"Streptococcus iniae beta-hemolysin streptolysin S is a virulence factor in fish infection". Dis. Aquat. Org. 76 (1): 17-26. doi ... doi:10.1016/S0044-8486(96)01450-0. Shoemaker CA, Evans JJ, Klesius PH (2000). "Density and dose: factors affecting mortality of ...
The protein has structural similarities to other toxins, including haemolysin E and B. cereus toxins HlbB and NheA. No other ... Recent studies suggest this protein functions better in combination with other virulence factors such as other Cry proteins and ... "Bacillus thuringiensis metalloproteinase Bmp1 functions as a nematicidal virulence factor". Applied and Environmental ... "Structure of the hemolysin E (HlyE, ClyA, and SheA) channel in its membrane-bound form". J.Biol.Chem. 281, 23042-23049 Zhang, F ...
MspA porin (octamer, n=S=16) and α-hemolysin (heptamer n=S=14) . These proteins are secreted. ... Outer membrane efflux proteins, also known as trimeric outer membrane factors (n=12,S=18) including TolC and multidrug ...
These include proteases, thermonucleases, coagulases, DNAase, lipase, hemolysin, clumping factor, leukotoxin, enterotoxin, ... The pore-forming cytotoxins, α-hemolysin and β-hemolysin, lyse erythrocytes of sheep and rabbits. Leukotoxin destroys host ... CoPS strains typically express more virulence factors. This CoPS characteristic is a contributing factor to its biochemical ... pseudintermedius is an opportunistic pathogen that secretes immune modulating virulence factors, has many adhesion factors, and ...
Both are virulence factors facilitating respiratory tract colonization by B. pertussis. The cyaA-ACD binds to a M2 integrin ... Bifunctional hemolysin/adenylate cyclase is a protein that in B. pertussis (the bacteria that causes whooping cough) is encoded ... The ACD of CyaA shares a similar structure and mechanism of activation with anthrax edema factor (EF). However, the ... This protein in turn is cleaved into a calmodulin-sensitive adenylate cyclase (cyaA-ACD) and hemolysin. ...
The toxin may be considered a virulence factor, since it is crucial for the virulence of L. monocytogenes. Listeriolysin O is a ... Listeriolysin O (LLO) is a hemolysin produced by the bacterium Listeria monocytogenes, the pathogen responsible for causing ... Virulence Factors of Pathogenic Bacteria. "Pathogenicity islands in Listeria: LIPI-1." State Key Laboratory for Molecular ... This allows the bacteria to live intracellularly, where they are protected from extracellular immune system factors such as the ...
The P fimbriae island contains virulence factors such as haemolysin, pili, cytotoxic necrosing factor, and uropathogenic ... 1990). "Deletions of chro- mosomal regions coding for fimbriae and hemolysins occur in vivo and in vitro in various ... Pathogenicity islands carry genes encoding one or more virulence factors, including, but not limited to, adhesins, secretion ... Rhodococcus equi virulence plasmid pathogenicity island encodes virulence factors for proliferation in macrophages. The SaPI ...
It has been found to utilize several proteases, secretion systems, hemolysins, resistance factors, and quorum sensing. Some of ... al made note of several metalloprotease and hemolysin genes in the draft genome sequence published in 2015, several of which ... V. coralliilyticus possesses a host of virulence factors that contribute to its pathogenicity. ... "Factors affecting infection of corals and larval oysters by Vibrio coralliilyticus". PLOS ONE. 13 (6): e0199475. doi:10.1371/ ...
Due to its short half-life and tendency to remain bound to cells upon secretion, hemolysin has scarcely been identified in ... Singh, B. R.; Singh, Y.; Tiwari, A. K. (3 March 1997). "Characterisation of virulence factors of Serratia strains isolated from ... Ruan, Yuan; Braum, Volkmar (1 August 1990). "Hemolysin as a marker for Serratia". Archives of Microbiology. 154 (3): 221-225. ... Pinna, Antonio; Usai, Donatella; Sechi, Leonardo A.; Carta, Arturo; Zanetti, Stefania (2011). "Detection of virulence factors ...
