Beachboard, Dia C.; Horner, Stacy M. (August 2016). "Innate immune evasion strategies of DNA and RNA viruses". Current Opinion ... The human immune system relies on a plethora of cell-cell signaling pathways to transmit information about a cell's health and ... The mammalian immune system has evolved complex methods for addressing and adapting to foreign antigens. At the same time, ... DNA and RNA viruses use complex methods to evade immune cell detection through disruption of the Interferon Signaling Pathway, ...
Foster TJ (December 2005). "Immune evasion by staphylococci". Nat. Rev. Microbiol. 3 (12): 948-58. doi:10.1038/nrmicro1289. ... immune evasion, and virulence". J. Biol. Chem. 279 (52): 54881-86. doi:10.1074/jbc.M411374200. PMID 15501828. Melin M, Jarva H ... The ability of amoebae to distinguish between self and non-self is a pivotal one, and is the root of the immune system of many ... This material is then displayed to other cells of the immune system. Some phagocytes then travel to the body's lymph nodes and ...
Ramanan P, Shabman RS, Brown CS, Amarasinghe GK, Basler CF, Leung DW (September 2011). "Filoviral immune evasion mechanisms". ... Filoviral infection also interferes with proper functioning of the innate immune system. EBOV proteins blunt the human immune ... Following infection, immune cells carry the virus to nearby lymph nodes where further reproduction of the virus takes place. ... By inhibiting these immune responses, EBOV may quickly spread throughout the body. When EVD is suspected, travel, work history ...
An evasion strategy used by several pathogens to avoid the innate immune system is to hide within the cells of their host (also ... Overactive immune responses form the other end of immune dysfunction, particularly the autoimmune diseases. Here, the immune ... Finlay BB, McFadden G (February 2006). "Anti-immunology: evasion of the host immune system by bacterial and viral pathogens". ... The adaptive immune system evolved in early vertebrates and allows for a stronger immune response as well as immunological ...
Blake, N. (2010). "Immune evasion by gammaherpesvirus genome maintenance proteins". Journal of General Virology. 91 (4): 829- ... Stevenson, P. G. (2004). "Immune evasion by gamma-herpesviruses". Current Opinion in Immunology. 16 (4): 456-462. doi:10.1016/j ... Sorel, Océane; Dewals, Benjamin G. (2019). "The Critical Role of Genome Maintenance Proteins in Immune Evasion During ... yet at the same time must also be capable of avoiding elimination by the immune surveillance system especially must avoid being ...
Kennedy A. "Immune Evasion by bacteria". Crohnie. Archived from the original on 10 October 2006. Retrieved 25 October 2006. ... Finlay BB, McFadden G (February 2006). "Anti-immunology: evasion of the host immune system by bacterial and viral pathogens". ... The innate immune system is an alternate defense strategy and is the dominant immune system response found in plants, fungi, ... The innate, or nonspecific, immune system is one of the two main immunity strategies (the other being the adaptive immune ...
"Detailseite: Toll-like Rezeptoren: Ziele der herpesviralen Immun-Evasion? / Goals of Herpes Virus Immune Evasion?". Herpesviren ... Since 2010 she has been co-leader of the DFG project on Modulation of the Immune Response through the Gammaherpesvirinae-linked ... "Viral Immune Modulation .... Prof Dr Melanie Brinkmann". Helmholtz-Zentrum für Infektionsforschung GmbH, Braunschweig. ... the project had as its objective the investigation of Herpesvirales immune escape. ...
Pathogenesis and Immune Evasion". Journal of Oncology. 2010: 1-14. doi:10.1155/2010/516047. PMC 2952908. PMID 20953370. Fujita ... Malaria also promotes B-cell proliferation by altering the regular immune response. The immune system targets antigens (e.g., ... Downregulation of antigens targeted by the immune system leads to the development of persistent B cells. These B cells can then ... thus evades an immune response. EBNA 1 can be presented via HLA class II molecules, however HLA Class II pathway is unable to ...
