EP300-interacting inhibitor of differentiation 1 is a protein that in humans is encoded by the EID1 gene. EID1 has been shown ... 2005). "Binding of pRB to the PHD protein RBP2 promotes cellular differentiation". Mol. Cell. 18 (6): 623-35. doi:10.1016/j. ... "Entrez Gene: EID1 EP300 interacting inhibitor of differentiation 1". Miyake, S; Sellers W R; Safran M; Li X; Zhao W; Grossman S ... 2000). "Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle". Mol. Cell. ...

β-Glycerophosphate is an inhibitor of the enzyme serine-threonine phosphatase. It is often used in combination with other ... β-Glycerophosphate is also used to drive osteogenic differentiation of bone marrow stem cells in vitro. β-Glycerophosphate is ... used to buffer M17 media for Lactococcus culture in recombinant protein expression. "β-Glycerophosphate disodium salt hydrate ... "Protease and Phosphatase Inhibitors". Thermo Fisher Scientific. Retrieved 2018-05-30. Langenbach & Handschel (2013). "Effects ...

Cryptic family protein 1B is a protein that in humans is encoded by the CFC1B gene. Cryptic family protein 1B acts as a ... and a block on the differentiation of cardiac myocyte,. both of which lead to embryonic death. Cripto's functions have been ... Expression levels of cripto are associated with resistance to EGFR inhibitors. Teratocarcinoma-derived growth factor 1 GRCh38: ... It has been associated with the translation of an extracellular protein for this pathway. The extracellular protein which ...

Bae S, Bessho Y, Hojo M, Kageyama R (2000). "The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation". ... The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box promoter ... "Modulation of basic helix-loop-helix transcription complex formation by Id proteins during neuronal differentiation". J. Biol. ... has been shown to induce neural differentiation, and HES1 binding of Dll1 blocks neural differentiation and leads to the ...

Cluster of Differentiation 115), is a cell-surface protein encoded by the human CSF1R gene (known also as c-FMS). CSF1R is a ... Overall, CSF1R inhibitors have favorable safety profiles with limited toxicity. CSF1R inhibitors such as PLX5622 are widely ... protein, an inhibitor of pro-apoptotic caspase-9. CSF1R signaling in mature osteoclasts promotes survival by stimulating mTOR/ ... CSF1R, the protein encoded by the CSF1R gene is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor ...

... soluble translational inhibitor protein from human monocytes that is upregulated upon cellular differentiation". Eur J Biochem ... 1999). "Ribonuclease activity of rat liver perchloric acid-soluble protein, a potent inhibitor of protein synthesis". J. Biol. ... 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode: ... 1996). "Isolation and characterization of a novel perchloric acid-soluble protein inhibiting cell-free protein synthesis". J. ...

"The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins". Cell. 83 ... is required for cell differentiation". Cell Death Differ. 15 (5): 859-66. doi:10.1038/cdd.2008.5. PMID 18239673. Verhagen AM, ... Rajcan-Separovic E, Liston P, Lefebvre C, Korneluk RG (1997). "Assignment of human inhibitor of apoptosis protein (IAP) genes ... Baculoviral IAP repeat-containing protein 2 (also known as cIAP1) is a protein that in humans is encoded by the BIRC2 gene. ...

"Interaction of heat-shock protein 90 beta isoform (HSP90 beta) with cellular inhibitor of apoptosis 1 (c-IAP1) is required for ... cell differentiation". Cell Death and Differentiation. 15 (5): 859-66. doi:10.1038/cdd.2008.5. PMID 18239673. Sekine K, Takubo ... "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi:10.1016/j.cell ... Polyubiquitin-C is a protein encoded by the UBC gene in humans. Polyubiquitin-C is one of the sources of ubiquitin, along with ...

One example is the BMP (bone morphogenetic protein,) which has an important role in ameloblast differentiation. When ... Follistatin, a BMP inhibitor, is over expressed in the epithelium of developing teeth, the ameloblasts do not differentiate and ... Their differentiation from preameloblasts (whose origin is from inner enamel epithelium) is a result of signaling from the ... The differentiation from preameloblasts to ameloblasts occurs during the first stage of amelogenesis, called the pre-secretory ...

... a novel protein with protease inhibitor and follistatin domains". Molecular Endocrinology. 17 (6): 1144-54. doi:10.1210/me.2002 ... "Regulation of myostatin in vivo by growth and differentiation factor-associated serum protein-1: ... This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, ... purification and characterization of the second Kunitz-type protease inhibitor domain of the human WFIKKN protein". European ...