Although some potential virulence factors (e.g. endotoxins, hemolysins, enterotoxins, adherence factors) have been identified, ...
Several virulence factors contribute to the pathogenesis of GAS, such as M protein, hemolysins, and extracellular enzymes. ... Environmental factors, such as less crowding and the increase of family living space, can account for the reduction in ... Severe GAS disease may also occur in healthy persons with no known risk factors. All severe GAS infections may lead to shock, ... Indeed, the many virulence factors of GAS can influence the epigenetics of the host. Furthermore, persons with suppressed or ...
The prototypical RTX toxin, α-haemolysin (HlyA; TC# 1.C.11.1.3), is a common virulence factor in uropathogenic E. coli (UPEC), ... EHEC haemolysin (EHEC-Hly) was discovered in the EHEC serotype O157:H7. The EHEC-Hly operon contains four E. coli hly homologs ... RtxA is a virulence factor involved in cholera which facilitates colonization of V. cholerae the small intestine. RtxA causes ... Adenylate cyclase toxin (ACT or CyaA), is a primary virulence factor in Bordetella pertussis. CyaA is a multifunctional RTX ...
The CAMP factor produced by GBS acts synergistically with the staphylococcal β-hemolysin inducing enhanced hemolysis of sheep ... Though maternal GBS colonization is the key determinant for EOD, other factors also increase the risk. These factors include ... As other virulent bacteria, GBS harbors an important number of virulence factors (virulence factors are molecules produced by ... β-hemolysin. Today it is considered that GBS pigment and hemolysin are identical or closely related molecules. GBS colonization ...
The CAMP factor acts synergistically with the staphylococcal β-haemolysin inducing enhanced haemolysis of sheep or bovine ... Prematurity has been reported to be the main risk factor. Each week of decreasing gestation increases the risk by a factor of ... Though maternal GBS colonization is the key determinant for GBS-EOD, other factors also increase the risk. These factors are: ... β-haemolysin. The GBS capsule is probably the key virulence factor because it helps GBS escape from the host defence mechanisms ...
Sequencing has revealed a bundle of twelve proteins and some putative hemolysins are potential virulence factors of T. pallidum ...
The Dr adhesins bind Dr blood group antigen (Dra) which is present on decay accelerating factor (DAF) on erythrocytes and other ... Uropathogenic E. coli produce alpha- and beta-hemolysins, which cause lysis of urinary tract cells.[citation needed] Another ... Identified Virulence Factors of UPEC : Adherence, State Key Laboratory for Moleclular Virology and Genetic Engineering, Beijing ... Unlike normal flora E. coli, the pathogenic varieties produce toxins and other virulence factors that enable them to reside in ...
Several virulence factors account for the remarkable pathogenicity of A. pleuropneumoniae. The more important ones include the ... As the bacteria replicate, they release cytotoxins (in the form of Apx toxins), hemolysins and the LPS on their outer membranes ... 2010). "Virulence factors of Actinobacillus pleuropneumoniae involved in colonization, persistence and induction of lesions in ... The main difference between the serotypes is the expression of Apx toxins and other virulence factors. The bacterium rapidly ...
The hemolysin portion of the protein then binds to the target membrane and inserts itself into the bilayer. The adenylate ... Adenylate cyclase toxin is a virulence factor produced by some members of the genus Bordetella. Together with the pertussis ... The part of the toxin from residue 400 to the C-terminus, called hemolysin, is structurally related to a large family of ... An example is α-hemolysin from Escherichia coli or RtxA from Vibrio cholerae. Adenylate cyclese toxin binds to target cells by ...
... where they overcome the insect's defense systems and produce numerous virulence factors such as hemolysin and cytotoxin. They ...
A hemolysin activity, named NlyA, with immunological reactivity to Escherichia coli anti-HlyA antibody, was identified in ... It also contains a number of ATP-binding cassette (ABC) proteins that may be linked to the secretion of virulence factors. F. ... Acid phosphatase AcpA has been found in other bacteria to act as a hemolysin, whereas in Francisella, its role as a virulence ... This protein is located in a putative pathogenicity island regulated by the transcription factor MglA. F. tularensis, in vitro ...
... such as adenylate cyclase-hemolysin, dermonecrotic toxin and tracheal cytotoxin. These factors are then expressed and regulated ... The virulence factors identified in the bordetella are common to all three species. These include adhesins, such as filamentous ... In these conditions, some, but not all of the virulence factors associated with the Bvg+ phase are expressed, suggesting this ... toxin-hemolysin. Membrane translocation of AC domain polypeptide promotes calcium influx into CD11b+ monocytes independently of ...
... pigment and hemolysin are identical or closely related molecules and it has also been reported that they are important factors ... pigment and hemolysin are identical or closely related molecules and it has also been reported that they are important factors ... Rosa-Fraile M, Dramsi S, Spellerberg B (2014). "Group B streptococcal haemolysin and pigment, a tale of twins" (PDF). FEMS ... Christopher-Mychael Whidbey (2015). Characterization of the Group B Streptococcus Hemolysin and its Role in Intrauterine ...
While the VvhA and MARTX toxin are factors in the bacteria's virulence, in vivo studies in mice suggest that the MARTX toxin is ... Exotoxin: V. vulnificus produces a number of extracellular toxins such as metalloprotease VvpE, cytolysin/hemolysin VvhA, and ... Lack of disease recognition, and also of the risk factors, presentation, and cause, were and are major obstacles to good ... 2006). "Prognostic factors and antibiotics in Vibrio vulnificus septicemia". Archives of Internal Medicine. 166 (19): 2117-23. ...
... specific targeting of virulence factors with antibodies may be the next step to treating this pathogen. Alpha-hemolysin has ... Alpha-toxin is also one of the key virulence factors in S. aureus pneumonia. The level of alpha-toxin expressed by a particular ... Song L, Hobaugh MR, Shustak C, Cheley S, Bayley H, Gouaux JE (December 1996). "Structure of staphylococcal alpha-hemolysin, a ... Bubeck Wardenburg J, Bae T, Otto M, Deleo FR, Schneewind O (December 2007). "Poring over pores: alpha-hemolysin and Panton- ...
O factor CAMP producido polo GBS actúa sinerxicamente coa β-hemolisina estafilocócica inducindo a potenciación da hemólise de ... "Group B streptococcal haemolysin and pigment, a tale of twins" (PDF). FEMS Microbiol Rev. 38 (5): 932-946. doi:10.1111/1574- ... Aínda que a colonización materna por GBS é o factor clave determinante para a enfermidade de comezo temperán, outros factores ... é só un importante factor de virulencia do GBS, senón que tamén é un excelente candidato para o desenvolvemento dunha vacina ...
Virulence factors associated with S. schleiferi have been identified to include the production of fatty acid modifying enzyme ( ... In contrast to S. schleiferi which produces β-hemolysin and consequently exhibits a complete (β) hemolysis, strains of S. ... The production of fatty acid modifying enzyme (FAME) and lipase has been identified as potential virulence factors in various ... Eckholm NG, Outerbridge CA, White SD, Sykes JE (February 2013). "Prevalence of and risk factors for isolation of meticillin- ...
Several virulence factors of P. penneri can make infections from this invasive pathogen more pronounced, persistent, and harder ... It also has a filterable cytotoxic alpha-hemolysin rarely found in other Proteus species. A highly active urease produced by P ... Similar to other Proteus species, P. penneri has a cell-bound hemolytic factor, which has been shown to facilitate penetration ... Rózalski A, Kwil I, Torzewska A, Baranowska M, Staczek P (2007). "[Proteus bacilli: features and virulence factors]". Postepy ...
Despite this not being a pathogenic bacterium, it possess some virulence genes (including virulence factor mviN, hemolysin or N ...
It has also been proposed that granadaene is indeed the hemolysin of S.agalactiae, and because the GBS hemolysin is a broad- ... spectrum cytolysin able to destroy many eukaryotic cells, it is considered an important virulence factor for GBS. In addition ... Rosa-Fraile M, Dramsi S, Spellerberg B (2014). "Group B streptococcal haemolysin and pigment, a tale of twins" (PDF). FEMS ...
