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*  Sonogashira coupling
... yield natural products such as benzylisoquinoline or indole alkaloids An example is the synthesis of the benzylisoquinoline ...
*  Indole alkaloid
Some 200 dimeric indole alkaloids are known with two indole groups. The number of known non-isoprenoid indole alkaloids is ... Indole alkaloids are a class of alkaloids containing a structural moiety of indole; many indole alkaloids also include isoprene ... Pyrolo-indole alkaloids form a relatively small group of tryptamine derivatives. They are produced by methylation of indole ... The amino acid tryptophan is the biochemical precursor of indole alkaloids. The action of some indole alkaloids has been known ...
*  16-Methoxytabersonine
... is a terpene indole alkaloid produced by the medicinal plant Catharanthus roseus. 16-methoxytabersonine ...
*  Purple urine bag syndrome
Indole is absorbed into the blood by the intestine and passes to the liver. There, indole is converted to indoxyl sulfate. ... Tryptophan in the diet is metabolized by bacteria in the gastrointestinal tract to produce indole. ...
*  Tryptophan synthase
Indole-3-glycerol binding site: See image 1. Indole and serine binding site: See image 1. Hydrophobic channel: The α and β ... The α subunits catalyze the reversible formation of indole and glyceraldehyde-3-phosphate (G3P) from indole-3-glycerol ... Tryptophan synthetase is also known to accept indole analogues, e.g., fluorinated or methylated indoles, as substrates, ... If the channel did not exist, the indole formed at an α active site would quickly diffuse away and be lost to the cell as it is ...
*  Indole
Bartoli indole synthesis Bischler-Möhlau indole synthesis Fukuyama indole synthesis Gassman indole synthesis Hemetsberger ... The Leimgruber-Batcho indole synthesis is an efficient method of synthesizing indole and substituted indoles.[citation needed] ... Although the synthesis of indole itself is problematic using the Fischer indole synthesis, it is often used to generate indoles ... indole synthesis Larock indole synthesis Madelung synthesis Nenitzescu indole synthesis Reissert indole synthesis Baeyer- ...
*  Indole test
This is due to the presence of skatole, also known as methyl indole or methylated indole, another possible product of ... The indole test is a biochemical test performed on bacterial species to determine the ability of the organism to convert ... Example of typical indole reactions Angen, O.; Mutters, R.; Caugant, D. A.; Olsen, J. E.; Bisgaard, M. (1999). "Taxonomic ... Like many biochemical tests on bacteria, results of an indole test are indicated by a change in color following a reaction with ...
*  Bartoli indole synthesis
The Leimgruber-Batcho indole synthesis gives similar flexibility and regiospecificity to indole derivatives. One advantage of ... which is difficult to do with the Leimgruber-Batcho indole synthesis. The reaction mechanism of the Bartoli indole synthesis is ... to give a dimagnesium indole salt (12). Reaction workup eliminates water and gives the final desired indole (13). Therefore, ... The Bartoli indole synthesis (also called the Bartoli reaction) is the chemical reaction of ortho-substituted nitroarenes with ...
*  Gassman indole synthesis
The Gassman indole synthesis is a series of chemical reactions used to synthesize substituted indoles by addition of an aniline ... Gassman, P. G.; van Bergen, T. J.; Gilbert, D. P.; Cue, Jr., B. W. (1974). "General method for the synthesis of indoles". J. Am ... Synthesis of indoles, oxindoles, and alkylated aromatic amines bearing cation stabilizing substituents". J. Am. Chem. Soc. 96 ( ... The 3-position thiomethyl group is often removed using Raney nickel to give the 3-H-indole. The reaction mechanism of the ...
*  Indole-3-carboxaldehyde
... (I3A), also known as indole-3-aldehyde and 3-formylindole, is a metabolite of dietary L-tryptophan ... indole-3-propionic acid". J. Biol. Chem. 274 (31): 21937-21942. doi:10.1074/jbc.274.31.21937. PMID 10419516. [Indole-3- ... Molecular mechanisms of action of indole and its metabolites on host physiology and disease "Indole-3-carboxaldehyde". PubChem ... Indole-3-propionate (IPA), a deamination product of tryptophan formed by symbiotic bacteria in the gastrointestinal tract of ...
