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*  Methylenetetrahydrofolate reductase deficiency
The resulting enzyme is thermolabile and in homozygotes, enzymatic activity is depressed to 35% of its usual level. The second ...
*  Huntington's disease
"Homozygotes for Huntington's disease". Nature. 326 (6109): 194-197. doi:10.1038/326194a0. PMID 2881213. Squitieri F, Gellera C ...
*  Birt-Hogg-Dubé syndrome
Homozygotes do not survive to birth. When a wild-type FLCN gene was added, the phenotype was rescued. Knockout mice have been ... Homozygotes die in utero. Citations Genetics Home Reference. Andrews 2011. Reese et al. 2009. Palmirotta et al. 2010. Toro 2008 ...
*  Monocarboxylate transporter 8
Female homozygote mutants had decreased circulating glucose levels. Male hemizygous mutants had an increased susceptibility to ...
*  Quantitative genetics
The allele effect is the average phenotypic deviation of the homozygote from the mid-point of the two contrasting homozygote ... They therefore produce f p 0 {\textstyle fp_{0}} "AA" homozygotes plus f q 0 {\textstyle fq_{0}} "aa" homozygotes. Adding these ... homozygote; ( q 0 2 + f p 0 q 0 ) {\textstyle \left(q_{0}^{2}+fp_{0}q_{0}\right)} for the "aa" homozygote; and 2 p 0 q 0 − f ( ... The central value he chose for the gene was the midpoint between the two opposing homozygotes at the one locus. The deviation ...
*  Polymorphism (biology)
... the typical homozygote; the rare homozygote (bimacula) and the heterozygote (medionigra). It was studied there by Ford and ... Heterosis (or heterozygote advantage): "Heterosis: the heterozygote at a locus is fitter than either homozygote". Frequency ... since neither homozygote can reach 100% of the population. For this reason, it is likely that the carbonaria allele was in the ... homozygote and also the heterozygote is normal (though heterozygote individuals will suffer periodic problems). The sickle-cell ...
*  Polymorphism in Lepidoptera
... the typical homozygote; the rare homozygote (bimacula) and the heterozygote (medionigra). It was studied there by E. B. Ford, ...
*  Reproductive compensation
Koeslag JH, Schach SR (1985). "On the perpetuation of relic genes having an inviable homozygote". Annals of Human Genetics. 49 ...
*  Zygosity
The cell or organism in question is called a homozygote. True breeding organisms are always homozygous for the traits that are ...
*  Solid black (chicken plumage)
Homozygotes Bl/Bl are white with a faint bluish gray tinge, and blue in feathers with the form of large irregular shaped blobs ... And homozygotes bl+/bl+ are solid black. The mating of "blue" cocks and hens" give an offspring of black, "blue" and whittish ... Homozygotes Ml/Ml are nearly all black especially in combination with some recessive alleles of the E allelic series such as eb ... Melanotic is considered incompletely dominant because heterozygotes are unlike either homozygote. Australorp Breda Castilian ...
*  High Resolution Melt
... a closed-tube method for differentiating homozygotes and heterozygotes". Clin. Chem. 49 (3): 396-406. doi:10.1373/49.3.396. ... ", "Heterozygote" or "Homozygote" respectively. Each gives a melt curve that is slightly different. With a high quality HRM ...
*  RHOBTB3
Homozygote mutant males had a decreased body weight and abnormal tooth morphology; females had decreased forepaw grip strength ...
*  History of Tay-Sachs disease
Detection of heterozygotes and homozygotes by serum hexaminidase assay". New England Journal of Medicine. 283 (1): 15-20. doi: ...
*  Solid white (chicken plumage)
Although homozygotes I/I have always a solid white plumage color, heterozygous I/i+ chicks are generally black spotted, while ... Homozygotes for this plumage color mutant have white plumage, whereas heterozygotes for the gene show a diluted plumage color. ... Homozygotes die in an early phase of embryonic development. Kokemüller (1935) described a sex-linked albinism in the budgerigar ...
*  GM2 gangliosidoses
Detection of heterozygotes and homozygotes by serum hexaminidase assay". New England Journal of Medicine. 283 (1): 15-20. doi: ...
*  Dog coat genetics
Heterozygotes (R/r) have wavy hair that is easily distinguishable from either homozygote. Wavy hair is considered desirable in ... H/h heterozygotes are harlequin and h/h homozygotes are non-harlequin. Breeding data suggests that homozygous H/H is embryonic ...
*  Butyrylcholinesterase
In the absence of the relaxant, the homozygote is at no known disadvantage. Finally, pseudocholinesterase metabolism of ...
*  Pseudolinkage
During meiosis in a translocation homozygote, chromosomes segregate normally according to Mendelian principles. Even though the ...
*  Familial hypercholesterolemia
The plasma LDL levels are inversely related to the activity of LDL receptor (LDLR). Homozygotes have LDLR activity of less than ... Having two abnormal copies (homozygote) causes accelerated atherosclerosis in childhood, including its complications. ... recessive hypercholesterolemia tend to have more severe disease than LDLR-heterozygotes but less severe than LDLR-homozygotes. ...
*  SEC24A
Male homozygotes had decreased circulating cholesterol and LDL cholesterol levels. "SEC24 family, member A (S. cerevisiae)". ...
*  Human genetics
X-linked dominant inheritance will show the same phenotype as a heterozygote and homozygote. Just like X-linked inheritance, ...
*  HLA-DQ2
Of the DQ2 homozygotes who eat wheat, lifelong risk is between 20 and 40% for coeliac disease. The relationship of DQ2 and ... Double homozygotes (of DQA1 and DQB1) can only form DQ2.5cis. This occurs when a person inherits a DQ2.5cis bearing chromosome ... DQ2.2/DQ2.2 DQ2.2 homozygotes represent about 1.1% of the celiac population, this is not high relative to controls, but it is ... These partial homozygotes in the Dutch CD population are approximately 20%, as compared to a randomly expected 3% indicating a ...
*  Dominant white
It is also possible that the varied origins of Pulos and Hutt's white horses might be responsible for the lack of homozygotes. ... The possibility that any of these might have been homozygotes is refuted by the fact that similar conditions caused death of ... Wriedt described a range of what he considered to be homozygote phenotypes: all-white, white with pigmented flecks, or ... or a homozygote. When an individual inherits two different alleles, one from each parent, it is heterozygous or a heterozygote ...
*  Champagne gene
ch/ch recessive homozygotes are not affected by champagne and have no true champagne traits. CH/ch heterozygotes have one ... "The homozygote may differ by having less mottling or a slightly lighter hair color than the heterozygote." International ... However the 2008 study that mapped the gene and identified it as a dominant trait noted in passing that homozygotes may have ... CH/CH homozygotes (homozygous champagnes) have no wildtype non-champagne alleles. Such horses are indistinguishable from ...
*  Cream gene
C/C recessive homozygotes are not affected by cream and have no true cream traits. C/CCr heterozygotes have one cream allele, ... CCr/CCr homozygotes (homozygous creams) have no wildtype non-cream alleles. The red and black pigment in the hair are diluted ... but it is also visible in CCr/CCr homozygotes: perlinos (homozygous cream on a bay coat) often retain points that are a darker ... may be lethal in homozygote embryos. Another specific mutation on the endothelin receptor type B (EDNRB) gene is associated ...