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*  Ozarelix
... (developmental code names D-63153, SPI-153) is a peptide gonadotropin-releasing hormone antagonist (GnRH antagonist) ... a fourth generation GnRH antagonist, induces apoptosis in hormone refractory androgen receptor negative prostate cancer cells ... Gonadotropin-releasing hormone receptor § Antagonists List of investigational hormonal agents § GnRH/gonadotropins http:// ...
*  Cetrorelix
... antagonist. A synthetic decapeptide, it is used is used in assisted reproduction to inhibit premature luteinizing hormone ... and follicle-stimulating hormone (FSH). In addition, cetrorelix can be used to treat hormone-sensitive cancers of the prostate[ ... Gonadotropin-releasing hormone receptor § Antagonists http://www.emdserono.com/ms.country.us/en/images/Cetrotide_PI_tcm115_ ... As an alternative to the GnRH antagonist, also a GnRH agonist could be given, but agonist have to be started earlier to ...
*  Gonadotropin-releasing hormone antagonist
Gonadotropin-releasing hormone antagonists (GnRH antagonists) are a class of medications that antagonize the gonadotropin- ... clinical use of agonists and antagonists of luteinizing-hormone-releasing hormone. Nat. Clin. Pract. Endocrinol. Metab.: 3: 157 ... GnRH antagonists are also being investigated in the treatment of women with hormone-sensitive breast cancer and some benign ... Degarelix is a GnRH antagonist that is approved for use in patients with advanced hormone-sensitive prostate cancer throughout ...
*  Hormone antagonist
For the use of hormone antagonists in cancer, see hormonal therapy (oncology) A hormone antagonist is a specific type of ... Hormone antagonists at the US National Library of Medicine Medical Subject Headings (MeSH). ... receptor antagonist which acts upon hormone receptors. Such pharmaceutical drugs are used in antihormone therapy. ...
*  Corticotropin-releasing hormone antagonist
A Corticotropin-Releasing Hormone Antagonist (CRH antagonist) is a specific type of receptor antagonist that blocks the ... Zoumakis E, Rice KC, Gold PW, Chrousos GP (November 2006). "Potential uses of corticotropin-releasing hormone antagonists". ... The main research into clinical CRF antagonists has focused on antagonists selective for the CRF-1 subtype, which is expressed ... a nonselective corticotropin-releasing hormone receptor antagonist, prevents the inhibitory effect of ghrelin on luteinizing ...
*  Progestin-induced virilisation
ISBN 0-07-142280-3. Schardein, James L. (2000). "Hormones and Hormone Antagonists". Chemically Induced Birth Defects (3rd ed ... Maisel, Albert Q. (1965). "Saving the Unborn". The Hormone Quest. New York: Random House. pp. 167-81. OCLC 543168. Gross RE, ... ISBN 0-7216-0376-9. Schardein JL (1980). "Congenital abnormalities and hormones during pregnancy: a clinical review". ...
*  Comparison of birth control methods
Hormone Antagonists for Fertility Regulation. Bombay: Indian Society for the Study of Reproduction and Fertility. Jones RK, ... With an insertion of an IUD (intrauterine device), female or male sterilization, or hormone implant, there is very little ... but don't want to take hormones all the time. Failure rate of repeated or regular use of LNG ECP is similar to rate for those ...
*  Antalarmin
CP-154,526 Pexacerfont Corticotropin-releasing hormone antagonist Zoumakis, E; Rice, K. C; Gold, P.W; Chrousos, G. P (2006). " ... Corticotropin-releasing factor (CRF), also known as Corticotropin-releasing hormone, is an endogenous peptide hormone released ... "Corticotropin releasing hormone (CRH) antagonist attenuates adjuvant induced arthritis: Role of CRH in peripheral inflammation ... "Potential Uses of Corticotropin-Releasing Hormone Antagonists". Annals of the New York Academy of Sciences. 1083: 239-51. ...
*  Pexacerfont
Zoumakis, E; Rice, K. C; Gold, P.W; Chrousos, G. P (2006). "Potential Uses of Corticotropin-Releasing Hormone Antagonists". ... Corticotropin releasing hormone antagonists Antalarmin CP-154,526 Emicerfont Verucerfont "International Nonproprietary Names ... Corticotropin-releasing factor (CRF), also known as corticotropin-releasing hormone, is an endogenous peptide hormone which is ... Pexacerfont (INN, previously known as BMS-562,086) is a drug developed by Bristol-Myers Squibb which acts as a CRF1 antagonist ...
