"B cell growth factors and B cell differentiation factor from human T hybridomas. Two distinct kinds of B cell growth factor and ... "B-cell growth factor (B-cell growth factor I or B-cell-stimulating factor, provisional 1) is a differentiation factor for ... "B-cell growth factor: distinction from T-cell growth factor and B-cell maturation factor". Proceedings of the National Academy ... B Cell Growth and Differentiation Factors (also known as BCGF and BCDF) are two important groups of soluble factors controlling ...
Growth differentiation factor 9 (GDF9) is an oocyte derived growth factor in the transforming growth factor β (TGF-β) ... Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. Growth differentiation factor-9 ... pathways for growth differentiation factor 9 and related orphan bone morphogenetic protein/growth differentiation factor ... Growth Differentiation Factor-9 Promotes the Growth, Development, and Survival of Human Ovarian Follicles in Organ Culture. The ...
Growth differentiation factors (GDFs) are a subfamily of proteins belonging to the transforming growth factor beta superfamily ... Andersson O, Reissmann E, Ibáñez C (2006). "Growth differentiation factor 11 signals through the transforming growth factor- ... "Growth/differentiation factor-10: a new member of the transforming growth factor-beta superfamily related to bone morphogenetic ... "Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following ...
... (also known as growth differentiation factor 8, abbreviated GDF8) is a protein that in humans is encoded by the MSTN ... Myostatin is a secreted growth differentiation factor that is a member of the TGF beta protein family. Myostatin is assembled ... "Growth/Differentiation factor 8 preproprotein [Homo sapiens] - Protein - NCBI". Ge G, Greenspan DS (March 2006). "Developmental ... Overview of all the structural information available in the PDB for UniProt: O08689 (Mouse Growth/differentiation factor 8) at ...
Growth/differentiation factor 5 is a protein that in humans is encoded by the GDF5 gene. The protein encoded by this gene is ... "Entrez Gene: GDF5 growth differentiation factor 5 (cartilage-derived morphogenetic protein-1)". O'Keeffe G, Dockery P, Sullivan ... Sullivan A, O'Keeffe G (2005). "The role of growth/differentiation factor 5 (GDF5) in the induction and survival of midbrain ... Buxton P, Edwards C, Archer C, Francis-West P (2001). "Growth/differentiation factor-5 (GDF-5) and skeletal development". J ...
Growth Factors, Differentiation Factors, and Cytokines. Berlin, Heidelberg: Springer. pp. 85-102. doi:10.1007/978-3-642-74856-1 ... T-cell replacing factor III, B-cell activating factor, B-cell differentiation factor, and "Heidikine") and interleukin 2 (TSF, ... These include granulocyte colony-stimulating factor (GCSF) and myelomonocytic growth factor (MGF). GCSF acts in hematopoiesis ... Interleukin 7 (IL-7) is a cytokine that serves as a growth factor for early lymphoid cells of both B- and T-cell lineages. ...
"Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior- ... May 2013). "Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy". Cell. 153 ... April 2021). "Growth differentiation factor 11: a "rejuvenation factor" involved in regulation of age-related diseases?". Aging ... April 2021). "Growth differentiation factor 11: a "rejuvenation factor" involved in regulation of age-related diseases?". Aging ...
Growth differentiation factor 1 (GDF1) is a protein that in humans is encoded by the GDF1 gene. GDF1 belongs to the ... Lee SJ (May 1991). "Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic ... Lee SJ (1991). "Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure". ... 2007). "Loss-of-function mutations in growth differentiation factor-1 (GDF1) are associated with congenital heart defects in ...
"The role of the epidermal growth factor-like protein dlk in cell differentiation". Histology and Histopathology. 15 (1): 119-29 ... A Novel Circulating Human Epidermal-Growth-Factor-Like Protein Expressed in Neuroendocrine Tumors and its Relation to the Gene ... a member of the epidermal growth factor superfamily, in neurofibromas and serum from patients with neurofibromatosis type 1". ... "The EGF-like Homeotic Protein dlk Affects Cell Growth and Interacts with Growth-Modulating Molecules in the Yeast Two-Hybrid ...
