Ambrus M, Hernádi E, Bajtai G (May 1977). "Prevalence of HLA-A1 and HLA-B8 antigens in selective IgA deficiency". Clin. Immunol ... HLA A1-B8 (Also:HL A1,8; HL A1,A8; HLA A1-Cw7-B8; HLA A*01-B*08, HLA A*0101-B*0801, HLA A*0101-Cw*0701-B*0801; HLA A*01:01-C*07 ... A1-B8 serotype was associated with a number of diseases as "HL-A"' antigens were first being described. Among these were ... In Europe A1-B8 is found, generally as part of the HLA A1-B8-DR3-DQ2 haplotype. This haplotype is 4.7 million nucleotides in ...

... , previously known as HL-A8 was one of the first identified of the HLA antigens. It coined the "Super B8" haplotype, also ... HLA-B8 (B8) is an HLA-B serotype. The serotype identifies the HLA-B*08 gene products. (For terminology help see: HLA-serotype ... B8 is a component gene-allele of the AH8.1 haplotype in Northern and Western Europeans. Genes between B8 and DR3 on this ... Tissue Antigens. 75 (4): 291-455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336. derived from IMGT/HLA ...

March 2000). "The human UTY gene encodes a novel HLA-B8-restricted H-Y antigen". Journal of Immunology. 164 (5): 2807-14. doi: ... "UTY gene codes for an HLA-B60-restricted human male-specific minor histocompatibility antigen involved in stem cell graft ... This protein is a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. Alternative ...

"Primary structure shows HLA-B59 to be a hybrid of HLA-B55 and HLA-B51, and not a subtype of HLA-B8". Tissue Antigens. 41 (4): ... HLA-B59 (B59) is an HLA-B serotype. The serotype identifies the more common HLA-B*## gene products. B59 is a hybrid between B* ... "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291-455. doi:10.1111/j.1399-0039.2010.01466.x. PMC ... For terminology help see: HLA-serotype tutorial) Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich ...

... antigens were first being described. The associations rapidly expanded to include 'HL-A8' HLA-B8, as the HLA A1 and B8 were ... "HL-A antigens in congenital rubella and the role of antigens 1 and 8 in the epidemiology of natural rubella". Tissue Antigens. ... HLA-A1 (A1) is a human leukocyte antigen serotype within HLA-A "A" serotype group. The serotype is determined by the antibody ... B8 in allergic disease, these are found to link to extended HLA A1-B8 region. Oddly, A1 was also found associated with ...

The class I region of these supertype is HLA A1-B8 haplotype, HLA A3-B7, HLA-A2-B7 and HLA A24-B7. Arce-Gomez B, Jones EA, ... HLA-Cw7 (Cw7) is a human leukocyte antigen serotype within HLA-C serotype group. (For more general information on HLA serotypes ... "The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin". Tissue Antigens. 11 ... Tissue Antigens. 61 (5): 403-407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. (HLA-C alleles). ...

... role of HLA-B8, −DRB1*0301, and −DQB1*0201 haplotype in clinical variations of the disease". Tissue Antigens. 70 (4): 301-6. ... and HLA DQA1*0501 and HLA DQB1*0201 alleles. DRB1*0301 is frequently within by the "Super-B8" or ancestral HLA haplotype: A* ... DR17 is part of the broader antigen group HLA-DR3 and is very similar to the group HLA-DR18. DR17 recognizes the DRB1*0301, * ... HLA-DR17 (DR17) is an HLA-DR serotype that recognizes the DRB1*0301 and *0304 gene products. DR17 is found at high frequency in ...

... hla-b antigens MeSH D23.050.301.500.450.380.383 - hla-b7 antigen MeSH D23.050.301.500.450.380.385 - hla-b8 antigen MeSH D23.050 ... hla-b antigens MeSH D23.050.705.552.400.380.383 - hla-b7 antigen MeSH D23.050.705.552.400.380.385 - hla-b8 antigen MeSH D23.050 ... hla-b antigens MeSH D23.050.705.552.450.380.383 - hla-b7 antigen MeSH D23.050.705.552.450.380.385 - hla-b8 antigen MeSH D23.050 ... hla-a antigens MeSH D23.050.301.500.450.370.372 - hla-a1 antigen MeSH D23.050.301.500.450.370.374 - hla-a2 antigen MeSH D23.050 ...

March 2000). "HLA genes in Arabic-speaking Moroccans: close relatedness to Berbers and Iberians". Tissue Antigens. 55 (3): 239- ... September 2008). "Autoimmune-associated HLA-B8-DR3 haplotypes in Asian Indians are unique in C4 complement gene copy numbers ... Müller CR, Ehninger G, Goldmann SF (January 2003). "Gene and haplotype frequencies for the loci hLA-A, hLA-B, and hLA-DR based ... HLA class II typing (HLA-DRB1, DQA1, and DQB1) of Sardinians revealed that they fell outside of the European cluster and tended ...