*  Emicerfont
Corticotropin releasing hormone antagonists Antalarmin Pexacerfont Verucerfont Hubbard, CS; Labus, JS; Bueller, J; Stains, J; ... Corticotropin releasing factor (CRF), also known as Corticotropin releasing hormone, is an endogenous peptide hormone which is ... This then triggers the release of corticotropin (ACTH), another hormone which is involved in the physiological response to ... Emicerfont (GW-876,008) is a drug developed by GlaxoSmithKline which acts as a CRF-1 antagonist. ...
*  John Kopchick
A growth hormone antagonist". Endokrynologia Polska. 58 (4): 322-9. PMID 18058724. Zhou, Yihua; Xu, Bixiong C.; Maheshwari, ... During that time, he developed a system built around cloning and expression of growth hormone (GH) genes. In 1987, Dr. Kopchick ... During his time at EBI, he discovered and characterized the molecular aspects of GH receptor antagonists. This discovery was ... Kopchick's groundbreaking work in the field of growth hormone has helped shape the study of endocrinology. John Joseph Kopchick ...
*  Pegvisomant
... (trade name Somavert) is a growth hormone receptor antagonist used in the treatment of acromegaly. It is primarily ... The protein is a modified version of human growth hormone designed to bind to and block the growth hormone receptor. It is ... Pegvisomant blocks the action of growth hormone at the growth hormone receptor to reduce the production of IGF-1. IGF-1 is ... Blocking of the growth hormone receptor reduces feedback control of the growth hormone regulation, leading to approximately ...
*  Ligand (biochemistry)
Conn PM, Rogers DC, Stewart JM, Niedel J, Sheffield T (April 1982). "Conversion of a gonadotropin-releasing hormone antagonist ... Blum JJ, Conn PM (December 1982). "Gonadotropin-releasing hormone stimulation of luteinizing hormone release: A ligand-receptor ... Portoghese PS, Ronsisvalle G, Larson DL, Yim CB, Sayre LM, Takemori AE (1982). "Opioid agonist and antagonist bivalent ligands ... Bivalent ligands were also reported early on by Micheal Conn and coworkers for the gonadotropin-releasing hormone receptor. ...
*  SNAP-7941
Doggrell SA (June 2003). "Does the melanin-concentrating hormone antagonist SNAP-7941 deserve 3As?". Expert Opinion on ... non-peptide antagonist at the melanin concentrating hormone receptor MCH1. In initial animal studies it had promising ... "Lack of efficacy of melanin-concentrating hormone-1 receptor antagonists in models of depression and anxiety". European Journal ... "Synthesis and SAR investigations for novel melanin-concentrating hormone 1 receptor (MCH1) antagonists Part 1. The discovery of ...
*  Prostaglandin antagonist
A Prostaglandin antagonist is a hormone antagonist acting upon prostaglandin. NSAIDs inhibit cyclooxygenase and reduce ... Prostaglandin antagonists at the US National Library of Medicine Medical Subject Headings (MeSH). ...
*  Antithyroid agent
An antithyroid agent is a hormone antagonist acting upon thyroid hormones. The main antithyroid drugs are carbimazole (in the ... Competitive antagonists of thyroid stimulating hormone receptors are currently being investigated as a possible treatment for ... These two markers are an elevated level of thyroid stimulating hormone receptor antibodies (TSHR-Ab) and smoking. A positive ... Lugol's iodine is used to block hormone synthesis before surgery. The mechanisms of action are not completely understood. Some ...
*  Verucerfont
Antalarmin Corticotropin releasing hormone antagonists List of investigational anxiolytics Pexacerfont Zorrilla, Eric P.; ... Corticotropin releasing factor (CRF), also known as Corticotropin releasing hormone, is an endogenous peptide hormone which is ... Verucerfont (GSK-561,679) is a drug developed by GlaxoSmithKline which acts as a CRF-1 antagonist. ... another hormone which is involved in the physiological response to stress. Verucerfont blocks the CRH-1 receptor, and so ...
*  Abarelix
... , sold under the brand name Plenaxis, is an injectable gonadotropin-releasing hormone antagonist (GnRH antagonist) ... Gonadotropin-releasing hormone receptor § Antagonists "Abarelix". PubChem. 2017-07-29. Drugs.com: Abarelix Boccon-Gibod, L.; ... Van Der Meulen, E.; Persson, B. -E. (2011). "An update on the use of gonadotropin-releasing hormone antagonists in prostate ...
