Hyaluronic acid
... has been used to treat dry eye. Hyaluronic acid is a common ingredient in skin care products. Hyaluronic acid ... In some cases, hyaluronic acid fillers can result in a granulomatous foreign body reaction. Hyaluronic acid is produced on a ... Hyaluronic acid can be 25,000 disaccharide repeats in length. Polymers of hyaluronic acid can range in size from 5,000 to ... Hyaluronic acid also contains silicon, ranging 350-1,900 μg/g depending on location in the organism. Hyaluronic acid is ...
Treatment of equine lameness
Rheology of hyaluronic acid. Biopolymers 1968;6:777-791. Radin EL, Paul IL. A consolidated concept of joint lubrication. J Bone ... Intravenous formulations of hyaluronic acid (HA) are available under the trade names Legend and Hyonate. In osteochondral ... Additionally, hyaluronic acid levels in synovial fluid have been found to increase following IA injection of corticosteroids. ... Hyaluronic acid (hyaluronan, HA) is naturally occurring component of synovial fluid and the extracellular matrix of articular ...
Injection (medicine)
Hyaluronic acid injection is used to supplement the body's natural synovial fluid and decrease the friction and stiffness of ... Yaftali, Nina A.; Weber, Kathleen (1 January 2019). "Corticosteroids and Hyaluronic Acid Injections". Clinics in Sports ... to help with pain and inflammation to complete replacement of the synovial fluid with a compound such as hyaluronic acid. The ... Some species of ants inject forms of venom which include compounds which produce minor pain such as the formic acid, which is ...
Hyaluronidase
Elevated tissue expression of hyaluronic acid and hyaluronidase validates the hyaluronic acid-hyaluronidases urine test for ... and the degradation of hyaluronic acid into hyaluronic acid oligosaccharides by high HYAL levels result in increased tumor ... Plasma hyaluronic acid is elevated in sepsis and septic shock and correlate with disease severity, but the effect on mortality ... The resulting hyaluronic acid fragments of variable size are then further hydrolyzed by HYAL1 after being internalized into ...
Knee arthritis
"Hyaluronic Acid Injections for Osteoarthritis". arthritis.org. Retrieved 2018-12-23. "Hyaluronic Acid (Injection Route) ... including hyaluronic acid injections), and glucosamine and chondroitin sulphate. Hyaluronic acid is normally present in joints ... Hyaluronic acid injections are an FDA-approved treatment for osteoarthritis of the knee, and are sometimes also used for other ... Bowman S, Awad ME, Hamrick MW, Hunter M, Fulzele S (February 2018). "Recent advances in hyaluronic acid based therapy for ...
Streptococcus zooepidemicus
The fermentation process is regulated by the production of hyaluronic acid. When high concentrations of the hyaluronic acid by- ... These factors include hyaluronic acid being severely limited, strong competition between hyaluronic synthesis and cell growth, ... Commercial uses for hyaluronic acid include an ingredient in cosmetics, skin filler for anti-aging and lip injections, in ... Since hyaluronic acid is important for the virulence of S. zooepidemicus, as well as a valuable commercial production, ...
Proteoglycan 4
The interaction with hyaluronic acid". Connective Tissue Research. 28 (4): 245-55. doi:10.3109/03008209209016818. PMID 1304440 ... About two thirds of these sugar groups are capped with sialic acid, and the end domains of the glycoprotein are thought to be ... The cDNA encodes a protein of 1,404 amino acids (human A isoform) with a somatomedin B homology domain, heparin-binding domains ... The oligosaccharides are O-linked both with and without sialic acid. Electron microscope measurements show that the lubricin ...
Sanofi
Synvisc (Hyaluronic acid), for knee pain. - Urology Ditropan XL (Oxybutynin chloride), for bladder relief, marketed by Janssen ... Depakine (Valproic acid), for epilepsy, now owned by AbbVie. Depakote (Valproate semisodium), for epilepsy, now owned by AbbVie ... Skelid (Tiludronic acid), for Paget's disease of bone. Soliqua (insulin glargine/lixisenatide), for type 2 diabetes mellitus. ... Sculptra (Polylactic acid), for facial fat loss. Thyrogen (Thyroid-stimulating hormone), for thyroid cancer. - Over the counter ...
