemir and insulin aspart) versus traditional human insulins (NPH insulin and regular human insulin ... Insulin detemir is a long-acting human insulin analogue for maintaining the basal level of insulin. Novo Nordisk markets it ... Treat-to-Target Trial Comparing Insulin Detemir With NPH Insulin as Add-On Therapy to Oral Glucose-Lowering Drugs in Insulin- ... 16%, P = 0.008). Compared with NPH insulin, the risk for all hypoglycemia with insulin detemir was reduced by 47% (P < 0.001) ...
*  Intensive insulin therapy
The insulin pump is about the size of a beeper. It can be programmed to send a steady stream of insulin as basal insulin. It ... This insulin is referred to as basal insulin secretion, and constitutes almost half the insulin produced by the normal pancreas ... Long-acting insulin analogs such as insulin glargine (brand name Lantus, made by Sanofi-Aventis) and insulin detemir (brand ... These three components of the insulin regimen are commonly referred to as basal insulin, bolus insulin, and high glucose ...
*  Lifestyle causes of diabetes mellitus type 2
It secretes RBP4 which increases insulin resistance by blocking the action of insulin in muscle and liver. Fat cells also ... Inflammatory cytokines such as TNFα may activate the NF-κB pathway which has been linked to the development of insulin ... Shoelson SE, Lee J, Goldfine AB (July 2006). "Inflammation and insulin resistance". Journal of Clinical Investigation. 116 (7 ... Fat tissue has also been shown to be involved in managing much of the body's response to insulin and control of uptake of sugar ...
*  Insulin degludec
... is a modified insulin that has one single amino acid deleted in comparison to human insulin, and is conjugated ... compared to 18 to 26 hours provided by other marketed long-acting insulins such as insulin glargine and insulin detemir), ... Insulin degludec (INN/USAN) is an ultralong-acting basal insulin analogue that was developed by Novo Nordisk under the brand ... making it a once-daily basal insulin, that is one that provides a base insulin level, as opposed to the fast and short acting ...
*  Insulin
Bovine insulin differs from human in only three amino acid residues, and porcine insulin in one. Even insulin from some species ... Insulin was offered for sale shortly thereafter. Purified animal-sourced insulin was the only type of insulin available to ... In many cases of PCOS, insulin resistance is present. Biosynthetic human insulin (insulin human rDNA, INN) for clinical use is ... Serine/Threonine kinases are also known to reduce the activity of insulin. The structure of the insulin-insulin receptor ...
*  Insulin glulisine
... is a rapid-acting insulin analogue that differs from human insulin in that the amino acid asparagine at ... When injected subcutaneously, it appears in the blood earlier than human insulin. When used as a meal time insulin, the dose is ... DailyMed: apidra (insulin glulisine) injection, solution Jasek, W, ed. (2007). Austria-Codex (in German) (2007/2008 ed.). ... Drugs.com: Insulin Glulisine "Sanofi Prescription Products" (PDF). Sanofi. Retrieved 21 April 2012. ,first1= missing ,last1= in ...
*  Insulin resistance
... normally refers to reduced glucose-lowering effects of insulin. However, other functions of insulin can also ... Once established, insulin resistance would result in increased circulating levels of insulin. Since insulin is the primary ... Insulin resistance at Curlie (based on DMOZ) "The National Insulin Resistance Council". US. "Insulin resistance". Diabetes. US ... When the body produces insulin under conditions of insulin resistance, the cells are resistant to the insulin and are unable to ...
*  Insulin pump
An insulin pump is an alternative to multiple daily injections of insulin by insulin syringes or an insulin pen and allows for ... www.diabetes.co.uk/insulin/Insulin-pumps.html Insulin pumps Insulin Pumps Vulnerable to Hacking "Exclusive: Medtronic probes ... Since the basal insulin is provided as a rapid-acting insulin, the basal insulin can be immediately increased or decreased as ... Use of insulin pumps is increasing because of: Easy delivery of multiple insulin injections for those using intensive insulin ...
*  Insulin (medication)
Medical preparations of insulin are never just 'insulin in water'. Clinical insulins are specially prepared mixtures of insulin ... Insulin was formerly used in a psychiatric treatment called insulin shock therapy. If too much insulin is delivered or the ... The unit evolved eventually to the old USP insulin unit, where one unit (U) of insulin was set equal to the amount of insulin ... Patients with insulin-dependent diabetes typically require some base level of insulin (basal insulin), as well as short-acting ...
