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*  Human umbilical vein endothelial cell
Play media Human umbilical vein endothelial cells (HUVECs) are cells derived from the endothelium of veins from the umbilical ... "Human umbilical vein endothelial cells and human dermal microvascular endothelial cells offer new insights into the ... Human umbilical vein endothelial cells at the US National Library of Medicine Medical Subject Headings (MeSH) Primary Umbilical ... Like human umbilical artery endothelial cells they exhibit a cobblestone phenotype when lining vessel walls. Park HJ, Zhang Y, ...
*  PTX3
"IL-1 inducible genes in human umbilical vein endothelial cells". Eur. Heart J. 14 Suppl K: 78-81. PMID 8131794. Vouret-Craviari ... "Long pentraxin PTX3 upregulates tissue factor expression in human endothelial cells: a novel link between vascular inflammation ... dendritic cells (DCs), fibroblasts and endothelial cells in response to primary inflammatory signals [e.g., toll-like receptor ... Gershov D, Kim S, Brot N, Elkon KB (November 2000). "C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from ...
*  PFDN1
2004). "Proteomic study of human umbilical vein endothelial cells in culture". Proteomics. 3 (5): 714-23. doi:10.1002/pmic. ... 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi: ... "Cloning of cDNA with possible transcription factor activity at the G1-S phase transition in human fibroblast cell lines". Acta ... Prefoldin subunit 1 is a protein that in humans is encoded by the PFDN1 gene. This gene encodes a member of the prefoldin beta ...
*  PAFAH1B2
"Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876-84. doi: ... "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi:10.1016/j.cell ... Moro F, Arrigo G, Fogli A, Bernard L, Carrozzo R (Jul 1998). "The beta and gamma subunits of the human platelet-activating ... Platelet-activating factor acetylhydrolase IB subunit beta is an enzyme that in humans is encoded by the PAFAH1B2 gene. ...
*  TXNDC5
"Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876-84. doi: ... a novel protein-disulfide isomerase-like protein that is preferentially expressed in endothelial cells acts as a stress ... "The human protein disulfide isomerase gene family". Human Genomics. 6 (6): 6. doi:10.1186/1479-7364-6-6. PMC 3500226 . PMID ... Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. This gene can be co- ...
*  CAPZB
"Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876-84. doi: ... "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi:10.1016/j.cell ... Collins FS, Rossant J, Wurst W (January 2007). "A mouse for all reasons". Cell. 128 (1): 9-13. doi:10.1016/j.cell.2006.12.018. ... Mass spectrometry characterization of human CAPZB at COPaKB Human CAPZB genome location and CAPZB gene details page in the UCSC ...
*  Thymosin beta-4
"Thymosin beta 4 stimulates directional migration of human umbilical vein endothelial cells". FASEB Journal. 11 (6): 474-81. ... Adhesion to endothelial cells of blood vessel walls is pre-requisite for these cells to leave the bloodstream and invade ... blood-cell precursor) stem cells of bone marrow. Work with cell cultures and experiments with animals have shown that ... "Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells". Cell. 38 (3): 745-55 ...
*  ANGPT2
"Thrombin induces increased expression and secretion of angiopoietin-2 from human umbilical vein endothelial cells". Blood. 99 ( ... "Hyperbaric oxygen selectively induces angiopoietin-2 in human umbilical vein endothelial cells". Biochemical and Biophysical ... Acker T, Beck H, Plate KH (October 2001). "Cell type specific expression of vascular endothelial growth factor and angiopoietin ... "Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to ...
*  CLIC2
2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876- ... CLIC2 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) Human CLIC2 genome location and ... Cell Biol. 36 (8): 1599-612. doi:10.1016/j.biocel.2004.01.026. PMID 15147738. Gerhard DS, Wagner L, Feingold EA, et al. (2004 ... Chloride intracellular channel protein 2 is a protein that in humans is encoded by the CLIC2 gene. Chloride channels are a ...
*  PHPT1
2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876- ... 2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. ... 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs ... 14 kDa phosphohistidine phosphatase is an enzyme that in humans is encoded by the PHPT1 gene. GRCh38: Ensembl release 89: ...
*  Annexin A3
2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876- ... 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi: ... Human ANXA3 genome location and ANXA3 gene details page in the UCSC Genome Browser. Ernst JD, Hoye E, Blackwood RA, Jaye D ( ... Annexin A3 is a protein that in humans is encoded by the ANXA3 gene. It is abnormally expressed in fetuses of both IVF and ICSI ...
*  ECHS1
2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876- ... Jiang LQ, Wen SJ, Wang HY, Chen LY (2003). "Screening the proteins that interact with calpain in a human heart cDNA library ... Enoyl Coenzyme A hydratase, short chain, 1, mitochondrial, also known as ECHS1, is a human gene. The protein encoded by this ... 1993). "Human liver protein map: a reference database established by microsequencing and gel comparison". Electrophoresis. 13 ( ...
*  GDI2
2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876- ... 1995). "Cloning of a brain-type isoform of human Rab GDI and its expression in human neuroblastoma cell lines and tumor ... "Impairment of bile salt-dependent lipase secretion in human pancreatic tumoral SOJ-6 cells". J. Cell. Biochem. 79 (4): 628-47. ... 2003). "Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function ...
*  PFDN5
2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876- ... Prefoldin subunit 5 is a protein that in humans is encoded by the PFDN5 gene. This gene encodes a member of the prefoldin alpha ... Hansen WJ, Cowan NJ, Welch WJ (1999). "Prefoldin-nascent chain complexes in the folding of cytoskeletal proteins". J. Cell Biol ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ...
