... (core antigen) is a hepatitis B viral protein. It is an indicator of active viral replication; this means the person ... May 2003). "New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and relation between levels of HBcAg ... HBcAg is an antigen that can be found on the surface of the nucleocapsid core (the inner most layer of the hepatitis B virus). ... "In vivo inhibition of anti-hepatitis B virus core antigen (HBcAg) immunoglobulin G production by HBcAg-specific CD4(+) Th1-type ...
... after genetic immunization with retroviral vectors expressing different forms of the hepatitis B virus core and e antigens". ... The antigen-presenting cell then travels to the lymph nodes and presents the antigen peptide and costimulatory molecule ... This is true for intracellular and plasma membrane-bound antigens, but not for secreted antigens, which seem to generate TH2 ... Secreted or plasma membrane-bound antigens are more effective at inducing antibody responses than cytosolic antigens, while ...
Mamiya N, Worman HJ (May 1999). "Hepatitis C virus core protein binds to a DEAD box RNA helicase". The Journal of Biological ... "An N-acetylated natural ligand of human histocompatibility leukocyte antigen (HLA)-B39. Classical major histocompatibility ... This gene encodes a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in ... Owsianka AM, Patel AH (May 1999). "Hepatitis C virus core protein interacts with a human DEAD box protein DDX3". Virology. 257 ...
... is an antigen that can be found between the icosahedral nucleocapsid core and the lipid envelope (the outer most layer of ... HBeAg is a hepatitis B viral protein. It is an indicator of active viral replication; this means the person infected with ... The presence of HBeAg in the serum of patients can serve as a marker of active replication in chronic hepatitis. Although the ... "ORF Core" and "Pre C" are translated together, the result is HBeAg), HBeAg is secreted and accumulates in serum as an ...
... hepatitis B surface antigen, anti-hepatitis B core, and anti-hepatitis B surface). A person who has never been exposed to ... When a person gets a hepatitis B vaccine then the most common test for hepatitis B will show them to be positive. The usual ... "WHO , Hepatitis B". who.int. World Health Organization. 2011. Retrieved 7 July 2011. See the table "HBV serological markers in ... hepatitis B but has gotten the vaccine will be positive for anti-HBs but negative for the other two tests in the panel. Other ...
Hepatitis B: Two periods may be referred to as window period in hepatitis B infection: 1) the period that elapses during HBsAg ... During the window of HBsAg to HBsAb seroconversion, IgM anti-core (HBc-IgM) is the only detectable antibody. HBV DNA may be ... to HBsAb seroconversion, i.e. between the disappearance of surface antigen (HBsAg) from serum and the appearance of HBsAb (anti ... This window period does not occur in persons who develop chronic hepatitis B, i.e. who continue to have detectable HBV DNA for ...
"Intramembrane processing by signal peptide peptidase regulates the membrane localization of hepatitis C virus core protein and ... In mice, a nonamer peptide originating from the SPP protein serves as minor histocompatibility antigen HM13 that plays a role ... SPP also plays a pathophysiological role; it cleaves the structural nucleocapsid protein (also known as core protein) of the ... Hepatitis C virus and thus influences viral reproduction rate. ...
McLauchlan J, Lemberg MK, Hope G, Martoglio B (2002). "Intramembrane proteolysis promotes trafficking of hepatitis C virus core ... The minor histocompatibility antigen 13 is a nonamer peptide that originates from a protein encoded by the H13 gene. The ... and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs ... Minor histocompatibility antigen H13 is a protein that in humans is encoded by the HM13 gene. ...
Hepatitis B Surface Antigen Antibody to Hepatitis C Antibody to HIV, usually subtypes 1 and 2 Serologic test for Syphilis The ... Donated blood is tested by many methods, but the core tests recommended by the World Health Organization are these four: ... For example, the HIV antibody test will not detect a recently infected donor, so some blood banks use a p24 antigen or HIV ... The screening includes testing for diseases that can be transmitted by a blood transfusion, including HIV and viral hepatitis. ...
Immunoglobulin M antibody to hepatitis C virus core antigen: Correlations with viral replication, histological activity, and ... Improved serodiagnosis of hepaptis C virus Hepatitis C infection with synthetic peptide antigen from capsid protein. Proc Natl ... Patterns and prevalence of hepatitis type C infection in post-transfusion non-A, non-B hepatitis. J Inf Dis 1993; 167: 1296- ... Human lymphocyte bearing 1a-like antigens [now termed HLA-DK or class 1 MHC antigen]: Absence in patients with infantile ...
... such as the hepatitis B surface or core antigen), anti-viral antibodies (such as the anti-hepatitis B surface antibody or anti- ... Viral hepatitis is caused by five different viruses (hepatitis A, B, C, D, and E). Hepatitis A and hepatitis E behave similarly ... and are self-limiting illnesses that do not lead to chronic hepatitis. Hepatitis B, hepatitis C, and hepatitis D are ... hepatitis D is predominant among hepatitis B virus co-infected individuals. Similar to Hepatitis A, hepatitis E manifests as ...
... are large molecules consisting of a lipid and a polysaccharide composed of O-antigen, outer core and inner core joined by a ... Hep) moieties. The outer core oligosaccharide chain varies depending on the bacterial strain. The term lipooligosaccharide is ... The O antigen is attached to the core oligosaccharide, and comprises the outermost domain of the LPS molecule. The composition ... It comprises three parts: O antigen (or O polysaccharide) Core oligosaccharide Lipid A A repetitive glycan polymer contained ...
The icosahedral core particle is made of 180 or 240 copies of the core protein, alternatively known as hepatitis B core antigen ... "Predictive factors for reactivation of hepatitis B following hepatitis B e antigen seroconversion in chronic hepatitis B". ... Hepatitis D (HDV) can occur only with a concomitant hepatitis B infection, because HDV uses the HBV surface antigen to form a ... the HBsAg will become undetectable and will be followed by IgG antibodies to the hepatitis B surface antigen and core antigen ( ...
One effort involved using hepatitis B core antigen modified to carry a hepatitis C protein. In a 2006 study, 60 patients ... Chen, Jia-Yu; Li, Fan (28 December 2006). "Development of hepatitis C virus vaccine using hepatitis B core antigen as immuno- ... Although vaccines exist for hepatitis A and hepatitis B, development of a hepatitis C vaccine has presented challenges. No ... Inovio is developing a synthetic multi-antigen DNA vaccine covering hepatitis C virus (HCV) genotypes 1a and 1b and targeting ...
... encoding the core antigen and pre-core protein which are processed and secreted as DHBcAg S-ORF - codes for the surface antigen ... is composed of the virus core antigen (DHBcAg) and surrounds the DNA genome and viral polymerase. The viral genome is a ... The Duck Hepatitis B virus has provided a basis for the use of vaccines and prophylactic treatments for individuals at high ... Duck Hepatitis B virus, abbreviated DHBV, is part of the Avihepadnavirus genus of the Hepadnaviridae, and is the causal agent ...
The autoimmune target of anti-sp100 is the sp100 nuclear antigen which was identified by its association with primary biliary ... The sera of these patients exhibit a characteristic "nuclear dots" pattern in indirect immunofluorescence (IIF) on Hep-2 cells ... Bolded areas represent the core epitope.) Szostecki C, Guldner HH, Netter HJ, Will H (1990). "Isolation and characterization of ... cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis ...
The product of the X gene is hepatitis B x antigen (HBxAg). It may be involved in carcinogenesis. Basal core promoter mutants ... A precore mutant is a variety of hepatitis B virus that does not produce hepatitis B virus e antigen (HBeAg). These mutants are ... core promoter mutants limits the probability of response to peginterferon in hepatitis B e antigen-positive chronic hepatitis B ... They are readily detectable by HBV DNA in serum, but hepatitis B e antigen (HbeAg) is absent. The X gene codes for HBxAg. ...
There are four known genes encoded by the genome called C, P, S, and X. The core protein is coded for by gene C (HBcAg), and ... The DNA polymerase is encoded by gene P. Gene S is the gene that codes for the surface antigen (HBsAg). The HBsAg gene is one ... Non primate species included the woodchuck hepatitis virus, the ground squirrel hepatitis virus and arctic squirrel hepatitis ... the Ground squirrel hepatitis virus, Woodchuck hepatitis virus, and the Woolly monkey hepatitis B virus. The genus is ...
