"Role of the multifunctional CDP/Cut/Cux homeodomain transcription factor in regulating differentiation, cell growth and ... It regulates gene expression, morphogenesis, and differentiation and it also plays a role in cell cycle progression, ... Cux transcription factor by cyclin A-Cdk1 modulates its DNA binding activity in G(2)". J. Biol. Chem. 276 (49): 45780-90. doi: ... associated factor and CBP". Proc. Natl. Acad. Sci. U.S.A. 97 (13): 7166-71. Bibcode:2000PNAS...97.7166L. doi:10.1073/pnas. ...

Growth factors: Growth factors can be used to induce differentiation of a cell or induce secretion of matrix proteins. Common ... growth factors for the application of synthetic cartilage include Insulin-growth factor 1 (IGF-1), Transforming Growth Factor β ... and Growth and Differentiation Factor 5 (GDF-5). Human induced pluripotent stem cells (iPSCs) are an alternative cell source ... Additionally, growth factors have been thoroughly evaluated; however, specific combinations still need to be studied further in ...

... enhances lung myofibroblast differentiation through transforming growth factor β receptor-dependent and -independent pathways ... The protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation ... 289 (5): 2526-36. doi:10.1074/jbc.M113.502617. PMC 3908388. PMID 24344132. Lyons PJ, Muise AM, Ro HS (2005). "MAPK modulates ... 343 (2): 341-5. doi:10.1042/0264-6021:3430341. PMC 1220559. PMID 10510298. Feldkamp ML, Bowles NE, Botto LD (2012). "AEBP1 gene ...

Nepveu A. "Role of the multifunctional CDP/Cut/Cux homeodomain transcription factor in regulating differentiation, cell growth ... Activation of the PI3K-AKT signaling pathway by insulin-like growth factor 1 (IGF1) or by AKT2 overexpression led to the ... Pal R, Ramdzan ZM, Kaur S, Duquette PM, Marcotte R, Leduy L, ... and Nepveu A. "CUX2 Functions As an Accessory Factor in the ... "Differentiation-induced cleavage of Cutl1/CDP generates a novel dominant-negative isoform that regulates mammary gene ...

A mutation in Noggin (NOG) and the Growth Differentiation Factor 5 (GDF5) are the other two causes of SYNS. The S99N mutation ... Tsai SJ, Wu MH, Chen HM, Chuang PC, Wing LY (July 2002). "Fibroblast growth factor-9 is an endometrial stromal growth factor". ... "Entrez Gene: FGF9 fibroblast growth factor 9 (glia-activating factor)". Sánchez L, Chaouiya C (May 2016). "Primary sex ... tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured ...

Growth differentiation factor-3 (GDF3), also known as Vg-related gene 2 (Vgr-2) is protein that in humans is encoded by the ... 2008). "Growth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced ... "Human growth-differentiation factor 3 (hGDF3): developmental regulation in human teratocarcinoma cell lines and expression in ... "Expression pattern of growth/differentiation factor 3 in human and murine cerebral cortex, hippocampus as well as cerebellum". ...

"Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation". ... Colony stimulating factor 1 receptor, DCTN1, DNM1, Dock180, Dystroglycan, EPH receptor A2, ETV6, Epidermal growth factor ... "The beta-subunit of the hepatocyte growth factor/scatter factor (HGF/SF) receptor phosphorylates and associates with CrkII: ... "Entrez Gene: GRB2 growth factor receptor-bound protein 2". Berry DM, Nash P, Liu SK, Pawson T, McGlade CJ (August 2002). "A ...

... cholesterol acyltransferase-1 by transforming growth factor-beta1 during differentiation of human monocytes into macrophages" ( ... 320 (2): 501-5. doi:10.1016/j.bbrc.2004.05.190. PMID 15219857. Yang L, Chen J, Chang CC, Yang XY, Wang ZZ, Chang TY, Li BL ( ... April 2004). "A stable upstream stem-loop structure enhances selection of the first 5'-ORF-AUG as a main start codon for ...

BPE contains the cytokines GDNF, basic fibroblast growth factor and platelet-derived growth factor, which cause differentiation ... The neurotrophic factors used were epidermal growth factor (EGF), fibroblast growth factor-2 (FGF-2), nerve growth factor (NGF ... Many factors promote the growth of MSCs including: platelet-derived growth factor, epidermal growth factor β, and insulin-like ... Neurotrophic factors such as NGF and growth differentiation factor 5 (GDF-5), however, are well established as promoters of ...

"Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation is mediated by hyaluronan (HA)- ... "Signalling by the type 1 insulin-like growth factor receptor: interplay with the epidermal growth factor receptor". Growth ... including epidermal growth factor and transforming growth factor alpha (TGF-α). ErbB2 has no known direct activating ligand, ... "Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor". Biochemistry. ...

Choy L, Derynck R (Mar 2003). "Transforming growth factor-beta inhibits adipocyte differentiation by Smad3 interacting with ... "C/EBPdelta expression in a BCR-ABL-positive cell line induces growth arrest and myeloid differentiation". Oncogene. 24 (9): ... Xia C, Cheshire JK, Patel H, Woo P (Dec 1997). "Cross-talk between transcription factors NF-kappa B and C/EBP in the ... The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA ...

Arsenic has been shown to alter epidermal keratinocyte differentiation processes, induce overexpression of growth factors, and ... November 1996). "Arsenic induces overexpression of growth factors in human keratinocytes". Toxicol. Appl. Pharmacol. 141 (1): ... "Arsenate perturbation of human keratinocyte differentiation". Cell Growth Differ. 5 (11): 1235-41. PMID 7848924. Archived from ... An arsenical keratosis is a growth of keratin on the skin caused by arsenic,: 725 which occurs naturally in the Earth's crust ...

Neurotrophic factors are polypeptides or small proteins that support the growth, differentiation, and survival of neurons. They ... Aberg D (2010). "Role of the growth hormone/insulin-like growth factor 1 axis in neurogenesis". Pediatric Neuroendocrinology. ... IGF-1 is a peptide and neurotrophic factor that mediates some of the effects of growth hormone; IGF-1 elicits its physiological ... Aerobic exercise increases the peripheral levels of growth factors (e.g., BDNF, IFG-1, and VEGF) which cross the blood-brain ...

... effects of nerve growth factor and granulocyte-macrophage colony-stimulating factor on human basophilic cell differentiation". ... 77 (5): 971-9. PMID 1995103. Kumar V, Abbas AK, Fausto N, Robbins SL, Cotran RS (2005). Robbins and Cotran pathologic basis of ...

Growth differentiation factor 6 (GDF6) is a regulatory protein associated with growth and differentiation of developing embryos ... Growth differentiation factor 6 (GDF6) is a protein that in humans is encoded by the GDF6 gene. GDF6 belongs to the ... 1997). "Ectopic induction of tendon and ligament in rats by growth and differentiation factors 5, 6, and 7, members of the TGF- ... 2005). "Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ...

The brain-derived neurotrophic factor (BDNF) gene plays a role in the growth, differentiation, and maintenance of neurons. ... Brain-derived neurotrophic factor (BDNF) plays a major role in both bipolar disorder and major depressive disorder. BDNF is a ... Lin CC, Huang TL (April 2020). "Brain-derived neurotrophic factor and mental disorders". Biomedical Journal. 43 (2): 134-142. ... Dwivedi Y (2012). "Brain-Derived Neurotrophic Factor in Suicide Pathophysiology". In Dwivedi Y (ed.). The Neurobiological Basis ...

Growth Factor Reviews. 67: 80-88. doi:10.1016/j.cytogfr.2022.06.003. PMID 35803833. Leonard WJ, Donlon TA, Lebo RV, Greene WC ( ... proliferation and cell growth, transcriptional regulation and cell differentiation. T lymphocytes are influenced by IL-2R ... Growth Factor Reviews. 67: 66-79. doi:10.1016/j.cytogfr.2022.06.004. PMID 35803834. El-Maraghy N, Ghaly MS, Dessouki O, Nasef ... Li Y, Li X, Geng X, Zhao H (October 2022). "The IL-2A receptor pathway and its role in lymphocyte differentiation and function ...

Growth differentiation factor 7 (GDF7) is a protein that in humans is encoded by the GDF7 gene. GDF7 belongs to the ... 1999). "Isolation of zebrafish gdf7 and comparative genetic mapping of genes belonging to the growth/differentiation factor 5, ... 2005). "Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ... transforming growth factor beta superfamily that is specifically found in a signaling center known as the roof plate that is ...

"Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing ... "Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing ... "Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing ... There are numbers of cytokines, transcription factors and other molecules, that have a role in TH9 differentiation. Cytokines ...

