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*  BUB1
In vitro knockdown of Bub1 in p53 impaired cells (e.g. HeLa cells) caused aneuploidy. Whether aneuploidy alone is a sufficient ... In humans Bub1 accumulates gradually during G1 and S phase of the cell cycle, peaks at G2/M, and drops dramatically after ... Cell. 32 (3): 394-405. doi:10.1016/j.molcel.2008.09.017. PMC 2644263 . PMID 18995837. UniProt: O43683 "BUB1 protein (Homo ... Jeganathan K, Malureanu L, Baker DJ, Abraham SC, van Deursen JM (Oct 2007). "Bub1 mediates cell death in response to chromosome ...
*  List of Stuff You Should Know episodes
"SYSK Selects: How HeLa Cells Work". HowStuffWorks. Retrieved 2017-07-08. "SYSK Selects: How HeLa Cells Work". HowStuffWorks. ... How HeLa Cells Work. HowStuffWorks. Retrieved 2016-03-17. How Underwater Tunnels Work. HowStuffWorks. Retrieved 2016-03-17. How ... How Stem Cells Work. HowStuffWorks. Retrieved 2016-03-20. How Royalty Works. HowStuffWorks. Retrieved 2016-03-20. How Socialism ...
*  List of Stuff You Should Know episodes (2013)
How HeLa Cells Work. HowStuffWorks. Retrieved 2016-03-17. How Underwater Tunnels Work. HowStuffWorks. Retrieved 2016-03-17. How ...
*  Katarína Horáková
Jantovà, S.; Horàkovà, K. (1993). "9-Hydroxybenfluron induced inhibition of proliferation and metabolism in hela cells". Cell ... "Degeneration of HeLa-cells induced by the cytotoxic effect of isothiocyanates or by the starvation of cells". Acta morphologica ... 2. Effect of l-alpha-ethyl ester of 2-isothiocyanate propionic acid on hela cell division and metabolism]. Biológia (in Slovak ... Horáková, K; Navarová, J; Nemec, P; Kettner, M (1974). "Effect of dactylarin of HeLa cells". The Journal of Antibiotics. 27 (6 ...
*  Agrobacterium
Kunik, T.; Tzfira, T; Kapulnik, Y; Gafni, Y; Dingwall, C; Citovsky, V (2001). "Genetic transformation of HeLa cells by ... By altering the hormone balance in the plant cell, the division of those cells cannot be controlled by the plant, and tumors ... The plasmid T-DNA is integrated semi-randomly into the genome of the host cell, and the tumor morphology genes on the T-DNA are ... Agrobacterium attaches to and genetically transforms several types of human cells by integrating its T-DNA into the human cell ...
*  Agrobacterium tumefaciens
"Genetic transformation of HeLa cells by Agrobacterium". Proceedings of the National Academy of Sciences. 98 (4): 1871-1876. doi ... Jun 1977). "Stable incorporation of plasmid DNA into higher plant cells: the molecular basis of crown gall tumorigenesis". Cell ... This stimulates cell proliferation and gall formation. The T-DNA contains genes for encoding enzymes that cause the plant to ... The Ti plasmid integrates a segment of its DNA, known as T-DNA, into the chromosomal DNA of its host plant cells. A. ...
*  OSBPL11
"Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the ... Cell. 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. ...
*  Osmotic shock
Olivero P, Stutzin A (2004). "Calcium modulates osmosensitive taurine efflux in HeLa cells". Neurochem Res. 29 (1): 169-76. doi ... This also inhibits the transport of substrates and cofactors into the cell thus "shocking" the cell. Alternatively, at low ... Osmotic shock or osmotic stress is physiologic dysfunction caused by a sudden change in the solute concentration around a cell ... Current research also suggests that osmotic stress in cells and tissues may significantly contribute to many human diseases. In ...
*  SNRPA1
Ohno M; Kataoka N; Shimura Y (1991). "A nuclear cap binding protein from HeLa cells". Nucleic Acids Res. 18 (23): 6989-95. doi: ...
