Loading...
*  Inhibitory postsynaptic potential
An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to ... The opposite of an inhibitory postsynaptic potential is an excitatory postsynaptic potential (EPSP), which is a synaptic ... The size of the neuron can also affect the inhibitory postsynaptic potential. Simple temporal summation of postsynaptic ... An electric current that changes the postsynaptic membrane potential to create a more negative postsynaptic potential is ...
*  Excitatory synapse
"Excitatory and Inhibitory Postsynaptic Potentials". Sinauer Associates, Inc. 2001. J. Rand (2007). "Acetylcholine". Stephen ... the postsynaptic cell will be more likely to generate an action potential and an excitatory postsynaptic potential will occur ( ... an inhibitory postsynaptic potential will occur (IPSP). Although the receptors at an excitatory synapse strive to bring the ... This phenomenon is known as an excitatory postsynaptic potential (EPSP). It may occur via direct contact between cells (i.e., ...
*  Action potential
Their joint efforts can be thwarted, however, by the counteracting inhibitory postsynaptic potentials. Neurotransmission can ... Action potentials are most commonly initiated by excitatory postsynaptic potentials from a presynaptic neuron. Typically, ... The action potential in a normal skeletal muscle cell is similar to the action potential in neurons. Action potentials result ... This all-or-nothing property of the action potential sets it apart from graded potentials such as receptor potentials, ...
*  Synaptic potential
... comes in two forms: excitatory and inhibitory. Excitatory post-synaptic potentials (EPSPs) depolarize the ... This is the case for both excitatory and inhibitory postsynaptic potentials. Synaptic potentials are not static. The concept of ... Inhibitory postsynaptic potentials (IPSPs) hyperpolarize the membrane and move it farther away from the threshold. In order to ... Synaptic potential refers to the difference in voltage between the inside and outside of a postsynaptic neuron. In other words ...
*  Ventrobasal complex
If the receptor is located postsynaptically then when activated the receptor causes Inhibitory postsynaptic potential. When ... mu Opioid receptor (MORs) are inhibitory receptors that can cause a decrease in pain if activated and are expressed in the VB ... Decrease in pain related behaviors can be attributed to the activation of MORs in the VB which activates an inhibitory circuit ...
*  Biological neural network
Excitatory and inhibitory synaptic transmission is realized mostly by inhibitory postsynaptic potentials and excitatory ... strongly on the relative timing of the onset of the excitatory postsynaptic potential and the postsynaptic action potential. ... One principle by which neurons work is neural summation, i.e. potentials at the post synaptic membrane will sum up in the cell ... These simple models accounted for neural summation (i.e., potentials at the post-synaptic membrane will summate in the cell ...
*  GABA receptor
As a result, further GABA binding becomes inhibited and inhibitory postsynaptic potentials are no longer relevant. However, the ... Takeuchi A, Takeuchi N (August 1967). "Anion permeability of the inhibitory post-synaptic membrane of the crayfish ... The increased chloride conductance drives the membrane potential towards the reversal potential of the Cl¯ ion which is about - ... The controversy arose when a number of studies have shown that GABA in neonatal brain slices becomes inhibitory if glucose in ...
*  Stimulus (physiology)
This neurotransmitter causes an inhibitory postsynaptic potential in the postsynaptic neuron. This response will cause the ... In excitatory postsynaptic potentials, an excitatory response is generated. This is caused by an excitatory neurotransmitter, ... If a graded potential is strong enough, or if several graded potentials occur in a fast enough frequency, the depolarization is ... If a signal from the presynaptic neuron is inhibitory, inhibitory neurotransmitters, normally GABA will be released into the ...
*  Onchocerciasis
... eventually causing an inhibitory postsynaptic potential. The chance of a future action potential occurring in synapses between ... by enhancing inhibitory neurotransmission. The drug binds to and activates glutamate-gated chloride channels. These channels, ...
*  Glycine
... causing an Inhibitory postsynaptic potential (IPSP). Strychnine is a strong antagonist at ionotropic glycine receptors, whereas ... Glycine is an inhibitory neurotransmitter in the central nervous system, especially in the spinal cord, brainstem, and retina. ... In contrast to the inhibitory role of glycine in the spinal cord, this behaviour is facilitated at the (NMDA) glutamatergic ...
*  Joro toxin
... or inhibitory postsynaptic potentials. Kawai, Nobufumi; Niwa, Akiko; Abe, Takashi (1982). "Spider venom contains specific ... The compound has demonstrated the ability to selectively block postsynaptic glutamate potentials, AMPA glutamate receptors, and ... However, it does not affect aspartate-induced neural depolarization, resting membrane potential, nerve terminal spontaneous ...
*  Gelsemine
At lower doses in humans, the inhibitory postsynaptic potential induced by gelsemine action at the glycine receptor can result ... the activation of which leads to an inhibitory postsynaptic potential in neurons following chloride ion influx, and ... chloride ions enter the neuron causing an inhibitory postsynaptic potential, which, systemically, leads to muscle relaxation.[ ... 2014). "Potential Role of Allopregnanolone for a Safe and Effective Therapy of Neuropathic Pain". Prog Neurobiol. 113 (February ...
*  Olfactory bulb
... to pre-synaptic action potentials and exhibit both excitatory postsynaptic potentials and inhibitory postsynaptic potentials. ... Its potential functions can be placed into four non-exclusive categories:[citation needed] discriminating among odors enhancing ... The granule cell in turn releases GABA to cause an inhibitory effect on the mitral cell. More neurotransmitter is released from ... and granule cells release the inhibitory neurotransmitter Gamma-aminobutyric acid (GABA). As a result of its bi-directionality ...