Neurturin Persephin Artemin Growth differentiation factor-9 (GDF9) Hepatocyte growth factor (HGF) Hepatoma-derived growth ... Fibroblast growth factor 1(FGF1) Fibroblast growth factor 2(FGF2) Fibroblast growth factor 3(FGF3) Fibroblast growth factor 4( ... Fibroblast growth factor 6(FGF6) Fibroblast growth factor 7(FGF7) Fibroblast growth factor 8(FGF8) Fibroblast growth factor 9( ... Fibroblast growth factor 10(FGF10) Fibroblast growth factor 11(FGF11) Fibroblast growth factor 12(FGF12) Fibroblast growth ...

TGF-β also plays a crucial role in stem cell differentiation as well as T-cell regulation and differentiation. Because of its ... Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily ... Hassan, Sobia; Shah, Hussain; Shawana, Summayya (2020). "Dysregulated epidermal growth factor and tumor growth factor-beta ... "Interactions between growth factors and integrins: latent forms of transforming growth factor-beta are ligands for the integrin ...

... cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. ... "Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor". Nature. 395 (6703): 713-6. Bibcode:1998Natur. ... "Contribution of the ERK5/MEK5 pathway to Ras/Raf signaling and growth control". The Journal of Biological Chemistry. 274 (44): ... is required for the differentiation of muscle cells". EMBO Reports. 2 (9): 829-34. doi:10.1093/embo-reports/kve177. PMC 1084032 ...

... and nerve growth factor-dependent differentiation signals in PC12 cells". Cell Growth & Differentiation. 9 (9): 757-66. PMID ... SHB (gene) has been shown to interact with: EPS8, Fibroblast growth factor receptor 1, Linker of activated T cells, Lymphocyte ... Hooshmand-Rad R, Lu L, Heldin CH, Claesson-Welsh L, Welsh M (Jun 2000). "Platelet-derived growth factor-mediated signaling ... Karlsson T, Kullander K, Welsh M (Sep 1998). "The Src homology 2 domain protein Shb transmits basic fibroblast growth factor- ...

Others (e.g., CD135) act as cell surface receptors for growth factors. Recently, the marker CD47 was found to have anti- ... The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD ... White Cell Differentiation Antigens. Oxford University Press. Knapp, W; et al. (1989). Leucocyte Typing IV. Oxford University ... Since 1982 there have been nine Human Leukocyte Differentiation Antigen Workshops culminating in a conference. The CD system is ...

Through development, the Fgf8 goes to regulate the growth and differentiation of progenitor cells in this region to produce ... "Role of fibroblast growth factor 8 in growth and progression of hormonal cancer". Cytokine & Growth Factor Reviews. 18 (3-4): ... May 2001). "Enhanced invasion and tumor growth of fibroblast growth factor 8b-overexpressing MCF-7 human breast cancer cells". ... "Human androgen-induced growth factor in prostate and breast cancer cells: its molecular cloning and growth properties". FEBS ...

... interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor ... Epidermal growth factor receptor family Epidermal growth factor receptor Receptor tyrosine-kinases GRCh38: Ensembl release 89: ... "Insulin-like growth factor-1 receptor inhibition induces a resistance mechanism via the epidermal growth factor receptor/HER3/ ... AKT signaling pathway: rational basis for cotargeting insulin-like growth factor-1 receptor and epidermal growth factor ...

... isolation and characterization of a new member of the family of human ETS transcription factors". Cell Growth & Differentiation ... Friend leukemia integration 1 transcription factor (FLI1), also known as transcription factor ERGB, is a protein that in humans ... "FLI1 and EWS-FLI1 function as ternary complex factors and ELK1 and SAP1a function as ternary and quaternary complex factors on ... Fli-1 is a member of the ETS transcription factor family that was first identified in erythroleukemias induced by Friend Murine ...

Shi GX, Andres DA (January 2005). "Rit contributes to nerve growth factor-induced neuronal differentiation via activation of B- ... 307 (5715): 1621-5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788. Benmaamar R, ...

Hill JJ, Qiu Y, Hewick RM, Wolfman NM (June 2003). "Regulation of myostatin in vivo by growth and differentiation factor- ... "Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11". The Journal of Biological ... "WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity". The FEBS Journal. ... 26 (5): 1374-82. doi:10.1519/JSC.0b013e318251083f. PMID 22395277. S2CID 12311653. Saremi A, Gharakhanloo R, Sharghi S, Gharaati ...

Benito M, Valverde AM, Lorenzo M (May 1996). "IGF-I: a mitogen also involved in differentiation processes in mammalian cells". ... "Signalling by the type 1 insulin-like growth factor receptor: interplay with the epidermal growth factor receptor". Growth ... insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a ... The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane ...