Root RK, Dale DC (March 1999). "Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor: ... a granulocyte colony-stimulating factor (G-CSF) analog) Granulocyte-macrophage colony-stimulating factor receptor Lenzilumab ... Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric ... "Granulocyte-macrophage colony-stimulating factor: not just another haematopoietic growth factor". Medical Oncology. 31 (1): 774 ...
... is a receptor for granulocyte-macrophage colony-stimulating factor, which stimulates the production of white blood cells. In ... The granulocyte-macrophage colony-stimulating factor receptor also known as CD116 (Cluster of Differentiation 116), ... Lia F, Rajotte D, Clark SC, Hoang T (Nov 1996). "A dominant negative granulocyte-macrophage colony-stimulating factor receptor ... Doyle SE, Gasson JC (Aug 1998). "Characterization of the role of the human granulocyte-macrophage colony-stimulating factor ...
"Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) secretion by ... Granulocyte colony-stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein ... Metcalf D (July 1985). "The granulocyte-macrophage colony-stimulating factors". Science. 229 (4708): 16-22. Bibcode:1985Sci... ... Duarte RF, Franf DA (June 2002). "The synergy between stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF ...
... (tradename Leukine) is a recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) that functions as ... "Emerging applications of recombinant human granulocyte-macrophage colony-stimulating factor". Blood. 92 (12): 4491-508. doi: ... macrophages, and, myeloid-derived dendritic cells; it can also activate mature granulocytes and macrophages, and can contribute ...
One notable example is the granulocyte macrophage colony-stimulating factor. The goal of this stimulated immune response is ... The goal is to stimulate the person's immune system in order to prevent future infections that may result in an acute episode ... For example, female sex hormones are known to stimulate both adaptive and innate immune responses. Some autoimmune diseases ... Dorshkind, Kenneth; Horseman, Nelson D. (1 June 2000). "The Roles of Prolactin, Growth Hormone, Insulin-Like Growth Factor-I, ...
Production is stimulated by granulocyte macrophage colony-stimulating factor (GM-CSF). There is some controversy over which ... CFU-GM, also known as granulocyte-macrophage progenitor (GMP), is a colony forming unit. It is derived from CFU-GEMM. The "GM" ... ISBN 0-8385-8285-0. CFU-GM at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Colony forming units ... Nomenclature of hematopoietic colonies and lineages "Hem I WBC Morphology and Physiology". Archived from the original on ...
El Ouakfaoui S, Heitz D, Paquin R, Beaulieu AD (February 1999). "Granulocyte-macrophage colony-stimulating factor modulates ...
IL-3 shares the β subunit with IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF). This β subunit sharing ... Granulocyte macrophage colony-stimulating factor (GM-CSF), and IL-6. IL-3 is secreted by basophils and activated T cells to ... "Granulocyte-Macrophage colony stimulating factor and interleukin 3: Target cells and kinetics of response in vivo". Stem Cells ... of granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and interleukin-5 (IL-5) receptor complexes ...
March 1985). "Structure and expression of the mRNA for murine granulocyte-macrophage colony stimulating factor". The EMBO ... Ludwig researchers in Melbourne discovered and cloned the granulocyte-monocyte colony-stimulating factor (GM-CSF) through a ... The factor is essential to the maturation of key white blood cells, and has been used extensively over the past few decades to ... October 1985). "Purification and characterization of a human tumor necrosis factor from the LuKII cell line". Proceedings of ...
In EG cytokines IL-3, IL-5 and granulocyte macrophage colony stimulating factor (GM-CSF) may be behind the recruitment and ... granulocyte-macrophage colony-stimulating factor, and interleukin 5 in eosinophilic gastroenteritis". Gastroenterology. 110 (3 ...
In EG cytokines IL-3, IL-5 and granulocyte macrophage colony stimulating factor (GM-CSF) may be behind the recruitment and ... granulocyte-macrophage colony-stimulating factor, and interleukin 5 in eosinophilic gastroenteritis". Gastroenterology. 110 (3 ...
In addition, it expresses granulocyte-macrophage colony-stimulating factor to stimulate immune responses. In nonclinical ... and it has been engineered to express the granulocyte-macrophage colony-stimulating factor gene to stimulate a systemic anti- ... granulocyte-macrophage colony-stimulating factor]) next generation of the VVDD series A phase 3 randomized, open-label, ... JX-929's tumor selectivity has been optimized through deletion of thymidine kinase and vaccinia growth factor. JX-929 has been ...
Granulocyte-macrophage colony stimulating factor (GM-CSF) is sometimes used in neonatal sepsis. However, a 2009 study found ... Carr R, Brocklehurst P, Doré CJ, Modi N (January 2009). "Granulocyte-macrophage colony stimulating factor administered as ... Infants showing no signs of neonatal sepsis will have a sepsis workup done only if concerning factors are shown. Only a small ... The child can contribute to the onset of sepsis through multiple factors. Mothers contribute to the risk through a variety of ...
Granulocyte-macrophage colony-stimulating factor (GM-CSF) hypersensitivity of myeloid progenitors in vitro. These criteria are ... Immature granulocytes and nucleated red cells in the peripheral blood. White blood cell count >10 x 109/L. Clonal chromosomal ...
... is a recombinant granulocyte macrophage colony-stimulating factor which functions as an immunostimulator. Quittet ...
