Immunoglobulin therapy
... that they do not with intravenous immunoglobulin (IVIg). Although intravenous was the preferred route for immunoglobulin ... human normal immunoglobulin), and Flebogamma DIF (human normal immunoglobulin). In the EU human normal immunoglobulin (SCIg) ( ... August 2019). "Intravenous immunoglobulin induces IL-4 in human basophils by signaling through surface-bound IgE" (PDF). The ... "Access to Intravenous Immunoglobulin (IVIg)". National Blood Authority. Archived from the original on 2 April 2020. Retrieved ...
Multiple sclerosis research
Gray, O.; McDonnell, G. V.; Forbes, R. B. (2003). "Intravenous immunoglobulins for multiple sclerosis". The Cochrane Database ... Zipoli V, Portaccio E, Hakiki B, Siracusa G, Sorbi S, Pia Amato M (2007). "Intravenous mitoxantrone and cyclophosphamide as ... research is now being carried out to understand and implement what intravenous contrast agents would be reserved for patients ...
Reticular dysgenesis
"Intravenous Immunoglobulin". Intravenous Immunoglobulin. Medscape. Perumbeti, Ajay (2018-08-06). "Hematopoietic Stem Cell ... Hematopoietic stem cell transplantation (HSCT) involves intravenous infusion of stem cells to those who have either a damaged ...
Pemphigoid
Czernik A, Toosi S, Bystryn JC, Grando SA (February 2012). "Intravenous immunoglobulin in the treatment of autoimmune bullous ... Anti-inflammatory drugs 3. Biologic therapy i. Intravenous immunoglobulin ii. Rituximab Among all, topical or systemic ... For refractory disease, biologic therapies such as intravenous immunoglobulin and Rituximab should be considered. [1,19,20] ... Other classes of immunoglobulins such as IgM and IgA are present in approximately 20% of cases and usually are less intense. In ...
Opsoclonus myoclonus syndrome
Intravenous Immunoglobulins (IVIg) are often used with varying results. Several other immunosuppressive drugs, such as ...
Degos disease
"Inefficacy of intravenous immunoglobulins and infliximab in Degos' disease". Acta Clin Belg. 63 (2): 99-102. doi:10.1179/acb. ...
Toxic epidermal necrolysis
Initial interest in Intravenous immunoglobulin (IVIG) came from research showing that IVIG could inhibit Fas-FasL mediated ... Antibiotics, intravenous immunoglobulins, and corticosteroids may also be used. Treatments do not typically change the course ... high mag Staphylococcal scalded skin syndrome Drug-induced linear immunoglobulin A dermatosis Acute graft versus host disease ...
Hemolytic disease of the newborn (anti-Kell)
IVIG - IVIG stands for Intravenous Immunoglobulin. It is used in cases of previous loss, high maternal titers, known aggressive ... Gottstein, R (2003). "Systematic review of intravenous immunoglobulin in haemolytic disease of the newborn". Archives of ... Onesimo, Roberta; Rizzo, Daniela; Ruggiero, Antonio; Valentini, Piero (2010). "Intravenous Immunoglobulin therapy for anti-E ... alloimmunization treated by intensive plasma exchange and high-dose intravenous immunoglobulin". Transfusion and Apheresis ...
Evans syndrome
Initial treatment is with glucocorticoid corticosteroids or intravenous immunoglobulin, a treatment that is also used in ITP ... Mehta JB, Singhal SB, Mehta BC (1992). "Intravenous immunoglobulin therapy of idiopathic thrombocytopenia". The Journal of the ... Nuss R, Wang W (1987). "Intravenous gamma globulin for thrombocytopenia in children with Evans syndrome". The American Journal ...
Henoch-Schönlein purpura
Intravenous immunoglobulin (IVIG) is occasionally used. There is no good evidence that treating children who have HSP with ... Henoch-Schönlein purpura is a small-vessel vasculitis in which complexes of immunoglobulin A (IgA) and complement component 3 ( ... "Genetics of immunoglobulin-A vasculitis (Henoch-Schönlein purpura): An updated review". Autoimmunity Reviews. 17 (3): 301-315. ... and is characterized by deposition of immune complexes containing the antibody immunoglobulin A (IgA); the exact cause for this ...