*  Hormonal contraception
Hormone Antagonists for Fertility Regulation. Bombay: Indian Society for the Study of Reproduction and Fertility. O'Connor, M.L ... risks for combined-hormone patches are thought to be roughly equivalent to those for combined-hormone pills. Combined oral ... which decreases the release of follicle-stimulating hormone (FSH) and greatly decreases the release of luteinizing hormone (LH ... However, the risk does vary depending on the hormone type or birth control method being used. There are two main classes of ...
*  Hormone therapy
... or hormonal therapy is the use of hormones in medical treatment. Treatment with hormone antagonists may also be ... The most general classes of hormone therapy are oncologic hormone therapy and hormone replacement therapy, of which there are ... of men or sex offenders with paraphilias or hypersexuality Growth hormone therapy for growth hormone deficiency Thyroid hormone ... with low levels of testosterone due to disease or aging Transgender hormone therapy for transgender people Feminizing hormone ...
*  Antiestrogen
... s are one of three types of sex hormone antagonists, the others being antiandrogens and antiprogestogens. ... Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like ... Ethamoxytriphetol (MER-25) was the first antagonist of the ER to be discovered, followed by clomifene and tamoxifen. " ... the ER silent antagonist and selective estrogen receptor degrader (SERD) fulvestrant, aromatase inhibitors (AIs) like ...
*  Antiprogestogen
... s are one of three types of sex hormone antagonists, the others being antiestrogens and antiandrogens. ... Antiprogestogens, or antiprogestins, also known as progesterone antagonists or progesterone blockers, are a class of drugs ... Oct 2006). "Progesterone receptor antagonists". Curr Opin Investig Drugs. 7 (10): 882-90. PMID 17086932. Tang, OS.; Ho, PC. ( ... and the silent antagonist aglepristone. For medical abortion, mifepristone is combined with a prostaglandin (e.g., gemeprost). ...
*  Antiandrogen
Msaouel P, Diamanti E, Tzanela M, Koutsilieris M (2007). "Luteinising hormone-releasing hormone antagonists in prostate cancer ... Gonadotropins include luteinizing hormone (LH) and follicle-stimulating hormone (FSH) and are peptide hormones that signal the ... N-Terminal domain AR antagonists are a new type of AR antagonist that, unlike all currently marketed AR antagonists, bind to ... In contrast to steroidal AR antagonists, nonsteroidal AR antagonists are silent antagonists of the AR and do not activate the ...
*  Melanin-concentrating hormone receptor 1
Shimazaki T, Yoshimizu T, Chaki S (2006). "Melanin-concentrating hormone MCH1 receptor antagonists: a potential new approach to ... Doggrell SA (Jun 2003). "Does the melanin-concentrating hormone antagonist SNAP-7941 deserve 3As?". Expert Opinion on ... Melanin-concentrating hormone receptor 1, also known as MCH1, is one of the melanin-concentrating hormone receptors found in ... "Melanin-concentrating hormone receptor 1 antagonists: a new perspective for the pharmacologic treatment of obesity". Current ...
*  Parathyroid hormone-related protein
Holick MF, Ray S, Chen TC, Tian X, Persons KS (August 1994). "A parathyroid hormone antagonist stimulates epidermal ... Parathyroid hormone-related protein (or PTHrP) is a protein member of the parathyroid hormone family. It is occasionally ... "Entrez Gene: PTHLH parathyroid hormone-like hormone". Cingolani G, Bednenko J, Gillespie MT, Gerace L (December 2002). " ... Vitamins and Hormones. Vitamins & Hormones. 66: 345-84. doi:10.1016/S0083-6729(03)01010-0. ISBN 978-0-12-709866-1. PMID ...
*  7α-Thioprogesterone
The drug has also been assessed at steroid hormone-associated carrier proteins, and shows very low binding to sex hormone- ... Cutler GB, Pita JC, Rifka SM, Menard RH, Sauer MA, Loriaux DL (1978). "SC 25152: A potent mineralocorticoid antagonist with ... Pugeat MM, Dunn JF, Nisula BC (1981). "Transport of steroid hormones: interaction of 70 drugs with testosterone-binding ...
*  Astressin-B
... (AST) is a nonselective corticotropin releasing hormone antagonist that reduces the synthesis of ACTH and cortisol ... a nonselective corticotropin-releasing hormone receptor antagonist, prevents the inhibitory effect of ghrelin on luteinizing ... "CRF Receptor Antagonist Astressin-B Reverses and Prevents Alopecia in CRF Over-Expressing Mice". PLoS ONE. 6: e16377. doi: ... Miwa Y, Nagase K, Oyama N, Akino H, Yokoyama O (March 2011). "Effect of corticotropin-releasing factor receptor antagonist on ...