*  Insulin receptor
4548-G05 Insulin Insulin-like growth factor 1 Mecasermin Insulin receptor has been shown to interact with ENPP1, GRB10, GRB7, ... Belfiore A, Frasca F, Pandini G, Sciacca L, Vigneri R (October 2009). "Insulin receptor isoforms and insulin receptor/insulin- ... "Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin ... The insulin receptor's endogenous ligands include insulin, IGF-I and IGF-II. The binding of ligand to the α-chains of the IR ...
*  Insulin oscillation
The insulin oscillations are generated by pulsatile release of the hormone from the pancreas. Insulin originates from beta ... Disturbances of the insulin oscillations occur early in type 2 diabetes and may contribute to insulin resistance. Pulsatile ... Insulin Diabetes Hellman B, Gylfe E, Grapengiesser E, Dansk H, Salehi A (2007). "[Insulin oscillations--clinically important ... This signal is believed to entrain pulsatile insulin release from the islets into a common pancreatic rhythm. The insulin ...
*  Insulin pen
Illustration of Insulin Pen and Syringe Insulin Pen Users group Insulin Pen Reviews Insulin pump Insulin syringe Insulin port ... An insulin pen is used to inject insulin for the treatment of diabetes. Insulin is a hormone produced by the pancreas. It is ... two different insulins cannot be mixed by the user in an insulin pen. On the other hand, some of the newest types of insulin ... Timesulin is a 'smart cap' that works with all major insulin pen types to show users how long it has been since their insulin ...
*  Insulin aspart
... insulin aspart and 70% insulin aspart protamine. The insulin aspart protamine portion is a crystalline form of insulin aspart, ... The insulin in reservoirs of insulin pumps and infusion sets should be changed every 48 hours to avoid insulin degradation and ... Insulin aspart is a fast-acting insulin analog marketed by Novo Nordisk as NovoLog/NovoRapid. It is a manufactured form of ... Fast-acting insulin analogs are considered to act similarly to the way insulin is released in people without diabetes mellitus ...
*  Insulin port
To inject through an insulin port the needle of a syringe or insulin pen is used. It is usually used to deliver insulin through ... An insulin port functions as a medication delivery channel directly into the subcutaneous tissue (the tissue layer located just ... the use of an insulin pump. The needle remains above the surface of the skin, while the medication is immediately delivered ...
*  Insulin lispro
"Insulin Lispro: A Fast-Acting Insulin Analog". Retrieved 2007-06-08. Product Information: HUMALOG(R) pen injection, insulin ... Both preparations should be coupled with a longer acting insulin (e.g. NPH insulin) for good glycemic control. Insulin lispro ... Insulin lispro, sold under the brand name Humalog among others, is a fast acting insulin analog. It was first approved for use ... Do not administer insulin lispro during episodes of hypoglycemia, or if the patient has a hypersensitivity to insulin lispro or ...
*  Regular insulin
... , also known as neutral insulin and soluble insulin is a type of short acting insulin. It is used to treat ... human insulin injection [rDNA origin]) is a mixture insulin. It is an intermediate-acting insulin combined with the onset of ... human insulin injection [rDNA origin]) is a mixture insulin. It is an intermediate-acting insulin combined with the onset of ... Generic names regular insulin, insulin isophane and the Lente series consisting of Lente (known generically as insulin zinc ...
*  NPH insulin
... , also known as isophane insulin, is an intermediate-acting insulin given to help control blood sugar levels in ... There are human and pig insulin based versions. Protamine insulin was first created in 1936 and NPH insulin in 1946. It is on ... Nordisk was able to form crystals of protamine and insulin and marketed it in 1950 as NPH insulin. NPH insulin has the ... and shorter than long acting insulins (ultralente, glargine or detemir). NPH insulin may be combined with faster acting insulin ...
*  Inhalable insulin
... is a powdered form of insulin, delivered with a nebulizer into the lungs where it is absorbed, generally more ... AIR Inhaled Insulin System Human insulin inhalation powder Began Phase III trial to evaluate effectiveness in improving glucose ... In general inhaled insulins have been more rapidly absorbed than subcutaneous injected insulin, with faster peak concentration ... Afrezza, a monomeric inhaled insulin developed by Mannkind, was approved by the FDA in 2014. Insulin was introduced by Banting ...