Guillain-Barré syndrome
Intravenous immunoglobulins were introduced in 1988, and studies in the early 1990s demonstrated that they were no less ... Plasmapheresis and intravenous immunoglobulins (IVIG) are the two main immunotherapy treatments for GBS. Plasmapheresis ... In those who have received intravenous immunoglobulins, a smaller increase in IgG in the blood two weeks after administration ... Hughes RA, Swan AV, van Doorn PA (September 2014). "Intravenous immunoglobulin for Guillain-Barré syndrome". The Cochrane ...
Neonatal Fc receptor
One such therapy is the infusion of intravenous immunoglobulin (IVIg) to saturate FcRn's IgG recycling capacity and ... Hansen RJ, Balthasar JP (June 2003). "Pharmacokinetic/pharmacodynamic modeling of the effects of intravenous immunoglobulin on ... Nimmerjahn F, Ravetch JV (2008-01-01). "Anti-inflammatory actions of intravenous immunoglobulin". Annual Review of Immunology. ... Vaccaro C, Zhou J, Ober RJ, Ward ES (October 2005). "Engineering the Fc region of immunoglobulin G to modulate in vivo antibody ...
Dermatomyositis
... intravenous immunoglobulin has had the best outcomes. Before the advent of modern treatments such as prednisone, intravenous ... Intravenous immunoglobulin may also improve outcomes. Most people improve with treatment and in some, the condition resolves ... Periodic treatment using intravenous immunoglobulin can also improve recovery. Other immunosuppressive agents used to treat the ... intravenous immunoglobulin, methotrexate, azathioprine, and mycophenolate mofetil. None appears to be very effective; among ...
Hemolytic disease of the newborn (anti-Rhc)
IVIG - IVIG stands for Intravenous Immunoglobulin. It is used in cases of previous loss, high maternal titers, known aggressive ... Gottstein, R; Cooke, R. W. (2003). "Systematic review of intravenous immunoglobulin in haemolytic disease of the newborn". ... Onesimo, Roberta; Rizzo, Daniela; Ruggiero, Antonio; Valentini, Piero (2010). "Intravenous Immunoglobulin therapy for anti-E ... alloimmunization treated by intensive plasma exchange and high-dose intravenous immunoglobulin". Transfusion and Apheresis ...
Autoimmune retinopathy
Methods of treatment include intravenous immunoglobulin (IVIG), plasmapheresis, and corticosteroids. Immunoglobulin samples are ... Pyne, D.; Ehrenstein, M.; Morris, V. (2002-04-01). "The therapeutic uses of intravenous immunoglobulins in autoimmune rheumatic ... obtained from a large pool of healthy, matched donors (10000 - 20000). The immunoglobulin mixture is then administered through ...
Hemophagocytic lymphohistiocytosis
Intravenous immunoglobulin is also used. Methotrexate and vincristine have also been used. Other medications include cytokine ... IV immunoglobulin only). However, long-term remission without the use of cytotoxic and immune-suppressive therapies is unlikely ...
Audrius V. Plioplys
Plioplys, AV (1998). "Intravenous immunoglobulin treatment of children with autism". J Child Neurol. 13 (2): 79-82. doi:10.1177 ... "Intravenous immunoglobulin treatment of children with autism (Plioplys AV. J Child Neurol. 1998; 13:79-82)", "Pulmonary vest ...
Kimura's disease
Initially treated with corticosteroids, he was given a single dose of intravenous immunoglobulin (IVIG) as a steroid-sparing ... "Treatment of Kimura disease with intravenous immunoglobulin". Pediatrics. 128 (6): e1633-5. doi:10.1542/peds.2010-1623. PMID ... Peripheral blood eosinophilia and elevated serum immunoglobulin E (IgE) levels are constant features of Kimura's disease. ...
Morvan's syndrome
Intravenous immunoglobulin was effective in one case. In one case, the dramatic response to high-dose oral prednisolone ... Yet, in two cases, oligoclonal bands were absent in the CSF and serum, and CSF immunoglobulin profiles were unremarkable. In ... Cerebral spinal fluid (CSF) shows normal protein, glucose, white blood cell, and immunoglobulin G (IgG) levels, but there are ...
Blood transfusion
Intravenous immunoglobulin (IVIG) is treatment of choice. Transfusion-related acute lung injury (TRALI) is a syndrome that is ... For patients who have selective immunoglobulin A deficiency, the reaction is presumed to be caused by IgA antibodies in the ... and immunoglobulins (antibodies). Red cells, plasma and platelets can also be donated individually via a more complex process ... "The history of peripheral intravenous catheters: how little plastic tubes revolutionized medicine" (PDF). Acta ...
