Guanosine
... can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine ... are structurally similar to guanosine. Guanosine was also used to make regadenoson. Guanosine can be found in pancreas, clover ... Guanosine (symbol G or Guo) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9- ... Guanosine is a white, crystalline powder with no odor and mild saline taste. It is very soluble in acetic acid, slightly ...
Guanosine monophosphate
... is known as E number reference E626. In the form of its salts, such as disodium guanylate (E627), ... Guanosine monophosphate is commercially produced by microbial fermentation. As an acyl substituent, it takes the form of the ... Guanosine monophosphate (GMP), also known as 5′-guanidylic acid or guanylic acid (conjugate base guanylate), is a nucleotide ... It is an ester of phosphoric acid with the nucleoside guanosine. GMP consists of the phosphate group, the pentose sugar ribose ...
Guanosine pentaphosphate
E.coli are shown to be more sensitive to accumulations of guanosine tetraphosphate than guanosine pentaphosphate. A complete ... p)ppGpp, guanosine pentaphosphate and tetraphosphate, also known as the "magic spot" nucleotides, are alarmones involved in the ... Kuroda, Akio; Murphy, Helen; Cashel, Michael; Kornberg, Arthur (1997-08-22). "Guanosine Tetra- and Pentaphosphate Promote ...
Guanosine triphosphate
Guanosine-5'-triphosphate (GTP) is a purine nucleoside triphosphate. It is one of the building blocks needed for the synthesis ... Its structure is similar to that of the guanosine nucleoside, the only difference being that nucleotides like GTP have ... ISBN 978-0-323-66162-1. Wikimedia Commons has media related to Guanosine triphosphate. GTP bound to proteins in the PDB ( ... in second-messenger mechanisms where it is converted to guanosine diphosphate (GDP) through the action of GTPases. GTP is ...
Guanosine-diphosphatase
In enzymology, a guanosine-diphosphatase (EC 3.6.1.42) is an enzyme that catalyzes the chemical reaction GDP + H2O ⇌ {\ ... Raychaudhuri P, Ghosh S, Maitra U (1985). "Purification and characterization of a guanosine diphosphatase activity from calf ...
Guanosine deaminase
In enzymology, a guanosine deaminase (EC 3.5.4.15) is an enzyme that catalyzes the chemical reaction guanosine + H2O ⇌ {\ ... This enzyme is also called guanosine aminase. Isihida Y, Shirafiji H, Kida M, Yoneda M (1969). "Studies on the guanosine ... III Preparation and properties of guanosine deaminase". Agric. Biol. Chem. 33: 384-390. doi:10.1080/00021369.1969.10859324. ... The systematic name of this enzyme class is guanosine aminohydrolase. ...
Guanosine phosphorylase
In enzymology, a guanosine phosphorylase (EC 2.4.2.15) is an enzyme that catalyzes the chemical reaction guanosine + phosphate ... The systematic name of this enzyme class is guanosine:phosphate alpha-D-ribosyltransferase. This enzyme participates in purine ... the two substrates of this enzyme are guanosine and phosphate, whereas its two products are guanine and alpha-D-ribose 1- ...
Guanosine diphosphate
DNA Guanosine triphosphate Nucleoside Nucleotide Oligonucleotide RNA Crane, Laura J; Miller, David Lee (1974). "Guanosine ... Guanosine diphosphate, abbreviated GDP, is a nucleoside diphosphate. It is an ester of pyrophosphoric acid with the nucleoside ... Differential interaction of a fluorescent probe with the guanosine nucleotide complexes of bacterial elongation factor Tu". ... guanosine. GDP consists of a pyrophosphate group, a pentose sugar ribose, and the nucleobase guanine. GDP is the product of GTP ...
Cyclic guanosine monophosphate
... (cGMP) is a cyclic nucleotide derived from guanosine triphosphate (GTP). cGMP acts as a second ...
Guanosine-triphosphate guanylyltransferase
In enzymology, a guanosine-triphosphate guanylyltransferase (EC 2.7.7.45) is an enzyme that catalyzes the chemical reaction 2 ... and guanosine triphosphate-guanose triphosphate guanylyltransferase. Warner AH, Beers PC, Huang FL (1974). "Biosynthesis of the ...