... and an outer membrane factor (OMF). An example is the secretion of hemolysin (HlyA) from E. coli where the inner membrane ABC ... TolC allows hemolysin to be transported across the two membranes, bypassing the periplasm. Bacterial drug resistance has become ... This is caused by several factors, one of which is increased expulsion of the drug from the cell by ABC transporters. For ... An example is the E. coli hemolysin exporter HlyB. Importers have an inverted organization, that is, NBD-TMD-NBD-TMD, where the ...
Hemolysins have proved to be a damaging factor for vital organs, through the activity of Staphylococcus aureus. S.aureus is a ... Staphylococcus aureus hemolysins[edit]. α-hemolysin[edit]. Alpha(α)-hemolysin of Staphylococcus aureus: macromolecular ... γ-Hemolysin[edit]. γ-Hemolysins are pore-forming toxins in the same family as α-Hemolysin. They are unique in that they come in ... β-hemolysin[edit]. β-hemolysin (hlb; Q2FWP1) is a Phospholipase C toxin secreted by S. aureus. Upon investigating sheep ...
... no pathogenic adhesion factors (e.g. no CFA I/II, P, M and S fimbriae), no hemolysins, no serum resistance (i.e. no risk of ...
There, they have a variety of effects, including reduced synthesis of anticoagulation factors such as tissue factor pathway ... Type II, membrane-damaging toxins, destroy cell membranes in order to enter and include hemolysins and phospholipases. Type III ... This signaling results in the activation of nuclear factor kappaB (NF-κB), which leads to transcription of a number of genes ...
C. tetani also produces the exotoxin tetanolysin, a hemolysin, that causes destruction of tissues.[5] ...
Some S. haemolyticus strains produce enterotoxins (SE) and/or hemolysins.[9][17] In a study of 64 S. haemolyticus strains, ... The ability to adhere to medical devices and subsequently form biofilms is a major virulence factor associated with S. ... Biofilm formation is influenced by a variety of factors including carbohydrates, proteins, and extracellular DNA. Detachment ... CP is considered a virulence factor because it provides resistance against complement-mediated polymorphonuclear neutrophil ...
Richard M, Drouin R, Beaulieu AD (1998). „ABC50, a novel human ATP-binding cassette protein found in tumor necrosis factor- ... Crystal structure of the nucleotide-binding domain of the ABC-transporter haemolysin B: identification of a variable region ...
Several virulence factors are thought to contribute to E. faecalis infections. A plasmid-encoded hemolysin, called the ... Survival and virulence factors[edit]. *Endures prolonged periods of nutritional deprivation. *Binds to dentin and proficiently ... "Hemolysin of Streptococcus faecalis subspecies zymogenes contributes to virulence in mice". Infection and Immunity. 45 (2): ... "Plasmid-associated hemolysin and aggregation substance production contribute to virulence in experimental enterococcal ...
To escape from the phagosome, the bacteria secrete phospholipase D and hemolysin C. This causes disruption of the phagosomal ... Host factors associated with severe or fatal Rocky Mountain spotted fever include advanced age, male sex, African or Caribbean ...
... procoagulant factors and tissue factor activation, contributing to the formation of thrombosis. This can lead to esophageal ... Hemolysins damage the red blood cell's cytoplasmic membrane, causing lysis and eventually cell death. Hemolysis inside the body ... After the blood collection process, in vitro hemolysis can still occur in a sample due to external factors, such as prolonged ... Hemolysin Glucose-6-phosphate dehydrogenase deficiency Wells, John C. (2008). Longman Pronunciation Dictionary (3rd ed.). ...
Once the Fc receptor binds to the Fc region of the antibody, the NK cell releases cytotoxic factors that cause the death of the ... described as hemolysins. These bacteria target the CD18 portion of leukocytes, which has historically been shown to impact ADCC ...
... immunologic factors MeSH D27.505.696.477.136 - agglutinins MeSH D27.505.696.477.136.377 - hemagglutinins MeSH D27.505.696.477. ... hemolysins MeSH D27.888.569.213.545 - leukocidins MeSH D27.888.569.242 - dermotoxins MeSH D27.888.569.271 - immunotoxins MeSH ... endothelium-dependent relaxing factors MeSH D27.505.954.427 - central nervous system agents MeSH D27.505.954.427.010 - ...