*  SERPINB9
2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876- ... is present in endothelial and mesothelial cells, suggesting that it protects bystander cells during immune responses". Cell. ... 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi: ... is a primary estrogen-inducible gene in human liver cells". J. Biol. Chem. 275 (8): 5867-73. doi:10.1074/jbc.275.8.5867. PMID ...
*  SH3BGRL
2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876- ... 2006). "Crystal structure of human SH3BGRL protein: the first structure of the human SH3BGR family representing a novel class ... SH3 domain-binding glutamic acid-rich-like protein is a protein that in humans is encoded by the SH3BGRL gene. GRCh38: Ensembl ... "Identification and characterization of a new human gene encoding a small protein with high homology to the proline-rich region ...
*  TPM4
2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876- ... "Assignment of the human alpha-tropomyosin gene TPM4 to band 19p13.1 by fluorescence in situ hybridization". Cytogenet Cell ... Cell. Biol. 24 (20): 9176-85. doi:10.1128/MCB.24.20.9176-9185.2004. PMC 517884 . PMID 15456888. Gerhard DS, Wagner L, Feingold ... Tropomyosin alpha-4 chain is a protein that in humans is encoded by the TPM4 gene. GRCh38: Ensembl release 89: ENSG00000167460 ...
*  DNAJB11
2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876- ... 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi: ... an Hsp40 co-chaperone localized to the endoplasmic reticulum of human cells". J Biol Chem. 275 (32): 24984-92. doi:10.1074/jbc. ... Cell. 16 (1): 40-50. doi:10.1091/mbc.E04-05-0434. PMC 539150 . PMID 15525676. Nakanishi K, Kamiguchi K, Torigoe T, et al. (2005 ...
*  TNFSF12
"Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells". Biochemical and Biophysical ... dendritic cells and natural killer cells. TWEAK can induce apoptosis via multiple pathways of cell death in a cell type- ... This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of ... "TWEAK induces angiogenesis and proliferation of endothelial cells". The Journal of Biological Chemistry. 274 (13): 8455-9. doi: ...
*  RANBP1
2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876- ... In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine ... Cell. Biol. 23 (22): 8124-36. doi:10.1128/MCB.23.22.8124-8136.2003. PMC 262373 . PMID 14585972. Ota T, Suzuki Y, Nishikawa T, ... Cell. Biol. United States. 15 (4): 2117-24. ISSN 0270-7306. PMC 230439 . PMID 7891706. Steggerda, S M; Paschal B M (July 2000 ...
*  Phosphatidylethanolamine
... phosphatidylethanolamine induces angiogenic differentiations in cultured human umbilical vein endothelial cells". FEBS Letters ... Phosphatidylethanolamines are found in all living cells, composing 25% of all phospholipids. In human physiology, they are ... "Amadori-glycated phosphatidylethanolamine up-regulates telomerase activity in PANC-1 human pancreatic carcinoma cells". FEBS ... In humans, metabolism of phosphatidylethanolamine is thought to be important in the heart. When blood flow to the heart is ...
*  TBCA
2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876- ... 2005). "Tubulin cofactor A gene silencing in mammalian cells induces changes in microtubule cytoskeleton, cell cycle arrest and ... "Identification of genes expressed in human CD34+ hematopoietic stem/progenitor cells by expressed sequence tags and efficient ... Tubulin-specific chaperone A is a protein that in humans is encoded by the TBCA gene. The product of this gene is one of four ...
*  Capping protein (actin filament) muscle Z-line, alpha 1
2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876- ... F-actin-capping protein subunit alpha-1 is a protein that in humans is encoded by the CAPZA1 gene. CAPZA1 is a member of the F- ... 2003). "Linking the T cell surface protein CD2 to the actin-capping protein CAPZ via CMS and CIN85". J. Biol. Chem. 278 (25): ... 2007). "The role of CKIP-1 in cell morphology depends on its interaction with actin-capping protein". J. Biol. Chem. 281 (47): ...
*  TNFRSF12A
2003). "Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells". Biochem. Biophys. Res. ... 2003). "The Human Fn14 Receptor Gene Is Up-Regulated in Migrating Glioma Cells in Vitro and Overexpressed in Advanced Glial ... 2006). "Fn14 is upregulated in cytokine-stimulated vascular smooth muscle cells and is expressed in human carotid ... the TNF-like receptor TWEAKR and its ligand TWEAK act downstream of NFAT1 to regulate breast cancer cell invasion". J. Cell Sci ...
*  MPGES-1
"Interleukin 1beta induces functional prostaglandin E synthase in cultured human umbilical vein endothelial cells". J. Physiol. ... Microsomal prostaglandin E synthase-1 (mPGES-1) or Prostaglandin E synthase is an enzyme that in humans is encoded by the PTGES ... 2000). "Human glutathione dependent prostaglandin E synthase: gene structure and regulation". FEBS Lett. 471 (1): 78-82. doi: ... 1989). "Identification of human prostaglandin E synthase: a microsomal glutathione-dependent, inducible enzyme, constituting a ...
*  Mir-126
... miR-126 modulates the expression of epidermal growth factor-like domain 7 in human umbilical vein endothelial cells in vitro ... During apoptosis cell death, cells release apoptotic bodies containing paracrine signals to neighbouring cells. In endothelial ... Mir-126 is a human microRNA that is expressed only in endothelial cells, throughout capillaries as well as larger blood vessels ... Increased expression of mir-126 inhibits cell proliferation of non-small cell lung carcinoma cells in vitro and prevents tomour ...