*  Chlorphenamine
Arias-Montaño JA, Young JM (1993). "Characteristics of histamine H1 receptors on HeLa cells". Eur. J. Pharmacol. 245 (3): 291-5 ... "Stable expression of human H1-histamine-receptor cDNA in Chinese hamster ovary cells. Pharmacological characterisation of the ...
*  RNASEH2B
2) Ribonucleotides in mtDNA (Mouse and HeLa cells). Low levels of ribonucleotides incorporation in the nuclear genome may be ... Collins FS, Rossant J, Wurst W (Jan 2007). "A mouse for all reasons". Cell. 128 (1): 9-13. doi:10.1016/j.cell.2006.12.018. PMID ... Cell. 149 (5): 1008-22. doi:10.1016/j.cell.2012.04.011. PMC 3383994 . PMID 22579044. Chon H, Vassilev A, DePamphilis ML, Zhao Y ... 1.000.000 sites per cell, making it the most common endogenous base lesion in the mammalian genome. These lesions are best ...
*  George Otto Gey
HeLa Cell Line Gey isolated the cells taken from a cervical tumor found in a woman named Henrietta Lacks in 1951. These cells ... Controversies Due to the unusual growth capabilities of the HeLa cell line, it contaminated many cell cultures and ruined years ... Lucey, Brendan P.; Nelson-Rees, Walter A.; Hutchins, Grover M. (2009-10-21). "Henrietta Lacks, HeLa Cells, and Cell Culture ... and the use of the HeLa cell line became widespread. The cells were used in the development of the polio vaccine, lead to the ...
*  MCM6
Holthoff HP, Baack M, Richter A, Ritzi M, Knippers R (1998). "Human protein MCM6 on HeLa cell chromatin". J. Biol. Chem. 273 ( ... Cell. Biol. 19 (12): 8003-15. PMC 84885 . PMID 10567526. Ishimi Y, Ichinose S, Omori A, Sato K, Kimura H (September 1996). " ... Cell. Biol. 19 (12): 8003-15. PMC 84885 . PMID 10567526. Ishimi Y, Komamura-Kohno Y, You Z, Omori A, Kitagawa M (2000). " ... Ohtani K, Iwanaga R, Nakamura M, Ikeda M, Yabuta N, Tsuruga H, Nojima H (1999). "Cell growth-regulated expression of mammalian ...
*  LIG4
Robins P, Lindahl T (September 1996). "DNA ligase IV from HeLa cell nuclei". The Journal of Biological Chemistry. 271 (39): ... This interaction stabilizes LIG4 protein in cells; cells that are deficient for XRCC4, such as XR-1 cells, have reduced levels ... variable degrees of immunodeficiency and reduced number of blood cells. Accumulation of DNA damage leading to stem cell ... The sensitivity of haematopoietic stem cells to lig4 deficiency suggests that lig4-mediated NHEJ is a key determinant of the ...
*  DBR1
Arenas J, Hurwitz J (1987). "Purification of a RNA debranching activity from HeLa cells". J. Biol. Chem. 262 (9): 4274-9. PMID ... 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635-48. doi:10.1016/ ...
*  TXNIP
Joguchi A, Otsuka I, Minagawa S, Suzuki T, Fujii M, Ayusawa D (Apr 2002). "Overexpression of VDUP1 mRNA sensitizes HeLa cells ... 25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression". Oncogene. 22 (26): 4035-46. doi:10.1038/ ... 25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression". Oncogene. 22 (26): 4035-46. doi:10.1038/ ... "Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3". Biochimica et ...
*  PTEN (gene)
"PTEN associates with the vault particles in HeLa cells". The Journal of Biological Chemistry. 277 (43): 40247-52. doi:10.1074/ ... The defective protein allows the cell to divide in an uncontrolled way and prevents damaged cells from dying, which can lead to ... The defective protein is unable to stop cell division or signal abnormal cells to die, which can lead to tumor growth, ... This phosphatase is involved in the regulation of the cell cycle, preventing cells from growing and dividing too rapidly. It is ...
