*HLA-A3

... (A3) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody ... The HFE (Hemochromatosis) locus lies between A3 and B7 within the A3::DQ6 superhaplotype. HLA-A3 selects HIV evolution for a ... A*0301 modulates increased risk for Multiple Sclerosis A3-B7 is part of the A3::DQ2 superhaplotype A3-B8 (Romania, svanS) A3- ... A3 is more common in Europe, it is part of the longest known multigene haplotype, A3-B7-DR15-DQ6. A3 is primarily composed of A ...

*List of MeSH codes (D23)

... hla-a1 antigen MeSH D23.050.301.500.450.370.374 --- hla-a2 antigen MeSH D23.050.301.500.450.370.376 --- hla-a3 antigen MeSH ... hla-a1 antigen MeSH D23.050.705.552.400.370.374 --- hla-a2 antigen MeSH D23.050.705.552.400.370.376 --- hla-a3 antigen MeSH ... hla-a1 antigen MeSH D23.050.705.552.450.370.374 --- hla-a2 antigen MeSH D23.050.705.552.450.370.376 --- hla-a3 antigen MeSH ... hla-b antigens MeSH D23.050.301.500.450.380.383 --- hla-b7 antigen MeSH D23.050.301.500.450.380.385 --- hla-b8 antigen MeSH ...

*History and naming of human leukocyte antigens

In the case of B44, the antigen had already been split from the B12 broad antigen group. In 1983, the cDNA sequences of HLA-A3 ... The HLA genes are much older. Variation in HLA major antigens is the cause of transplant rejection, but variation at HLA is ... Human leukocyte antigens (HLA) began as a list of antigens identified as a result of transplant rejection. The antigens were ... An antiserum specific for HLA-A3 will then agglutinate HLA-A3 bearing red blood cells if the concentration of IgM in the ...

*Adoptive cell transfer

Cancer-testes antigen MAGE-A3 is not known to be expressed in any normal tissues. However, targeting an HLA-A*0201-restricted ... Two patients died when treated with an HLA-A1-restricted MAGE-A3-specific TCR whose affinity was enhanced by a site-specific ... Antigen CD19 appears only on B cells, which go awry in lymphoma and leukemia. Loss of B cells can be countered with ... One example of this in the case of T cell adoptive therapy is the addition of chimeric antigen receptors, or CARs, to redirect ...

*HLA-Cw7

The class I region of these supertype is HLA A1-B8 haplotype, HLA A3-B7, HLA-A2-B7 and HLA A24-B7. Arce-Gomez B, Jones EA, ... HLA-Cw7 (Cw7) is a human leukocyte antigen serotype within HLA-C serotype group. (For more general information on HLA serotypes ... "The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin". Tissue Antigens. 11 ... For the serotype Cw7, the alpha chain are encoded by the HLA-Cw*07 allele group and the β-chain are encoded by B2M locus. Cw7 ...

*HLA-B7

A more recent study looked at a number of linked gene-alleles and found I82-2:D6S265-1:HLA-A3:D6S128-2:HLA-F1:D6S105-8 was ... For terminology help see: HLA-serotype tutorial) B7, previously HL-A7, was one of the first 'HL-A' antigens recognized, largely ... HLA-B7 (B7) is an HLA-B serotype. The serotype identifies the more common HLA-B*07 gene products. ( ... A common serologically defined haplotype in Europeans is HLA A3-Cw7-B7-DR15-DQ6.2 which is composed of alleles A*0301:Cw*0701:B ...

*HLA B7-DR15-DQ6

The A*0301 bearing haplotype (HLA A3-B7-DR15-DQ6) is described as the longest known multgene haplotype in humans. The ... One B7-DR2-DQ6 derives from the fact that DR15 is a split antigen of the DR2 broad antigen serotype. The other B7-DR2-DQ1 stems ... HLA B7-DR15-DQ6 is a representation(by serotype) of a common HLA haplotype found in Western Eurasia. The haplotype can be ... HLA A*0201Cw*0702 : B*0702 : DRB1*1501 : DQA1*0102 : DQB1*0602 The gene-allele representation of the haplotype is: HLA A*0301Cw ...

*HLA-DQ

As a variable cell surface receptor on immune cells, these D antigens, originally HL-A4 antigens, are involved in graft versus ... The DQ loci are in close genetic linkage to HLA-DR, and less closely linked to HLA-DP, HLA-A, HLA-B and HLA-C. Different ... Recognize HLA-DQB1*02 gene products which include gene products of the following alleles: HLA-DQB1*02:01 HLA-DQB1*02:02 HLA- ... HLA-DQ (DQ) is encoded on the HLA region of chromosome 6p21.3, in what was classically known as the "D" antigen region. This ...

*HLA-A11

However, A3 and A11 can process and load antigens even when proteosome activity is diminished suggesting an alternative ... HLA-A11 (A11) is a human leukocyte antigen serotype within HLA-A "A" serotype group. The serotype is determined by the antibody ... "The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin". Tissue Antigens. 11 ... Kim SJ, Choi IH, Dahlberg S, Nisperos B, Kim JD, Hansen JA (March 1987). "HLA and leprosy in Koreans". Tissue Antigens. 29 (3 ...

