Induced pluripotent stem cells are similar to natural pluripotent stem cells, such as embryonic stem cells, in many aspects, ... claim of pluripotent stem cell generation by immersing cells in an acid Induced pluripotent stem cells vs embryonic stem cells ... Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated ... July 2010). "Reprogramming of human peripheral blood cells to induced pluripotent stem cells". Cell Stem Cell. 7 (1): 20-4. doi ...
The European Bank for induced pluripotent Stem Cells (EBiSC) is a non-profit induced pluripotent stem cell (iPSC) biorepository ... "Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience". Stem Cell ... "Development and implementation of large-scale quality control for the European bank for induced Pluripotent Stem Cells". Stem ... "European Bank for induce pluripotent Stem Cells". CORDIS: EU Research Results. EU Publications Office. Retrieved 20 July 2020 ...
niccolox (2015-02-26). "Induced Pluripotent Stem Cell Repository". California's Stem Cell Agency. Retrieved 2021-10-20. "NIA". ... induced pluripotent stem cell (iPSC) repository is an effort to create a collection of stem cells from thousands of different ... The Allen Institute for Cell Science Cell Collection is a collection of fluorescently tagged, human, induced pluripotent stem ... "A Resource for Stem Cells including iPSCs and Fibroblasts , The NINDS Human Cell and Data Repository". nindsgenetics.org. ...
Stem cell Embryonic stem cell Induced pluripotent stem cell Induced stem cells Adult stem cell Cell culture Immortalised cell ... unlike pluripotent embryonic stem cells). Types of adult stem cells include hematopoietic stem cells and mesenchymal stem cells ... Induced pluripotent stem cell (iPSC) lines are pluripotent stem cells that have been generated from adult/somatic cells. The ... embryonic stem cells, adult stem cells, or induced stem cells. They are commonly used in research and regenerative medicine. By ...
Mobley AS (January 2019). "Chapter 4 - Induced Pluripotent Stem Cells". In Mobley AS (ed.). Neural Stem Cells and Adult ... There is therefore a direct link to how actively productive a cell is and the amount of euchromatin that can be found in its ... It is thought that the cell uses transformation from euchromatin into heterochromatin as a method of controlling gene ... ISBN 978-0-12-811014-0. "The cell. 4. Nucleus. Chromatin. Atlas of plant and animal histology". mmegias.webs.uvigo.es. ...
Not all stem cell research involves human embryos. For example, adult stem cells, amniotic stem cells, and induced pluripotent ... "Best Hope Lies in Private Stem-Cell Funding". Retrieved 2008-01-31. "California's Stem Cell Agency". California's Stem Cell ... "Research and therapy with induced pluripotent stem cells (IPSCs): Social, legal, and ethical considerations". Stem Cell ... Induced pluripotent stem cells are those derived from adult somatic cells and have the potential to provide an alternative for ...
Xu W, Cox CS, Li Y (2011). "Induced pluripotent stem cells for peripheral nerve regeneration". Journal of Stem Cells. 6 (1): 39 ... Sayad Fathi S, Zaminy A (September 2017). "Stem cell therapy for nerve injury". World Journal of Stem Cells. 9 (9): 144-151. ... "Mesenchymal stem cells to treat diabetic neuropathy: a long and strenuous way from bench to the clinic". Cell Death Discovery. ... Stem-cell therapy is also being looked at as a possible means to repair peripheral nerve damage, however efficacy has not yet ...
... can be used as one of the four factors used in reprogramming somatic cells to induced pluripotent stem cells. The three ... at the one cell stage and it can be used to promote direct reprogramming of somatic cells to induced pluripotent stem cells, ... "Induction of pluripotent stem cells from adult human fibroblasts by defined factors". Cell. 131 (5): 861-72. doi:10.1016/j.cell ... Okita K, Ichisaka T, Yamanaka S (July 2007). "Generation of germline-competent induced pluripotent stem cells". Nature. 448 ( ...
... induced pluripotent stem cells (iPSCs), from adult cells. These are not adult stem cells, but somatic cells (e.g. epithelial ... Mesenchymal stem cell Ovarian stem cell Partial cloning Plant stem cell Stem cell controversy Stem cell marker Stem cell laws ... mesenchymal stem cell, adipose-derived stem cell, endothelial stem cell, dental pulp stem cell, etc.). Muse cells (multi- ... fetal proper stem cells, induced pluripotent stem cells. Fetal proper stem cells form tumors despite multipotency. Ethical ...
All of these cells have different, specialized functions, but they all came from one pluripotent cell. Induced pluripotent stem ... as in being able to differentiate into different cell types in the case of pluripotent stem cells. One type of pluripotent cell ... This stem cell can produce red blood cells, platelets, mast cells, dendritic cells, macrophages, lymphocytes, neutrophils, ... TH2 cells produce cytokines that will trigger certain B cells. B cells can differentiate into memory cells or plasma cells. The ...