Granulocyte-macrophage colony stimulating factor expands the circulating hematopoietic progenitor cell compartment in humans, ... The effect of recombinant human granulocyte-macrophage colony stimulating factor on chemotherapy-induced myelosuppression. N ... Antman developed standards for the treatment of patients receiving chemotherapy including pharmacology, growth factors and ...
Granulocyte-macrophage colony-stimulating factor (GM-CSF) upregulates CCL17 production in monocytes and macrophages. Dendritic ... January 1998). "Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4". The Journal of Biological ... It does not interact with granulocytes. It acts as a powerful chemoattractant to T-helper cells and T-regulatory cells because ... CCL17 is a powerful chemokine produced in the thymus and by antigen-presenting cells like dendritic cells, macrophages, and ...
... a Conditionally Replicating Granulocyte Macrophage Colony-Stimulating Factor-Armed Oncolytic Adenovirus for the Treatment of ... "Oncolytic Adenovirus Coding for Granulocyte Macrophage Colony-Stimulating Factor Induces Antitumoral Immunity in Cancer ... adenoviruses have been genetically modified with transgene encoding for granulocyte-macrophage colony-stimulating factor (GM- ... p53 is a transcription factor that plays a role in apoptosis, cell cycle and DNA repair. It blocks cell progression in response ...
1995). "Association of granulocyte-macrophage colony-stimulating factor with the crystalloid granules of human eosinophils". ... 1992). "Purification and cDNA cloning of a novel factor produced by a human T-cell hybridoma: sequence homology with animal ... and activates neutrophils and alveolar macrophages. Structurally the major basic protein (MBP) is similar to lectins (sugar- ...
"Oncolytic adenovirus coding for granulocyte macrophage colony-stimulating factor induces antitumoral immunity in cancer ...
Secondary structure analysis has suggested similarity to IL4 and granulocyte-macrophage colony stimulating factor (GMCSF). ... These include granulocyte colony-stimulating factor (GCSF) and myelomonocytic growth factor (MGF). GCSF acts in hematopoiesis ... "Disulfide structures of human interleukin-6 are similar to those of human granulocyte colony stimulating factor". Archives of ... "Characterization of a human multilineage-colony-stimulating factor cDNA clone identified by a conserved noncoding sequence in ...
To engineer JX-594, human GMCSF gene (encoding granulocyte macrophage colony-stimulating factor or GM-CSF; driven by a ...
Recombinant granulocyte-macrophage colony-stimulating factor (rGM-CSF) can be used as a temporary cure. GM-CSF stimulates ... If the results show patients with low levels of lymphocytes, absence of granulocytes or absence of thymus then the patient may ...
In patients with very low white blood cell counts, granulocyte-macrophage colony-stimulating factor may be given. Depending on ... to 2010 in a university hospital in Mexico shows that neutropenia in immunocompromised patients is the most common risk factor ...
"Association of CrkL with STAT5 in hematopoietic cells stimulated by granulocyte-macrophage colony-stimulating factor or ... "Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the ... van Dijk TB, van Den Akker E, Amelsvoort MP, Mano H, Löwenberg B, von Lindern M (November 2000). "Stem cell factor induces ... Sattler M, Salgia R, Shrikhande G, Verma S, Pisick E, Prasad KV, Griffin JD (April 1997). "Steel factor induces tyrosine ...
Lehmann MH (June 1998). "Recombinant human granulocyte-macrophage colony-stimulating factor triggers interleukin-10 expression ... U-937-derived macrophages preferentially respond to M2-inducing stimuli, subsequently leading them to acquire the phenotype of ... Whereas, in the case of THP-1 cells, the polarization is reversed in favor of classical M1 macrophages. Both cell lines can be ... The only difference being that the M1 phenotype establishment in U-937-derived macrophages will not be as strong as in THP-1, ...
"Association of CrkL with STAT5 in hematopoietic cells stimulated by granulocyte-macrophage colony-stimulating factor or ... The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth ... Liao, Z; Lutz, J; Nevalainen, MT (February 2010). "Transcription factor Stat5a/b as a therapeutic target protein for prostate ... STAT5A has been shown to interact with: CRKL, Epidermal growth factor receptor, ERBB4, Erythropoietin receptor, Janus kinase 1 ...
"Synergistic effects of nerve growth factor and granulocyte-macrophage colony-stimulating factor on human basophilic cell ... CFU-Baso is a colony forming unit. that gives rise to basophils. Some sources use the term "CFU-Bas". Tsuda T, Wong D, Dolovich ... ISBN 978-1-85317-676-0. v t e (Colony forming units, Blood cells, All stub articles, Cell biology stubs). ...
September 1998). "A plasmid encoding murine granulocyte-macrophage colony-stimulating factor increases protection conferred by ... Stimulated macrophages secrete IL-12, IL-18, TNF-α, IFN-α, IFN-β and IFN-γ, while stimulated B-cells secrete IL-6 and some IL- ... However, they can also be stimulated to secrete antiviral cytokines such as IFN-γ and TNF-α, which do not kill the cell, but ... Macrophage scavenger receptors bind to a variety of macromolecules, including polyribonucleotides and are thus candidates for ...
Harada T, Ohno N (2008). "Contribution of dectin-1 and granulocyte macrophage-colony stimulating factor (GM-CSF) to ... Experiments suggest that S. crispa contains chemicals that may stimulate the immune system and has many biological properties ... mitogen-activated protein kinase and nuclear factor-κB". Int. J. Mol. Med. 30 (2): 344-50. doi:10.3892/ijmm.2012.1000. PMID ...