*  DNA polymerase alpha catalytic subunit
"On the association of DNA polymerase alpha activity with the nuclear matrix in HeLa cells". Cell Biol. Int. Rep. 15 (2): 131-40 ... Jackson DA, Cook PR (1987). "Different populations of DNA polymerase alpha in HeLa cells". J. Mol. Biol. 192 (1): 77-86. doi: ... sequences controlling expression in cycling and serum-stimulated cells". Mol. Cell. Biol. 11 (4): 2081-95. PMC 359896 . PMID ... Cell. Biol. 11 (4): 2108-15. PMC 359898 . PMID 1848671. Martelli AM, Cocco L, Manzoli FA (1991). " ...
*  Major vault protein
"PTEN associates with the vault particles in HeLa cells". The Journal of Biological Chemistry. 277 (43): 40247-52. doi:10.1074/ ... "PTEN associates with the vault particles in HeLa cells". The Journal of Biological Chemistry. 277 (43): 40247-52. doi:10.1074/ ... "Adult T-cell leukemia cells over-express the multidrug-resistance-protein (MRP) and lung-resistance-protein (LRP) genes". ... "Interaction of vault particles with estrogen receptor in the MCF-7 breast cancer cell". The Journal of Cell Biology. 141 (6): ...
*  DDX46
"Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi: ... Cell. 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. ...
*  SFRS6
"Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the ... Lemaire R, Winne A, Sarkissian M, Lafyatis R (March 1999). "SF2 and SRp55 regulation of CD45 exon 4 skipping during T cell ... Gui JF, Lane WS, Fu XD (June 1994). "A serine kinase regulates intracellular localization of splicing factors in the cell cycle ... Molecular Cell. 6 (2): 307-16. doi:10.1016/S1097-2765(00)00031-9. PMID 10983978. Fossey SC, Mychaleckyj JC, Pendleton JK, ...
*  NOL1
"Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi: ... Cell Biol. 4 (7): 529-33. doi:10.1038/ncb814. PMID 12080348. Holsinger LJ, Ward K, Duffield B, Zachwieja J, Jallal B (2002). " ... Cell. 13 (11): 4100-9. doi:10.1091/mbc.E02-05-0271. PMC 133617 . PMID 12429849. Beausoleil SA, Jedrychowski M, Schwartz D, ... The protein encoded by this gene is a nucleolar antigen expressed in proliferating cells. It is not detectable in non- ...
*  SF3B1
"Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the ... Molecular Cell. 5 (5): 779-87. doi:10.1016/S1097-2765(00)80318-4. PMID 10882114. Brand M, Moggs JG, Oulad-Abdelghani M, Lejeune ...
*  RBMX
"Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the ... Collins FS, Rossant J, Wurst W (Jan 2007). "A mouse for all reasons". Cell. 128 (1): 9-13. doi:10.1016/j.cell.2006.12.018. PMID ... Cell. 154 (2): 452-64. doi:10.1016/j.cell.2013.06.022. PMC 3717207 . PMID 23870131. "Infection and Immunity Immunophenotyping ( ... "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity ...
*  NFIA
"Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the ... Cell. 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. Lu W, Quintero-Rivera F, Fan Y, Alkuraya FS, Donovan DJ, ... Cell. 123 (5): 819-31. doi:10.1016/j.cell.2005.09.023. PMID 16325577. Lin YL, Wang YH, Lee HJ (November 2006). "Transcriptional ...
*  Cervical cancer
In medical research, the most famous immortalised cell line, known as HeLa, was developed from cervical cancer cells of a woman ... First successful in-vitro cell line, HeLa, derived from biopsy of cervical cancer of Henrietta Lacks 1976 - Harald zur Hausen ... adenosquamous carcinoma small cell carcinoma neuroendocrine tumour glassy cell carcinoma villoglandular adenocarcinoma ... It is due to the abnormal growth of cells that have the ability to invade or spread to other parts of the body. Early on, ...