"Phytosphingosine induces apoptotic cell death via caspase 8 activation and Bax translocation in human cancer cells". Clinical ...
Michael, A; Bajracharya, SD; Yuen, PS; Zhou, H; Star, RA; Illei, GG; Alevizos, I (January 2010). "Exosomes from human saliva as ... ExRNAs are often found packaged within vesicles such as exosomes, ectosomes, prostasomes, microvesicles, and apoptotic bodies. ... cite journal}}: External link in ,ref= (help) NIH request for applications for 'Reference Profiles of Human Extracellular RNA' ... In another study of extracellular mRNAs, mRNAs transported by microvesicles from endothelial progenitor cells (EPCs) to human ...
"Carotenoid derived aldehydes-induced oxidative stress causes apoptotic cell death in human retinal pigment epithelial cells". ...
... human gene location in the UCSC Genome Browser. PDCD7 human gene details in the UCSC Genome Browser. v t e (Articles with ... In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be ... 2004). "The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome". RNA. 10 (6): ... Programmed cell death protein 7 is a protein that in humans is encoded by the PDCD7 gene. This gene encodes a protein with ...
Articles with short description, Short description matches Wikidata, Genes on human chromosome 11, Human proteins). ... July 2019). "The TP53 Apoptotic Network Is a Primary Mediator of Resistance to BCL2 Inhibition in AML Cells". Cancer Discovery ... Chromosome 11 open reading frame 53 is a protein that in humans is encoded by the C11orf53 gene. Reduction in C11orf53 gene ... "C11orf53 chromosome 11 open reading frame 53 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Oláh J, Vincze O, ...
"Crotonaldehyde induces heat shock protein 72 expression that mediates anti-apoptotic effects in human endothelial cells". ... "In vitro transcription of a human hsp 70 heat shock gene by extracts prepared from heat-shocked and non-heat-shocked human ... Duan Y, Huang S, Yang J, Niu P, Gong Z, Liu X, Xin L, Currie RW, Wu T (Mar 2014). "HspA1A facilitates DNA repair in human ... Heat shock 70 kDa protein 1, also termed Hsp72, is a protein that in humans is encoded by the HSPA1A gene. As a member of the ...
Lin CJ, Gong HY, Tseng HC, Wang WL, Wu JL (October 2008). "miR-122 targets an anti-apoptotic gene, Bcl-w, in human ... In humans, miR-122 is encoded at a single genomic locus in chromosome 18. The primary miR-122 transcript (pri-miR-122) is a ... Wilson JA, Sagan SM (August 2014). "Hepatitis C virus and human miR-122: insights from the bench to the clinic". Current ... November 2010). "A novel GSK-3 beta-C/EBP alpha-miR-122-insulin-like growth factor 1 receptor regulatory circuitry in human ...
"Frequent alteration of XAF1 in human colorectal cancers: implication for tumor cell resistance to apoptotic stresses". ... XIAP-associated factor 1 is a protein that in humans is encoded by the XAF1 gene. X-linked inhibitor of apoptosis (XIAP; MIM ... Ng KC, Campos EI, Martinka M, Li G (2004). "XAF1 expression is significantly reduced in human melanoma". J. Invest. Dermatol. ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 17, All stub articles, ...
Karsan A, Yee E, Kaushansky K, Harlan JM (1996). "Cloning of human Bcl-2 homologue: inflammatory cytokines induce human A1 in ... The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a ... Human BCL2A1 genome location and BCL2A1 gene details page in the UCSC Genome Browser. Choi SS, Park IC, Yun JW, et al. (1995 ... Choi SS, Park SH, Kim UJ, Shin HS (1997). "Bfl-1, a Bcl-2-related gene, is the human homolog of the murine A1, and maps to ...
... and C-chains of human complement subcomponent C1q. The complete derived amino acid sequence of human C1q". Biochem. J. 274 (2 ... Functional Complement C1q Abnormality Leads to Impaired Immune Complexes and Apoptotic Cell Clearance. Deciphering the fine ... A novel member of the short chain collagen family located on the human chromosome 1". J. Biol. Chem. 266 (12): 7721-7. doi: ... Genes on human chromosome 1, All articles with unsourced statements, Articles with unsourced statements from May 2021, ...
Apoptosis-inducing factor 1, mitochondrial is a protein that in humans is encoded by the AIFM1 gene on the X chromosome. This ... This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial ... AIFM1 on the Atlas of Genetics and Oncology Human AIFM1 genome location and AIFM1 gene details page in the UCSC Genome Browser ... Phylogenetic analysis indicates that the divergence of the AIFM1 and other human AIFs (AIFM2a and AIFM3) sequences occurred ...
