The serotype identifies the B*38 allele products of the HLA-B gene-locus. B38 is a split antigen of the broad antigen B16, and ... Genetics and HLA antigens". Baillière's Clinical Rheumatology. 8 (2): 263-76. doi:10.1016/S0950-3579(94)80018-9. PMID 8076387. ... Linkage studies indicate a factor in the HLA-class I region is more greatly associated, with HLA-B38 so far the only linked ... HLA-B38 (B38) is an HLA-B serotype. ... derived from IMGT/HLA Middleton D, Menchaca L, Rood H, ...
... (A11) is a human leukocyte antigen serotype within HLA-A "A" serotype group. The serotype is determined by the antibody ... "The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin". Tissue Antigens. 11 ... Kim SJ, Choi IH, Dahlberg S, Nisperos B, Kim JD, Hansen JA (March 1987). "HLA and leprosy in Koreans". Tissue Antigens. 29 (3 ... Forbes JF, Morris PJ (May 1972). "Analysis of HL-A antigens in patients with Hodgkin's disease and their families". J. Clin. ...
... (B39) is an HLA-B serotype. The serotype identifies the more common HLA-B*39 gene products. B39 is a split antigen of ... Genetics and HLA antigens". Baillière's Clinical Rheumatology. 8 (2): 263-76. doi:10.1016/S0950-3579(94)80018-9. PMID 8076387. ... Gladman DD, Farewell VT (June 1995). "The role of HLA antigens as indicators of disease progression in psoriatic arthritis. ... Tissue Antigens. 75 (4): 291-455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336. derived from IMGT/HLA ...
Ambrus M, Hernádi E, Bajtai G (May 1977). "Prevalence of HLA-A1 and HLA-B8 antigens in selective IgA deficiency". Clin. Immunol ... HLA A1-B8 (Also:HL A1,8; HL A1,A8; HLA A1-Cw7-B8; HLA A*01-B*08, HLA A*0101-B*0801, HLA A*0101-Cw*0701-B*0801; HLA A*01:01-C*07 ... Müller C, Ehninger G, Goldmann S (2003). "Gene and haplotype frequencies for the loci hLA-A, hLA-B, and hLA-DR based on over ... A1-B8 serotype was associated with a number of diseases as "HL-A"' antigens were first being described. Among these were ...
... (DR5) is a broad-antigen serotype that is further split into HLA-DR11 and HLA-DR12 antigen serotypes. HLA-DR5 (Human ... HLA-DR5 reactive gene products are linked to serology of HLA-DRB3 (HLA-DR52). derived from IMGT/HLA DR8 - 2% Raffoux C, David V ... Leukocyte Antigen DR5) is a protein that is encoded by a gene in the human leukocyte antigen (HLA) complex. The HLA complex is ... HLA-DR5 is a type of HLA class II molecule that is expressed on the surface of immune cells called dendritic cells and ...
"HLA Antigens in Kawasaki Disease". Pediatrics. 61 (2): 252-255. ISSN 0031-4005. PMID 634680. Shigematsu, I; Shibata, S; ...
... papain-solubilized fragments of the human class II MHC antigens HLA-DR1, HLA-DR2, HLA-DR3, HLA-DR4, HLA-DR7, and HLA-DR8 were ... Early work, elucidated the three-dimensional structures of the human class I MHC molecules of HLA-A2, HLA-A68, and HLA-B27. ... "Crystallization of HLA-DR antigens". Res. Immunol. 142 (5-6): 401-407. doi:10.1016/0923-2494(91)90038-k. PMID 1754711.{{cite ... "Complete amino acid sequence of a papain-solubilized human histocompatibility antigen, HLA-B7. 2. Sequence determination and ...
"HLA-DR antigens in rheumatoid arthritis. A Swiss collaborative study; final report. Swiss Federal Commission for the Rheumatic ... HLA-DR1 is not genetically linked to DR51, DR52 or DR53, but is linked to HLA-DQ1 and DQ5 serotypes. Fernández MM, Guan R, ... HLA-DR1 (DR1) is a HLA-DR serotype that recognizes the DRB1*01 gene products. It has been observed to be common among ... Schiff B, Mizrachi Y, Orgad S, Yaron M, Gazit E (1982). "Association of HLA-Aw31 and HLA-DR1 with adult rheumatoid arthritis". ...
One haplotype found in caucasians is the HLA-A1-B37-Cw6-DR10-DQ5. derived from IMGT/HLA White A, Rostom A (1994). "HLA antigens ... HLA-DR10 (DR10) is a HLA-DR serotype that recognizes the DRB1*1001 gene product. The serological reaction of DR10 is relatively ... HLA-DR10 is not genetically linked to DR51, DR52 or DR53, but is linked to HLA-DQ1 and DQ5 serotypes. ... Kübler K, Arndt P, Wardelmann E, Krebs D, Kuhn W, van der Ven K (2006). "HLA-class II haplotype associations with ovarian ...
