C1-set domains are found almost exclusively in molecules involved in the immune system, such as in immunoglobulin light and ...
CD2 CD4 VCAM1 Smith DK, Xue H (1997). "Sequence profiles of immunoglobulin and immunoglobulin-like domains". J. Mol. Biol. 274 ... Immunoglobulin-like domains that are related in both sequence and structure can be found in several diverse protein families. ... CD4 is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same ... The basic structure of immunoglobulin (Ig) molecules is a tetramer of two light chains and two heavy chains linked by ...
... (TIM) proteins are a family of cell surface immunomodulatory proteins. TIM1 Kane ...
Members of the IgSF family include the human killer cell immunoglobulin-like receptor (KIR) and the Immunoglobulin-like ... includes immunoglobulin-like transcripts (ILT, also known as leukocyte immunoglobulin-like receptors (LIRs)), leukocyte- ... Human killer cell immunoglobulin-like receptors recognize the α1 and α2 domains of class I human leukocyte antigens (HLA-A, -B ... Killer-cell immunoglobulin-like receptors (KIRs), are a family of type I transmembrane glycoproteins expressed on the plasma ...
... is a immunoglobulin gene with symbol IGHA1. It encodes a constant (C) segment of ... Immunoglobulin A is an antibody that plays a critical role in immune function in the mucous membranes. IgA shows the same ... "Entrez Gene: IGHA1 immunoglobulin heavy constant alpha 1". Kratzin, H.; Altevogt, P.; Ruban, E.; Kortt, A.; Staroscik, K.; ... "IGHA1 immunoglobulin heavy constant alpha 1 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2016-10-16 ...
Immunodeficiency with hyper-immunoglobulin M Immunoglobulin M List of cutaneous conditions Rapini, Ronald P.; Bolognia, Jean L ... Isolated primary immunoglobulin M deficiency is a poorly defined dysgammaglobulinemia characterized by decreased levels of IgM ... Geier, Christoph (18 December 2018). "Hypomorphic Mutations in the BCR Signalosome Lead to Selective Immunoglobulin M ... while dysfunctioning of IgM synthesis is expected to occur together with abnormalities in other immunoglobulins. ...
KIR2DL3, Killer cell immunoglobulin-like receptor 2DL3 is a transmembrane glycoprotein expressed by the natural killer cells ... "KIR2DL3 - Killer cell immunoglobulin-like receptor 2DL3 precursor - Homo sapiens (Human) - KIR2DL3 gene & protein". www.uniprot ... including killer cell immunoglobulin-like receptors (KIR) that predominantly recognize antigens of class I human leukocyte ... "NK Cells Expressing the Inhibitory Killer Immunoglobulin-Like Receptors (iKIR) KIR2DL1, KIR2DL3 and KIR3DL1 Are Less Likely to ...
Antibody (or immunoglobulin) structure is made up of two heavy-chains and two light-chains. These chains are held together by ... During the development of B cells, the immunoglobulin gene undergoes sequences of rearrangements that lead to formation of the ... 1979). "Cloned pairs of variable region genes for immunoglobulin heavy-chains isolated from a clone library of the entire mouse ... For example, interleukin-4 induces the rearrangements of heavy chain immunoglobulin genes. That is IL- 4 induces the switching ...
... is a protein that in humans is encoded by the LILRP2 gene. ENSG00000273922 ... "Entrez Gene: Leukocyte immunoglobulin-like receptor pseudogene 2". Retrieved 2016-09-02. v t e (Articles with short description ...
complement system immunoglobulin Helmy K, Katschke K, Gorgani N, Kljavin N, Elliott J, Diehl L, Scales S, Ghilardi N, van ... Complement receptor of the immunoglobulin family is a protein expressed in Kupffer cells. It is a critical receptor for the ...
... is a protein that in humans is encoded by the VSIG4 gene. This gene encodes a v- ... "Entrez Gene: V-set and immunoglobulin domain containing 4". Retrieved 2016-06-13. Helmy KY, Katschke KJ, Gorgani NN, Kljavin NM ... set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. ...
... and immunoglobulins. Blood products may also be called blood-based products to differ from blood substitutes, which generally ...
Heavy chains only (also known as "heavy chain disease"); Whole immunoglobulins. If immunoglobulins tend to precipitate within ... The γ band is where the immunoglobulins appear, which is why they are also known as gammaglobulins. The majority of ... Note that while most heavy chains or whole immunoglobulins remain within blood vessels, light chains frequently escape and are ... usually whole immunoglobulins) to form polymers by aggregating with each other; this takes the name of macroglobulinemia and ...
PSG is a member of the immunoglobulin (Ig) superfamily and contains four immunoglobulin domains. The complete isolation of ... CEAs are immunoglobulins. Within humans there are total of 11 PSG genes located on the 19th chromosome; there are 17 genes ... Khan WN, Teglund S, Bremer K, Hammarström S (1992). "The pregnancy-specific glycoprotein family of the immunoglobulin ... a new subfamily of the immunoglobulin gene superfamily". Biochemistry. 29 (11): 2845-52. doi:10.1021/bi00463a030. PMID 2346748 ...
Each immunoglobulin domain has a similar structure, characteristic of all the members of the immunoglobulin superfamily: it is ... Somatic recombination of immunoglobulins, also known as V(D)J recombination, involves the generation of a unique immunoglobulin ... The membrane-bound form of an antibody may be called a surface immunoglobulin (sIg) or a membrane immunoglobulin (mIg). It is ... Antibodies are glycoproteins belonging to the immunoglobulin superfamily. The terms antibody and immunoglobulin are often used ...