In human pancreatic ß cells, KCNB1, which mediates potassium efflux, produces a downstroke of the action potential in the cell ... Oligomer activation of c-Src and JNK kinases induces the initial pro-apoptotic signal, which is coupled to KCNB1 current. This ... Human immunodeficiency virus type-1 (HIV-1)-associated dementia (HAD) may be driven by an overabundance of glutamate, which in ... Human studies on pulmonary arteries have shown that normal, physiological inhibition of KCNB1 current aids vasoconstriction of ...
Wu Y, Lu Y, Hu Y, Li R (2005). "Cyclic AMP-dependent modification of gonad-selective TAF(II)105 in a human ovarian granulosa ... Yamit-Hezi A, Dikstein R (1998). "TAFII105 mediates activation of anti-apoptotic genes by NF-kappaB". EMBO J. 17 (17): 5161-9. ... Dikstein R, Zhou S, Tjian R (Nov 1996). "Human TAFII 105 is a cell type-specific TFIID subunit related to hTAFII130". Cell. 87 ... Transcription initiation factor TFIID subunit 4B is a protein that in humans is encoded by the TAF4B gene. TATA-binding protein ...
ASPP2 importance in human malignancies is emphasized by studies that show that downregulation of ASPP2 is commonly found in ... The family plays a key role in apoptosis regulation in the intrinsic and extrinsic apoptotic pathways. ASPP1 and ASPP2 promote ... All the amino acids of p53 that are important for binding ASPP2 are mutated in human cancers. ASPP2 expression levels have been ... ASPP2 was first associated with human cancer when the crystal structure of p53 binding domain bound to the C-terminal ankyrin ...
Doulatov S, Notta F, Laurenti E, Dick JE (February 2012). "Hematopoiesis: a human perspective". Cell Stem Cell. 10 (2): 120-36 ... Steady state production of granulocytes is activated after the engulfment of apoptotic granulocytes by tissue macrophages. ... Cowland JB, Borregaard N (September 2016). "Granulopoiesis and granules of human neutrophils". Immunological Reviews. 273 (1): ...
Histone H2B type 1-J is a protein that in humans is encoded by the HIST1H2BJ gene. Histones are basic nuclear proteins that are ... 2003). "Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase". Cell. 113 (4): 507-517. doi: ... 1999). "The human H2A and H2B histone gene complement". Biol. Chem. 380 (1): 7-18. doi:10.1515/BC.1999.002. PMID 10064132. ... Zhong R, Roeder RG, Heintz N (Jan 1984). "The primary structure and expression of four cloned human histone genes". Nucleic ...
Histone H2B type 1-K is a protein that in humans is encoded by the HIST1H2BK gene. Histones are basic nuclear proteins that are ... 2003). "Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase". Cell. 113 (4): 507-17. doi: ... 1999). "The human H2A and H2B histone gene complement". Biol. Chem. 380 (1): 7-18. doi:10.1515/BC.1999.002. PMID 10064132. ... Dobner T, Wolf I, Mai B, Lipp M (1992). "A novel divergently transcribed human histone H2A/H2B gene pair". DNA Seq. 1 (6): 409- ...
Histone H2B type 1-C/E/F/G/I is a protein that in humans is encoded by the HIST1H2BG gene. Histones are basic nuclear proteins ... 2003). "Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase". Cell. 113 (4): 507-17. doi: ... 1997). "Human histone gene organization: nonregular arrangement within a large cluster". Genomics. 40 (2): 314-22. doi:10.1006/ ... Albig W, Kardalinou E, Drabent B, Zimmer A, Doenecke D (Nov 1991). "Isolation and characterization of two human H1 histone ...
Glioma tumor suppressor candidate region gene 2 protein is a protein that in humans is encoded by the GLTSCR2 gene. GRCh38: ... 2007). "GLTSCR2 sensitizes cells to hypoxic injury without involvement of mitochondrial apoptotic cascades". Pathobiology. 74 ( ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 19, All stub articles, ...
In molecular biology, mir-145 microRNA is a short RNA molecule that in humans is encoded by the MIR145 gene. MicroRNAs function ... mediated apoptotic network". Molecular Cancer. 9: 211. doi:10.1186/1476-4598-9-211. PMC 2924312. PMID 20687965. Zaman MS, Chen ... GRCh38: Ensembl release 89: ENSG00000276365 - Ensembl, May 2017 "Human PubMed Reference:". National Center for Biotechnology ... "miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer ...
Ling C, Yao YN, Zheng YG, Wei H, Wang L, Wu XF, Wang ED (October 2005). "The C-terminal appended domain of human cytosolic ... Park SG, Jung KH, Lee JS, Jo YJ, Motegi H, Kim S, Shiba K (June 1999). "Precursor of pro-apoptotic cytokine modulates ... Kim T, Park SG, Kim JE, Seol W, Ko YG, Kim S (July 2000). "Catalytic peptide of human glutaminyl-tRNA synthetase is essential ... Rho SB, Lee JS, Jeong EJ, Kim KS, Kim YG, Kim S (May 1998). "A multifunctional repeated motif is present in human bifunctional ...
