... (core antigen) is a hepatitis B viral protein. It is an indicator of active viral replication; this means the person ... May 2003). "New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and relation between levels of HBcAg ... HBcAg is an antigen that can be found on the surface of the nucleocapsid core (the inner most layer of the hepatitis B virus). ... "In vivo inhibition of anti-hepatitis B virus core antigen (HBcAg) immunoglobulin G production by HBcAg-specific CD4(+) Th1-type ...
... encoding the core antigen and pre-core protein which are processed and secreted as DHBcAg S-ORF - codes for the surface antigen ... is composed of the virus core antigen (DHBcAg) and surrounds the DNA genome and viral polymerase. The viral genome is a ... Duck hepatitis B virus, abbreviated DHBV, is part of the genus Avihepadnavirus of the Hepadnaviridae, and is the causal agent ... Cooper A, Paran N, Shaul Y (2003-07-11). "The earliest steps in hepatitis B virus infection". Biochimica et Biophysica Acta ( ...
The product of the X gene is hepatitis B x antigen (HBxAg). It may be involved in carcinogenesis. Basal core promoter mutants ... A precore mutant is a variety of hepatitis B virus that does not produce hepatitis B virus e antigen (HBeAg). These mutants are ... core promoter mutants limits the probability of response to peginterferon in hepatitis B e antigen-positive chronic hepatitis B ... They are readily detectable by HBV DNA in serum, but hepatitis B e antigen (HBeAg) is absent. The X gene codes for HBxAg. ...
HBcAg (hepatitis B core antigen) is the main structural protein of HBV icosahedral nucleocapsid and it has function in ... Co-infection of hepatitis B and various other viruses can also occur. hepatitis C, hepatitis D (a satellite virus of hepatitis ... HBeAg (hepatitis B envelope antigen) can be found between the icosahedral nucleocapsid core and the lipid envelope, but is ... May 2010). "Hepatitis B virus core antigen determines viral persistence in a C57BL/6 mouse model". Proceedings of the National ...
The icosahedral core particle is made of 180 or 240 copies of the core protein, alternatively known as hepatitis B core antigen ... "Predictive factors for reactivation of hepatitis B following hepatitis B e antigen seroconversion in chronic hepatitis B". ... Hepatitis D (HDV) can occur only with a concomitant hepatitis B infection, because HDV uses the HBV surface antigen to form a ... the HBsAg will become undetectable and will be followed by IgG antibodies to the hepatitis B surface antigen and core antigen ( ...
... after genetic immunization with retroviral vectors expressing different forms of the hepatitis B virus core and e antigens". ... The antigen-presenting cell then travels to the lymph nodes and presents the antigen peptide and costimulatory molecule ... This is true for intracellular and plasma membrane-bound antigens, but not for secreted antigens, which seem to generate TH2 ... Secreted or plasma membrane-bound antigens are more effective at inducing antibody responses than cytosolic antigens, while ...
... is an antigen that can be found between the icosahedral nucleocapsid core and the lipid envelope (the outer most layer of ... HBeAg is a hepatitis B viral protein, produced by the HBcAg reading frame. It is an indicator of active viral replication; this ... The presence of HBeAg in the serum of patients can serve as a marker of active replication in chronic hepatitis. Although the ... page 2062 (Articles with short description, Short description matches Wikidata, Viral structural proteins, Hepatitis B virus). ...
Method for Reentry of Blood Donors Deferred Because of Reactive Test Results for Antibody to Hepatitis B Core Antigen (Anti-HBc ... Hepatitis B virus (HBV), and hepatitis C virus (HCV) and are permanently prohibited from donating plasma. NDDR is a registered ...
... hepatitis B surface antibody for IgM and IgG, hepatitis B core antibody for IgM and IgG, and hepatitis B e-antigen. In the ... "Predictive factors for reactivation of hepatitis B following hepatitis B e antigen seroconversion in chronic hepatitis B". ... assays for HBV also test for antigens. The standard serology panel for seroconversion include hepatitis B surface antigen, ... the presence of hepatitis B surface antigen (HBsAg) indicates an individual with a currently active hepatitis B infection, ...
"Intramembrane processing by signal peptide peptidase regulates the membrane localization of hepatitis C virus core protein and ... In mice, a nonamer peptide originating from the SPP protein serves as minor histocompatibility antigen HM13 that plays a role ... SPP also plays a pathophysiological role; it cleaves the structural nucleocapsid protein (also known as core protein) of the ... Hepatitis C virus and thus influences viral reproduction rate. ...