HLA-DR3-DQ2 is found in HLA A1-B8-DR3-DQ2 haplotype in Northern Europeans (including the British Ilse, Ireland, Iceland). HLA ... Sirén M, Sareneva H, Lokki M, Koskimies S (1996). "Unique HLA antigen frequencies in the Finnish population". Tissue Antigens. ... Klemola T, Savilahti E, Koskimies S, Pelkonen P (1988). "HLA antigens in IgA deficient paediatric patients". Tissue Antigens. ... C regions of the HLA gene complex in northern and northwestern Europe. The linked haplotype is HLA A1-B8-DR3-DQ2 (AH8.1 in the ...

... antigens' serotypes. DR3 is a component gene-allele of the AH8.1 haplotype in Northern and Western Europeans. Genes between B8 ... 2007). "Primary sclerosing cholangitis is associated with extended HLA-DR3 and HLA-DR6 haplotypes". Tissue Antigens. 69 (2): ... HLA-DR3 is composed of the HLA-DR17 and HLA-DR18 split ' ... Some DR3 also react with HLA-DR17 and/or HLA-DR18. The DRB1*03: ... DR3 is genetically linked to HLA-DR52, DRB3*02:02 allele, and HLA-DQ2 (DQ2.5). derived from IMGT/HLA Wiencke K, Karlsen TH, ...

HLA-DQ2 and HLA-B8 are generally found in Caucasian patients, while HLA-DR5 is related to Greek and Israeli patients. Multiple ... Studies on the polymorphisms of human leukocyte antigen (HLA)-DR and HLA-DQ gene regions in Sjögren's patients show ... Patients of different ethnic origin carry different HLA-susceptibility alleles, of which HLA-DR and HLA-DQ are involved in the ... Dendritic cells are antigen-presenting cells that process antigen material and present it to other T cells. Following the ...

... A1 and HLA-DPB1, that are found in the MHC Class II (or HLA-D) region in the Human Leukocyte Antigen complex on human ... In the Super B8 complex DP locus is more frequently substituted, either as a result of its distance from other loci, or because ... HLA-DPA1 Alleles HLA-DPB1 Alleles Before the April 2010 HLA nomenclature update, new HLA-DPB1 allele names were assigned within ... HLA-DP is a protein/peptide-antigen receptor and graft-versus-host disease antigen that is composed of 2 subunits, DPα and DPβ ...

... (A3) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody ... A*03:01 modulates increased risk for multiple sclerosis A3-B7 is part of the A3~DQ2 superhaplotype A3-B8 (Romania, svanS) A3~ ... a modifying influence of HLA class I genes in an HLA class II associated autoimmune disease". Tissue Antigens. 55 (2): 140-8. ... "The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin". Tissue Antigens. 11 ...

While there are some diseases associated with the haplotype, the frequency of association is less compared to A1::B8. HLA B7- ... June 2007). "HLA alleles as predisposal factors for postmenopausal osteoporosis in a Greek population". Tissue Antigens. 69 (6 ... Müller C, Ehninger G, Goldmann S (2003). "Gene and haplotype frequencies for the loci hLA-A, hLA-B, and hLA-DR based on over ... HLA B7-DR15-DQ6 is a representation(by serotype) of a common HLA haplotype found in Western Eurasia. The haplotype can be ...

Cw7-B8 (Western Eurasia) Cw1-B46 (China, Indochina) Cw5-B44 (Western Eurasia) HLA-C has been shown to interact with: KIR2DL1, ... "Human leucocyte antigen-C in B chronic lymphocytic leukaemia". Br J Haematol. 135 (4): 517-9. doi:10.1111/j.1365-2141.2006. ... HLA-C, localized proximal to the HLA-B locus, is located on the distal end of the HLA region. Most HLA-C:B haplotypes are in ... HLA-C belongs to the MHC (human = HLA) class I heavy chain receptors. The C receptor is a heterodimer consisting of a HLA-C ...

Complement component 4 Complement component 4B HLA A1-B8-DR3-DQ2 haplotype Complement system Complement deficiency ... The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha ... insulin-dependent diabetes mellitus is associated with C4 allotypes independently of the association with HLA-DQ alleles in HLA ... Blood antigen systems, Complement system, All stub articles, Human chromosome 6 gene stubs). ...

Complement component 4 Complement component 4A HLA A1-B8-DR3-DQ2 haplotype Complement system Complement deficiency ... The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha ... "Genetic polymorphism of C4 in man and localisation of a structural C4 locus to the HLA gene complex of chromosome 6". Nature. ...

"Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291-455. doi:10.1111/j.1399-0039.2010.01466.x. PMC ... Although for DR3-DQ2 the migration appears to be associated with B8 and probably occurred in the early AMH settlement of Europe ... HLA-Cw*16 (Cw*16) is an HLA-C allele-group. The serotype identifies the more common HLA-Cw*16 gene products. This allele group ... 1989). "Three new class I HLA alleles: structure of mRNAs and alternative mechanisms of processing". Immunogenetics. 29 (2): 80 ...

... the peptide-binding point of contact is a specific HLA class I epitope on the exogenous antigen. The complex HLA-F/HLA class I ... The C-pocket, however, differs significantly from that of the HLA-E with similarities to the C pocket of HLA-B8. In the D ... KIR directly interacts with both HLA-F and HLA class-I individually (i.e. no dimerization between HLA-F and HLA class-I is ... "Serum antibodies to human leucocyte antigen (HLA)-E, HLA-F and HLA-G in patients with systemic lupus erythematosus (SLE) during ...

