... as Van der Waals forces appear between the hydrophobic radicals (H), surrounded by the hydrophilic amino acids (amphipathic ... This could be due to its interaction with membrane compartments.[citation needed] The EF-hand domain's function still remains ... The position of hydrophobic remains (alpha helix exterior) causes their amphipathic behaviour.[citation needed] The bond ... Each one of these helixes is a repeated 7 amino acid sequence (HPPHCPC), where H refers to hydrophobic amino acids. ...
He gave a reasonable clue, cluster- associated hydrophobic-to-hydrophilic transformation, to understand water adsorption of ... He introduced the concept of quasi-vaporization of supercritical gases through an intensive molecule-pore interaction, giving ...
... which reduces hydrophobic interactions. The more hydrophobic the molecule, the more strongly it will bind to the stationary ... hydrophobic molecules in the polar mobile phase tend to adsorb to the hydrophobic stationary phase, and hydrophilic molecules ... which has a stronger affinity for hydrophobic or less polar compounds. The use of a hydrophobic stationary phase is essentially ... Hydrophobic molecules can be eluted from the column by decreasing the polarity of the mobile phase using an organic (non-polar ...
... easy encapsulation or adsorption of both hydrophobic and hydrophilic molecules, and easy surface modification. PLGA-PEG ... Upon interaction with PLA2, the DNA nanoparticles transformed into nanofibers to deliver TRAIL to death receptors on the cancer ... PLGA was charged at its terminal portions for better electrostatic interaction with IL-10 while PEG was used to functionalize ... PEI protects DNA from degradation in vivo, promotes interaction with negatively charged cell membranes, and enhances release ...
The glycosylation creates a highly hydrophilic region which prevents hydrophobic chemotherapeutic drugs from passing through. ... MUC1 cytoplasmic tail is shuttled to the mitochondria through interaction with hsp90. This interaction is induced through ... This interaction is increased by genotoxic stress. MUC1 and p53 were found to be associated with the p53 response element of ... This interaction was shown to be dependent on cell adhesion. Studies have demonstrated that MUC1 is phosphorylated on a YEKV ...
The renin molecule contains both hydrophobic and hydrophilic amino acids. The hydrophilic ones tend to be on the outside of the ... A hydrophobic interaction with the S3sp subpocket, S1 and S3 contribute to higher potency and affinity. By having a large and ... The S2 pocket is large, bipartite and hydrophobic, but can accommodate both hydrophobic and polar ligands. This diversity of ... and in vitro tests have indicated the interaction with the flap region could be important to affinity. Interaction with both ...
Wing II interacts through π-π interactions with a hydrophobic pocket, formed in most part by the side chains of aromatic amino ... The butterfly structure has a hydrophilic centre as a 'body' and two hydrophobic moieties representing the wings. Wing I is ... On the butterfly body a hydrophobic part fills a small pocket which is mainly formed by the side chains of Lys-103, Val-106 and ... R120393, a DATA analog, was designed with a chloroindole part in wing I to expand interactions with the side chain of conserved ...
MD simulations may observe interactions between targeted lipids, proteins, hydrocarbons, water, hydrophilic/hydrophobic regions ... It is important to consider the size of the hydrophilic region versus the hydrophobic region. For example, if the hydrophilic ... which are amphiphilic molecules that have hydrophilic and hydrophobic regions. The hydrophilic region contains the polar head ... Ethanol's hydrophobic properties are limited and primarily binds close the hydrophilic region of the phospholipid. This bonds ...
The transitions that occur in these systems depend on the polymer composition (molecular weight and hydrophilic/hydrophobic ... The interactions with salts are related to their ability to act as water structure makers (salting-out) or water structure ... The aggregation of several unimers occurs to minimize the interactions of the PPO blocks with the solvent. Thus, the core of ... Among other things, they can be used to increase the water solubility of hydrophobic, oily substances or otherwise increase the ...
By choosing to use hydrophilic polymer coatings, protein adsorption decreases and the chance of negative interactions with the ... The PEG coating consists of hydrophilic molecules that are repulsive to protein adsorption. Proteins consist of hydrophobic ... PTFE is a hydrophobic molecule composed of carbon and fluorine. Carbon-fluorine bonds cause PTFE to be a low-friction material ... Because the ability of a surface to adsorb molecules onto its surface depends on energies of interaction, thermodynamics of ...