... such as the hepatitis B surface or core antigen), anti-viral antibodies (such as the anti-hepatitis B surface antibody or anti- ... Viral hepatitis is caused by five different viruses (hepatitis A, B, C, D, and E). Hepatitis A and hepatitis E behave similarly ... In the Mediterranean, hepatitis D is predominant among hepatitis B virus co-infected people. Similar to Hepatitis A, hepatitis ... and are self-limiting illnesses that do not lead to chronic hepatitis. Hepatitis B, hepatitis C, and hepatitis D are ...
McLauchlan J, Lemberg MK, Hope G, Martoglio B (2002). "Intramembrane proteolysis promotes trafficking of hepatitis C virus core ... The minor histocompatibility antigen 13 is a nonamer peptide that originates from a protein encoded by the H13 gene. The ... and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs ... Minor histocompatibility antigen H13 is a protein that in humans is encoded by the HM13 gene. ...
"Phase IIII Study of a Therapeutic Vaccine Candidate Containing Hepatitis B Virus (HBV) Core Antigen (HBcAg) and HBV Surface ... He is member of Asian Pacific Association for the Study of the Liver (APASL) Working Parties on hepatitis B, hepatitis C, acute ... "Treatment of chronic hepatitis B naïve patients with a therapeutic vaccine containing HBs and HBc antigens (a randomized, open ... "Treatment of chronic hepatitis B naïve patients with a therapeutic vaccine containing HBs and HBc antigens (a randomized, open ...
... is a spherical, enveloped virus. The core particle, or nucleocapsid, contains e antigen, viral ... Feitelson, M A; Marion, P L; Robinson, W S (August 1982). "Core particles of hepatitis B virus and ground squirrel hepatitis ... Two are for the genes encoding the structural proteins (surface antigens and core antigens), and the other two are unassigned. ... The virus particles contain two major structural proteins, surface antigens (sAg) and core antigens (cAg). Both proteins were ...
... of Chronic Hepatitis B and Anti-HBs Seroconversion in Man by Adoptive Transfer of Immunity to Hepatitis B core Antigen. ... Hepatitis due to Reactivation of Hepatitis B Virus in Endemic Areas Among Patients With Hepatitis C Treated With Direct-acting ... The study indicated that there may be an increased risk of hepatitis B reactivation for patients with concurrent hepatitis C ... Hepatitis Research Foundation joined hands to hold a "Hepatitis-free Generation" event week at the end of November 2003. The ...
... core antigen of hepatitis B Bunyaviridae nonstructural S proteins Viral structural protein Viral+Nonstructural+Proteins at the ...
Lok, AS (2007). "Chronic Hepatitis B" (PDF). Hepatology. 45 (2): 507-39. doi:10.1002/hep.21513. hdl:2027.42/55941. PMID ... During the window of HBsAg to HBsAb seroconversion, IgM anti-core (HBc-IgM) is the only detectable antibody. HBV DNA may be ... between the disappearance of surface antigen (HBsAg) from serum and the appearance of HBsAb (anti-HBs), and (2) the period ... This window period does not occur in persons who develop chronic hepatitis B, i.e. who continue to have detectable HBV DNA for ...
Hepatitis B surface antigen Antibody to hepatitis C Antibody to HIV, usually subtypes 1 and 2 Serologic test for syphilis The ... Donated blood is tested by many methods, but the core tests recommended by the World Health Organization are these four: ... For example, the HIV antibody test will not detect a recently infected donor, so some blood banks use a p24 antigen or HIV ... The screening includes testing for diseases that can be transmitted by a blood transfusion, including HIV and viral hepatitis. ...
... hepatitis B surface antigen, anti-hepatitis B core, and anti-hepatitis B surface). A person who has never been exposed to ... When a person gets a hepatitis B vaccine then the most common test for hepatitis B will show them to be positive. The usual ... "WHO , Hepatitis B". who.int. World Health Organization. 2011. Retrieved 7 July 2011. See the table "HBV serological markers in ... hepatitis B but has gotten the vaccine will be positive for anti-HBs but negative for the other two tests in the panel. Other ...
Mamiya N, Worman HJ (May 1999). "Hepatitis C virus core protein binds to a DEAD box RNA helicase". The Journal of Biological ... "An N-acetylated natural ligand of human histocompatibility leukocyte antigen (HLA)-B39. Classical major histocompatibility ... This gene encodes a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in ... Owsianka AM, Patel AH (May 1999). "Hepatitis C virus core protein interacts with a human DEAD box protein DDX3". Virology. 257 ...
Persistence of hepatitis B and hepatitis C viral genomes in primary liver cancers from hepatitis B surface antigen-negative ... Hepatitis C Virus core protein-induced apoptosis is triggered by ER stress and deregulation of calcium signaling, Oncogene, 31 ... Bréchot C, Minami M, De Mitri S, Paterlini P. Hepatitis B and C viruses in Hepatitis B Surface antigen negative hepatocellular ... Paterlini P. and Bréchot C., Hepatitis B Virus and Primary Livcer Cancer in Hepatitis B Surface Antigen-Positive and -Negative ...