... (also known as 14-3-3 protein sigma or 14-3-3σ protein) is a protein encoded by the SFN gene in humans. The protein ... Differentiation. 3 (8): 507-13. PMID 1390337. Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, Thiagalingam S, Kinzler KW, ... Vogelstein B (December 1997). "14-3-3sigma is a p53-regulated inhibitor of G2/M progression". Molecular Cell. 1 (1): 3-11. doi: ... A member of a protein family that has been involved in the protein kinase C signalling pathway". Journal of Molecular Biology. ...

... bone morphogenetic proteins, growth and differentiation factors, and Müllerian inhibitor subfamily. TGF-β signaling plays an ... The second is the helix-loop-helix (HLH) region, which facilitates protein-protein interactions. Also contained with the AhR ... also known as hepatitis B virus X-associated protein 2 (XAP2), AhR interacting protein (AIP), and AhR-activated 9 (ARA9). The ... The AhR protein contains several domains critical for function and is classified as a member of the basic helix-loop-helix/Per- ...

... differentiation, mitosis, cell survival or apoptosis. cIAP1 is as well implicated in innate immunity. When NOD-like receptors ... cIAP1 (also named BIRC2) is the abbreviation for a human protein, cellular inhibitor of apoptosis protein-1. It belongs to the ... cIAP1 is an inhibitor of apoptosis protein. It directly ubiquitinates RIP1 and induces constitutive RIP1 ubiquitination in ... Pu Xia; Yanfei Qi (2012). "Cellular Inhibitor of Apoptosis Protein-1 (cIAP1) Plays a Critical Role in β-Cell Survival under ...

Inhibitor of DNA-binding/differentiation proteins, also known as ID proteins comprise a family of proteins that heterodimerize ... Differentiation+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Enzyme inhibitors, Protein ... By inhibiting the formation of E-protein dimers that promote differentiation, ID proteins can regulate the timing of ... ID proteins can bind E-proteins, preventing them from binding bHLH proteins and halting transcription, a case often seen in ...

2009). "Correlation of inhibitor of differentiation 1 expression to tumor progression, poor differentiation and aggressive ... Ducy P, Karsenty G (2000). "The family of bone morphogenetic proteins". Kidney Int. 57 (6): 2207-14. doi:10.1046/j.1523- ... Growth differentiation factor 1 (GDF1) is a protein that in humans is encoded by the GDF1 gene. GDF1 belongs to the ... Rankin CT, Bunton T, Lawler AM, Lee SJ (March 2000). "Regulation of left-right patterning in mice by growth/differentiation ...

"Downregulation of cAMP-dependent protein kinase inhibitor gamma is required for BMP-2-induced osteoblastic differentiation". ... cAMP-dependent protein kinase inhibitor gamma is a protein that in humans is encoded by the PKIG gene. The protein encoded by ... 2002). "Protein inhibitor of neuronal nitric oxide synthase interacts with protein kinase A inhibitors". Brain Res. Mol. Brain ... inhibitor family. Studies of a similar protein in mice suggest that this protein acts as a potent competitive PKA inhibitor, ...

Known interactions are with proteins such as Oligodendrocyte-myelinn glycoprotein, Nogo-A (neurotic outgrowth inhibitor), and ... a transmembrane signaling protein, inhibits oligodendrocyte differentiation and myelination through intercellular self- ... The C-terminal LRR domain is essential for the protein's function with its screening for proteins that interact with this ... amyloid precursor protein (APP), and tropomyosin receptor kinase A (TrkA). There are other interactions with proteins that are ...

... proteins BRD2, BRD3, BRD4, and BRDT, and prevent protein-protein interaction between BET proteins and acetylated histones and ... to affect the differentiation of oligodendrocyte progenitor cells.: 4.1 RVX-208 ABBV-744 LY294002 (some PI3K and BRD2, BRD3, ... BET inhibitors have been described that are able to discriminate between the first and second bromodomains of BET proteins (BD1 ... Examples include use of BET inhibitors in combination with γ-secretase inhibitors for T cell acute lymphoblastic leukemia and ...

"RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small ... Cell Death and Differentiation. 7 (1): 25-36. doi:10.1038/sj.cdd.4400616. PMID 10713718. Liu Ax, Du W, Liu JP, Jessell TM, ... "RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small ... Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene. RHOB is a ...

Endogenous inhibitors or activators generated by proteolytic degradation of larger proteins mostly from the ECM have proven to ... Inhibitors of MMP activity have spotlighted the importance of these proteins in controlling angiogenesis. Recently, it has been ... and by endogenous inhibitors known as tissue inhibitors of metalloproteinases (TIMPs). The role of matrix metalloproteinases ... "Structure-function analysis of the ADAM family of diintegrin-like and metalloproteinase-containing proteins". J. Protein Chem. ...