Sodium hyaluronate
Hyaluronic acid sodium salt Biochem/physiol Actions Hyaluronic Acid Legal Information Boucher WS, Letourneau R, Huang M, ... Sodium hyaluronate, as hyaluronic acid, is distributed widely in the extracellular matrix of mammalian connective, epithelial, ... Witting M, Boreham A, Brodwolf R, Vávrová K, Alexiev U, Friess W, Hedtrich S (May 2015). "Interactions of hyaluronic Acid with ... Kuehl C, Zhang T, Kaminskas LM, Porter CJ, Davies NM, Forrest L, Berkland C (June 2016). "Hyaluronic Acid Molecular Weight ...
Vocal cords
Hyaluronic acid plays a very important role in the vocal fold biomechanics. In fact, hyaluronic acid has been described as the ... if the production of hyaluronic acid and collagen is not balanced, which means the hyaluronic acid level is lower than normal, ... showed than the hyaluronic acid content was higher in male than in female vocal cords. Bentley et al. demonstrated that sex ... observed that the hyaluronic acid content in the vocal fold lamina propria was significantly higher in males than in females. ...
Alginic acid
Hyaluronic acid: a polysaccharide in animals. Agar Davies, JC (2002). "Pseudomonas aeruginosa in cystic fibrosis: pathogenesis ... Alginic acid is a linear copolymer with homopolymeric blocks of (1→4)-linked β-D-mannuronate (M) and α-L-guluronate (G) ... Alginic acid, also called algin, is a naturally occurring, edible polysaccharide found in brown algae. It is hydrophilic and ... Sodium alginate (NaC6H7O6) is the sodium salt of alginic acid. Sodium alginate is a gum. Potassium alginate (KC6H7O6) is the ...
Intracytoplasmic sperm injection
This is because only mature sperm have a receptor for hyaluronic acid, which they need because this acid can be found ... Sperms selected by hyaluronic acid has about no effect on whether a live birth results, but may reduce miscarriage. The first ... In this case, they are placed on a plate containing drops of a synthetic compound similar to hyaluronic acid. We will know ... Parmegiani L, Cognigni GE, Ciampaglia W, Pocognoli P, Marchi F, Filicori M (January 2010). "Efficiency of hyaluronic acid (HA) ...
Contact inhibition
Hyaluronic acid synthase Abercrombie, M. (September 1970). "Contact inhibition in tissue culture". In Vitro. 6 (2): 128-142. ...
Ann Stone Minot
Hunt, John S.; Minot, Ann S. (January 1949). "Hyaluronic acid-hyaluronidase enzyme system in pemphigus". Archives of ...
Plastic surgery
One type of dermal filler is Hyaluronic acid. Hyaluronic acid is naturally found throughout the human body. It plays a vital ... Development within this field has occurred over time with synthetic forms of hyaluronic acid is being created, playing roles in ... such as hyaluronic acid Brachioplasty ("Arm lift"): reducing excess skin and fat between the underarm and the elbow Laser Skin ... alongside hyaluronic acid based dermal fillers. Biomaterial Body modification Cosmetic surgery in Australia Dental trauma ...
Joint injection
Hyaluronic acid, because of its high viscosity, is sometimes used to replace bursa fluids. The technique may be used to also ... Injections of hyaluronic acid have not produced improvement compared to placebo for knee arthritis, but did increase risk of ... Wen, Dennis Y (1 August 2000). "Intra-articular Hyaluronic Acid Injections for Knee Osteoarthritis". American Family Physician ... Witteveen AG, Hofstad CJ, Kerkhoffs GM (October 2015). "Hyaluronic acid and other conservative treatment options for ...
Karl Meyer (biochemist)
Meyer K, Hobby GL, Chaffee E, Dawson MH (January 1940). "The Hydrolysis of Hyaluronic Acid by Bacterial Enzymes". J Exp Med. 71 ...
Santosh G. Honavar
"Nonsurgical management of epiblepharon using hyaluronic acid gel". Ophthalmic Plast Reconstr Surg. 26 (3): 215-7. doi:10.1097/ ...