*HLA-A1

"HL-A antigens in congenital rubella and the role of antigens 1 and 8 in the epidemiology of natural rubella". Tissue Antigens. ... regional recombinant between A1-B8 and A2/A3-B7) A1-B13 Uralic A1-B35 (Albania, Belgium, Italy, Greece, France - Eastern ... HLA-A1 (A1) is a human leukocyte antigen serotype within HLA-A "A" serotype group. The serotype is determined by the antibody ... antigens were first being described. The associations rapidly expanded to include 'HL-A8' HLA-B8, as the HLA A1 and B8 were ...

*MAGEA4

2006). "Melanoma antigen A4 is expressed in non-small cell lung cancers and promotes apoptosis". Cancer Res. 66 (9): 4693-700. ... 2001). "High-resolution structure of HLA-A*0201 in complex with a tumour-specific antigenic peptide encoded by the MAGE-A4 gene ... 2006). "Expression of the MAGE-A4 and NY-ESO-1 cancer-testis antigens and T cell infiltration in non-small cell lung carcinoma ... 2006). "Immunohistochemical expression of tumor antigens MAGE-A1, MAGE-A3/4, and NY-ESO-1 in cancerous and benign prostatic ...

*HLA-DQ1

1992). "Association of HLA-B51 and lack of association of class II alleles with Behçet's disease". Tissue Antigens. 40 (1): 22- ... The A3-B7-DR15-DQ1 haplotype indicates relationships in Eurasia that span from Korea to Ireland, indicating some common ... 1994). "HLA-DQA1, -DQB1 and -DRB1 genotyping in Japanese pemphigus vulgaris patients by the PCR-RFLP method". Tissue Antigens. ... HLA-DQ1 is a serotype that covers a broad range of HLA-DQ haplotypes. Historically it was identified as a DR-like alpha chain ...

*Major histocompatibility complex, class II, DQ alpha 1

Todd JA, Fukui Y, Kitagawa T, Sasazuki T (1990). "The A3 allele of the HLA-DQA1 locus is associated with susceptibility to type ... Marsh SG, Bodmer JG (1993). "HLA class II nucleotide sequences, 1992". Tissue Antigens. 40 (5): 229-43. doi:10.1111/j.1399- ... HLA-DQA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha ( ... 1991). "Interaction of CD4 with HLA class II antigens and HIV gp120". Immunogenetics. 34 (2): 121-8. doi:10.1007/BF00211424. ...

*HLA A1-B8-DR3-DQ2

HLA A3-Cw7-B7-DR15-DQ6 (A3::DQ6), had already undergone significant recombination and is nearly equal in frequency to HLA A2- ... "Correlation between acetylcholine receptor antibody titer and HLA-B8 and HLA-DRw3 antigens in myasthenia gravis". Trans Am ... Hammarström L, Smith E, Möller E, Franksson C, Matell G, Von Reis G (August 1975). "Myasthenia gravis: studies on HL-A antigens ... Hirsch TJ, Enlow RW, Bias WB, Arnett FC (October 1981). "HLA-D related (DR) antigens in various kinds of myositis". Hum. ...

*IMP321

... was a randomised open-label four-arm trial comparing a selected set of 8 HLA-A2 melanoma peptide antigens with or without ... Melan-A and MAGE-A3-DP4. This study has been terminated due to a low enrollment rate and has not reported any data. In 2010 ... The investigators for this work used influenza matrix protein antigen and the tumor antigens Melan-A/MART-1 and survivin when ... Subjects who got IMP321 had higher levels of HBsAg antibody in their blood as well as higher levels of antigen-specific T cells ...

*MAGEA3

Melanoma-associated antigen 3 (MAGE-A3) is a protein that in humans is encoded by the MAGEA3 gene. This gene is a member of the ... 2003). "Identification of immunodominant regions among promiscuous HLA-DR-restricted CD4+ T-cell epitopes on the tumor antigen ... The presence of the antigen on tumor cells has been associated with worse prognosis. In one study, high levels of MAGE-A3 in ... 2006). "Immunohistochemical expression of tumor antigens MAGE-A1, MAGE-A3/4, and NY-ESO-1 in cancerous and benign prostatic ...

*Javed Agrewala

p. US Patent WO2012035558 A3. CS1 maint: Multiple names: authors list (link) India portal Medicine portal Memory T cell Human ... "In Silico Tools for Predicting Peptides Binding to HLA-Class II Molecules: More Confusion than Conclusion". J. Proteome Res. 7 ... leukocyte antigen Melatonin Homeostasis Long link - please select award year to see details Please click A and select JN ... US Patent WO2007031832 A3. Google Patents. CS1 maint: Multiple names: authors list (link) Javed Naim Agrewala, Uthaman ...