"HLA-DR antigens in pemphigus among Japanese". Tissue Antigens. 17 (2): 238-9. doi:10.1111/j.1399-0039.1981.tb00689.x. PMID ... HLA-DR4 (DR4) is an HLA-DR serotype that recognizes the DRB1*04 gene products. The DR4 serogroup is large and has a number of ... derived from IMGT/HLA Roudier J (2006). "HLA-DRB1 genes and extraarticular rheumatoid arthritis". Arthritis Research & Therapy ... "Strong association between IgA nephropathy and HLA-DR4 antigen". Kidney Int. 22 (4): 377-82. doi:10.1038/ki.1982.185. PMID ...
Sirén M, Sareneva H, Lokki M, Koskimies S (1996). "Unique HLA antigen frequencies in the Finnish population". Tissue Antigens. ... HLA-DR3-DQ2 is found in HLA A1-B8-DR3-DQ2 haplotype in Northern Europeans (including the British Ilse, Ireland, Iceland). HLA ... Klemola T, Savilahti E, Koskimies S, Pelkonen P (1988). "HLA antigens in IgA deficient paediatric patients". Tissue Antigens. ... "HLA class II polymorphism in Aka Pygmies and Bantu Congolese and a reassessment of HLA-DRB1 African diversity". Tissue Antigens ...
"HL-A antigens in congenital rubella and the role of antigens 1 and 8 in the epidemiology of natural rubella". Tissue Antigens. ... HLA-A1 (A1) is a human leukocyte antigen serotype within HLA-A "A" serotype group. The serotype is determined by the antibody ... antigens were first being described. The associations rapidly expanded to include 'HL-A8' HLA-B8, as the HLA A1 and B8 were ... "HL-A transplantation antigens in subjects susceptible to recrudescent herpes labialis". Tissue Antigens. 6 (4): 257-61. doi: ...
"Frequencies of HLA-A, HLA-B, HLA-DR, and HLA-DQ phenotypes in the United Arab Emirates population". Tissue Antigens. 66 (2): ... HLA-DQ8 (DQ8) is a human leukocyte antigen serotype within the HLA-DQ (DQ) serotype group. DQ8 is a split antigen of the DQ3 ... "HLA-DRB1 and HLA-DQB1 polymorphisms in Pacific Islands populations". Tissue Antigens. 59 (5): 397-406. doi:10.1034/j.1399- ... "HLA antigens in Tlingit Indians with rheumatoid arthritis". Tissue Antigens. 40 (2): 57-63. doi:10.1111/j.1399-0039.1992. ...
... human leukocyte antigen (HLA) genes; major histocompatibility complex (MHC)) to HIV-1, smallpox, trypanosomiasis (African ...
2009). "Human embryonic stem cells hemangioblast express HLA-antigens". J Transl Med. 7 (1): 27. doi:10.1186/1479-5876-7-27. ...
DR15 is part of the older HLA-DR2 serotype group which also contains the similar HLA-DR16 antigens. Serotypes are unknown for ... DQB1*0501 haplotype is associated with systemic lupus erythematosus HLA-DR15 is genetically linked to HLA-DR51 and HLA-DQ6 (HLA ... 2007). "Analysis of HLA antigens in Turkish sarcoidosis patients". South. Med. J. 100 (4): 356-9. doi:10.1097/SMJ. ... 2007). "HLA alleles as predisposal factors for postmenopausal osteoporosis in a Greek population". Tissue Antigens. 69 (6): 592 ...
The serotype identifies the B*44 gene-allele protein products of HLA-B. B44 is a split antigen of the broad antigen B12, and is ... November 1988). "HLA antigens in ankylosing spondylitis associated with Crohn's disease. Increased frequency of the HLA ... derived from IMGT/HLA Johnston DT, Mehaffey G, Thomas J, et al. (June 2006). "Increased frequency of HLA-B44 in recurrent ... HLA-B44 increases recurrent sinopulmonary infections. Protective effects: HLA-B44 appears to be protective against autoimmune ...
... (A69) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody ... "The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin". Tissue Antigens. 11 ... 1998). "HLA class I and class II DNA typing and the origin of Basques". Tissue Antigens. 51 (1): 30-40. doi:10.1111/j.1399- ... 2007). "Analysis of HLA antigens in Turkish sarcoidosis patients". South. Med. J. 100 (4): 356-359. doi:10.1097/SMJ. ...
... (A9) is a broad antigen HLA-A serotype that recognized the HLA-A23 and HLA-A24 serotypes. A*2402 appears to have evolved ... 1992). "HLA antigens in Tlingit Indians with rheumatoid arthritis". Tissue Antigens. 40 (2): 57-63. doi:10.1111/j.1399- ... Fussell H, Thomas M, Street J, Darke C (1996). "HLA-A9 antibodies and epitopes". Tissue Antigens. 47 (4): 307-12. doi:10.1111/j ... Welinder L, Graugaard B, Madsen M (2000). "HLA antigen and gene frequencies in Eskimos of East Greenland". Eur. J. Immunogenet ...
