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*  DAB2IP
... is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor gene and is inactivated by ... 2004). "Identification of a novel RAS GTPase-activating protein (RASGAP) gene at 9q34 as an MLL fusion partner in a patient ... Characterization of a novel GTPase-activating protein associated with N-terminal domain of DOC-2/DAB2". J Biol Chem. 277 (15): ... Characterization of a novel GTPase-activating protein associated with N-terminal domain of DOC-2/DAB2". J. Biol. Chem. United ...
*  ARHGAP19
Rho GTPase-activating protein 19 is an enzyme that in humans is encoded by the ARHGAP19 gene. GRCh38: Ensembl release 89: ... ARHGAP19 Rho GTPase activating protein 19". Human ARHGAP19 genome location and ARHGAP19 gene details page in the UCSC Genome ...
*  RALA
"Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity". The Journal of ... "Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity". The Journal of ... Ras-related protein Ral-A (RalA) is a protein that in humans is encoded by the RALA gene on chromosome 7. This protein is one ... "Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of ...
*  RGS19
"GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins". ... Berman DM, Wilkie TM, Gilman AG (1996). "GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha ... 1998). "RGS-GAIP, a GTPase-activating protein for Galphai heterotrimeric G proteins, is located on clathrin-coated vesicles". ... "GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits". Cell. 86 (3): 445-452. doi: ...
*  ARHGAP24
Rho GTPase-activating protein 24 is an enzyme that in humans is encoded by the ARHGAP24 gene. GRCh38: Ensembl release 89: ... "Entrez Gene: ARHGAP24 Rho GTPase activating protein 24". Human ARHGAP24 genome location and ARHGAP24 gene details page in the ... Lavelin I, Geiger B (Feb 2005). "Characterization of a novel GTPase-activating protein associated with focal adhesions and the ... "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome ...
*  STARD13
... serves as a Rho GTPase-activating protein (GAP), a type of protein that regulates members of the Rho family of GTPases ... Nagaraja GM, Kandpal RP (January 2004). "Chromosome 13q12 encoded Rho GTPase activating protein suppresses growth of breast ... StAR-related lipid transfer domain protein 13 (STARD13) also known as deleted in liver cancer 2 protein (DLC-2) is a protein ... It selectively activates RhoA and CDC42 and suppresses cell growth by inhibiting actin stress fiber assembly. The protein ...
*  GTPase-activating protein
EIF5 is a GTPase-activating protein. Furthermore, YopE is a protein domain that is a Rho GTPase-activating protein (GAP), which ... GTPase-activating proteins or GTPase-accelerating proteins (GAPs) are a family of regulatory proteins whose members can bind to ... With a nonfunctional G protein enzyme, GAPs cannot activate the GTPase activity, and the G protein is constitutively on. This ... These G proteins acquire missense mutations that disrupt the inherent GTPase activity of the proteins. The mutant G proteins ...
*  Rho gtpase activating protein 21
... is a protein that in humans is encoded by the ARHGAP21 gene. ARHGAP21 functions preferentially ... Rho GTPase activating protein 21". Retrieved 2017-01-30. Bassères DS, Tizzei EV, Duarte AA, Costa FF, Saad ST (2002). "ARHGAP10 ... a novel human gene coding for a potentially cytoskeletal Rho-GTPase activating protein". Biochem. Biophys. Res. Commun. 294 (3 ... "β-Arrestin 1 inhibits the GTPase-activating protein function of ARHGAP21, promoting activation of RhoA following angiotensin II ...
*  IQ motif containing GTPase activating protein
... (IQGAP) is a carrier protein. It is associated with the Rho GTP-binding protein. ...
*  ARHGAP18
Rho GTPase activating protein 18 is a protein that in humans is encoded by the ARHGAP18 gene. The gene is also known as MacGAP ... "Rho GTPase activating protein 18". Retrieved 2011-12-05. Potkin, S. G.; Turner, J. A.; Fallon, J. A.; Lakatos, A.; Keator, D. B ... ARHGAP18 belongs to a family of Rho GTPase-activating proteins that modulate cell signaling. Model organisms have been used in ...
*  ARHGAP25
Rho GTPase activating protein 25 is a protein that in humans is encoded by the ARHGAP25 gene. The gene is also known as ... "Rho GTPase activating protein 25". Retrieved 2011-12-05. Katoh, M.; Katoh, M. (2004). "Identification and characterization of ... ARHGAP25 belongs to a family of Rho GTPase-modulating proteins that are implicated in actin remodeling, cell polarity, and cell ...