Liang, C; Lee, JS; Jung, JU (2008). "Immune evasion in KSHV-associated oncogenesis". Semin Cancer Biol. 18 (6): 423-436. doi: ... His research addresses several key biological features of virus-host interactions, with a focus on host immune responses to ...
Fang P, Yu H, Li M, He R, Zhu Y, Liu S (September 2019). "Rubicon: a facilitator of viral immune evasion". Cellular & Molecular ... Rubicon has been shown to suppress the innate immune response and in some cases exacerbate viral replication. Rubicon ... Rubicon has also been shown to negatively regulate the innate immune response through direct interaction with multiple ...
Zandi, Milad; Shafaati, Maryam; Hosseini, Fatemeh (2023-02-01). "Mechanisms of immune evasion of monkeypox virus". Frontiers in ... Furthermore, the large size makes it harder for the virus to quickly replicate and evade immune response. To evade host immune ... Pox viruses have mechanisms to evade the hosts' innate and adaptive immune systems. Viral proteins, expressed by infected cells ... and preventing activation of proteins within the host's immune system, and preventing infected cells from dying to enable them ...
"Temperature triggers immune evasion by Neisseria meningitidis". Nature. 502 (7470): 237-240. Bibcode:2013Natur.502..237L. doi: ... an RNA thermometer that modulates immune evasion by Neisseria meningitidis". Nucleic Acids Research. 44 (19): 9426-9437. doi: ... which is essential for bacterial resistance against immune killing (lst). The very different nucleotide sequence and predicted ...
ISBN 978-1-118-65062-2. Thompson, Stuart A. (December 2002). "Campylobacter Surface-Layers (S-Layers) and Immune Evasion". ... C. fetus may evade complete detection and eradication by the immune system as chronic and relapse cases have been noted. The ... Ewes can often mount sufficient immune responses following infection, therefore subsequent lambing seasons are not as severely ... enzyme linked immune sorbent assays (ELISA), and vaginal mucus agglutination test (VMAT). Diagnosis depends on isolation of the ...
... , immune escape, immune evasion or escape mutation occurs when the immune system of a host, especially of a ... Viral strategies for immune response evasion Allen, Clint; Clavijo, Paul; Waes, Carter; Chen, Zhong (2015). "Anti-Tumor ... Trypanosomes are also able to achieve evasion through the mediation of the host's immune response. Through the conversion of ... Many head and neck cancers are able to escape immune responses in a variety of ways. One such example is through the production ...
Thompson SA (December 2002). "Campylobacter surface-layers (S-layers) and immune evasion". Annals of Periodontology. 7 (1): 43- ... Most of the bacteria in and on the body are harmless or rendered so by the protective effects of the immune system, and many ... These structures can protect cells from engulfment by eukaryotic cells such as macrophages (part of the human immune system). ...
Gretchen Vogel (22 May 2022). "New versions of Omicron are masters of immune evasion". Science. "BioNTech says it could tweak ... Mohsin M, Mahmud S (May 2022). "Omicron SARS-CoV-2 variant of concern: A review on its transmissibility, immune evasion, ... 2021). "Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement". bioRxiv 10.1101/2021.12.28.474380. ... February 2022 data suggested Omicron caused significant humoral immune evasion, while neutralizing antibodies targeting the ...
ISBN 978-981-10-1711-7. Hazra, Bibhabasu; Chakraborty, Surajit; Basu, Anirban (2017). "miR-301a mediated immune evasion by ... "The host microRNA miR-301a blocks the IRF1-mediated neuronal innate immune response to Japanese encephalitis virus infection". ...
Flynn JL, Chan J (August 2003). "Immune evasion by Mycobacterium tuberculosis: living with the enemy". Current Opinion in ... Granulomas play dual roles during infection: they regulate the immune response and minimize tissue damage, but also can aid in ... Granulomas, organized aggregates of immune cells, are a hallmark feature of tuberculosis infection. ... and better immune response to the COVID-19. The DNA Vaccine, according to an article of the Journal of Preventive, Diagnostic ...