Guanosine diphosphate mannose
Nucleoside Nucleotide Guanosine Guanosine diphosphate v t e (Articles without KEGG source, Articles containing unverified ... Guanosine diphosphate mannose or GDP-mannose is a nucleotide sugar that is a substrate for glycosyltransferase reactions in ... "Characterisation of a Leishmania mexicana knockout lacking guanosine diphosphate-mannose pyrophosphorylase". International ...
Guanosine nucleotide dissociation inhibitor
In molecular biology, the Guanosine dissociation inhibitors (GDIs) constitute a family of small GTPases that serve a regulatory ...
TRNA guanosine-2'-O-methyltransferase
Other names in common use include transfer ribonucleate guanosine 2'-methyltransferase, tRNA guanosine 2'-methyltransferase, ... guanosine-2'-O-)-methyltransferase, and S-adenosyl-L-methionine:tRNA (guanosine-2'-O-)-methyltransferase. As of late 2007, two ... In enzymology, a tRNA guanosine-2'-O-methyltransferase (EC 2.1.1.34) is an enzyme that catalyzes the chemical reaction S- ... The systematic name of this enzyme class is S-adenosyl-L-methionine:tRNA guanosine-2'-O-methyltransferase. ...
Cyclic guanosine monophosphate-adenosine monophosphate
... (cyclic GMP-AMP, cGAMP) is the first cyclic di-nucleotide found in ...
Guanosine-5'-triphosphate,3'-diphosphate diphosphatase
... guanosine pentaphosphatase, guanosine pentaphosphate phosphatase, guanosine 5'-triphosphate 3'-diphosphate 5'-phosphatase, and ... guanosine 5'-diphosphate,3'-diphosphate + phosphate Thus, the two substrates of this enzyme are guanosine 5'-triphosphate,3'- ... In enzymology, a guanosine-5'-triphosphate,3'-diphosphate diphosphatase (EC 3.6.1.40) is an enzyme that catalyzes the chemical ... The systematic name of this enzyme class is guanosine-5'-triphosphate,3'-diphosphate 5'-phosphohydrolase. Other names in common ...
Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase
The enzyme guanosine-3′,5′-bis(diphosphate) 3′-diphosphatase (EC 3.1.7.2) catalyzes the reaction guanosine 3′,5′-bis( ... The systematic name is guanosine-3′,5′-bis(diphosphate) 3′-diphosphohydrolase. Other names in common use include guanosine-3′,5 ... Heinemeyer EA, Richter D (1978). "Characterization of the guanosine 5'-triphosphate 3′-diphosphate and guanosine 5′-diphosphate ... Richter D, Fehr S, Harder R (1979). "The guanosine 3′,5′-bis(diphosphate) (ppGpp) cycle. Comparison of synthesis and ...
GDP-mannose 6-dehydrogenase
Other names in common use include guanosine diphosphomannose dehydrogenase, GDP-mannose dehydrogenase, guanosine ... Biosynthesis of guanosine diphosphomannuronate". The Journal of Biological Chemistry. 239: 3127-32. PMID 14245351. Portal: ... diphosphomannose dehydrogenase, and guanosine diphospho-D-mannose dehydrogenase. This enzyme participates in fructose and ...
GMP synthase
Guanosine monophosphate synthetase, (EC 6.3.5.2) also known as GMPS is an enzyme that converts xanthosine monophosphate to ... Guanosine 5'-phosphate formation from xanthosine 5'-phosphate and L-glutamine". Arch. Biochem. Biophys. 79: 91-110. doi:10.1016 ... GUANOSINE 5' MONOPHOSPHATE SYNTHETASE) gene". Blood. 96 (13): 4360-2. doi:10.1182/blood.V96.13.4360. PMID 11110714. Guo D, Han ... "Assignment and ordering of twenty-three unique NotI-linking clones containing expressed genes including the guanosine 5'- ...