*LILRA3

however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted ... Leukocyte immunoglobulin-like receptor subfamily A member 3 (LILR-A3) also known as CD85 antigen-like family member E (CD85e), ... Like the closely related LILRA1, LILRA3 binds to both normal and 'unfolded' free heavy chains of HLA class I, with a preference ... "HLA class I allelic sequence and conformation regulate leukocyte Ig-like receptor binding". Journal of Immunology. 186 (5): ...

*Long-term nonprogressor

In particular, strong correlations have been found between possessing the class 1 HLA-B*5701, HLA-B*5703, and/or HLA-B*2705 ... APOBEC3G, or "A3" for short, is a protein that sabotages reverse transcription, the process HIV relies on for its replication. ... 20% of Europeans who have that mutation are called "non secretor" because of their absence of a certain type of antigen that ... A3 usually stops dormant viruses in the human genome, called endogenous retroviruses, from reawakening and causing infections. ...

*Chromosome 6 (human)

HLA-Cw*06:02: gene variation related to psoriasis (6p21.3) LY6G6E encoding protein Lymphocyte antigen 6 complex, locus G6E ( ... ubiquitin protein ligase E3 component n-recognin 2 (6p21.2) UNC5CL: encoding protein Unc-5 homolog C (C. elegans)-like VEGF: ... HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 forms HLA-DR, heterodimer MHC class II, DR (6p21.3) HLA-DPA1 and HLA-DPB1 forms HLA-DR, ... HLA-A, HLA-B, HLA-C: major histocompatibility complex (MHC), class I, A, B, and C loci. (6p21.3) HLA-DQA1 and HLA-DQB1 form HLA ...

*Munir Pirmohamed

Hughes, DA; Vilar, FJ; Ward, CC; Alfirevic, A; Park, BK; Pirmohamed, M (June 2004). "Cost-effectiveness analysis of HLA B*5701 ... Wu, Y; Farrell, J; Pirmohamed, M; Park, BK; Naisbitt, DJ (April 2007). "Generation and characterization of antigen-specific ... doi:10.1097/01.tp.0000114594.21317.a5. PMID 15084935. ... "HLA-B locus in Caucasian patients with carbamazepine ... implications for drug resistance Cost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity ...

*Outline of immunology

MHC class I HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G MHC class II HLA-DM α β HLA-DO α β HLA-DP α1 β1 HLA-DQ α1 α2 β1 β2 β3 HLA-DR α ... A1 A2 A3 A4 A5 A6 A7 A8 A9 A10 A11 AD AE AL (CD11a) AM (CD11b) AV AX (CD11c) Beta subunits B1 B2 B3 B4 B5 B6 B7 B8 Dimers ... Antigen Antigenicity Immunogen Superantigen Allergen Hapten Epitope Linear Conformational Mimotope Tumor antigen Antigen- ... T cells Antigen receptor - T cell receptor (TCR) Subunits - [email protected] / [email protected] / [email protected] / [email protected] Co-receptors CD8 (CD8α / CD8β) CD4 ...

*List of biomolecules

HDL Histamine Histidine Histone Histone methyltransferase HLA antigen Homocysteine Hormone human chorionic gonadotropin (hCG) ... C19H42BrN Chelerythrine Chromomycin A3 Chaparonin Chitin α-Chloralose Chlorophyll Cholecystokinin (CCK) Cholesterol Choline ...

*Coeliac disease

HLA-DQ is part of the MHC class II antigen-presenting receptor (also called the human leukocyte antigen) system and ... 153: 395-409.e3. doi:10.1053/j.gastro.2017.04.009. Comino I, Moreno Mde L, Sousa C (Nov 7, 2015). "Role of oats in celiac ... The two subunits of the HLA-DQ protein are encoded by the HLA-DQA1 and HLA-DQB1 genes, located on the short arm of the sixth ... Furthermore, around 5% of those people who do develop coeliac disease do not have typical HLA-DQ2 or HLA-DQ8 alleles (see below ...

*MAGEC2

2001). "MAGE-E1, a new member of the melanoma-associated antigen gene family and its expression in human glioma". Cancer Res. ... 2007). "A new tumor-specific antigen encoded by MAGE-C2 and presented to cytolytic T lymphocytes by HLA-B44". Cancer Immunol. ... Melanoma-associated antigen C2 is a protein that in humans is encoded by the MAGEC2 gene. This gene is related to members of ... "Entrez Gene: MAGEC2 melanoma antigen family C, 2". Lucas S, De Plaen E, Boon T (2000). "MAGE-B5, MAGE-B6, MAGE-C2, and MAGE-C3 ...

*Antiphospholipid syndrome

HLA-B8, HLA-DR2, HLA-DR3 Race: Blacks, Hispanics, Asians, and Native Americans There is an additional elevated risk of adrenal ... Annexin A5 forms a shield around negatively charged phospholipid molecules, thus reducing their availability for coagulation. ... that use recombinant antigens will not have a false-positive result. Often, this disease is treated by giving aspirin to ... Thus, anti-annexin A5 antibodies increase phospholipid-dependent coagulation steps. The Lupus anticoagulant antibodies are ...