The hepatitis delta virus (HDV) ribozyme is a non-coding RNA found in the hepatitis delta virus that is necessary for viral ... Modahl LE, Lai MM (July 1998). "Transcription of hepatitis delta antigen mRNA continues throughout hepatitis delta virus (HDV) ... Page for Hepatitis delta virus ribozyme at Rfam Subviral RNA database entry for HDV ribozyme (Articles to be expanded from May ... In the hepatitis delta virus, this substrate nucleotide sequence begins with uridine and is known as U(-1), however, the ...

The hepatitis delta virus ribozyme is a well known example of a catalytic RNA with a pseudoknot in its active site. Though DNA ... Lai, Michael M. C. (1995-06-01). "The Molecular Biology of Hepatitis Delta Virus". Annual Review of Biochemistry. 64 (1): 259- ... Doudna, Jennifer A.; Ferré-D'Amaré, Adrian R.; Zhou, Kaihong (October 1998). "Crystal structure of a hepatitis delta virus ...

They called it "Hepatitis Delta Virus" (HDV). This new virus was found to be defective. HDV needed HBV to act as a helper ... Incubation of Hepatitis D typically lasts for thirty five days. Most often Hepatitis D is a co-infection with Hepatitis B or a ... HDV is still considered an unusual form of hepatitis. Agents of this virus resemble that of plant viroids. It is still hard to ... Normally Hepatitis B is transmitted through blood or any type of blood product. In South America Hepatitis D was found to be ...

Ferré-D'Amaré AR, Zhou K, Doudna JA (October 1998). "Crystal structure of a hepatitis delta virus ribozyme". Nature. 395 (6702 ...

One example of a pseudoknot motif is the highly stable Hepatitis Delta virus ribozyme, in which the backbone shows an overall ... Ferré-D'Amaré AR, Zhou K, Doudna JA (October 1998). "Crystal structure of a hepatitis delta virus ribozyme". Nature. 395 (6702 ... Prody GA, Bakos JT, Buzayan JM, Schneider IR, Bruening G (March 1986). "Autolytic Processing of Dimeric Plant Virus Satellite ...

Zheng H, Fu TB, Lazinski D, Taylor J (August 1992). "Editing on the genomic RNA of human hepatitis delta virus". Journal of ... Viruses (i.e., measles, mumps, or parainfluenza), especially viruses that have an RNA genome, have been shown to have evolved ... Viruses are known to utilize the RNA modifications in different parts of their infection cycle from immune evasion to protein ... Curran J, Boeck R, Kolakofsky D (October 1991). "The Sendai virus P gene expresses both an essential protein and an inhibitor ...

MYR focuses on the treatment of chronic hepatitis delta virus. On August 11, 2021, U.S. Senator Rand Paul disclosed that his ... In 2013, the FDA approved this drug, under the trade name Sovaldi, as a treatment for the hepatitis C virus. Forbes magazine ... This transaction helped cement Gilead as the leader in treatment of the hepatitis C virus by giving it control of sofosbuvir ( ... hepatitis B, hepatitis C, influenza, and COVID-19, including ledipasvir/sofosbuvir and sofosbuvir. Gilead is a member of the ...

Hepatitis D is caused by the hepatitis D virus (HDV), or hepatitis delta virus; it belongs to the genus Deltavirus. HDV is ... Hepatitis F virus (HFV) is a hypothetical virus linked to certain cases of hepatitis. Several hepatitis F virus candidates ... Junín virus, Lassa fever virus, Lujo virus, Machupo virus, and Sabiá virus Bunyaviruses: Crimean-Congo hemorrhagic fever virus ... Hepatitis C (originally "non-A non-B hepatitis") is caused by hepatitis C virus (HCV), an RNA virus of the family Flaviviridae ...

"Hepatitis delta virus infection in a large cohort of chronic hepatitis B patients in Ethiopia". Liver Int. 38 (6): 1000-1009. ... "Clade homogeneity and low rate of delta virus despite hyperendemicity of hepatitis B virus in Ethiopia". Virol. J. 14 (1): 176 ... "Prevalence of hepatitis D virus infection among hepatitis B virus-infected individuals in India". Indian J Gastroenterol. 34 (2 ... Alfaiate, Dulce; Dény, Paul; Durantel, David (2015). "Hepatitis delta virus: From biological and medical aspects to current and ...