Specifically, the function of GSTs in this role is twofold: to bind both the substrate at the enzyme's hydrophobic H-site and ... This technique can be used to elucidate direct protein-protein interactions. A drawback of this assay is that the protein of ... GSH at the adjacent, hydrophilic G-site, which together form the active site of the enzyme; and subsequently to activate the ... Two subgroups of cytosolic GSTs have been characterized based upon their interaction with glutathione: the Y-GST group, which ...
Thus, the separation of hydrophobic/hydrophilic groups cannot be applied to DSCG. The polymer solution serves as the medium or ... but water-soluble molecular interactions. These molecular interactions include hydrogen bonding, pi stacking, and salt bridging ... The strengthening of interfacial molecular interactions in w/w emulsions results in the formation of a layer of polymer that ... 2. As the droplet size increases, the molecular interactions at the interface of the droplet phase and the continuous phase ...
... which rank amino acids from most hydrophobic to most hydrophilic, consistently place cysteine towards the hydrophobic end of ... Hydrophobic interactions of the cystein side chain in micelles". Eur. J. Biochem. 3 (3): 346-50. doi:10.1111/j.1432-1033.1968. ... However, the cysteine side chain has been shown to stabilize hydrophobic interactions in micelles to a greater degree than the ... free cysteine residues were found to associate with hydrophobic regions of proteins. Their hydrophobic tendency was equivalent ...
They can encapsulate either hydrophilic or hydrophobic contents and can be used to deliver cargo such as DNA, proteins, or ... In either case, entry into potential host cells requires a favorable interaction between a protein on the surface of the virus ... Most polyplexes consist of cationic polymers and their fabrication is based on self-assembly by ionic interactions. One ...
... a non-polar R group of an amino acid residue can turn a hydrophobic portion of a protein into a polar and extremely hydrophilic ... It is thought that a histone code dictates the expression of genes by a complex interaction between the histones in a ... induce a conformational change in the structure of the protein via long-range allostery with other hydrophobic and hydrophilic ... Phosphorylation introduces a charged and hydrophilic group in the side chain of amino acids, possibly changing a protein's ...
... a non-polar R group of an amino acid residue can turn a hydrophobic portion of a protein into a polar and extremely hydrophilic ... It is thought that a histone code dictates the expression of genes by a complex interaction between the histones in a ... induce a conformational change in the structure of the protein via long-range allostery with other hydrophobic and hydrophilic ... Phosphorylation introduces a charged and hydrophilic group in the side chain of amino acids, possibly changing a protein's ...
... a non-polar R group of an amino acid residue can turn a hydrophobic portion of a protein into a polar and extremely hydrophilic ... It is thought that a histone code dictates the expression of genes by a complex interaction between the histones in a ... induce a conformational change in the structure of the protein via long-range allostery with other hydrophobic and hydrophilic ... Phosphorylation introduces a charged and hydrophilic group in the side chain of amino acids, possibly changing a protein's ...
... a non-polar R group of an amino acid residue can turn a hydrophobic portion of a protein into a polar and extremely hydrophilic ... It is thought that a histone code dictates the expression of genes by a complex interaction between the histones in a ... induce a conformational change in the structure of the protein via long-range allostery with other hydrophobic and hydrophilic ... Phosphorylation introduces a charged and hydrophilic group in the side chain of amino acids, possibly changing a protein's ...
... a non-polar R group of an amino acid residue can turn a hydrophobic portion of a protein into a polar and extremely hydrophilic ... It is thought that a histone code dictates the expression of genes by a complex interaction between the histones in a ... induce a conformational change in the structure of the protein via long-range allostery with other hydrophobic and hydrophilic ... Phosphorylation introduces a charged and hydrophilic group in the side chain of amino acids, possibly changing a protein's ...
... a non-polar R group of an amino acid residue can turn a hydrophobic portion of a protein into a polar and extremely hydrophilic ... It is thought that a histone code dictates the expression of genes by a complex interaction between the histones in a ... induce a conformational change in the structure of the protein via long-range allostery with other hydrophobic and hydrophilic ... Phosphorylation introduces a charged and hydrophilic group in the side chain of amino acids, possibly changing a protein's ...
