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*  Xanthoma
The presence of palmar xanthomata, like the presence of tendinous xanthomata, is indicative of hypercholesterolaemia. ... Also associated with familial hypercholesterolemia (FH). Eruptive xanthoma (ILDS E78.220) is clinically characterized by small ... Tendon Xanthoma in Familial Hypercholesterolemia". New England Journal of Medicine. 338 (22): 1591-1591. doi:10.1056/ ...
*  Cholesterol absorption inhibitor
Managing cholesterol at the site of absorption is an increasingly popular strategy in the treatment of hypercholesterolemia[ ... in patients with primary hypercholesterolemia". Am. J. Cardiol. 90 (10): 1092-7. doi:10.1016/S0002-9149(02)02798-4. PMID ...
*  Hypertriglyceridemia
Elevated levels of triglycerides are associated with atherosclerosis, even in the absence of hypercholesterolemia (high ...
*  Lipid profile
This screening can be valuable to detect genetic diseases such as familial hypercholesterolemia that can be lethal if not ...
*  Hypercholesterolemia
Some types of hypercholesterolemia lead to specific physical findings. For example, familial hypercholesterolemia (Type IIa ... If the hypercholesterolemia is hereditary (familial hypercholesterolemia), more often a family history of premature, earlier ... Hence, hypothyroidism (lack of thyroid hormone) causes hypercholesterolemia. Hypercholesterolemia may be a side effect of a ... Genetic screening is now advised if a form of familial hypercholesterolemia is suspected. Classically, hypercholesterolemia was ...
*  Familial hypercholesterolemia
Hypercholesterolemia. (June 2011). "Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult ... Familial hypercholesterolaemia - report of a WHO consultation - (1998) on the diagnosis and treatment of FH Database of all ... Familial hypercholesterolemia (FH) is a genetic disorder characterized by high cholesterol levels, specifically very high ... 2006). "Diagnosing familial hypercholesterolaemia: the relevance of genetic testing". Eur. Heart J. 27 (18): 2240-6. doi: ...
*  DMOZ - Health: Conditions and Diseases: Nutritional and Metabolic Disorders: Cholesterol and Other Fats: Hypercholesterolemia
"Health ... Hypercholesterolemia" search on: AOL - Ask - Bing - DuckDuckGo - Gigablast - Google - ixquick - Yahoo - Yandex - ... Health Conditions and Diseases Nutritional and Metabolic Disorders Cholesterol and Other Fats Hypercholesterolemia 12 ...
*  Essentiale
... hypercholesterolemia, hypertriglyceridemia; Diseases of the cardiovascular system: coronary heart disease, stable stenocardia, ...
*  List of OMIM disorder codes
APOB Hypercholesterolemia, familial; 143890; LDLR Hypercholesterolemia, familial, 3; 603776; PCSK9 Hypercholesterolemia, ... TJP2 Hypercholesterolemia, due to ligand-defective apo B; 144010; ... familial, autosomal recessive; 603813; LDLRAP1 Hypercholesterolemia, familial, modification of; 143890; APOA2 ...
*  Apolipoprotein B deficiency
It is also known as "normotriglyceridemic hypobetalipoproteinemia". Familial hypercholesterolemia Braunwald, Eugene; Hauser, ... such as familial hypercholesterolemia. Treatment may include, niacin or statin or ezetimibe. ...
*  PCSK9
Reduced LDLR levels result in decreased metabolism of LDL-particles, which could lead to hypercholesterolemia. When LDL binds ... Lopez D (2008). "Inhibition of PCSK9 as a novel strategy for the treatment of hypercholesterolemia". Drug News Perspect. 21 (6 ... Norata GD, Tibolla G, Catapano AL (2014-01-01). "Targeting PCSK9 for hypercholesterolemia". Annual Review of Pharmacology and ... Norata GD, Tibolla G, Catapano AL (August 2014). "PCSK9 inhibition for the treatment of hypercholesterolemia: promises and ...
*  Partial ileal bypass surgery
Familial hypercholesterolemia Ileojejunal bypass Buchwald H, Stoller DK, Campos CT, Matts JP, Varco RL (September 1990). " ... Chalstrey LJ, Winder AF, Galton DJ (November 1982). "Partial ileal bypass in treatment of familial hypercholesterolaemia". J R ... "Partial ileal bypass for hypercholesterolemia. 20- to 26-year follow-up of the first 57 consecutive cases". Ann. Surg. 212 (3 ... the procedure is used to treat a number of hyperlipidemias including familial hypercholesterolemia. The only randomized ...