... is a type of viral hepatitis caused by the hepatitis delta virus (HDV). HDV is one of five known hepatitis viruses ... November 2009). "Hepatitis B virus and hepatitis delta virus genotypes in outbreaks of fulminant hepatitis (Labrea black fever ... Taylor JM (2006). "Structure and replication of hepatitis delta virus RNA". Hepatitis Delta Virus. Current Topics in ... World Health Organization Fact sheet on Hepatitis D ICTV Report: Deltavirus Viralzone: Deltavirus "Hepatitis delta virus". NCBI ...

Her group has crystallized other ribozymes, including the Hepatitis Delta Virus ribozyme. This initial work to solve large RNA ... In addition to the CRISPR breakthrough, Doudna has discovered that the hepatitis C virus utilizes an unusual strategy to ... The protein attacks its prey, the DNA of viruses, and slices it up, preventing it from infecting the bacterium. This system was ...

"Hepatitis delta virus-like circular RNAs from diverse metazoans encode conserved hammerhead ribozymes". Virus Evolution. 7 (1 ... In 2021, novel Hepatitis D virus genomes of circular RNA from diverse animals were found to encode hammerhead ribozymes similar ... A massive bioinformatic search of deltavirus-like agents around the globe has uncovered hundreds of examples of circular RNA ... Prody GA, Bakos JT, Buzayan JM, Schneider IR, Bruening G (1986). "Autolytic Processing of Dimeric Plant Virus Satellite RNA". ...

... which contains hepatitis delta-like viruses with circular, negative-sense ssRNA genomes; and Varidnaviria, which contains all ... and the rabies virus, as well as the first virus to be discovered, Tobacco mosaic virus. Reverse transcribing viruses are a ... "Virus Taxonomy: 2019 Release". International Committee on Taxonomy of Viruses. International Committee on Taxonomy of Viruses. ... Riboviria mostly contains eukaryotic viruses, and most eukaryotic viruses, including most human, animal, and plant viruses, ...

The CPEB3 ribozyme is structurally and biochemically related to the human hepatitis delta virus ribozyme. Other HDV-like ...

Liao FT, Lee YJ, Ko JL, Tsai CC, Tseng CJ, Sheu GT (May 2009). "Hepatitis delta virus epigenetically enhances clusterin ... CLU activity is also involved in infectious diseases, such as hepatitis C. CLU is induced by the stress of hepatitis C viral ... stabilizes core and NS5A to promote infectious hepatitis C virus virion production". Journal of Hepatology. 61 (5): 984-93. doi ... The chaperone protein then aids hepatitis C viral assembly by stabilizing its core and NS5A units. CLU expression in the kidney ...

Folding of other ribozymes (hepatitis delta virus, ribonuclease P, hairpin ribozyme) has also been proposed. Several years ...

2005). "Novel nuclear export signal-interacting protein, NESI, critical for the assembly of hepatitis delta virus". J. Virol. ...

... influenza virus, lymphocytic choriomeningitis virus, polyomavirus, hepatitis delta virus, and hepatitis C virus. Although ADAR1 ... "A specific base transition occurs on replicating hepatitis delta virus RNA". Journal of Virology. 64 (3): 1021-1027. doi: ... Taylor DR, Puig M, Darnell ME, Mihalik K, Feinstone SM (May 2005). "New antiviral pathway that mediates hepatitis C virus ... ADAR1's A to I editing has been found in many viruses including measles virus, ...

Alves, Carolina; Branco, Cristina; Cunha, Celso (2013). "Hepatitis Delta Virus: A Peculiar Virus". Advances in Virology. 2013: ... and supported by a helper virus (Hepatitis B virus) to form virions; however, the virions possess a much larger genome size (~ ... Satellite Tobacco Mosaic Virus (STMV) was the first subviral agent to be developed as a satellite virus-induced silencing ... Virusoids, while being studied in virology, are subviral particles rather than viruses. Since they depend on helper viruses, ...

... hepatitis delta virus, group I, group II, and RNase P ribozymes. Hammerhead, hairpin, and hepatitis delta virus (HDV) ribozyme ... In hepatitis B, siRNA silencing was used to target the surface antigen on the hepatitis B virus and led to a decrease in the ... Randall G, Rice CM (June 2004). "Interfering with hepatitis C virus RNA replication". Virus Research. 102 (1): 19-25. doi: ... Gene silencing techniques have also been used to target other viruses, such as the human papilloma virus, the West Nile virus, ...

Examples of such ribozymes include the hammerhead ribozyme, the Hepatitis Delta Virus (HDV) ribozyme, and the hairpin ribozyme ...