*  Summation (neurophysiology)
... whereas summation of inhibitory postsynaptic potentials can prevent the cell from achieving an action potential. The closer the ... Summation of excitatory postsynaptic potentials increases the probability that the potential will reach the threshold potential ... In contrast to glutamate, the neurotransmitter GABA mainly functions to trigger inhibitory postsynaptic potentials (IPSPs) in ... Their work showed that spatial summation of excitatory and inhibitory postsynaptic potentials caused attenuation of the ...
*  Synaptic noise
These random potentials have similar time courses as excitatory postsynaptic potentials (EPSPs) and inhibitory postsynaptic ... Noise is observed as changes in the membrane potential of a cell. The change in potential causes the accuracy of a neuron to be ... This occurs in the background of a cell when potentials are produced without the nerve stimulation of an action potential, and ... In an action potential, calcium channels are opened by depolarization and release Ca2+ ions into the presynaptic cell. This ...
*  Motion sensing in vision
... their null direction with a simultaneous small excitatory postsynaptic potential and a large inhibitory postsynaptic potential ... The DS ganglion cells respond to their preferred direction with a large excitatory postsynaptic potential followed by a small ... chloride-ion equilibrium potential relative to the resting potential while others have a negative equilibrium potential. This ... Such postsynaptic models are unparsimonious, and so if any given starburst amacrine cells conveys motion information to retinal ...
*  Metabotropic glutamate receptor
Receptors in groups II and III reduce the activity of postsynaptic potentials, both excitatory and inhibitory, in the cortex. ... but they also increase inhibitory postsynaptic potentials, or IPSPs. They can also inhibit glutamate release and can modulate ... These receptors are involved in presynaptic inhibition, and do not appear to affect postsynaptic membrane potential by ... For example, one study found that Group I mGluRs are located mostly on postsynaptic parts of cells, while groups II and III are ...
*  Excitatory postsynaptic potential
These are the opposite of inhibitory postsynaptic potentials (IPSPs), which usually result from the flow of negative ions into ... In neuroscience, an excitatory postsynaptic potential (EPSP) is a postsynaptic potential that makes the postsynaptic neuron ... This temporary depolarization of postsynaptic membrane potential, caused by the flow of positively charged ions into the ... generating an excitatory postsynaptic current. This depolarizing current causes an increase in membrane potential, the EPSP. ...
*  John Eccles (neurophysiologist)
... an inhibitory postsynaptic potential (IPSP) is produced in the quadriceps motor neuron. Although a single EPSP was not enough ... the motor neuron innervating the quadriceps produced a small excitatory postsynaptic potential (EPSP). When a similar current ... 1969, The Inhibitory Pathways of the Central Nervous System. 1970, Facing reality: Philosophical Adventures by a Brain ... to fire an action potential in the motor neuron, the sum of several EPSPs from multiple sensory neurons synapsing onto the ...
*  Postsynaptic potential
This is an inhibitory postsynaptic potential (IPSP), as it changes the charge across the membrane to be further from the firing ... Postsynaptic potentials are changes in the membrane potential of the postsynaptic terminal of a chemical synapse. Postsynaptic ... Membrane potential Nernst equation Neuron Neurotransmission Postsynaptic Synapse End-plate potential Postsynaptic Potentials at ... as the potential comes closer to zero. This is an excitatory postsynaptic potential (EPSP), as it brings the neuron's potential ...
*  Non-spiking neuron
Transduction (biophysics) EPSP(excitatory post-synaptic potential) IPSP (inhibitory post-synaptic potential). Hikosaka, R; ... The change from a cell that can generate action potentials to solely functioning off of a graded potential is drastic, and may ... These neurons use a graded potential to transmit data as they lack the membrane potential that spiking neurons possess. This ... and the post-synaptic cell was given an inhibitory signal. The interaction between the two cells was modulatory in which the ...
*  Scratch reflex
These inputs include inhibitory postsynaptic potentials (IPSPs) and excitatory postsynaptic potentials (EPSPs), meaning that ...
*  Losigamone
... but has no significant influence on GABAergic inhibitory postsynaptic potentials in hippocampal slices. Interaction with ...
*  Nonsynaptic plasticity
... and inhibitory postsynaptic potentials (IPSPs). Nonsynaptic plasticity is a modification of the intrinsic excitability of the ... Every excitatory postsynaptic potential that is propagated to a postsynaptic cell is first transmitted through the action ... It is known that changes in dendritic excitability affect action potential back propagation. Action potentials begin near the ... the response of the excitatory postsynaptic potential through neurotransmitter release and augmentation of the action potential ...
*  Axon hillock
Both inhibitory postsynaptic potentials (IPSPs) and excitatory postsynaptic potentials (EPSPs) are summed in the axon hillock ... This initiates an action potential that then propagates down the axon. As sodium enters the cell, the cell membrane potential ... resulting in an intracellular fluid that is more negative than the resting potential, and during which no action potential can ... As the action potential reaches a node of Ranvier, it depolarises the cell membrane. As the cell membrane is depolarised, the ...
*  Pre-Bötzinger complex
In CS pacemakers, NE increases only the amplitude of the depolarizing drive potential and the number of action potentials ... Glycinergic and GABAergic inhibitory neurons make up half of all inspiratory neurons. Exposure of the pre-Bötzinger complex to ... P/Q-type calcium channels are mainly responsible for the release of neurotransmitters that excite, or activate, postsynaptic ... which allows neurons to intrinsically fire action potentials at sub-threshold membrane potentials. Studies have shown that the ...