"Tat-induced deregulation of neuronal differentiation and survival by nerve growth factor pathway". J. Neurovirol. 8 Suppl 2 (2 ... "Extracellular signal-regulated kinase activated by epidermal growth factor and cell adhesion interacts with and phosphorylates ... Dinerstein-Cali H, Ferrag F, Kayser C, Kelly PA, Postel-Vinay M (August 2000). "Growth hormone (GH) induces the formation of ... differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by ...
October 2002). "M6a acts as a nerve growth factor-gated Ca(2+) channel in neuronal differentiation". Biochemical and ... 74 (1-2): 138-9. doi:10.1159/000134401. PMID 8893821. Yan Y, Narayanan V, Lagenaur C (July 1996). "Expression of members of the ...
2002). "Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 ( ... Lee SJ (Jun 1991). "Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic ... which also encodes growth differentiation factor 1. Ceramide synthase 1 (CerS1) is a ceramide synthase that catalyzes the ... Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in yeast ...
... (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with ... 1998). "A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4". J. Biochem. ... NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 5, Neurotrophic factors, ...
February 2006). "The transforming growth factor-beta superfamily member growth-differentiation factor-15 protects the heart ... "Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following ... Growth/differentiation factor 15 is a protein that in humans is encoded by the GDF15 gene. GDF15 was first identified as ... October 2007). "Growth differentiation factor 15 for risk stratification and selection of an invasive treatment strategy in non ...
"Transforming growth factor beta2 inhibits adipocyte differentiation induced by skeletal unloading in rat bone marrow stroma". ... a microenvironment that contains cells and secreted factors that promote appropriate renewal and differentiation of HSC. The ... Indeed, energy availability appears to be a factor in the ability of exercise to regulate BMAT. Another exception occurs in ... Thus, it is thought that BMAT results from preferential MSC differentiation into the adipocyte, rather than osteoblast, lineage ...
... a marker of differentiation in keratinocytes, by lens epithelium-derived growth factor (LEDGF)". J. Mol. Biol. 320 (5): 1053-63 ... "Lens epithelium-derived growth factor: effects on growth and survival of lens epithelial cells, keratinocytes, and fibroblasts ... Singh DP, Kimura A, Chylack LT, Shinohara T (2000). "Lens epithelium-derived growth factor (LEDGF/p75) and p52 are derived from ... The term LEDGF/p75 (Lens epithelium-derived growth factor) has entered common usage based on the initial characterization of ...
"Growth differentiation factor 9 and bone morphogenetic protein 15 are essential for ovarian follicular development in sheep". ... July 2000). "Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a ... Jennifer Juengel; McNatty KP (10 February 2005). "The role of proteins of the transforming growth factor-beta superfamily in ... 80 (1): 1-29. doi:10.1152/PHYSREV.2000.80.1.1. ISSN 0031-9333. PMID 10617764. Wikidata Q33807187. T Wilson; X Y Wu; J L Juengel ...
... signaling and promotes photoreceptor differentiation. Among other targets of miR-7 are insulin-like growth factor 1 receptor ( ... Webster RJ, Giles KM, Price KJ, Zhang PM, Mattick JS, Leedman PJ (February 2009). "Regulation of epidermal growth factor ... In Drosophila photoreceptor cells, miR-7 controls epidermal growth factor receptor (EGFR) ... insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells". The Biochemical Journal. 432 (1): 199-205. doi ...
Wanscher, Johan Henrik (1970). "The effect of genic time-factors upon differentiation and growth as seen in some snail shells ... 143: 1-19. doi:10.1127/arch.moll/1869-0963/143/001-019. Wikimedia Commons has media related to Liguus virgineus. Conchology ...
Ge B, Xiong X, Jing Q, Mosley JL, Filose A, Bian D, Huang S, Han J (2003). "TAB1beta (transforming growth factor-beta-activated ... Sakurai H, Miyoshi H, Toriumi W, Sugita T (May 1999). "Functional interactions of transforming growth factor beta-activated ... "Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of ... "Transforming growth factor-beta-activated kinase 1 is essential for differentiation and the prevention of apoptosis in ...