The main difference in the relevant properties of Cb and silica is that Cb is hydrophobic (as are the polymers used in the ... Because of the higher surface area of the nano-particles, the interaction with the other particles within the mixture is more ... manufacturing of car ties) whereas silica is hydrophilic. So in order to increase the compatibility among the silica fillers ... Super paramagnetic particles are known to display strong interactions with external magnetic fields leading to large saturation ...
These non-covalent interactions consists of a hydrophobic effect, hydrogen bonds, and electrostatic interactions between the ... The catalytic sites contain both a serine and a histidine residue, which are hydrophilic sidechains. The residues require NAD+ ... The interactions between subunits forming a tetramer in SDH is determined by non-covalent interaction. ...
... construction of sophisticated amphiphilic grafted copolymers with hydrophobic polyolefin core and shell based on hydrophilic ... This cation is stabilized by an agostic interaction. β-Hydride elimination then occurs to give a hydride-alkene complex. ...
This hydrophobic core is surrounded by a hydrophilic membrane consisting of phospholipids, free cholesterol, and ... The interaction of these apolipoproteins with enzymes in the blood, with each other, or with specific proteins on the surfaces ... Binding of LDL to its target tissue occurs through an interaction between the LDL receptor and apolipoprotein B-100 on the LDL ... This interaction causes the endocytosis of the chylomicron remnants, which are subsequently hydrolyzed within lysosomes. ...
The hydrocarbon plasma coating increases the non-polar interactions while decreasing polar interactions which allow paper to ... An ideal hydrophobic surface would have a contact angle of 180 degrees to water. This means that the hydrocarbons lie flat ... Cationic starch and hydrophilic agents are also applied, including alkenyl succinic anhydride (ASA) and alkyl ketene dimers ( ... Plasma coating can be used to add hydrocarbons to surfaces which can make a surface non-polar or hydrophobic. The specific type ...
The α-Helices and β-Sheets are commonly amphipathic, meaning they have a hydrophilic and a hydrophobic portion. This ability ... Once the protein's tertiary structure is formed and stabilized by the hydrophobic interactions, there may also be covalent ... The hydrophobic effect is the phenomenon in which the hydrophobic chains of a protein collapse into the core of the protein ( ... Folding is a spontaneous process that is mainly guided by hydrophobic interactions, formation of intramolecular hydrogen bonds ...
The protein consists of alternating hydrophobic and hydrophilic domains, which are encoded by separate exons, so that the ... Tropoelastin aggregates at physiological temperature due to interactions between hydrophobic domains in a process called ... The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions ... The hydrophilic domains contain Lys-Ala (KA) and Lys-Pro (KP) motifs that are involved in crosslinking during the formation of ...
There is some evidence that both hydrophobic (tails straight) and hydrophilic (heads curved around) pores can coexist. Fusion ... also called the hydrophobic effect). This complex process includes non-covalent interactions such as van der Waals forces, ... Biological bilayers are usually composed of amphiphilic phospholipids that have a hydrophilic phosphate head and a hydrophobic ... The hydrophobic core of the bilayer is typically 3-4 nm thick, but this value varies with chain length and chemistry. Core ...
Hydrophobic, electrostatic, and Van Der Waals Interactions) and protein-solvent interactions. As a result, this process is ... curling up on itself so that hydrophobic elements of the protein are buried deep inside the structure and hydrophilic elements ... The non-covalent interactions between antiparallel strands in DNA can be broken in order to "open" the double helix when ... Protein folding consists of a balance between a substantial amount of weak intra-molecular interactions within a protein ( ...
Lipid bilayers are structures of lipid molecules consisting of a hydrophobic tail and a hydrophilic head group. Therefore, ... is a measure of the hydration interaction energy for hydrophilic molecules of the given system, λR is a characteristic length ... Hydrophobic forces are the attractive entropic forces between any two hydrophobic groups in aqueous media, e.g. the forces ... As water molecules have an affinity towards hydrophilic head groups, they try to arrange themselves around the head groups of ...