The zeta-toxin is characterised as haemolysin. The type and severity of the disease caused depends on penetration of the ... and many other clostridium species cause gas gangrene Spontaneous infection is mostly associated with predisposing factors of ... The delta-toxin is characterised as oxygen labile haemolysin. The epsilon-toxin is characterised as lecithino-vitelin[check ...
... vascular endothelial growth factor a MeSH D12.776.467.100.800.300 - vascular endothelial growth factor b MeSH D12.776.467.100. ... hemolysins MeSH D12.776.377.715.548.114.573 - immune sera MeSH D12.776.377.715.548.114.573.203 - antilymphocyte serum MeSH ... fibroblast growth factor 4 MeSH D12.776.624.664.700.112 - fibroblast growth factor 6 MeSH D12.776.624.664.700.114 - fms-like ... peptide elongation factor g MeSH D12.776.835.700.350.700 - peptide elongation factor tu MeSH D12.776.835.700.350.800 - peptide ...
Its virulence factors include pertussis toxin, adenylate cyclase toxin, filamentous hæmagglutinin, pertactin, fimbria, and ... Sebo, Peter; Osicka, Radim; Masin, Jiri (2014-08-04). "Adenylate cyclase toxin-hemolysin relevance for pertussis vaccines". ... PTx, formerly known as lymphocytosis-promoting factor, causes a decrease in the entry of lymphocytes into lymph nodes, which ...
YmoA modulates the expression of various virulence factors, such as Yop proteins and YadA adhesin, in response to temperature. ... In molecular biology, the haemolysin expression modulating protein family is a family of proteins. This family consists of ... "Role of the Hha/YmoA family of proteins in the thermoregulation of the expression of virulence factors". Int. J. Med. Microbiol ... is involved in the regulation of expression of the toxin alpha-haemolysin in response to osmolarity and temperature. ...
By macroscopically monitoring the dye's properties over time, and controlling outside factors, the ability of a compound to act ... as supramolecular or covalent bonding of cyclodextrins to alpha-hemolysin demonstrates. An ion channel can be characterized by ...
... the thermostable direct hemolysin gene (tdh) and/or the tdh-related hemolysin gene (trh). Strains possessing one or both of ... The PAI can be acquired by horizontal gene transfer and contains genes for several virulence factors. Two fully sequenced ... these hemolysins exhibit beta-hemolysis on blood agar plates. A distinct correlation seems to exist between presence of tdh, ...
It is also distinguished from classic biotypes by the production of hemolysins. At the turn of the 20th century, the Turkish ... Jude, B.A.; Kirn, T.J.; & Taylor, R.K. (2005). "A colonization factor links vibrio cholerae environmental survival and human ... Later in 1905, Kraus and Pribram found that the bacteria, which produced soluble hemolysin, were more related to non-cholera ...
These factors include adhesins, invasins, and antiphagocytic factors. The factors, including toxins, hemolysins and proteases, ... it is an example of a virulence factor from a fungus. Other virulence factors include factors required for biofilm formation (e ... When placed at random, the transposon may be placed next to a virulence factor or placed in the middle of a virulence factor ... These obtained bacterial virulence factors have two different routes used to help them survive and grow: The factors are used ...
... factor viiia MeSH D12.776.124.125.375.310 - factor ixa MeSH D12.776.124.125.400.315 - factor xa MeSH D12.776.124.125.425.320 - ... hemolysins MeSH D12.776.124.486.485.114.573 - immune sera MeSH D12.776.124.486.485.114.573.203 - antilymphocyte serum MeSH ... factor xia MeSH D12.776.124.125.450.324 - factor xiia MeSH D12.776.124.125.475.500 - factor xiiia MeSH D12.776.124.125.500.265 ... complement factor h MeSH D12.776.124.486.274.920.325.210 - complement factor i MeSH D12.776.124.486.274.920.662 - complement ...