Bacterial capsule
Bacillus anthracis Streptococcus pyogenes synthesizes a hyaluronic acid capsule. Streptococcus pneumoniae has at least 91 ... Most bacterial capsules are composed of polysaccharide, but some species use other materials, such as poly-D-glutamic acid in ... Streptococcus agalactiae produces a polysaccharide capsule of nine antigenic types that all contain sialic acid (Ia, Ib, II, ... Staphylococcus aureus Lactococcus garvieae synthesizes capsular gene clusters and some time synthesizes a hyaluronic acid ...
Stretch marks
Hyaluronic acid also improves the appearance of stretch marks. Topical tretinoin is categorized by the FDA as a known teratogen ... Various efforts that have been tried including laser treatments, glycolic acid, and microdermabrasion. Tretinoin (0.1% w/w), ...
Chondroprotection
Endogenous molecules include hyaluronic acid, glucosamine, and chondroitin sulfate. Felson, David T.; Kim, Young-Jo (2007). " ...
PH-sensitive polymers
Examples include chitosan, hyaluronic acid, alginic acid and dextran. Chitosan, a frequently used example, is cationic. Since ... Examples of acidic functional groups include carboxylic acids (-COOH), sulfonic acids (-SO3H), phosphonic acids, and boronic ... Alginic acid, on the other hand, is anionic. It is often evaluated as a calcium-salt for drug delivery applications( ... Muzammil I, Li Y, Lei M. Tunable wettability and pH-responsiveness of plasma copolymers of acrylic acid and ...
Gunnar Blix
He also conducted extensive studies of hyaluronan (hyaluronic acid). He discovered and named sialic acids in 1952. Blix was ... In 1933 he discovered that sulfatide in the brain contained amide-bound fatty acid and 4-sphingenine. Along with Arne Tiselius ... 19-. ISBN 978-1-85573-570-5. Lundblad, A. (May 2015). "Gunnar Blix and his discovery of sialic acids. Fascinating molecules in ...
Tatiana Segura
"Crosslinked hyaluronic acid hydrogels: a strategy to functionalize and pattern". Biomaterials. 26 (4): 359-371. doi:10.1016/J. ...
Bacillus subtilis
"Sodium hyaluronate frequently asked questions, hyaluronic acid FAQs, HA - Hyasis® , Novozymes Biopharma". Archived from the ... It is used to produce hyaluronic acid, which is used in the joint-care sector in healthcare[full citation needed] and cosmetics ... Competence in B. subtilis is induced toward the end of logarithmic growth, especially under conditions of amino-acid limitation ... from wheat bread and strategy for their control by lactic acid bacteria". Applied and Environmental Microbiology. 69 (4): 2321- ...
Yuzurihara
Hyaluronic acid is used in many topical skin serums and creams for anti-aging. This is chemically related to naturally ... The villagers of Yuzurihara were found to have high levels of hyaluronic acid in their diet, which is the main reason why their ... Davids, 2015 Japonica, 2011 ( Babel, 2011 Davids, K (2015). Hyaluronic Acid: Experience Skin and Joint Health Benefits (Google ...
Bovhyaluronidase azoximer
Kim MS, Youn S, Na CH, Shin BS (2015). "Allergic reaction to hyaluronidase use after hyaluronic acid filler injection". Journal ... Its current off-label uses include dissolving hyaluronic acid fillers, treating granulomatous foreign body reactions, and ... The active ingredient belongs to the hyaluronidases family of enzymes that catalyse the degradation of hyaluronic acid. By ...
Fat transfer
Filling with Hyaluronic Acid". Plastic and Reconstructive Surgery Global Open. 7 (1): e2073. doi:10.1097/GOX.0000000000002073. ...
Polysulfated glycosaminoglycan
PSGAG inhibits many of the catabolic enzymes that degrade cartilage, proteoglycans, and hyaluronic acid. The enzymes that are ... PSGAG also stimulates the synthesis of glycosaminoglycans, hyaluronic acid, and collagen, which increase synovial viscosity. It ... where hyaluronic acid is the stem and the side chains are the bristles. When pressure is exerted on the joint, fluids move ... lysosomal enzymes that cause proteoglycans to dissociate from hyaluronic acid; elastase; metalloproteinases such as stromelysin ...
Chin augmentation
Common temporary fillers include hyaluronic acid and calcium hydroxyapatite preparations. Permanent fillers, like "free" ...