*  Metab-L
"Sitosterolemia Presenting as Pseudohomozygous Familial Hypercholesterolemia". Clin Med Res. 14: 103-8. doi:10.3121/cmr. ...
*  Biosynthesis
Familial hypercholesterolemia: this disorder is characterized by the absence of functional receptors for LDL. Deficiencies in ... "Novel Therapies for Treating Familial Hypercholesterolemia". Current Atherosclerosis Reports. 16 (1). doi:10.1007/s11883-013- ...
*  Alirocumab
Desai NR, Sabatine MS (Feb 2015). "PCSK9 inhibition in patients with hypercholesterolemia". Trends in Cardiovascular Medicine. ... its role in causing some cases of familial hypercholesterolaemia when some mutations are present, and its role in causing very ... from the identification of a new gene in familial hypercholesterolemia towards a potential new class of anticholesterol drugs ... "Cost-effectiveness of PCSK9 Inhibitor Therapy in Patients With Heterozygous Familial Hypercholesterolemia or Atherosclerotic ...
*  Lipid hypothesis
Atherosclerosis Cholesterol Hypercholesterolemia Blood lipids The International Network of Cholesterol Skeptics Medical ... An interpretive history of the cholesterol controversy: part II: the early evidence linking hypercholesterolemia to coronary ... Stehbens WE (2001). "Coronary heart disease, hypercholesterolemia, and atherosclerosis I. False premises". Exp Mol Pathol. 70 ( ... Steinberg D (2002). "Atherogenesis in perspective: hypercholesterolemia and inflammation as partners in crime". Nature Medicine ...
*  Lomitapide
"FDA Approves Aegerion Pharmaceuticals' Juxtapid (lomitapide) Capsules for Homozygous Familial Hypercholesterolemia (HoFH)" ( ... is a drug used as a lipid-lowering agent for the treatment of familial hypercholesterolemia, developed by Aegerion ... in patients with homozygous familial hypercholesterolemia (HoFH)." In a Phase III study, lomitapide led to elevated ... cholesterol in patients with homozygous familial hypercholesterolemia (HoFH). On 31 May 2013 the European Committee for ...
*  Low-density lipoprotein receptor adapter protein 1
2003). "Autosomal recessive hypercholesterolemia in a Sicilian kindred harboring the 432insA mutation of the ARH gene". ... 2002). "Autosomal recessive hypercholesterolaemia in Sardinia, Italy, and mutations in ARH: a clinical and molecular genetic ... 2001). "Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein". Science. 292 ... 2005). "A novel ARH splice site mutation in a Mexican kindred with autosomal recessive hypercholesterolemia". Hum. Genet. 116 ( ...
*  27-Hydroxycholesterol
"27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology". Science. 342 (6162): 1094-8. doi:10.1126/ ...
*  Genetic testing
... non-syndromic deafness Familial hypercholesterolemia Tendon xanthomas; elevated LDL cholesterol; premature heart disease ...
*  Arcus senilis
It can also appear earlier in life as a result of hypercholesterolemia. Arcus senilis can be confused with the limbus sign, ... It can be a sign of disturbance in lipid metabolism, an indicator of conditions such as hypercholesterolemia, ... Xanthelasma Zech Jr, LA; Hoeg, JM (2008). "Correlating corneal arcus with atherosclerosis in familial hypercholesterolemia". ...
*  Endothelial dysfunction
Treatment of hypertension and hypercholesterolemia are also critical; the major pharmacological interventions to improve ...
*  Locus heterogeneity
Other examples are hypertrophic cardiomyopathy, osteogenesis imperfecta, Familial hypercholesterolemia. Allelic heterogeneity ...
*  Atorvastatin
Heterozygous familial hypercholesterolemia in pediatric patients Homozygous familial hypercholesterolemia Hypertriglyceridemia ... Hypercholesterolemia (heterozygous familial and nonfamilial) and mixed dyslipidemia (Fredrickson types IIa and IIb) to reduce ... which are fibrates used in accessory therapy in many forms of hypercholesterolemia, usually in combination with statins, ... "Efficacy and safety of atorvastatin in children and adolescents with familial hypercholesterolemia or severe hyperlipidemia: a ...
*  Samoyed hereditary glomerulopathy
Past nine months of age, hypercholesterolemia may be seen. In the final stages of the disease, at around 15 months of age for ...