Matched antibody pairs Anti-idiotypic Antibodies HBV Core Antigen Antibody Isotyping Kits Protein Antigen Expression Service ... "Molecular detection of hepatitis B virus (HBV) among voluntary ELISA positive blood donors in Almadinah Almunawwarah". Science ... Later, various kinds of antibody, viral antigens, reagents, medical kits and biological service were launched to broaden market ... "Human Bone Marrow Stromal Cell Antigen 1, BST1 ELISA Kit" (PDF). funakoshi. ...
The core of Transgene's discovery platform is gene transfer. This process requires vectors to deliver genes to the target cells ... The therapy is based on a recombinant vaccinia virus expressing the MUC1 antigen and the human cytokine, interleukin-2 (IL2). ... an immunotherapy product that is in Phase II clinical trials for the treatment of chronic hepatitis C infections (HCV); and ...
... hepatitis b antigens MeSH D23.050.327.495.500.450 --- Hepatitis B core antigens MeSH D23.050.327.495.500.469 --- hepatitis b e ... hepatitis c antigens MeSH D23.050.327.495.752 --- hepatitis delta antigens MeSH D23.050.327.520 --- hiv antigens MeSH D23.050. ... hepatitis antigens MeSH D23.050.327.495.249 --- hepatitis a antigens MeSH D23.050.327.495.500 --- ... hla-a antigens MeSH D23.050.301.500.450.370.372 --- hla-a1 antigen MeSH D23.050.301.500.450.370.374 --- hla-a2 antigen MeSH ...
Bat hepatitis virus Ground squirrel hepatitis virus Hepatitis B virus Woodchuck hepatitis virus Woolly monkey hepatitis B virus ... Four main open reading frames are encoded (ORFs) and the virus has four known genes which encode seven proteins: the core ... capsid protein, the viral polymerase, surface antigens-preS1, preS2, and S, the X protein and HBeAg. The X protein is thought ... Group: dsDNA-RT Order: Unassigned Family: Hepadnaviridae Genus: Avihepadnavirus Duck hepatitis B virus Heron hepatitis B virus ...
Hepatitis B virus DNA in patients with chronic liver disease and negative tests for hepatitis B surface antigen. N. Engl. J. ... Gut, 2005 Aug,54(8):1162-8. PAVIO N, BOUCREUX D, BATTAGLIA S, ARNULF B, SOBESKY R, HERMINE O, BRECHOT C. Hepatitis C virus core ... Distinct Hepatitis C Virus Core and F protein quasispecies in tumoral and nontumoral hepatocytes. Hepatology 2007 Dec;46(6): ... Hepatitis C virus core protein shows an exclusively cytoplasmic localization and associates to cellular lipid storage droplets ...
... hepatitis delta virus small delta antigen). p300/CBP have also been observed to acetylate β-catenin, RIP140, PCNA, the DNA ... The core region, which corresponds to motifs A, B, and D of the GNAT proteins, is flanked on opposite sides by N- and C- ... While the central core domain (motif A in GNATs) is involved in acetyl-CoA binding and catalysis, the N- and C-terminal ... The central core and the flanking segments together form a cleft over the former, which is where histone substrates can bind ...
... antigen - antigen presentation - antigen-presenting cell (APC) - antineoplastic - antiprotozoal - antiretroviral drugs - ... hepatitis - hepatitis C and HIV coinfection - hepatomegaly - herpes simplex virus 1 (HSV-1) - herpes simplex virus 2 (HSV-2) - ... core - core protein - correlates of immunity/correlates of protection - CPCRA - creatinine - cross-resistance - cryotherapy - ... human leukocyte antigens (HLA) - human papilloma virus (HPV) - human T cell lymphotropic virus type I (HTLV-I) - human T cell ...
December 1993). "Human leukocyte antigen A1-B8-DR3-DQ2-DPB1*0401 extended haplotype in autoimmune hepatitis". Hepatology. 18 (6 ... In the US Caucasians, 57% of haplotypes with a core component, Cw7-B8, extend from HLA-A1 locus to DQ2 locus. This compares ... In autoimmune hepatitis[edit]. In 1972, a link between "HLA A1,8" (current:HLA A1-B8) active chronic hepatitis, subsequently B8 ... human leukocyte antigens DR4 and A1-B8-DR3 are independent risk factors". Hepatology. 13 (4): 701-6. doi:10.1002/hep.1840130415 ...