*  Reissert indole synthesis
The Reissert indole synthesis is a series of chemical reactions designed to synthesize indole or substituted-indoles (4 and 5) ... V. The Structure of Certain Indole Derivatives Related to Gliotoxin1,2". J. Am. Chem. Soc. 67 (3): 423. doi:10.1021/ja01219a023 ... The reductive cyclization of 3 with zinc in acetic acid gives indole-2-carboxylic acid 4. If desired, 4 can be decarboxylated ... with heat to give indole 5. Reissert, A. (1897). "Einwirkung von Oxalester und Natriumäthylat auf Nitrotoluole. Synthese ...
*  Fukuyama indole synthesis
3-disubstituted indoles. A practical one-pot reaction that can be useful for the creation of disubstituted indoles. Most ... the application of the Fukuyama Indole synthesis to create a disubstituted indole. In addition, the fukuyama reaction plays a ... The Fukuyama Indole synthesis can generate a range of different substituents at the 2,3 position that were previously ... The Fukuyama indole synthesis is a versatile tin mediated chemical reaction that results in the formation of 2, ...
*  Nenitzescu indole synthesis
Other solid-phase indole syntheses were also reported, some of which use different scaffolds and metal catalysts to drive the ... There are also a variety of other reactions that result in the same indole skeleton. In a review article, Taber et al. ... The Nenitzescu indole synthesis is a chemical reaction that forms 5-hydroxyindole derivatives from benzoquinone and β- ... Huang, Yun-Sheng; Zhang, W.; Zhang, X.; Wang, J. (2010). "Manufacturing synthesis of 5-hydroxy-2-methyl-1H-indole". Research on ...
*  Fischer indole synthesis
Bartoli indole synthesis Japp-Klingemann indole synthesis Leimgruber-Batcho indole synthesis Larock indole synthesis Madelung ... The Fischer indole synthesis is a chemical reaction that produces the aromatic heterocycle indole from a (substituted) ... Wagaw, S.; Yang, B. H.; Buchwald, S. L. (1998). "A Palladium-Catalyzed Strategy for the Preparation of Indoles: A Novel Entry ... Via a palladium-catalyzed reaction, the Fischer indole synthesis can be effected by cross-coupling aryl bromides and hydrazones ...
*  Hemetsberger indole synthesis
The Hemetsberger indole synthesis (also called the Hemetsberger-Knittel synthesis) is a chemical reaction that thermally ... Gribble, G. W. (2000). "Recent developments in indole ring synthesis-methodology and applications". J. Chem. Soc., Perkin Trans ... decomposes a 3-aryl-2-azido-propenoic ester into an indole-2-carboxylic ester. Yields are typically above 70%. However, this is ...
*  Indole-3-acetaldehyde
... belongs to the class of organic compounds known as indoles. These are compounds containing an indole ... Indole-3-acetaldehyde is a substrate for retina-specific copper amine oxidase, aldehyde dehydrogenase X (mitochondrial), amine ... Nutaratat P, Srisuk N, Arunrattiyakorn P, Limtong S (2016). "Indole-3-acetic acid biosynthetic pathways in the basidiomycetous ...
*  Indole-3-carbinol
... indole-3-carbinol) found in human diet was claimed by Dashwood, et al., in 1989. Indole-3-carbinol induces a G1 growth arrest ... was downregulated by Indole-3-carinol to induce apoptosis. Kundu A et al demonstrated that the anticancer property of Indole-3- ... a fact that can be used to design clinical trial to treat human patients with Indole-3-carbinol in future. Indole-3-carbinol ... to determine if supplemental indole-3-carbinol has health benefits. Investigation of mechanisms by which consumption of indole- ...
*  Indole-2-monooxygenase
... (EC 1.14.13.137, BX2 (gene), CYP71C4 (gene)) is an enzyme with systematic name indole,NAD(P)H:oxygen ... Indole-2-monooxygenase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular Biology ... H2O Indole-2-monooxygenase is involved in the biosynthesis of protective and allelophatic benzoxazinoids in some plants. Frey, ... oxidoreductase (2-hydroxylating). This enzyme catalyses the following chemical reaction indole + NAD(P)H + H+ + O2 ⇌ {\ ...