Statin-associated autoimmune myopathy
Rituximab or intravenous immunoglobulin are recommended as add-on therapy in such cases. Intravenous immunoglobulin is an ... Suitable candidates for first-line intravenous immunoglobulin include people who have diabetes mellitus or who wish to avoid ...
Fred D. Lublin
July 2008). "Intravenous immunoglobulin in relapsing-remitting multiple sclerosis: a dose-finding trial". Neurology. 71 (4): ...
Acute disseminated encephalomyelitis
... high doses of intravenous immunoglobulin (IVIg), mitoxantrone and cyclophosphamide. These are considered alternative therapies ... "Improvement of atypical acute disseminated encephalomyelitis with steroids and intravenous immunoglobulins". Pediatric ... The widely accepted first-line treatment is high doses of intravenous corticosteroids, such as methylprednisolone or ... April 2007). "Guidelines on the use of intravenous immune globulin for neurologic conditions". Transfusion Medicine Reviews. 21 ...
Hemolytic disease of the newborn
Early pregnancy IVIG - IVIG stands for Intravenous Immunoglobulin. It is used in cases of previous loss, high maternal titers, ... Onesimo R, Rizzo D, Ruggiero A, Valentini P (September 2010). "Intravenous Immunoglobulin therapy for anti-E hemolytic disease ... Gottstein R, Cooke RW (January 2003). "Systematic review of intravenous immunoglobulin in haemolytic disease of the newborn". ... alloimmunization treated by intensive plasma exchange and high-dose intravenous immunoglobulin". Transfusion and Apheresis ...
Hemolytic disease of the newborn (anti-RhE)
Onesimo, R; Rizzo, D; Ruggiero, A; Valentini, P (2010). "Intravenous Immunoglobulin therapy for anti-E hemolytic disease in the ... Gottstein, R (2003). "Systematic review of intravenous immunoglobulin in haemolytic disease of the newborn". Archives of ... IVIG stands for intravenous immunoglobulin. It is used in cases of previous loss, high maternal titers, known aggressive ... alloimmunization treated by intensive plasma exchange and high-dose intravenous immunoglobulin". Transfusion and Apheresis ...
Encephalitis
Intravenous immunoglobulin for Japanese encephalitis appeared to have no benefit when compared with placebo (pretend) treatment ... The effectiveness of intravenous immunoglobulin for the management of childhood encephalitis is unclear. Systematic reviews ... There is the possibility of a benefit of intravenous immunoglobulin for some forms of childhood encephalitis on some indicators ... Iro MA, Martin NG, Absoud M, Pollard AJ (October 2017). "Intravenous immunoglobulin for the treatment of childhood encephalitis ...
Inflammatory myopathy
Cherin P, Pelletier S, Teixeira A, Laforet P, Simon A, Herson S, Eymard B (January 2002). "Intravenous immunoglobulin for ... For patients not responding to this approach there is weak evidence supporting the use of intravenous immunoglobulin, ... Dysphagia (difficulty swallowing) may be improved by intravenous immunoglobulin, though more trials are needed. Non-fatiguing, ... In severe cases of PM and DM with systemic signs, an initial three to five days on intravenous corticosteroid ( ...
Hemolytic jaundice
... intravenous immunoglobulin therapy may be used to treat the condition. Administration of intravenous immunoglobulin can block ... Ergaz Z, Arad I (1993-01-01). "Intravenous immunoglobulin therapy in neonatal immune hemolytic jaundice". Journal of Perinatal ...
Sydenham's chorea
"Successful treatment of Sydenham's chorea with intravenous immunoglobulin". BMJ Case Reports. 2016: bcr2015211673. doi:10.1136/ ... "Neuropsychological manifestations in children with Sydenham's chorea after adjunct intravenous immunoglobulin and standard ... Immunoglobulin has been used in Holland and South Africa. Some improvement can be seen within a few days of IV steroids. In ...
Japanese encephalitis
The effectiveness of intravenous immunoglobulin for the management of encephalitis is unclear due to a lack of evidence. ... Intravenous immunoglobulin for Japanese encephalitis appeared to have no benefit. Japanese encephalitis (JE) is the leading ... Iro, Mildred A.; Martin, Natalie G.; Absoud, Michael; Pollard, Andrew J. (2 October 2017). "Intravenous immunoglobulin for the ...