"Complex pattern of immune evasion in MSI colorectal cancer". OncoImmunology. 7 (7): e1445453. doi:10.1080/2162402X.2018.1445453 ... The Immune Biology of Microsatellite-Unstable Cancer. Trends Cancer. 2(3), pp. 121-133. "Universitätsklinikum Heidelberg: ... demonstrated that MSI cancers in particular patients affected by the Lynch syndrome predominantly develop via immune evasion ... He was the first to show that patients develop specific immune responses to altered proteins encoded by the genes affected by ...
Immune system is the key player in fighting cancer. As described above in mechanisms of tumor evasion, the tumor cells are ... December 2015). "Immune evasion in cancer: Mechanistic basis and therapeutic strategies". Seminars in Cancer Biology. A broad- ... Tumors may express tumor antigens that are recognized by the immune system and may induce an immune response. These tumor ... Both adaptive and innate immune system participate in immunoediting. In the elimination phase, the immune response leads to ...
Rudenko G (2011-10-24). "African trypanosomes: the genome and adaptations for immune evasion". Essays in Biochemistry. 51: 47- ... The properties of the VSG coat that enable immune evasion are: Shielding - the dense nature of the VSG coat (VSG proteins pack ... vastly increasing the trypanosome's capacity for immune evasion and posing a major problem for vaccine development. VSG genes ... A diverse range of coats expressed by the trypanosome population means that the immune system is always one step behind: it ...
One way this is possible is through immune evasion. Herpesviruses have many different ways of evading the immune system. One ... These two events allow for immune evasion by suppressing the cell-mediated immune response and natural killer cell response, ... Lin A, Xu H, Yan W (April 2007). "Modulation of HLA expression in human cytomegalovirus immune evasion". Cellular & Molecular ... Another one of the many ways in which herpes viruses evade the immune system is by down regulation of MHC I and MHC II. This is ...
"Cap binding and immune evasion revealed by Lassa nucleoprotein structure". Nature. 468 (7325): 779-783. Bibcode:2010Natur.468.. ...
"Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT". Cell. 165 (1): 45-60. doi:10.1016/j.cell.2016.02. ... Wnt is down-regulated during the dormancy stage by autocrine DKK1 to avoid immune surveillance, as well as during the ...
"Memory in Fungal Pathogens Promotes Immune Evasion, Colonisation, and Infection". Trends in Microbiology. 27 (3): 219-230. doi: ...
Coronavirus nsp12 also plays a role in host immune evasion; research has demonstrated that nsp12 inhibits the nuclear ...
This immune evasion strategy prevents the immune system from developing immunological memory against the pathogen. Broadly ... Guha, Debjani; Ayyavoo, Velpandi (2013). "Innate Immune Evasion Strategies by Human Immunodeficiency Virus Type 1". ISRN AIDS. ... Here, the immune system uses other functions of antibodies, like opsonisation and complement activation, to kill the bacteria. ... A strong diversity in the antibody repertoire allows the immune system to recognize a plethora of pathogens which can come in ...
"Community-associated methicillin-resistant Staphylococcus aureus immune evasion and virulence". Journal of Molecular Medicine. ... Rapid pathogen-specific recruitment of immune effector cells in the skin by secreted toxins. Nat Microbiol. 2022 Jan;7(1):62-72 ...
October 2019). "A Phage Protein Aids Bacterial Symbionts in Eukaryote Immune Evasion". Cell Host & Microbe. 26 (4): 542-550.e5 ... Popescu M, Van Belleghem JD, Khosravi A, Bollyky PL (September 2021). "Bacteriophages and the Immune System". Annual Review of ... Phages are known to interact with the immune system both indirectly via bacterial expression of phage-encoded proteins and ... which are important virulence factors protecting bacterial cells against both immune host defenses and antibiotics. To enter a ...
"Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT". Cell. 165 (1): 45-60. doi:10.1016/j.cell.2016.02. ... and the interplay of metastatic stem cells with the innate immune system. On January 13, 2020, a study by Massagué-led Sloan ...