Jayan GC, Casey JL (April 2002). "Increased RNA editing and inhibition of hepatitis delta virus replication by high-level ... Jayan GC, Casey JL (December 2002). "Inhibition of hepatitis delta virus RNA editing by short inhibitory RNA-mediated knockdown ...

... human hepatitis delta virus 4 (HDV-4)] (host: H. sapiens) Species: Deltavirus togense [human hepatitis delta virus 5 (HDV-5)] ( ... human hepatitis delta virus 7 (HDV-7)] (host: Homo sapiens) Species: Deltavirus carense [human hepatitis delta virus 6 (HDV-6 ... human hepatitis delta virus 1 (HDV-1)] (host: H. sapiens) Species: Deltavirus japanense [human hepatitis delta virus 2 (HDV-2 ... human hepatitis delta virus 3 (HDV-3)] (host: H. sapiens) Species: Deltavirus senegalense [human hepatitis delta virus 8 (HDV-8 ...

Dora and her team was able identify a new subgenotype of hepatitis b virus (a3), hepatitis delta and c strains. they also ... Screening for hepatitis C virus infection in a high prevalence country by an antigen/antibody combination assay versus a rapid ... "Screening for hepatitis C virus infection in a high prevalence country by an antigen/antibody combination assay versus a rapid ... like hepatitis B, C, Syphilis, and HIV. ...

Epstein-Barr virus (EBV), human immunodeficiency virus (HIV), hepatitis delta virus (HDV) and hepatitis C virus (HCV). Some ... such as Epstein-Barr virus (EBV), human T-lymphotropic virus 1, and hepatitis C virus, their association with Sjögren's ... Epstein-Barr virus, hepatitis C, and human T-cell leukemia virus-1 are among the most studied infectious agents in Sjögren's ... "Hepatitis Delta Virus Detected in Salivary Glands of Sjögren's Syndrome Patients and Recapitulates a Sjögren's Syndrome-Like ...

Delta-interacting protein A (DIPA), a cellular gene product, has been found to have homology to hepatitis delta virus antigen ( ... Hepatitis delta virus (HDV) is a pathogenic human virus whose RNA genome and replication cycle resemble those of plant viroids ... Long M, de Souza SJ, Gilbert W (May 1997). "Delta-interacting protein A and the origin of hepatitis delta antigen". Science. ... Brazas R, Ganem D (Oct 1996). "A cellular homolog of hepatitis delta antigen: implications for viral replication and evolution ...

... through which the hepatitis delta and hepatitis B viruses enter liver cells. By blocking the entry of the virus into the cells ... The drug is also effective against hepatitis D because the hepatitis D virus uses the same entry receptor as HBV and is only ... Bulevirtide is indicated for the treatment of chronic hepatitis delta virus (HDV) infection in plasma (or serum) HDV-RNA ... The hepatitis B virus uses its surface lipopeptide pre-S1 for docking to mature liver cells via their sodium/bile acid ...

... delta/anti-delta) associated to hepatitis B virus in liver and in serum of HBsAg carriers". Gut. 18 (12): 997-1003. doi:10.1136 ... Mario Rizzetto (born 4 June 1945) is an Italian virologist who in 1977 first reported the Hepatitis D virus as a nuclear ...

For example, pancreatic ribonuclease A and hepatitis delta virus (HDV) ribozymes can catalyze the cleavage of RNA backbone ... Lieber A, He CY, Polyak SJ, Gretch DR, Barr D, Kay MA (December 1996). "Elimination of hepatitis C virus RNA in infected human ... Similarly, ribozymes have been designed to target the hepatitis C virus RNA, SARS coronavirus (SARS-CoV), Adenovirus and ... The ribozyme is able to cleave the conserved regions of the virus's genome, which has been shown to reduce the virus in ...

The ribozyme for the hepatitis delta virus (HDV) folds into a double-pseudoknot structure and self-cleaves its circular genome ... Pseudoknots also play a role in programmed ribosomal frameshifting found in some viruses and required in the replication of ... and eukaryotic viruses to mammalian cells. The replication origins of the phage G4 and other related phages comprise a segment ...

Alves C, Branco C, Cunha C (2013). "Hepatitis delta virus: a peculiar virus". Advances in Virology. 2013: 560105. doi:10.1155/ ... The human pathogen hepatitis D virus is a subviral agent similar in structure to a viroid. As of 2005[update]: Family ... 2012). Virus Taxonomy. Ninth Report of the International Committee for Virus Taxonomy. Burlington, Massachusetts, US: Elsevier ... Circular RNA Microparasite Non-cellular life Plant pathology Plasmid Prion RNA world hypothesis Satellite (biology) Virus Virus ...