Induced Pluripotent Stem Cells (iPSCs)". Journal of Stem Cells. 10 (1): 43-62. PMID 26665937. Takeda Y, Harada Y, Yoshikawa T, ... is claimed to increase the proliferation of inner ear stem cells, potentially allowing regrowth of the hair cells which are ... "Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using a GSK3 inhibitor", ... "Clonal Expansion of Lgr5-Positive Cells from Mammalian Cochlea and High-Purity Generation of Sensory Hair Cells". Cell Reports ...
May 2011). "Modelling schizophrenia using human induced pluripotent stem cells". Nature. 473 (7346): 221-225. Bibcode:2011Natur ... The differentiation of stem cell precursors into specialized neurons gives rise to the formation of synapses and neural ... Stem Cell Research. 12 (1): 101-118. doi:10.1016/j.scr.2013.09.014. PMC 3947234. PMID 24157591. Verstraelen, Peter; Garcia-Diaz ... 2002). Molecular Biology of the Cell (4th ed.). Garland Science. Patel, Tapan P.; Man, Karen; Firestein, Bonnie L.; Meaney, ...
... generation of induced pluripotent stem cells (iPS cells), tumor heterogeneity and emergence of cancer stem cells from non-stem ... Yamanaka, Shinya (2009). "Elite and stochastic models for induced pluripotent stem cell generation". Nature. Springer Science ... and KLF4 that induce reprogramming of pluripotent stem (iPS) cells, and >90% of the Cancer/Testis Antigens several of which are ... "Protein intrinsic disorder and induced pluripotent stem cells". Molecular BioSystems. Royal Society of Chemistry (RSC). 8 (1): ...
... and patient derived induced pluripotent stem cells (iPSC). Immortalized cell lines are cells from an organism which have been ... Patient-derived induced pluripotent stem cell (iPSC) lines are unique in which differentiated somatic cells are taken from ... "iPS Cells Collection". The Jackson Laboratory. Retrieved 2022-11-28. "NIA Collection - Induced Pluripotent Stem Cells". www. ... "Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells". Nature. 482 (7384): 216-220. Bibcode: ...
"Human-induced pluripotent stem cells in modeling inherited cardiomyopathies". Journal of the Practice of Cardiovascular ... Shantanu Sengupta is an Indian cell biologist and a professor at the Institute of Genomics and Integrative Biology (IGIB) of ... Indian cell biologists, Year of birth missing (living people)). ...
August 2013). "Induced pluripotent stem cells from human hair follicle mesenchymal stem cells". Stem Cell Reviews and Reports. ... July 2010). "Reprogramming of human peripheral blood cells to induced pluripotent stem cells". Cell Stem Cell. 7 (1): 20-4. doi ... May 2014). "Human finger-prick induced pluripotent stem cells facilitate the development of stem cell banking". Stem Cells ... "Induced pluripotent stem cells: past, present, and future". Cell Stem Cell. 10 (6): 678-684. doi:10.1016/j.stem.2012.05.005. ...
Autologous induced pluripotent stem cell-derived four-organ-chip. Future Science OA 5(8): FSO413. U. Marx, T.B. Andersson, A. ... Uwe Marx's team at TissUse GmbH has also succeeded in generating different human organoids for induced pluripotent stem cells ( ... 1992). Simultaneous cultivation of two hybridoma cell lines in a hollow fiber bioreactor. Animal Cell Technology 534-537. doi: ... Animal Cell Technology: Basic & Applied Aspects. The Sixth International Meeting of the Japanese Association for Animal Cell ...
"Generation of Induced Pluripotent Stem Cells from Mammalian Endangered Species". Cell Reprogramming. Methods in Molecular ... "Induced pluripotent stem cells from highly endangered species" (PDF). Nature Methods. 8 (10): 829-31. doi:10.1038/nmeth.1706. ... one of the first two animals of an endangered species to have his tissue samples used to make induced pluripotent stem cells as ... 2016 Stem cell research could save endangered rhinos and monkeys, by Janet Fang; at ZDNet; published September 7, 2011; ...
May 2023). "Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques". ... Ohnuki M, Takahashi K (October 2015). "Present and future challenges of induced pluripotent stem cells". Philosophical ... or other cell types such as mesenchymal stem cells. Synoviocytes, which are the predominant cell type in the synovium are ... The harvested cells also need to be manipulated in a sterile manner and care must be taken to not damage the cells or their ...
Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells , Science doi:10.1126/science.1151526 , PMID 18029452 "UW- ... achieved the production of induced pluripotent stem cells by genetic reprogramming of human dermal fibroblasts (from a baby's ... in developing novel method of reprogramming adult cells to create pluripotent cells which are not from embryonic stem cells. In ... in Thomson's lab achieves genetic reprogramming of human skin cells to create cells indistinguishable from embryonic stem cells ...