"Relationship between Caspase Activity and Apoptotic Markers in Human Sperm in Response to Hydrogen Peroxide and Progesterone". ... TUNEL is a method for detecting apoptotic DNA fragmentation, widely used to identify and quantify apoptotic cells, or to detect ... Negoescu A, Lorimier P, Labat-Moleur F, Drouet C, Robert C, Guillermet C, Brambilla C, Brambilla E (1996). "In situ apoptotic ... Since 1992 the TUNEL has become one of the main methods for detecting apoptotic programmed cell death. However, for years there ...
Release of pro-apoptotic factors was also abrogated as well as a general increase in histone acetylation. A human trial using ... some experiments have been performed on human cells as well as in human drug trials (see table below). There are inherent risks ... Human trials with all of the below HDAC inhibitors are extremely variable and often impacted by the patient's exact SMA subtype ... Human Molecular Genetics. 12 (19): 2481-9. doi:10.1093/hmg/ddg256. PMID 12915451. Tsai LK, Tsai MS, Lin TB, Hwu WL, Li H ( ...
A detailed mechanism of action of apoptotic inducing effect on HCT116 human cancer cell line was elucidated. Through solvent ... Based on acute oral toxicity studies of Swietenia Macrophylla seeds, the consumption of Swietenia Macrophylla by humans is safe ...
Derry JM, Kerns JA, Francke U (December 1995). "RBM3, a novel human gene in Xp11.23 with a putative RNA-binding domain". Human ... RBM3 is cold-induced RNA binding protein and is involved in mRNA biogenesis exerts anti-apoptotic effects. According to ... "Cell atlas - RBM3". The Human Protein Atlas. "Expression of RBM3 in cancer - Summary". The Human Protein Atlas. Danno S, ... Putative RNA-binding protein 3 is a protein that in humans is encoded by the RBM3 gene. This gene is a member of the glycine- ...
v t e (Articles with short description, Short description is different from Wikidata, Genes on human chromosome 5, Human ... 2007). "Repeated recruitment of LTR retrotransposons as promoters by the anti-apoptotic locus NAIP during mammalian evolution ... Baculoviral IAP repeat-containing protein 1 is a protein that in humans is encoded by the NAIP gene. This gene is part of a 500 ... 2002). "Functional human NAIP promoter transcription regulatory elements for the NAIP and PsiNAIP genes". Biochim. Biophys. ...
... "cDNA cloning of a NGFI-B/nur77-related transcription factor from an apoptotic human T cell line". Journal of Immunology. 154 (8 ... Ichinose H, Ohye T, Suzuki T, Sumi-Ichinose C, Nomura T, Hagino Y, Nagatsu T (April 1999). "Molecular cloning of the human ... Chen YH, Tsai MT, Shaw CK, Chen CH (December 2001). "Mutation analysis of the human NR4A2 gene, an essential gene for midbrain ... Mages HW, Rilke O, Bravo R, Senger G, Kroczek RA (November 1994). "NOT, a human immediate-early response gene closely related ...
This subtype could therefore serve as a good model for regulation of apoptotic body formation or blebbing. ATCC U-937 CRL- ... Cellosaurus entry for U937 (CS1 maint: DOI inactive as of August 2023, Human cell lines). ... Lehmann MH (June 1998). "Recombinant human granulocyte-macrophage colony-stimulating factor triggers interleukin-10 expression ... Human Immunology. 67 (11): 894-906. doi:10.1016/j.humimm.2006.08.294. PMC 2269730. PMID 17145369. Parenti S, Sandoni L, ...
Nakashima M, Sonoda K, Watanabe T (1999). "Inhibition of cell growth and induction of apoptotic cell death by the human tumor- ... Receptor-binding cancer antigen expressed on SiSo cells is a protein that in humans is encoded by the EBAG9 gene. This gene was ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... 2001). "Expression of RCAS1 and FasL in human trophoblasts and uterine glands during pregnancy: the possible role in immune ...
The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal ... Leek JP, Carr IM, Bell SM, Markham AF, Lench NJ (Jun 1998). "Assignment of the DNA fragmentation factor gene (DFFA) to human ... Liu X, Zou H, Widlak P, Garrard W, Wang X (May 1999). "Activation of the apoptotic endonuclease DFF40 (caspase-activated DNase ... Abel F, Sjöberg RM, Ejeskär K, Krona C, Martinsson T (February 2002). "Analyses of apoptotic regulators CASP9 and DFFA at ...