*  Baeyer-Emmerling indole synthesis
The Baeyer-Emmerling indole synthesis is a method for synthesizing indole from a (substituted) ortho-nitrocinnamic acid and ... Decarboxylation gives indole. Baeyer-Drewson indigo synthesis Bayer, A.; Emmerling, A. (1869). "Synthese des indoles" [ ... Synthesis of indoles]. Berichte der deutschen chemischen Gesellschaft. 2 (1): 679-682. doi:10.1002/cber.186900201268. Baeyer 5 ...
*  Indole-3-acetaldehyde oxidase
In enzymology, an indole-3-acetaldehyde oxidase (EC 1.2.3.7) is an enzyme that catalyzes the chemical reaction (indol-3-yl) ... indol-3-yl)acetaldehyde, H2O, and O2, whereas its two products are (indol-3-yl)acetate and H2O2. This enzyme belongs to the ... Koshiba T, Matsuyama H (1993). "An in Vitro System of Indole-3-Acetic Acid Formation from Tryptophan in Maize (Zea mays) ... The systematic name of this enzyme class is (indol-3-yl)acetaldehyde:oxygen oxidoreductase. Other names in common use include ...
*  Indole-3-acetic acid
Plants mainly produce IAA from tryptophan through indole-3-pyruvic acid. IAA is also produced from tryptophan through indole-3- ... Indole-3-acetic acid (IAA, 3-IAA) is the most common, naturally occurring, plant hormone of the auxin class. It is the best ... Fu SF1 Wei JY, Chen HW, Liu YY, Lu HY, Chou JY (Aug 2015). "Indole-3-acetic acid: A widespread physiological code in ... "Indole-3-Acetic Acid: Material Safety Data Sheet." November 2008. Furukawa, Satoshi; Usuda, Koji; Abe, Masayoshi; Ogawa, Izumi ...
*  Indole-3-butyric acid
... (1H-Indole-3-butanoic acid, IBA) is a white to light-yellow crystalline solid, with the molecular formula ... 180 (1). CS1 maint: Multiple names: authors list (link) Ludwig-Müller, J. (2000). "Indole-3-butyric acid in plant growth and ... Ludwig-Müller, J. (2000). "Indole-3-butyric acid in plant growth and development". Plant Growth Regulation. 32 (2-3). William G ... "Identification and characterization of Arabidopsis indole-3-butyric acid response mutants defective in novel peroxisomal ...
*  Bischler-Möhlau indole synthesis
The Bischler-Möhlau indole synthesis is a chemical reaction that forms a 2-aryl-indole from an α-bromo-acetophenone and excess ... which quickly aromatizes and tautomerizes to give the desired indole 7. Fischer indole synthesis Bischler-Napieralski reaction ... Pchalek, K.; Jones, A. W.; Wekking, M. M. T.; Black, D. S. C. (2005). "Synthesis of activated 3-substituted indoles: An ... Sridharan, V.; Perumal, S.; Avendaño, C.; Menéndez, J. C. (2006). "Microwave-Assisted, Solvent-Free Bischler Indole Synthesis ...
*  6-(2-Aminopropyl)indole
... (6-API, 6-IT) is an indole derivative which was first identified being sold on the designer drug market ... "The effects of an indole derivative 6-(2′-Aminopropyl indole) on the general and coronary haemodynamics of the intact dog". ... This is the 5-isomer, 5-(2-aminopropyl)indole or 5-IT"[1]. Studies in dogs have also shown the drug to increase hemoglobin ...
*  Indole-3-pyruvate monooxygenase
... indol-3-yl)pyruvate + NADPH + H+ + O2 ⇌ {\displaystyle \rightleftharpoons } (indol-3-yl)acetate + NADP+ + H2O + CO2 Indole-3- ... Indole-3-pyruvate monooxygenase (EC 1.14.13.168, YUC2 (gene), spi1 (gene)) is an enzyme with systematic name indole-3-pyruvate, ... Indole-3-pyruvate monooxygenase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular ... Zhao, Y. (2012). "Auxin biosynthesis: a simple two-step pathway converts tryptophan to indole-3-acetic acid in plants". Mol. ...