... (A33) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody ... While clearly not showing the level of disequilibrium of the Super B8 haplotype, the level of disequilibrium is high, ... "The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin". Tissue Antigens. 11 ... A33 is a split antigen of the broad antigen serotype A19. A33 is a sister serotype of A29, A30, A31, A32, and A74. A33 is more ...

... (A*02) is a human leukocyte antigen serotype within the HLA-A serotype group. The serotype is determined by the ... A*02:Cw*16 is associated with increased higher viral load in HIV A2-B7 (Node in Netherlands) A2-B5 A2-B51 A2-B52 A2-B8 A2-B13 ... Before this revision, HLA-A*02 was also referred to as HLA-A2, HLA-A02, and HLA-A*2. HLA-A*02 is one particular class I major ... Tissue Antigens. 11 (2): 96-112. doi:10.1111/j.1399-0039.1978.tb01233.x. PMID 77067. "HLA Nomenclature @ hla.alleles.org". ...

This haplotype, HLA A1-B8-DR3-DQ2, is associated with diseases in which HLA-DQ2 has suspect involvement. Direct involvement of ... high-resolution and large sample typing of HLA DR-DQ haplotypes in a sample of European Americans". Tissue Antigens. 62 (4): ... HLA-DQ2 and HLA-DQB1*02 are almost synonymous in meaning. DQ2 β-chains combine with α-chains, encoded by genetically linked HLA ... DQB1*0201 in Europe is frequently found in the HLA A1-B8-DR3-DQ2 haplotype.[citation needed] This allele is linked to several ...

... originating from the human leukocyte antigen (HLA) system. It serves a number of critical functions in immunity, tolerance, and ... Complement component 4A Complement component 4B HLA A1-B8-DR3-DQ2 haplotype Complement system Complement deficiency Sekar A, ... Using protein variants visualized by electrophoresis, the four structural genes were located between HLA-B and HLA-D. More ... Moreover, the two loci are linked to the HLA, or the human analog of the major histocompatibility complex (MHC) on the short ...

MHC class I HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G MHC class II HLA-DM α β HLA-DO α β HLA-DP α1 β1 HLA-DQ α1 α2 β1 β2 β3 HLA-DR α ... Antigen Antigenicity Immunogen Superantigen Allergen Hapten Epitope Linear Conformational Mimotope Tumor antigen Antigen- ... Beta subunits B1 B2 B3 B4 B5 B6 B7 B8 Dimers Cytoadhesin receptor Integrin alpha6beta4 Glycoprotein IIb/IIIa - Heterodimer: ... T cells Antigen receptor - T cell receptor (TCR) Subunits - TRA@ / TRB@ / TRD@ / TRG@ Co-receptors CD8 (CD8α / CD8β) CD4 ...

... of the HLA-DQ protein. HLA-DQ is part of the MHC class II antigen-presenting receptor (also called the human leukocyte antigen ... such as HLA-B8. People of Indian ancestry seem to have a similar risk to those of Western Caucasian ancestry. Population ... The two subunits of the HLA-DQ protein are encoded by the HLA-DQA1 and HLA-DQB1 genes, located on the short arm of chromosome 6 ... Furthermore, around 5% of those people who do develop coeliac disease do not have typical HLA-DQ2 or HLA-DQ8 alleles (see below ...

It has been shown that high resolution HLA typing (HLA-A, HLA-B, HLA-C, HLA-DRB1, HLA-DQB1 and HLA-DPB1) may be relevant in ... By serotyping A1-Cw7-B8-DR3-DQ2) which is called ' 'super B8' ' or ' 'ancestral haplotype' ' and A*03:01 ; C*07:02 ; B*07:02 ; ... There are three major and three minor MHC class I genes in HLA. Major MHC class I HLA-A HLA-B HLA-C Minor genes are HLA-E, HLA- ... HLA-DP α-chain encoded by HLA-DPA1 locus β-chain encoded by HLA-DPB1 locus HLA-DQ α-chain encoded by HLA-DQA1 locus β-chain ...

p. B8. IT, Developed with webControl CMS by Intermark. "Katalin Karikó, Drew Weissman, Philip Felgner, Uğur Şahin, Özlem Türeci ... 1 February 1998). "Association of malaria parasite population structure, HLA, and immunological antagonism". Science. 279 (5354 ... Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial ...

"Super B8" haplotypes has been under positive selection, and appears to be the most characteristic HLA type in NW Europeans ... Al-Toma A, Goerres MS, Meijer JW, Peña AS, Crusius JB, Mulder CJ (2006). "Human leukocyte antigen-DQ2 homozygosity and the ... Bao F, Yu L, Babu S, Wang T, Hoffenberg EJ, Rewers M, Eisenbarth GS (1999). "One third of HLA DQ2 homozygous patients with type ... 2007). "HLA-DQB1*0201 homozygosis predisposes to severe intestinal damage in celiac disease". Scand. J. Gastroenterol. 42 (1): ...