*  ARHGAP44
Rho GTPase activating protein 44 is a protein in humans that is encoded by the ARHGAP44 gene. GRCh38: Ensembl release 89: ... Rho GTPase activating protein 44". Retrieved 2013-05-13. Human ARHGAP44 genome location and ARHGAP44 gene details page in the ...
*  Tubulin GTPase
Tian, G.; Bhamidipati, A.; Cowan, N.J.; Lewis, S.A. (1999). "Tubulin folding cofactors as GTPase-activating proteins. GTP ... Roychowdhury, S.; Panda, D.; Wilson, L.; Rasenick, M.M. (1999). "G protein α subunits activate tubulin GTPase and modulate ... Tubulin GTPase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular Biology portal. ... Tubulin GTPase (EC 3.6.5.6) is an enzyme with systematic name GTP phosphohydrolase (microtubule-releasing). This enzyme ...
*  EIF5
Eukaryotic translation initiation factor 5 is a protein that in humans is encoded by the EIF5 gene. EIF5 is a GTPase-activating ... Das S, Ghosh R, Maitra U (2001). "Eukaryotic translation initiation factor 5 functions as a GTPase-activating protein". J. Biol ... "Eukaryotic translation initiation factor 5 functions as a GTPase-activating protein". J. Biol. Chem. 276 (9): 6720-6. doi: ... 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs ...
*  PARD3
The CDC42 GTPase, which is controlled by nucleotide exchange factors (GEFs; see MIM 606057) and GTPase-activating proteins ( ... Partitioning defective 3 homolog is a protein that in humans is encoded by the PARD3 gene. PARD proteins, which were first ... "The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42". Nat Cell Biol. 2 (8): 531-9. doi:10.1038/ ... "Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in ...
*  RABGAP1
RAB GTPase activating protein 1 is a protein in humans that is encoded by the RABGAP1 gene. GRCh38: Ensembl release 89: ... a GTPase activating protein for Rab6, part of which associates with the centrosome". The EMBO Journal. 18 (7): 1772-82. doi: ... RAB GTPase activating protein 1". Caratù G, Allegra D, Bimonte M, Schiattarella GG, D'Ambrosio C, Scaloni A, Napolitano M, ... "The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed and localised to the Golgi apparatus ...
*  ARHGAP31
The Rho GTPase activating protein 31 is encoded in humans by the ARHGAP31 gene. It is a Cdc42/Rac1 GTPase regulator. ARHGAP31 ... 2002). "The activity of the GTPase-activating protein CdGAP is regulated by the endocytic protein intersectin". J. Biol. Chem. ... Lamarche-Vane N, Hall A (1998). "CdGAP, a novel proline-rich GTPase-activating protein for Cdc42 and Rac". J. Biol. Chem. 273 ( ... 2006). "The human orthologue of CdGAP is a phosphoprotein and a GTPase-activating protein for Cdc42 and Rac1 but not RhoA". ...
*  RAP1GAP
"Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1". Cell. 65 (6): 1033-42. doi:10.1016/ ... Rap1 GTPase-activating protein 1 is an enzyme that in humans is encoded by the RAP1GAP gene. RAP1GAP has been shown to interact ... 1997). "Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and ... 1994). "The RAP1GA1 locus for human Rap1-GTPase activating protein 1 maps to chromosome 1p36.1→p35". Cytogenet. Cell Genet. 66 ...
*  RGS7
... is a GTPase-activating protein (GAP). It accelerates the GTP hydrolysis on G proteins determining their fast inactivation ... Regulator of G-protein signaling 7 is a protein that in humans is encoded by the RGS7 gene. RGS7 is highly enriched in the ... Snow BE, Betts L, Mangion J, Sondek J, Siderovski DP (1999). "Fidelity of G protein β-subunit association by the G protein γ- ... "The R7 RGS Protein Family: Multi-Subunit Regulators of Neuronal G Protein Signaling". Cell Biochemistry and Biophysics. 54 (1-3 ...