Moldes M, Boizard M, Liepvre XL, Fève B, Dugail I, Pairault J (Dec 1999). "Functional antagonism between inhibitor of DNA ... and adipocyte determination and differentiation factor 1/sterol regulatory element-binding protein-1c (ADD1/SREBP-1c) trans- ... The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. SREBP-1a regulates ... SREBF1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) FactorBook SREBP1 This article ...

DNA-binding protein inhibitor ID-3 is a protein that in humans is encoded by the ID3 gene. Members of the ID family of helix- ... Selective antagonism of E2A basic helix-loop-helix protein associated with Id3-induced differentiation of erythroleukemia cells ... "Entrez Gene: ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein". Deed RW, Jasiok M, Norton JD (Apr ... Inhibitor of DNA-binding protein ENSG00000117318 GRCh38: Ensembl release 89: ENSG00000283060, ENSG00000117318 - Ensembl, May ...

... function as an activating coreceptor in B-cells may function in B-cell activation and differentiation MEI1-meiosis inhibitor 1 ... "TMEM156 - Transmembrane protein 156 - human protein (Proteomics)". www.nextprot.org. Retrieved 2016-04-27. "PSORT WWW Server". ... "TMEM156 - Transmembrane protein 156 - human protein (Proteomics)". www.nextprot.org. Retrieved 2016-05-04. "TopPred". mobyle. ... The TMEM156 protein is 296 amino acids in length. It has a molecular weight of 34.323 kDa and an isoelectric point of 7.98. The ...

Natural protease inhibitors include the family of lipocalin proteins, which play a role in cell regulation and differentiation ... Other natural protease inhibitors are used as defense mechanisms. Common examples are the trypsin inhibitors found in the seeds ... The natural protease inhibitors are not to be confused with the protease inhibitors used in antiretroviral therapy. Some ... The activity of proteases is inhibited by protease inhibitors. One example of protease inhibitors is the serpin superfamily. It ...

Inhibitors of these ligands prevents mesoderm formation and these proteins show a graded distribution along the dorsal/ventral ... mom-2 is a member of the Wnt family of proteins (i.e. the signal) and mom-5 is a member of the frizzled family of proteins (i.e ... These proteins are known to be ligands for the Notch protein. GLP-1, a Notch protein, is also required for specification of the ... Wnt proteins were not necessary to specify the axis, but examination of other proteins in the Wnt pathway led to the discovery ...

"Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins". Genes ... DNA-binding protein inhibitor ID-1 is a protein that in humans is encoded by the ID1 gene. The protein encoded by this gene is ... "The MyoD-inducible p204 protein overcomes the inhibition of myoblast differentiation by Id proteins". Molecular and Cellular ... This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different ...

... has been shown to interact with protein C inhibitor. Prostate-specific antigen interacts with and ... May 1998). "Use of the percentage of free prostate-specific antigen to enhance differentiation of prostate cancer from benign ... Christensson A, Lilja H (February 1994). "Complex formation between protein C inhibitor and prostate-specific antigen in vitro ... Most PSA in the blood is bound to serum proteins. A small amount is not protein-bound and is called 'free PSA'. In men with ...

"An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein". Journal of ... Differentiation. 12 (1): 29-37. PMID 11205743. Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, ... The eukaryotic proteasome recognized degradable proteins, including damaged proteins for protein quality control purpose or key ... Proteasome subunit alpha type-6 is a protein that in humans is encoded by the PSMA6 gene. This protein is one of the 17 ...

"An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein". Journal of ... during growth and differentiation of human hematopoietic cells". The Journal of Biological Chemistry. 267 (25): 18100-9. doi: ... The eukaryotic proteasome recognized degradable proteins, including damaged proteins for protein quality control purpose or key ... The protein is 30 kDa in size and composed of 263 amino acids. The calculated theoretical pI of this protein is 6.15. The ...

... , a protein, is a stoichiometric inhibitor of Cdk1-Clb (B-type cyclins) complexes in the budding yeast Saccharomyces ... Low p27Kip1 expression can lead to tumor de-differentiation, increased penetration through the gastric wall, lymph node ... Thus, the human Cdk inhibitor p27Kip1 is a potential tumor suppressor protein. If its expression is reduced, the result might ... Page of Sic1 at yeastgenome.org (Protein pages needing a picture, Cell cycle, Saccharomyces cerevisiae genes, Proteins). ...