... the external core antigen, protein P (polymerase), and protein x (multifunctional protein). The polymerase open reading frame ( ... Woolly monkey hepatitis B virus, like other hepatitis B viruses, is transmitted through bodily fluids, and from a mother to her ... WMHBV, like other hepatitis viruses, infects the hepatocytes, or liver cells, of its host organism. It can cause hepatitis, ... The core gene of WMHBV was the most similar to human HBV with 85.8-86.9% similarity at the amino acid level, while the WHMBV X ...
The autoimmune target of anti-sp100 is the sp100 nuclear antigen which was identified by its association with primary biliary ... The sera of these patients exhibit a characteristic "nuclear dots" pattern in indirect immunofluorescence (IIF) on Hep-2 cells ... Bolded areas represent the core epitope.) Szostecki C, Guldner HH, Netter HJ, Will H (1990). "Isolation and characterization of ... cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis ...
... there is cross-reactivity between influenza virus-specific CD8+ T cells and hepatitis C virus antigens. Cross reactivity may ... containing core α1,3-linked fucose. As CCDs apparently do not elicit allergic symptoms, a positive in vitro test based on IgE ... In immunology, cross-reactivity has a more narrow meaning of the reaction between an antibody and an antigen that differs from ... There can be cross-reactivity between the immune system and the antigens of two different pathogens, or between one pathogen ...
The risk of hepatitis B (e antigen positive) seroconversion is estimated at 37-62%, significantly more than other blood borne ... HB core IgM, HCV) and for immunized individuals, HB surface antibody. Unless already known, the infectious status of the source ... hepatitis C, and HIV is the highest. The World Health Organization estimated that in 2000, 66,000 hepatitis B, 16,000 hepatitis ... HIV and the hepatitis C virus (HCV) are only viable for hours after blood has dried, but the hepatitis B virus (HBV) is stable ...
VLPs derived from the Hepatitis B virus (HBV) and composed of the small HBV derived surface antigen (HBsAg) were described in ... In addition, wasps produce polydnavirus vectors with pathogenic genes (but not core viral genes) or gene-less VLPs to help ... RTS,S is a portion of the Plasmodium falciparum circumsporozoite protein fused to the Hepatitis B surface antigen (RTS), ... combined with Hepatitis B surface antigen (S), and adjuvanted with AS01 (consisting of (MPL)A and saponin). Vaccine production ...
... the first known hepatitis with a viral etiological agent was Hepatitis A, in the picornaviridae family. Hepatitis B Virus (HBV ... Four main open reading frames are encoded (ORFs) and the virus has four known genes which encode seven proteins: the core ... capsid protein, the viral polymerase, surface antigens-preS1, preS2, and S, the X protein and HBeAg. The X protein is thought ... Its best-known member is hepatitis B virus. Diseases associated with this family include: liver infections, such as hepatitis, ...
... hepatitis a antigens MeSH D23.050.327.495.500 - hepatitis b antigens MeSH D23.050.327.495.500.450 - Hepatitis B core antigens ... Hepatitis B surface antigen MeSH D23.050.327.495.505 - hepatitis c antigens MeSH D23.050.327.495.752 - hepatitis delta antigens ... antigens, cd15 MeSH D23.101.100.900.131 - antigens, cd31 MeSH D23.101.100.920 - antigens, ly MeSH D23.101.100.930 - antigens, ... forssman antigen MeSH D23.050.285.018 - antigens, cd24 MeSH D23.050.285.025 - antigens, cd30 MeSH D23.050.285.040 - antigens, ...
Hepatitis B virus DNA in patients with chronic liver disease and negative tests for hepatitis B surface antigen. N. Engl. J. ... Aug, 54(8):1162-8. Pavio N, Boucreux D, Battaglia S, Arnulf B, Sobesky R, Hermine O, Brechot C. Hepatitis C virus core variants ... Distinct Hepatitis C Virus Core and F protein quasispecies in tumoral and nontumoral hepatocytes. Hepatology 2007 Dec;46(6): ... Hepatitis C virus core protein shows an exclusively cytoplasmic localization and associates to cellular lipid storage droplets ...
The hepatitis delta virus of humans has an RNA genome similar to viroids but has a protein coat derived from hepatitis B virus ... Shuda M, Feng H, Kwun HJ, Rosen ST, Gjoerup O, Moore PS, Chang Y (October 2008). "T antigen mutations are a human tumor- ... Their genomic dsRNA remains protected inside the core of the virion. When the adaptive immune system of a vertebrate encounters ... Although hepatitis delta virus genome may replicate independently once inside a host cell, it requires the help of hepatitis B ...