*  ARHGAP8
... and GTPase-activating protein domains of a novel Rho GTPase-activating protein, BPGAP1". J. Biol. Chem. 278 (46): 45903-45914. ... Rho GTPase-activating protein 8 is an protein that in humans is encoded by the ARHGAP8 gene. This gene encodes a member of the ... GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal ... "Entrez Gene: ARHGAP8 Rho GTPase activating protein 8". Human ARHGAP8 genome location and ARHGAP8 gene details page in the UCSC ...
*  ARHGAP1
... and GTPase-activating protein domains of a novel Rho GTPase-activating protein, BPGAP1". J. Biol. Chem. 278 (46): 45903-14. doi ... "Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP". Nature. 388 (6643): 693-7. doi: ... "Characterization of the interactions between the small GTPase Cdc42 and its GTPase-activating proteins and putative effectors. ... "Magnesium fluoride-dependent binding of small G proteins to their GTPase-activating proteins". Biochemistry. 38 (45): 14981-7. ...
*  ARHGAP4
Rho GTPase-activating protein 4 is an enzyme that in humans is encoded by the ARHGAP4 gene. It has been shown to regulate cell ... 2002). "p115 Rho GTPase activating protein interacts with MEKK1". J. Cell. Physiol. 192 (2): 200-8. doi:10.1002/jcp.10125. PMID ... "Entrez Gene: ARHGAP4 Rho GTPase activating protein 4". Vogt, DL; Gray, CD; Young Ws, 3rd; Orellana, SA; Malouf, AT (2007). " ... Katoh M, Katoh M (2004). "FNBP2 gene on human chromosome 1q32.1 encodes ARHGAP family protein with FCH, FBH, RhoGAP and SH3 ...
*  ARHGAP5
Rho GTPase-activating protein 5 is an enzyme that in humans is encoded by the ARHGAP5 gene. Rho GTPase activating protein 5 ... Chakravarty G, Roy D, Gonzales M, Gay J, Contreras A, Rosen JM (2000). "P190-B, a Rho-GTPase-activating protein, is ... Vargo-Gogola T, Heckman BM, Gunther EJ, Chodosh LA, Rosen JM (2006). "P190-B Rho GTPase-activating protein overexpression ... "Entrez Gene: ARHGAP5 Rho GTPase activating protein 5". Wennerberg K, Forget MA, Ellerbroek SM, Arthur WT, Burridge K, Settleman ...
*  RANGAP1
Ran GTPase-activating protein 1 is an enzyme that in humans is encoded by the RANGAP1 gene. RanGAP1, is a homodimeric 65-kD ... Becker J, Melchior F, Gerke V, Bischoff FR, Ponstingl H, Wittinghofer A (May 1995). "RNA1 encodes a GTPase-activating protein ... Becker J, Melchior F, Gerke V, Bischoff FR, Ponstingl H, Wittinghofer A (1995). "RNA1 encodes a GTPase-activating protein ... "Entrez Gene: RANGAP1 Ran GTPase activating protein 1". Hochstrasser M (2000). "Biochemistry. All in the ubiquitin family". ...
*  RACGAP1
GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic ... Rac GTPase-activating protein 1 is an enzyme that in humans is encoded by the RACGAP1 gene. Rho GTPases control a variety of ... "Entrez Gene: RACGAP1 Rac GTPase activating protein 1". Naud N, Touré A, Liu J, Pineau C, Morin L, Dorseuil O, Escalier D, ... a new human GTPase-activating protein for Rac and Cdc42 similar to Drosophila rotundRacGAP gene product, is expressed in male ...
*  RHOB
"Identification and characterization of a novel activated RhoB binding protein containing a PDZ domain whose expression is ... 1998). "PRK1 is targeted to endosomes by the small GTPase, RhoB". J. Biol. Chem. 273 (9): 4811-4. doi:10.1074/jbc.273.9.4811. ... Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG". J. Biol. Chem. ... Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG". J. Biol. Chem. ...
*  ARHGAP9
This gene encodes a member of the Rho-GAP family of GTPase activating proteins. The protein has substantial GAP activity ... Rho GTPase-activating protein 9 is an enzyme that in humans is encoded by the ARHGAP9 gene. ... "Entrez Gene: ARHGAP9 Rho GTPase activating protein 9". Human ARHGAP9 genome location and ARHGAP9 gene details page in the UCSC ... encoding a rho-GTPase activating protein". Biochemical and Biophysical Research Communications. 284 (3): 643-9. doi:10.1006/ ...