GDP-glucosidase
Other names in common use include guanosine diphosphoglucosidase, and guanosine diphosphate D-glucose glucohydrolase. Sonnino S ... Carminatti H, Cabib E (1966). "Guanosine diphosphate D-glucose glucohydrolase". Arch. Biochem. Biophys. 116 (1): 26-33. doi: ...
Guanine
... by the enzyme guanosine phosphorylase: guanosine + phosphate ⇌ {\displaystyle \rightleftharpoons } guanine + alpha-D-ribose 1- ... The guanine nucleoside is called guanosine. With the formula C5H5N5O, guanine is a derivative of purine, consisting of a fused ... Guanine is not synthesized de novo[clarification needed], instead it's split from the more complex molecule, guanosine, ...
Deoxyguanosine diphosphate
It is related to the common nucleic acid guanosine triphosphate (GTP), with the -OH group on the 2' carbon on the nucleotide's ... Cofactor Guanosine "2'-Deoxyguanosine-5'-Diphosphate". DrugBank. (Articles without KEGG source, Articles without UNII source, ...
Katherine Seley-Radtke
Thiophene-expanded guanosine analogues of Gemcitabine. Bioorg Med Chem Lett. 2015;25(19):4274-76. Babkov DA, Valuev-Elliston VT ... Chen, Zhe; Ku, Therese C; Seley-Radtke, Katherine L (2015). "Thiophene-expanded guanosine analogues of Gemcitabine". Bioorganic ...
GMP reductase
NADPH + guanosine 5-phosphate = NADP+ + inosine 5-phosphate + NH3 By converting guanosine nucleotides to inosine nucleotides, ... "OMIM Entry- * 139265 - GUANOSINE MONOPHOSPHATE REDUCTASE; GMPR". omim.org. Retrieved 2022-01-01. Hedstrom L (2012-06-01). "The ... The overall reaction consists of two steps: a deamination step, in which ammonia is released from guanosine and a covalent ... Salvatore D, Bartha T, Larsen PR (November 1998). "The guanosine monophosphate reductase gene is conserved in rats and its ...
Ras GTPase
Ras is a guanosine-nucleotide-binding protein. Specifically, it is a single-subunit small GTPase, which is related in structure ... It consists of two domains: a G domain of 166 amino acids (about 20 kDa) that binds guanosine nucleotides, and a C-terminal ... In the "off" state it is bound to the nucleotide guanosine diphosphate (GDP), while in the "on" state, Ras is bound to ... guanosine triphosphate (GTP), which has an extra phosphate group as compared to GDP. This extra phosphate holds the two switch ...
GDP-4-dehydro-D-rhamnose reductase
Other names in common use include GDP-4-keto-6-deoxy-D-mannose reductase, GDP-4-keto-D-rhamnose reductase, and guanosine ... Barber GA (1968). "The synthesis of guanosine 5'-diphosphate D-rhamnose by enzymes of a higher plant". Biochim. Biophys. Acta. ... Winkler NW, Markovitz A (1971). "Guanosine diphosphate-4-keto-D-rhamnose reductase. A non-stereoselective enzyme". J. Biol. ...
Crithidia luciliae
... one for guanosine, its analogues and inosine; and one for hypoxanthine, adenine and adenosine. "Encyclopedia of Life". ...
Mannose-1-phosphate guanylyltransferase
... guanosine 5'-diphospho-D-mannose pyrophosphorylase, guanosine diphosphomannose pyrophosphorylase, guanosine triphosphate- ... I. Guanosine Diphosphate Mannose Pyrophosphorylase: Purification and Properties". J. Biol. Chem. 239: 3119-26. PMID 14245350. ... Other names in common use include GTP-mannose-1-phosphate guanylyltransferase, PIM-GMP (phosphomannose isomerase-guanosine 5'- ... Munch-Peterson A (1955). "Enzymatic synthesis and phosphorolysis of guanosine diphosphate mannose". Arch. Biochem. Biophys. 55 ...
Aciclovir
... is a nucleoside analogue that mimics guanosine. It works by decreasing the production of the virus's DNA. Aciclovir ...
Nucleobase
Tert-Butylthiol
For example, treatment with 7-methylguanosine gives guanosine. Other N-methylated nucleosides in tRNA are not demethylated by ...