FCDI) is a large scale manufacturer of human cells, created from induced pluripotent stem cells, for use in basic research, ... January 15, 2009). "Induced pluripotent stem cells from a spinal muscular atrophy patient". Nature. 457 (7227): 277-280. ... "Generation and characterization of high-quality, footprint-free human induced pluripotent stem cell lines from 3,000 donors to ... "Medical College of Wisconsin and Cellular Dynamics Awarded NHLBI Grant Using Human Induced Pluripotent Stem Cells" (Press ...
Taylor CJ, Bolton EM, Bradley JA (August 2011). "Immunological considerations for embryonic and induced pluripotent stem cell ... The T-cells of umbilical cord blood (UCB) have an inherent immunological immaturity, and the use of UCB stem cells in unrelated ... GvHD is commonly associated with bone marrow transplants and stem cell transplants. White blood cells of the donor's immune ... cells in the graft itself that causes it but cells in the graft that make the recipient's T cells act like donor T cells. It ...
Taylor CJ, Bolton EM, Bradley JA (August 2011). "Immunological considerations for embryonic and induced pluripotent stem cell ... it can stimulate B-cells that also recognize the same molecule in their B-cell receptors. Thus, T-cells help B-cells make ... T-cells have receptors that are similar to B-cell receptors, and each T-cell recognizes only a few MHC class II-peptide ... Major MHC class II proteins only occur on antigen-presenting cells, B cells, and T cells. HLA-DP α-chain encoded by HLA-DPA1 ...
"Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells". Science. 318 (5858): 1917-20. Bibcode:2007Sci...318.1917 ... "Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors". Cell. 131 (5): 861-72. doi:10.1016/j.cell ... Human embryonic stem cells are pluripotent, that is, they can differentiate into any of the cell types present in the adult ... In the laboratory, human embryonic stem cells growing in culture can be induced to differentiate into progenitor cells by ...
The first induced pluripotent human stem cells were made in 2006, allowing adult cells to be transformed into stem cells and ... Rashid, S. Tamir; Alexander, Graeme J.M. (March 2013). "Induced pluripotent stem cells: from Nobel Prizes to clinical ... turn to any cell type found in the body. With the affirmation of the Higgs boson discovery in 2013, the last particle predicted ...
Okita K, Ichisaka T, Yamanaka S (July 2007). "Generation of germline-competent induced pluripotent stem cells". Nature. 448 ( ... 2006 Creation of induced stem cells (iSC) from somatic cells by the simultaneous action of several factors. First produced by ... "Induction of pluripotent stem cells from adult human fibroblasts by defined factors". Cell. 131 (5): 861-872. doi:10.1016/j. ... "Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors". Cell. 126 (4): 663- ...
... induces myofibrillar disarray and contractile vector variability in hypertrophic cardiomyopathy-induced pluripotent stem cell- ... naturally-occurring or transgenic animal models and more recently disease modeling using induced pluripotent stem cells (iPSC)- ... "Study familial hypertrophic cardiomyopathy using patient-specific induced pluripotent stem cells". Cardiovascular Research. 104 ... Cell Stem Cell. 12 (1): 101-13. doi:10.1016/j.stem.2012.10.010. PMC 3638033. PMID 23290139. Han L, Li Y, Tchao J, Kaplan AD, ...
"The polycomb protein Ezh2 impacts on induced pluripotent stem cell generation". Stem Cells and Development. 23 (9): 931-940. ... In particular, it helps control transcriptional repression of genes that regulate cell differentiation. In embryonic stem cells ... De Haan G, Gerrits A (June 2007). "Epigenetic control of hematopoietic stem cell aging the case of Ezh2". Annals of the New ... December 2012). "Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during ...
Recent research has used induced pluripotent stem cells to study disease mechanisms in humans, and discovered that the ... March 2010). "Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients". Nature. 464 (7286): ... Dyskeratosis Congenita in regards to stem cell transplantation have to be very carefully treated with low intensity radiation/ ... The mainstay of treatment in dyskeratosis congenita is hematopoietic stem cell transplantation, best outcome with sibling donor ...
Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells. Cell Stem Cell 2009, 4:141-154. Deng Z ... In cells that lack telomerase expression, it is well-established that most cells instead maintain the ends of their telomeres ... Mol Cell Biol 2010, 30:4808-4817. Claus M. Azzalin & Joachim Lingner (2008) Telomeres: The silence is broken, Cell Cycle, 7:9, ... In general, TERRA has been shown to be most abundant in cells with long telomeres, while cells with short telomeres express ...
A functionally characterized test set of human induced pluripotent stem cells. Nature Biotechnology, 29, 279-286. "MCO Graduate ... She then worked as a senior research technician and lab manager at the Project A.L.S. Laboratory for Stem Cell Research at ... Hynek Wichterle, Mathis modelled amyotrophic lateral sclerosis (A.L.S.) using stem cell-derived motor neurons. During her time ... and the other in Nature Biotechnology on benchmarking iPS stem cell lines ability to make motor neurons. Mathis then moved to ...