In humans, this is known as the human leukocyte antigen (HLA) system and over 17,000 HLA alleles or genetic variants have been ... Other non-HLA proteins, known as minor histocompatibility antigens, do exist but generally are unable to cause acute rejection ... "Human Leukocyte Antigen (HLA) System - Immunology; Allergic Disorders". Merck Manuals Professional Edition. Merck & Co. ... These antigens are located on the endothelial lining of blood vessels within the transplanted organ and, once antibodies bind, ...
HLA antigens have also been studied in relation to autism. HLA-B27 is the most researched HLA-B allele due to its high ... Human leukocyte antigen (HLA) B27 (subtypes B*2701-2759) is a class I surface antigen encoded by the B locus in the major ... The presence of HLA-B27, as well as HLA-B5701, is significantly common among this group. Human leukocyte antigen M. A. Khan ( ... These theories consider a specific combination of antigen peptide sequence and the binding groove (B pocket) of HLA-B27 (which ...
"Nixon, Douglas". Makgoba, M. W. (1983). Studies on the polymorphism of HLA class II antigens (Thesis). Thesis DPhil--University ... "Common West African HLA antigens are associated with protection from severe malaria". Nature. 352 (6336): 595-600. Bibcode: ... McMichael, A. J.; Ting, A.; Zweerink, H. J.; Askonas, Brigitte A. (1977). "HLA restriction of cell-mediated lysis of influenza ... Barouch, Dan H. (1995). Peptide binding and presentation by HLA-A2 (Thesis). Thesis DPhil--University of Oxford. "Immunology ...
Thus, the ability to generate platelet products ex vivo and platelet products lacking HLA antigens in serum-free media would ... Generated platelets demonstrated an 85% reduction in class I HLA antigens. These platelets appeared to have normal function in ... January 2020). "iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity ... DC-like antigen-presenting cells obtained from human induced pluripotent stem cells can serve as a source for vaccination ...
Simon M, Bourel M, Fauchet R, Genetet B (1976). "Association of HLA-A3 and HLA-B14 antigens with idiopathic haemochromatosis". ... HLA) region of the genome. It took 20 years for researchers at Mercator Genetics to effectively identify and clone the ... This gene is closely linked to the HLA-A3 locus.[citation needed] Since the regulation of iron metabolism is still poorly ... collaborators confirmed that haemochromatosis is an autosomal recessive disorder that has a link to the human leukocyte antigen ...
HLA class II histocompatibility antigen gamma chain also known as HLA-DR antigens-associated invariant chain or CD74 (Cluster ... Schulze MS, Wucherpfennig KW (February 2012). "The mechanism of HLA-DM induced peptide exchange in the MHC class II antigen ... Riberdy JM, Newcomb JR, Surman MJ, Barbosa JA, Cresswell P (December 1992). "HLA-DR molecules from an antigen-processing mutant ... "Membrane insertion and oligomeric assembly of HLA-DR histocompatibility antigens" (PDF). Cell. 29 (1): 61-69. doi:10.1016/0092- ...
HLA (formerly known as Tissue Antigens) is a peer-reviewed scientific journal established in 1971. It covers research on ... In 2016 in changed its name from Tissue Antigens to HLA. Official website v t e (Articles with short description, Short ...
... have reduced expression of HLA-DR antigens, causing immunosuppression. In addition, nicotine impairs the ... and HLA-DR antigen expression in smokers and nonsmokers". Cancer Detection and Prevention. 19 (3): 268-273. ISSN 0361-090X. ... Zmijewski, Jaroslaw W.; Pittet, Jean-Francois (October 2020). "Human Leukocyte Antigen-DR Deficiency and Immunosuppression- ...
During tissue typing, an individual's human leukocyte antigens (HLA) are identified. HLA molecules are presented on the surface ... including HLA Class I A, B, and C genes, as well as HLA Class II DRB1, DRB3, DRB4, DRB5, DQA1, DQB1, DPA1, and DPB1 genes. HLA ... If HLA from the donor is recognized by the recipient's immune system as different from the recipient's own HLA, an immune ... More specifically, HLA mismatches between organ donors and recipients can lead to the development of anti-HLA donor-specific ...
Among immune-related refractoriness, antibodies against HLA antigens are the primary cause. Non-immune causes include ... testing for HLA antibodies). If an immune cause is suspected and HLA antibodies are detected, then HLA-selected platelet ... HLA and HPA-selected components should not be used if no HLA or HPA antibodies are detected. Colman, Robert W.; Marder, Victor ... platelet refractoriness Pathogen-reduced platelet component Alloantibodies to platelet antigens Human leucocyte antigen (HLA) ...
Krangel MS, Orr HT, Strominger JL (December 1979). "Assembly and maturation of HLA-A and HLA-B antigens in vivo". Cell. 18 (4 ... Wang Z, Cao Y, Albino AP, Zeff RA, Houghton A, Ferrone S (February 1993). "Lack of HLA class I antigen expression by melanoma ... Saper MA, Bjorkman PJ, Wiley DC (May 1991). "Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 A ... The affinity of different H-2 and HLA antigens for beta-2-microglobulin". Journal of Immunology. 140 (7): 2322-9. doi:10.4049/ ...