"Mechanochemical Switching between Growth and Differentiation during Fibroblast Growth Factor-stimulated Angiogenesis In Vitro: ... "On Growth and Form" at the Textile Museum of Canada in Toronto[citation needed]. Crow, James Mitchell (19 January 2015). "The ... Ingber, Donald (April 1, 2003). "Tensegrity I. Cell structure and hierarchical systems biology". Journal of Cell Science. 116 ( ... January 1, 2014. Retrieved 11 February 2015. "LIFETIME ACHIEVEMENT SYNOPSIS". Marquis Who's Who Ventures LLC. Retrieved 2019-01 ...
In synergy with other growth factors, Flt3 ligand stimulates the proliferation and differentiation of various blood cell ... it is a major growth factor stimulating the growth of dendritic cells. FLT3L functions as a cytokine and growth factor that ... It is structurally homologous to stem cell factor (SCF) and colony stimulating factor 1 (CSF-1). ... April 1994). "Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by ...
Growth factors: Growth factors can be used to induce differentiation of a cell or induce secretion of matrix proteins. Common ... Transforming Growth Factor β (TGF- β), Bone Morphogenic Proteins (BMP) and Growth and Differentiation Factor 5 (GDF-5). Human ... growth factors for the application of synthetic cartilage include Insulin-growth factor 1 (IGF-1), ... Additionally, growth factors have been thoroughly evaluated; however, specific combinations still need to be studied further in ...
December 2012). "The hedgehog system machinery controls transforming growth factor-β-dependent myofibroblastic differentiation ... a member of the BMP growth factor family). For other Hh-regulated genes, expression requires not only the loss of CiR but also ... This diffusible factor was later shown to be Sonic hedgehog. However, precisely how SHH determines digit identity remained ... They showed that identity of the digits in the chick limb was determined by a diffusible factor produced by the zone of ...
... enhances lung myofibroblast differentiation through transforming growth factor β receptor-dependent and -independent pathways ... The protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation ... AE binding protein 1 is a protein that in humans is encoded by the AEBP1 gene. AE binding protein 1 is a member of ... "Entrez Gene: AE binding protein 1". Human AEBP1 genome location and AEBP1 gene details page in the UCSC Genome Browser. Tumelty ...
"Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation". ... Spivak-Kroizman T, Mohammadi M, Hu P, Jaye M, Schlessinger J, Lax I (May 1994). "Point mutation in the fibroblast growth factor ... Curto M, Frankel P, Carrero A, Foster DA (February 1998). "Novel recruitment of Shc, Grb2, and Sos by fibroblast growth factor ... Schroeder JA, Thompson MC, Gardner MM, Gendler SJ (April 2001). "Transgenic MUC1 interacts with epidermal growth factor ...
In fact, sElk1 counteracts Elk1 in neuronal differentiation and the regulation of nerve growth factor/ERK signaling. The ... in nerve growth factor-induced PC12 differentiation". J. Biol. Chem. 276 (7): 5189-96. doi:10.1074/jbc.M006678200. PMID ... Raf itself is activated by Ras, which is linked to growth factor receptors with tyrosine kinase activity via Grb2 and Sos. Grb2 ... The B domain allows Elk1 to bind to a dimer of its cofactor, serum response factor (SRF). Located adjacent to the B domain, the ...
... making PDGF a more viable growth factor for osteogenic differentiation than other, more expensive growth factors currently used ... Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In ... Other growth factors in this family include vascular endothelial growth factors B and C (VEGF-B, VEGF-C) which are active in ... PDGF was one of the first growth factors characterized, and has led to an understanding of the mechanism of many growth factor ...
... (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. ... Epidermal growth factor has been shown to interact with epidermal growth factor receptors. Recombinant human epidermal growth ... Besides EGF itself other family members include: Heparin-binding EGF-like growth factor (HB-EGF) transforming growth factor-α ( ... Polypeptide growth factors include: EGF acts by binding with high affinity to epidermal growth factor receptor (EGFR) on the ...
Chan SS, Schedlich LJ, Twigg SM, Baxter RC (April 2009). "Inhibition of adipocyte differentiation by insulin-like growth factor ... Many factors increase IGFBP-3 production by cells, including transforming growth factor-β (TGFβ), tumor necrosis factor-α, ... "Potentiation of growth factor signaling by insulin-like growth factor-binding protein-3 in breast epithelial cells requires ... "Synthesis of insulin-like growth factor binding proteins and of the acid-labile subunit of the insulin-like growth factor ...