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*  HIV vaccine
Most initial approaches have focused on the HIV envelope protein. At least thirteen different gp120 and gp160 envelope ... The trial uses the ALVAC-HIV vaccine and a two-component gp120 protein subunit vaccine with an adjuvant. The trial aims to ... Federal Domestic HIV/AIDS Resource HIVtest.org - Find an HIV testing site near you Potential HIV vaccine using adenoviridae ... Biosantech has developed a novel vaccine called Tat Oyi, which aims at the tat protein. It is reported that the company's HIV ...
*  CCR5 receptor antagonist
Viral entry to the CD4+ cell begins with attachment of the R5 HIV-1 glycoprotein 120 (gp120) to the CD4+ T-cell receptor, which ... As mentioned, the CCR5 receptor is a G-protein coupled receptor (GPCR). Before the discovery of CCR5's role in HIV infection, ... mediated fusion of the viral envelope with the cell membrane and the nucleocapsid enters the host cell (Figure 1). CCR5 co- ... They play an important role as co-receptors that HIV type 1 (HIV-1) uses to attach to cells before viral fusion and entry into ...
*  Oligopeptide
Octapeptide sharing sequence homology with HIV envelope protein gp120. It may be useful as antiviral agent in AIDS therapy. The ... is the HIV envelope sequence required for attachment to the CD4 receptor. Phalloidin - A very toxic polypeptide isolated mainly ... It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein ... They are potent inhibitors of RNA polymerases in most eukaryotic species, the prevent the production of mRNA and protein ...
*  Vasoactive intestinal peptide
"Learning impairment following intracerebral administration of the HIV envelope protein gp120 or a VIP antagonist". Brain ... VIP is a peptide of 28 amino acid residues that belongs to a glucagon/secretin superfamily, the ligand of class II G protein- ...
*  Major histocompatibility complex, class II, DQ alpha 1
1988). "Inhibition of CD4+ T cell function by the HIV envelope protein, gp120". J. Immunol. 141 (11): 3715-7. PMID 2846691. ... The protein encoded by this gene is one of two proteins that are required to form the DQ heterodimer, a cell surface receptor ... Rosenstein Y, Burakoff SJ, Herrmann SH (1990). "HIV-gp120 can block CD4-class II MHC-mediated adhesion". J. Immunol. 144 (2): ... 1991). "Interaction of CD4 with HLA class II antigens and HIV gp120". Immunogenetics. 34 (2): 121-8. doi:10.1007/BF00211424. ...
*  HLA-DPB1
1988). "Inhibition of CD4+ T cell function by the HIV envelope protein, gp120". J. Immunol. 141 (11): 3715-7. PMID 2846691. ... Rosenstein Y, Burakoff SJ, Herrmann SH (1990). "HIV-gp120 can block CD4-class II MHC-mediated adhesion". J. Immunol. 144 (2): ... 1991). "Interaction of CD4 with HLA class II antigens and HIV gp120". Immunogenetics. 34 (2): 121-8. doi:10.1007/BF00211424. ... "Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding". Nature. 339 (6225): 548-51. doi: ...
*  HLA-DOB
1988). "Inhibition of CD4+ T cell function by the HIV envelope protein, gp120". J. Immunol. 141 (11): 3715-7. PMID 2846691. ... 1993). "HIV-1 envelope protein is expressed on the surface of infected cells before its processing and presentation to class II ... 1994). "HLA class II antigens and the HIV envelope glycoprotein gp120 bind to the same face of CD4". J. Immunol. 152 (9): 4475- ... Rowell JF, Stanhope PE, Siliciano RF (1995). "Endocytosis of endogenously synthesized HIV-1 envelope protein. Mechanism and ...
*  HLA-DR
1988). "Inhibition of CD4+ T cell function by the HIV envelope protein, gp120". J. Immunol. 141 (11): 3715-7. PMID 2846691. ... HIV Res. 2 (2): 141-51. doi:10.2174/1570162043484924. PMID 15078178. Anderson JL, Hope TJ (2005). "HIV accessory proteins and ... 1991). "The HIV core protein p24 inhibits interferon-gamma-induced increase of HLA-DR and cytochrome b heavy chain mRNA levels ... 2006). "Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions". Cell Res. 15 (11-12): 923-34. ...
*  HLA-DQA2
1988). "Inhibition of CD4+ T cell function by the HIV envelope protein, gp120". J. Immunol. 141 (11): 3715-7. PMID 2846691. ... 1994). "HLA class II antigens and the HIV envelope glycoprotein gp120 bind to the same face of CD4". J. Immunol. 152 (9): 4475- ... Rowell JF, Stanhope PE, Siliciano RF (1995). "Endocytosis of endogenously synthesized HIV-1 envelope protein. Mechanism and ... 1994). "HIV-1 gp41 binding proteins and antibodies to gp41 could inhibit enhancement of human Raji cell MHC class I and II ...
*  HLA-DRB3 (gene)
1988). "Inhibition of CD4+ T cell function by the HIV envelope protein, gp120". J. Immunol. 141 (11): 3715-7. PMID 2846691. ... 1991). "The HIV core protein p24 inhibits interferon-gamma-induced increase of HLA-DR and cytochrome b heavy chain mRNA levels ... Rosenstein Y, Burakoff SJ, Herrmann SH (1990). "HIV-gp120 can block CD4-class II MHC-mediated adhesion". J. Immunol. 144 (2): ... 1990). "Genetic variability in HIV-1 gp120 affects interactions with HLA molecules and T cell receptor". J. Immunol. 144 (9): ...
*  GRIN2D
Wu P, Price P, Du B, Hatch WC, Terwilliger EF (1996). "Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons ... Lannuzel A, Lledo PM, Lamghitnia HO, Vincent JD, Tardieu M (1995). "HIV-1 envelope proteins gp120 and gp160 potentiate NMDA- ... Dreyer EB, Lipton SA (1995). "The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via ... Raber J, Toggas SM, Lee S, Bloom FE, Epstein CJ, Mucke L (1996). "Central nervous system expression of HIV-1 Gp120 activates ...
*  GRIN2B
Wu P, Price P, Du B, Hatch WC, Terwilliger EF (April 1996). "Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT ... Lannuzel A, Lledo PM, Lamghitnia HO, Vincent JD, Tardieu M (November 1995). "HIV-1 envelope proteins gp120 and gp160 potentiate ... Dreyer EB, Lipton SA (December 1995). "The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via ... Schröder HC, Perovic S, Kavsan V, Ushijima H, Müller WE (1998). "Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell ...
*  FCGRT
Dürrbaum-Landmann I, Kaltenhäuser E, Flad HD, Ernst M (1994). "HIV-1 envelope protein gp120 affects phenotype and function of ... IgG receptor FcRn large subunit p51 is a protein that in humans is encoded by the FCGRT gene. FCGRT has been shown to interact ...
*  FCAR
Dürrbaum-Landmann I, Kaltenhäuser E, Flad HD, Ernst M (April 1994). "HIV-1 envelope protein gp120 affects phenotype and ... CD89 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from ... Gulle H, Samstag A, Eibl MM, Wolf HM (January 1998). "Physical and functional association of Fc alpha R with protein tyrosine ... the protein's primary structure is similar to receptors in the leukocyte receptor cluster (LRC), and the FCAR gene appears ...
*  Peptide T
... is a short peptide derived from the HIV envelope protein gp120 which blocks binding and infection of viral strains which use ... HIV Res. 1 (1): 51-67. doi:10.2174/1570162033352066. PMID 15043212. Heseltine PN, Goodkin K, Atkinson JH, et al. (Jan 1998). " ... Peptide T has several positive effects related to HIV disease and Neuro-AIDS. A FDG-PET neuro-imaging study in an individual ... Peptide T is an HIV entry inhibitor discovered in 1986 by researchers at the National Institutes of Health in the United States ...
*  Susan Zolla-Pazner
... of the HIV envelope protein gp120, as observed in the Phase 3 RV144 clinical HIV vaccine trial, which involved 16,402 ... "Peptides Mimicking HIV-1 Viral Epitopes in the V2 Loop for the Gp120 Surface Envelope Glycoprotein" (American Inventors)". ... "Cross-clade HIV-1 neutralizing antibodies induced with V3-scaffold protein immunogens following priming with gp120 DNA". ... Pan, R; Gorny, MK; Zolla-Pazner, S; Kong, X-P (2015-08-01). "The V1V2 Region of HIV-1 gp120 Forms a Five-Stranded Beta Barrel ...
*  Moesin
"Specific binding of HIV-1 envelope protein gp120 to the structural membrane proteins ezrin and moesin". Virus Res. 49 (2): 215- ... Moesin is a protein that in humans is encoded by the MSN gene. Moesin (for membrane-organizing extension spike protein) is a ... Matarrese P, Malorni W (2005). "Human immunodeficiency virus (HIV)-1 proteins and cytoskeleton: partners in viral life and host ... a member of the protein 4.1-talin-ezrin family of proteins". Proc. Natl. Acad. Sci. U.S.A. 88 (19): 8297-301. doi:10.1073/pnas. ...
*  GRIN3B
1996). "HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce ... 1996). "Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons". NeuroReport. 7 (5): 1045-9. doi:10.1097/ ... Dreyer EB, Lipton SA (1996). "The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via ... Toggas SM, Masliah E, Mucke L (1996). "Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of ...
*  GRIN1
1996). "HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce ... brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120". ... 1996). "Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and ... 1998). "Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death". Neurotoxicology. 19 (4-5): 683-8. PMID 9745929. ...
*  RV 144
... but those in the study who produced IgG antibodies that recognise the V2 loop in the HIV envelope protein gp120 were 43% less ... "HIV gp120 vaccine - VaxGen: AIDSVAX, AIDSVAX B/B, AIDSVAX B/E, HIV gp120 vaccine - Genentech, HIV gp120 vaccine AIDSVAX - ... AIDSVAX B/E is composed of genetically engineered gp120, a protein on the surface of HIV. RV 144 is sponsored by the Surgeon ... "Safety and Reactogenicity of Canarypox ALVAC-HIV (vCP1521) and HIV-1 gp120 AIDSVAX B/E Vaccination in an Efficacy Trial in ...
*  BanLec
Researchers at the University of Michigan determined that BanLec bound to the HIV-1 envelope protein gp120, which is high in ... "Study: Chemical in Bananas Could Help Fight HIV", Fox News Channel, March 16, 2010 "Protein in bananas could help block spread ... The protein is highly stable, unfolding only at high temperatures All jacalin-related lectins feature type I beta-prism folding ... BanLec is one of the predominant proteins in the pulp of ripe bananas and has binding specificity for mannose and mannose- ...
*  Raghavan Varadarajan
"Glycosylation of the core of the HIV-1 envelope subunit protein gp120 is not required for native trimer formation or viral ... "HIV-1 Envelope Based Fragments". Patents Encyclopedia. 2016. Retrieved October 19, 2016. "Summary of Achievements" (PDF). ... He is known for his researches in the fields of protein structure and protein folding and his contributions in developing ... Varadarajan's early researches were focused on the interaction of protein molecules and their sequential properties. At Steven ...
*  Somatostatin
Barnea A, Roberts J, Ho RH (January 1999). "Evidence for a synergistic effect of the HIV-1 envelope protein gp120 and brain- ... In the stomach, somatostatin acts directly on the acid-producing parietal cells via a G-protein coupled receptor (which ... a protein coupled to adenylyl cyclase". Molecular Endocrinology. 6 (12): 2136-42. doi:10.1210/me.6.12.2136. PMID 1337145. ... hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein ...
*  Neutralizing domain
... most commonly on the envelope protein gp120) that elicits antibodies with neutralizing activity. V3 loop Human Immunodeficiency ... "HIV Vaccine Glossary". NIAID Fact Sheet. AIDSinfo. Retrieved 2009-08-10. Neutralizing domain in the external envelope ... NLM Gateway Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein, PNAS. ... The neutralizing domain is a specific site or section of the Human Immunodeficiency Virus(HIV) ( ...
*  CCR5
... have been designed to interfere with the associative binding between the Gp120 envelope protein and the HIV co-receptor CCR5. ... During HIV-1 infection, the Gp120 envelope glycoprotein subunit binds to a CD4 glycoprotein and a HIV-1 co-receptor expressed ... The Gp120 envelope protein is a chemokine mimic. It lacks the unique structure of a chemokine, however it is still capable of ... The HIV-1 envelope glycoprotein structure is essential in enabling the viral entry of HIV-1 into a target host cell. The ...
*  GANC
Murphy CI, Lennick M, Lehar SM, Beltz GA, Young E (Oct 1990). "Temporal expression of HIV-1 envelope proteins in baculovirus- ... native gp120 and gp160 of the human immunodeficiency virus type 1". AIDS Research and Human Retroviruses. 6 (3): 371-80. doi: ... "Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein". Journal of Acquired Immune ... Gruters RA, Neefjes JJ, Tersmette M, de Goede RE, Tulp A, Huisman HG, Miedema F, Ploegh HL (1987). "Interference with HIV- ...
*  PRKACG
1998). "Effects of [D-Ala1] peptide T-NH2 and HIV envelope glycoprotein gp120 on cyclic AMP dependent protein kinases in normal ... 2004). "HIV-1 gp120 induces anergy in naive T lymphocytes through CD4-independent protein kinase-A-mediated signaling". J. ... "The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological ... 1994). "HIV Gag p17 protein impairs proliferation of normal lymphocytes in vitro". AIDS. 8 (7): 1016-7. doi:10.1097/00002030- ...