Secretion of immunoglobulins. IgA from plasma cells in the mucosa are absorbed through receptor-mediated endocytosis on the ...
Hepatitis B immunoglobulin (HBIG) is a human immunoglobulin that is used to prevent the development of hepatitis B and is used ... Allergy to human immunoglobulin is a contraindication. HIV has never been transmitted by HBIG. As with all blood-derived ... "Hepatitis B immunoglobulins". Drug Information Portal. U.S. National Library of Medicine. Portal: Medicine (Webarchive template ... It provides a temporarily induced immunity by the transfer of immunoglobulins.[citation needed] HBIG is given by either ...
... immunoglobulin lambda constant 1 (Mcg marker) IGLC2 - immunoglobulin lambda constant 2 (Kern-Oz- marker) IGLC3 - immunoglobulin ... "Entrez Gene: IGL@ immunoglobulin lambda locus". Taussig MJ (1988). "Molecular genetics of immunoglobulins". Immunology. ... immunoglobulin lambda joining n IGLJ1, IGLJ2, IGLJ3, IGLJ6, IGLJ7 IGLV@ - variable group IGLVm-n - immunoglobulin lambda ... or immunoglobulins). Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the ...
Immunoglobulin-like domains: found in proteins of the immunoglobulin superfamily (IgSF). They contain about 70-110 amino acids ... Four concrete examples of widespread protein modules are the following domains: SH2, immunoglobulin, fibronectin type 3 and the ... Barclay AN (August 2003). "Membrane proteins with immunoglobulin-like domains--a master superfamily of interaction molecules". ... Porter RR (May 1973). "Structural studies of immunoglobulins". Science. 180 (4087): 713-6. Bibcode:1973Sci...180..713P. doi: ...
Gottlieb, Paul David (1972). "The variability of immunoglobulins". elibrary.ru: 1. Kobler, John (1977). The Rockefeller ... "The covalent structure of a human gamma G-immunoglobulin. V. Partial amino acid sequence of the light chain". Biochemistry. 7 ( ... "The covalent structure of an entire gammaG immunoglobulin molecule". Proceedings of the National Academy of Sciences of the ... "Variable regions of heavy and light polypeptide chains of the same gammaG-immunoglobulin molecule". Proceedings of the National ...
Immunoglobulins are of unclear benefit. Bronchiolitis typically affects infants and children younger than two years, ... Sanders SL, Agwan S, Hassan M, van Driel ML, Del Mar CB (August 2019). "Immunoglobulin treatment for hospitalised infants and ...
"Entrez Gene: IGJ immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides". Frutiger S, Hughes ... Clem IW, De Boutaud F, Sigel MM (December 1967). "Phylogeny of immunoglobulin structure and function. II. Immunoglobulins of ... Koshland ME (1986). "The coming of age of the immunoglobulin J chain". Annual Review of Immunology. 3: 425-453. doi:10.1146/ ... Moro I, Iwase T, Komiyama K, Moldoveanu Z, Mestecky J (April 1990). "Immunoglobulin A (IgA) polymerization sites in human ...
Weissmann, G.; Brand, A.; Franklin, E.C. (February 1974). "Interaction of immunoglobulins with liposomes". The Journal of ...
Solomon A (1985). "[6] Light chains of human immunoglobulins". Light chains of human immunoglobulins. Methods in Enzymology. ... There is approximately 40% excess immunoglobulin light-chain production over immunoglobulin heavy-chain synthesis. Possibly ... Immunoglobulin light chains that are circulating in serum in a free (unbound) state are called free light chains (FLCs). ... Each immunoglobulin light-chain molecule contains approximately 220 amino acids in a single polypeptide chain that is folded to ...
Gray, O.; McDonnell, G. V.; Forbes, R. B. (2003). "Intravenous immunoglobulins for multiple sclerosis". The Cochrane Database ...
"Structure and function of immunoglobulins". Journal of Allergy and Clinical Immunology. 2010 Primer on Allergic and Immunologic ...
"Intravenous Immunoglobulin". Intravenous Immunoglobulin. Medscape. Perumbeti, Ajay (2018-08-06). "Hematopoietic Stem Cell ...
The structure of immunoglobulin polypeptide chain is dictated and controlled by number of genes encoded in the germ line. ... Immunoglobulin+allotypes at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Genetics, Transplantation ... However, it is important to mention that not all variations in immunoglobulin amino acid sequence pose as a determinant ... Mage R, Lieberman R, Potter M, Terry WD (January 1973). "Immunoglobulin Allotypes". The Antigens. Academic Press. pp. 299-376. ...
In the US it is recommended people receive one dose of human rabies immunoglobulin (HRIG) and four doses of rabies vaccine over ... In people who have been exposed to rabies, the rabies vaccine and sometimes rabies immunoglobulin are effective in preventing ... "Rabies immunoglobulin". Milton Keynes Formulary Formulary. "Rabies - Vaccination". National Health Services (NHS). UK. 23 ... People who have previously been vaccinated against rabies do not need to receive the immunoglobulin-only the postexposure ...
"The generation of diversity in immunoglobulins". Immunobiology: The Immune System in Health and Disease (5th ed.). New York: ...